Intravitreal Therapeutic Nanoparticles For The Treatment Of Posterior Segment Ocular Diseases

Download Intravitreal Therapeutic Nanoparticles For The Treatment Of Posterior Segment Ocular Diseases full books in PDF, epub, and Kindle. Read online Intravitreal Therapeutic Nanoparticles For The Treatment Of Posterior Segment Ocular Diseases ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Intravitreal Therapeutic Nanoparticles for the Treatment of Posterior Segment Ocular Diseases

Author : Joel Grondek
Publisher :
ISBN 13 :
Total Pages : 146 pages
Book Rating : 4.:/5 (13 download)

DOWNLOAD NOW!

Book Synopsis Intravitreal Therapeutic Nanoparticles for the Treatment of Posterior Segment Ocular Diseases by : Joel Grondek

Download or read book Intravitreal Therapeutic Nanoparticles for the Treatment of Posterior Segment Ocular Diseases written by Joel Grondek and published by . This book was released on 2022 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular therapeutic delivery affords challenges as unique as the diseases themselves. The human eye is anatomically compartmentalized, both within the organ itself and from the systemic vasculature typically used for drug delivery. Recent pharmaceutical developments have revolutionized the prognosis for ocular diseases, yet many therapies treating the posterior segment of the eye remain invasive and require frequent administration to maintain remission. Herein, we review the application of nanocarriers as intravitreally injected therapeutic delivery vehicles working toward enhanced retinal uptake to further improve current therapeutic outcomes and for the development future therapies and we present a novel approach to the treatment of diabetic retinopathy and diabetic macular edema. Chapter one provides introductory overview of the complex anatomy of the eye, routes of therapeutic administration, and current nanoparticle formulations designed to treat posterior segment diseases by intravitreal injection. Chapter two demonstrates a novel application of fusogenic porous silicon nanoparticles for intravitreal delivery of vascular endothelial growth factor siRNA using a rabbit model for diabetic retinopathy and diabetic macular edema. Chapter three summaries prior work focused on peptide targeted magnetic resonance imaging of myocardial infarction using a fibrin homing peptide. Here we demonstrate long circulating iron oxide nanoparticle chains call "nanoworms" can effectively target early fibrin associated with myocardial injury using a rat ischemia/reperfusion model.

Drug Delivery for the Retina and Posterior Segment Disease

Author : Jayvadan K. Patel
Publisher : Springer
ISBN 13 : 3319958070
Total Pages : 490 pages
Book Rating : 4.3/5 (199 download)

DOWNLOAD NOW!

Book Synopsis Drug Delivery for the Retina and Posterior Segment Disease by : Jayvadan K. Patel

Download or read book Drug Delivery for the Retina and Posterior Segment Disease written by Jayvadan K. Patel and published by Springer. This book was released on 2018-10-08 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.

Drug Product Development for the Back of the Eye

Author : Uday B. Kompella
Publisher : Springer Science & Business Media
ISBN 13 : 1441999205
Total Pages : 596 pages
Book Rating : 4.4/5 (419 download)

DOWNLOAD NOW!

Book Synopsis Drug Product Development for the Back of the Eye by : Uday B. Kompella

Download or read book Drug Product Development for the Back of the Eye written by Uday B. Kompella and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.

Ocular Drug Delivery Systems

Author : Deepak Thassu
Publisher : CRC Press
ISBN 13 : 1439848009
Total Pages : 477 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Ocular Drug Delivery Systems by : Deepak Thassu

Download or read book Ocular Drug Delivery Systems written by Deepak Thassu and published by CRC Press. This book was released on 2012-10-02 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye. With contributions from leading pharmaceutical researchers and industry experts, eye researchers, surgeons, pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis, the book presents the state of the art in the use of nanoparticles in ocular drug delivery systems and also sets the stage for future developments. This volume provides both a current evaluation and a future roadmap for developments in ocular drug delivery. The subjects range from biological needs to material challenges and finally to clinical applications for improving drug delivery for conditions where treatments already exist. It also explores areas where effective drugs may be currently available but yet need a safe, efficient, and efficacious delivery vehicle.

Focal Controlled Drug Delivery

Author : Abraham J. Domb
Publisher : Springer Science & Business Media
ISBN 13 : 1461494346
Total Pages : 700 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!

Book Synopsis Focal Controlled Drug Delivery by : Abraham J. Domb

Download or read book Focal Controlled Drug Delivery written by Abraham J. Domb and published by Springer Science & Business Media. This book was released on 2014-02-17 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.

Nanomaterial-Mediated Drug Delivery in Eye Diseases

Author : Yan Zhang
Publisher : Scientific Research Publishing, Inc. USA
ISBN 13 : 1649977042
Total Pages : 98 pages
Book Rating : 4.6/5 (499 download)

DOWNLOAD NOW!

Book Synopsis Nanomaterial-Mediated Drug Delivery in Eye Diseases by : Yan Zhang

Download or read book Nanomaterial-Mediated Drug Delivery in Eye Diseases written by Yan Zhang and published by Scientific Research Publishing, Inc. USA. This book was released on 2023-08-08 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topical application of conventional eye drops has been the prevalent route of ocular drug administration with good patient compliance. However, multiple physiological barriers in the eye significantly limit therapeutic efficacy of drugs. Recently, nanoparticle-mediated drug delivery system has emerged as a promising and effective tool to overcome the limitations of conventional drug formulations in the eye. This brochure sought to summarize and analyze the characteristics of several commonly-used nanoparticle-based delivery systems as well as the applications of the drug-loaded nanoparticles to the treatment of blinding ocular diseases, including inflammatory/ immune, vascular, and degenerative eye diseases.

Ophthalmic Drug Delivery Systems

Author : Ashim K. Mitra
Publisher : CRC Press
ISBN 13 : 9780367446765
Total Pages : 847 pages
Book Rating : 4.4/5 (467 download)

DOWNLOAD NOW!

Book Synopsis Ophthalmic Drug Delivery Systems by : Ashim K. Mitra

Download or read book Ophthalmic Drug Delivery Systems written by Ashim K. Mitra and published by CRC Press. This book was released on 2019-12-02 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Role of Novel Drug Delivery Vehicles in Nanobiomedicine

Author : Rajeev K. Tyagi
Publisher : BoD – Books on Demand
ISBN 13 : 1789239850
Total Pages : 196 pages
Book Rating : 4.7/5 (892 download)

DOWNLOAD NOW!

Book Synopsis Role of Novel Drug Delivery Vehicles in Nanobiomedicine by : Rajeev K. Tyagi

Download or read book Role of Novel Drug Delivery Vehicles in Nanobiomedicine written by Rajeev K. Tyagi and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Nanotechnology and Nanomedicine introduces non-experts to the world of nanomedicine and its evolving organizational infrastructure. Considering the fluid nature of nano breakthroughs and the delicate balance between benefits and consequences as they apply to medicine, readers at all levels will gain a practical, understandable base of information on these developments so that they may take the greatest advantage of them. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects and provides an ideal foundation upon which to plan and make decisions.

Treatment of Non-infectious Uveitis

Author : Phoebe Lin
Publisher : Springer Nature
ISBN 13 : 3030228274
Total Pages : 205 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Treatment of Non-infectious Uveitis by : Phoebe Lin

Download or read book Treatment of Non-infectious Uveitis written by Phoebe Lin and published by Springer Nature. This book was released on 2019-09-12 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique, comprehensive book provides a much-needed reference on the treatment and management of non-infectious uveitis. Carefully designed, Treatment of Non-infectious Uveitis is the first book of its kind to provide an in-depth, clinically-relevant, expert-driven resource for ophthalmologists focusing on modalities of uveitis treatment, their mechanism of action, dosing, and side effects. Each chapter provides an introduction, mechanism of action, indication, dosage, side effects, and efficacy summaries from clinical trials and other published literature. Topics range from topical treatment, to locally administered therapy including drug-releasing implants, to systemic immunosuppressive treatments both tried and new, as well as surgical management, with each chapter highlighting important practice pearls as well as easy-reference dosing tables, side effects, and lab monitoring pertinent to the agents discussed. The book concludes with a discussion of novel approaches to the treatment of non-infectious uveitis, and special considerations when treating uveitis in the pediatric patient. The majority of patients with non-infectious uveitis are treated by comprehensive ophthalmologists, many of whom are less familiar with established treatment guidelines outlining the role of corticosteroids and immunomodulatory therapy. While the non-specialist, resident, or fellow is sure to benefit from this one-stop guide to uveitis treatment, retina and uveitis specialists alike will also appreciate the practice tips and thorough coverage of this expertly-written reference. Treatment of Non-infectious Uveitis is the ideal reference for all ophthalmologists who seek to improve their understanding of the causes of uveitis and learn how to best treat this condition.

Breaking Down the Barrier

Author : Arturo Santos
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

DOWNLOAD NOW!

Book Synopsis Breaking Down the Barrier by : Arturo Santos

Download or read book Breaking Down the Barrier written by Arturo Santos and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topical instillation is the most widely preferred noninvasive route of drug administration to treat diseases affecting the anterior segment of the eye. Nonetheless, the ocular bioavailability for deeper ocular tissues is very low. Different routes of administration, such as intravitreal injections, periocular injections, and systemic administration, have been used to deliver drugs into the posterior segment ocular tissues. However, the presence of blood-retinal barriers (BRBs) makes systemic administration an impractical approach, whereas the drug delivery with the periocular administration route is compromised by ocular static and dynamic barriers. On the other hand, intravitreal injection, the most common and widely recommended route for drug administration to treat posterior ocular diseases, is related to several side effects such as endophthalmitis, hemorrhage, retinal detachment, and poor patient tolerance. Diverse strategies to overcome ocular barriers have been explored for topical drop formulations in order to deliver drugs into the posterior segment ocular tissues. In this chapter, we will review the promising topical nanocarriers for drug delivery into the posterior segment of the eye, emphasizing the use of liposomes for topical ophthalmic formulations targeting the vitreous cavity and the retina.

Ocular Drug Delivery: Advances, Challenges and Applications

Author : Richard T. Addo
Publisher : Springer
ISBN 13 : 3319476912
Total Pages : 190 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Ocular Drug Delivery: Advances, Challenges and Applications by : Richard T. Addo

Download or read book Ocular Drug Delivery: Advances, Challenges and Applications written by Richard T. Addo and published by Springer. This book was released on 2016-11-16 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye. Therefore, ocular drug delivery has been a major challenge to drug delivery researchers. There are on-going studies, in search of treatment especially for the diseases affecting the posterior segment of the eye. This book gives and overview of the background of ocular drug delivery and is unique for pharmacists, medical practitioners, students and drug delivery researchers.

Intraocular Drug Delivery

Author : Glenn J. Jaffe
Publisher : CRC Press
ISBN 13 : 1420016504
Total Pages : 385 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!

Book Synopsis Intraocular Drug Delivery by : Glenn J. Jaffe

Download or read book Intraocular Drug Delivery written by Glenn J. Jaffe and published by CRC Press. This book was released on 2006-03-13 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-r

Nanoscience: Friction And Rheology On The Nanometer Scale

Author : Ernst Meyer
Publisher : World Scientific
ISBN 13 : 981449934X
Total Pages : 393 pages
Book Rating : 4.8/5 (144 download)

DOWNLOAD NOW!

Book Synopsis Nanoscience: Friction And Rheology On The Nanometer Scale by : Ernst Meyer

Download or read book Nanoscience: Friction And Rheology On The Nanometer Scale written by Ernst Meyer and published by World Scientific. This book was released on 1998-12-30 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Friction force microscopy is an important analytical tool in the field of tribology on the nanometer-scale. The contact area between the probing tip and the sample is reduced to some square nanometers, corresponding to the ideal of a single asperity contact. Traditional concepts, such as friction coefficients, adhesion and elasticity and stick-slip are re-examined with this novel technique. New concepts based upon classical and quantum mechanics are investigated.

Common Eye Diseases and their Management

Author : Nicholas Robert Galloway
Publisher : Springer Science & Business Media
ISBN 13 : 144713625X
Total Pages : 281 pages
Book Rating : 4.4/5 (471 download)

DOWNLOAD NOW!

Book Synopsis Common Eye Diseases and their Management by : Nicholas Robert Galloway

Download or read book Common Eye Diseases and their Management written by Nicholas Robert Galloway and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rich and colorful illustration Problem-oriented approach Technical terms are avoided, when they can be replaced with plain English Book deals with the science of Ophthalmology at a basic level Text concentrates on eye diseases which are likely to be seen by general practitioners and optometrists at the primary care level Ideal for students

Microneedles for Drug and Vaccine Delivery and Patient Monitoring

Author : Ryan F. Donnelly
Publisher : John Wiley & Sons
ISBN 13 : 1119305179
Total Pages : 458 pages
Book Rating : 4.1/5 (193 download)

DOWNLOAD NOW!

Book Synopsis Microneedles for Drug and Vaccine Delivery and Patient Monitoring by : Ryan F. Donnelly

Download or read book Microneedles for Drug and Vaccine Delivery and Patient Monitoring written by Ryan F. Donnelly and published by John Wiley & Sons. This book was released on 2018-06-04 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of microneedles for delivering and monitoring patient drugs and vaccines Microneedles are an incredibly active research area and have the potential to revolutionize the way many medicines and vaccines are delivered. This comprehensive research book covers the major aspects relating to the use of microneedle arrays in enhancing both transdermal and intradermal drug delivery and provides a sound background to the use of microneedle arrays in enhanced delivery applications. Beginning with a history of the field and the various methods employed to produce microneedles from different materials, Microneedles for Drug and Vaccine Delivery and Patient Monitoring discusses the penetration of the stratum corneum by microneedles and the importance of application method and force and microneedle geometry (height, shape, inter-needle spacing). Transdermal and intradermal delivery research using microneedles is comprehensively and critically reviewed, focusing on the outcomes of in vivo animal and human studies. The book describes the important topics of safety and patient acceptability studies carried out to date. It also covers in detail the growing area for microneedle use in the monitoring of interstitial fluid contents. Finally, it reviews translational and regulatory developments in the microneedles field and describes the work ongoing in industry. The only book currently available on microneedles Filled with tables, graphs, and black and white images (photographs, micrographs) Authored by four experts in pharmaceutics Microneedles for Drug and Vaccine Delivery and Patient Monitoring is an ideal source for researchers in industry and academia working on drug delivery and transdermal delivery in particular, as well as for advanced students in pharmacy and pharmaceutical sciences.

Retinal Pharmacotherapeutics

Author : Q.D. Nguyen
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318055654
Total Pages : 426 pages
Book Rating : 4.3/5 (18 download)

DOWNLOAD NOW!

Book Synopsis Retinal Pharmacotherapeutics by : Q.D. Nguyen

Download or read book Retinal Pharmacotherapeutics written by Q.D. Nguyen and published by Karger Medical and Scientific Publishers. This book was released on 2015-10-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

Fundamentals of Nanoparticles

Author : Abdel Salam Hamdy Makhlouf
Publisher : William Andrew
ISBN 13 : 0128135174
Total Pages : 668 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Fundamentals of Nanoparticles by : Abdel Salam Hamdy Makhlouf

Download or read book Fundamentals of Nanoparticles written by Abdel Salam Hamdy Makhlouf and published by William Andrew. This book was released on 2018-08-09 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Nanoparticles: Classifications, Synthesis Methods, Properties and Characterization explores the nanoparticles and architecture of nanostructured materials being used today in a comprehensive, detailed manner. This book focuses primarily on the characterization, properties and synthesis of nanoscale materials, and is divided into three major parts. This is a valuable reference for materials scientists, and chemical and mechanical engineers working in R&D and academia, who want to learn more about how nanoparticles and nanomaterials are characterized and engineered. Part one covers nanoparticles formation, self-assembly in the architecture nanostructures, types and classifications of nanoparticles, and signature physical and chemical properties, toxicity and regulations. Part two presents different ways to form nanometer particles, including bottom-up and top-down approaches, the classical and non-classical theories of nanoparticles formation and self-assembly, surface functionalization and other surface treatments to allow practical use. Part three covers characterization of nanoparticles and nanostructured materials, including the determination of size and shape, in addition to atomic and electronic structures and other important properties. Includes new physical and chemical techniques for the synthesis of nanoparticles and architecture nanostructures Features an in-depth treatment of nanoparticles and nanostructures, including their characterization and chemical and physical properties Explores the unusual properties of materials that are developed by modifying their shape and composition and by manipulating the arrangement of atoms and molecules Explains important techniques for the synthesis, fabrication and the characterization of complex nano-architectures