Stem Cell-based Therapy for Neurodegenerative Diseases

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Author :
Publisher : Springer Nature
ISBN 13 : 9811543704
Total Pages : 144 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Stem Cell-based Therapy for Neurodegenerative Diseases by : Fabin Han

Download or read book Stem Cell-based Therapy for Neurodegenerative Diseases written by Fabin Han and published by Springer Nature. This book was released on 2020-10-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.

Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0323997783
Total Pages : 364 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors Part A by :

Download or read book Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors Part A written by and published by Elsevier. This book was released on 2023-10-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Volume 171 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on Neurodegenerative diseases, Stress induced exacerbation of Alzheimer's disease brain pathology is thwarted by co-administration of nanowired cerebrolysin and amyloid beta peptide antibodies with serotonin 5-HT6 receptor antagonist SB-39988, Nanowired delivery of dl-3-n-butylphthalide with antibodies to alpha synuclein potentiated neuroprotection in Parkinson's disease with emotional stress, Efficacy of invasive and non-invasive methods for the treatment of Parkinson ́s disease: nanodelivery and enriched environment, and much more. Other sections cover Sleep deprivation induced exacerbation of Parkinson's disease pathophysiology is attenuated by co-administration of nanowired cerebrolysin and serotonin-3 receptor antagonist ondansetron, Co-administration of DL-3-n-butylphthalide and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Stress and brain diseases, Pathophysiology of sleep deprivation enhances amyloid beta peptide and p-tau in the CSF and brain, Neuroprotective effects of nanowired delivery of multimodal drug cerebrolysin and monoclonal 5-HT antibodies, Prior heat exposure exacerbates brain blast injury, Neuroprotection by nanodelivery of cerebrolysin with serotonin 6 receptor antagonist SB-399885, the Effects of curcumin nanodelivery on several brain pathologies, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Internation Review on Neurobiology series Updated release includes the latest information on Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors

Handbook on Risk and Inequality

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Author :
Publisher : Edward Elgar Publishing
ISBN 13 : 1788972260
Total Pages : 293 pages
Book Rating : 4.7/5 (889 download)

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Book Synopsis Handbook on Risk and Inequality by : Curran, Dean

Download or read book Handbook on Risk and Inequality written by Curran, Dean and published by Edward Elgar Publishing. This book was released on 2022-09-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique Handbook charts shifts in the relationship between risks and inequalities over the last few decades, analysing how inequalities shape risk and how risks condition and intensify inequalities. Expert contributors examine the impacts of environmental, financial, social, urban, economic, and digital risks on inequalities, at both national and global levels.

Modern Approaches to Augmentation of Brain Function

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Publisher : Springer Nature
ISBN 13 : 3030545644
Total Pages : 747 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Modern Approaches to Augmentation of Brain Function by : Ioan Opris

Download or read book Modern Approaches to Augmentation of Brain Function written by Ioan Opris and published by Springer Nature. This book was released on 2021-08-25 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers recent advances in neural technology that provide for enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits involved in perception, cognition, emotion and action, that represent the building blocks of behavior and cognition. Augmentation of brain function can be achieved by using brain implants for recordings, stimulation, or drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. This volume evaluates existing methods of brain augmentation while discussing the brain circuitry and neuronal mechanisms that make augmentation possible. This volume offers novel insights into brain disorders, and explores new devices for brain repair while also addressing the philosophical and ethical implications of brain augmentation. The information in this book is relevant to researchers in the fields of neuroscience, engineering, and clinical practice. Advance Praise for Modern Approaches to Augmentation of Brain Function: “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” Ray Kurzweil, best-selling author, inventor, entrepreneur and a recipient of the National Medal of Technology and Innovation (1999), and the Lemelson-MIT Prize (2001) "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " Ioan Dumitrache, Prof. Dr. Eng. Faculty of Computer Science, Polytechnic University of Bucharest, Bucharest, Romania “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” György Buzsáki, MD, PhD is the Biggs Professor of Neuroscience, NYU School of Medicine, New York, NY

Biomedical Odysseys

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Publisher : Princeton University Press
ISBN 13 : 1400885280
Total Pages : 315 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Biomedical Odysseys by : Priscilla Song

Download or read book Biomedical Odysseys written by Priscilla Song and published by Princeton University Press. This book was released on 2017-05-16 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of people from more than eighty countries have traveled to China since 2001 to undergo fetal cell transplantation. Galvanized by the potential of stem and fetal cells to regenerate damaged neurons and restore lost bodily functions, people grappling with paralysis and neurodegenerative disorders have ignored the warnings of doctors and scientists back home in order to stake their futures on a Chinese experiment. Biomedical Odysseys looks at why and how these individuals have entrusted their lives to Chinese neurosurgeons operating on the forefront of experimental medicine, in a world where technologies and risks move faster than laws can keep pace. Priscilla Song shows how cutting-edge medicine is not just about the latest advances in biomedical science but also encompasses transformations in online patient activism, surgical intervention, and borderline experiments in health care bureaucracy. Bringing together a decade of ethnographic research in hospital wards, laboratories, and online patient discussion forums, Song opens up important theoretical and methodological horizons in the anthropology of science, technology, and medicine. She illuminates how poignant journeys in search of fetal cell cures become tangled in complex webs of digital mediation, the entrepreneurial logics of postsocialist medicine, and fraught debates about the ethics of clinical experimentation. Using innovative methods to track the border-crossing quests of Chinese clinicians and their patients from around the world, Biomedical Odysseys is the first book to map the transnational life of fetal cell therapies.

Regenerative Medicine & Peripheral Nerve Endoscopy

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9815274473
Total Pages : 214 pages
Book Rating : 4.8/5 (152 download)

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Book Synopsis Regenerative Medicine & Peripheral Nerve Endoscopy by : Kai-Uwe Lewandrowski, William Omar Contreras López, Jorge Felipe Ramírez León, Álvaro Dowling, Morgan P. Lorio

Download or read book Regenerative Medicine & Peripheral Nerve Endoscopy written by Kai-Uwe Lewandrowski, William Omar Contreras López, Jorge Felipe Ramírez León, Álvaro Dowling, Morgan P. Lorio and published by Bentham Science Publishers. This book was released on 2024-08-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendoscopy and Interventional Pain Medicine is a clinically focused medical monograph series. With contributions from a team of internationally recognized neurosurgeons and spinal surgery specialists, the series aims to illuminate the latest advancements in minimally invasive neurosurgical techniques and pain management. Each volume offers invaluable insights into the future of minimally invasive treatments in this medical subspecialty. Interventional Pain Surgery is the third of the monograph series. This book comprehensively covers endoscopic techniques for spinal surgery. Topics include interlaminar lumbar endoscopy, transforaminal lumbar discectomy, endoscopic approaches for lumbar spinal canal stenosis, and management of chronic low back pain through rhizotomy and rhiziolysis. The endoscopic treatment of basivertebral neuropathy, cervical foraminotomy, and decompression techniques is explained in dedicated chapters. Finally, the book also addresses endoscopic posterior lumbar interbody fusion and procedures for adjacent segment disease after lumbar fusion. Key Features - Covers a wide range of topics in neuroendoscopy and interventional pain medicine - Emphasizes evidence-based approaches to treatment - Offers clinical perspectives from expert surgeons - Includes scientific references for researchers and advanced learners It is an essential resource for readers who need to enhance their understanding of the latest technological advancements in neuroendoscopy and interventional pain medicine and apply these innovative techniques to improve patient outcomes.

Advances in Blood Transfusion Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 146499160X
Total Pages : 1246 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Advances in Blood Transfusion Research and Application: 2012 Edition by :

Download or read book Advances in Blood Transfusion Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 1246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Blood Transfusion Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Blood Transfusion. The editors have built Advances in Blood Transfusion Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Blood Transfusion in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Blood Transfusion Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The elephant and the dragon in contemporary life sciences

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Author :
Publisher : Manchester University Press
ISBN 13 : 1526159511
Total Pages : 118 pages
Book Rating : 4.5/5 (261 download)

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Book Synopsis The elephant and the dragon in contemporary life sciences by : Joy Y. Zhang

Download or read book The elephant and the dragon in contemporary life sciences written by Joy Y. Zhang and published by Manchester University Press. This book was released on 2022-03-15 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a powerful diagnosis of why the global governance of science struggles in the face of emerging powers. Through unpacking critical events in China and India over the past twenty years, it demonstrates that the ‘subversiveness’ assumed in the two countries’ rise in the life sciences reflects many of the regulatory challenges that are shared worldwide. It points to a decolonial imperative for science governance to be responsive and effective in a cosmopolitan world. By highlighting epistemic injustice within contemporary science, the book extends theories of decolonisation.

Neurorestoratology

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Author :
Publisher : Nova Science Publishers
ISBN 13 : 9781634636001
Total Pages : 0 pages
Book Rating : 4.6/5 (36 download)

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Book Synopsis Neurorestoratology by : Hongyun Huang

Download or read book Neurorestoratology written by Hongyun Huang and published by Nova Science Publishers. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurorestoratology is one of the most important disciplines in modern medicine and is also the most important discipline in neuroscience. Its core aim is to restore, promote and maintain the integrity of impaired or lost neuronal functions and/or structures by using novel cell-based comprehensive neurorestorative strategies. This book is the first and a unique one that systematically expounds the main aspects of neurorestoratology, which includes three sections with 22 chapters in two volumes. It systematically elaborates CNS neurorestorable theory and neurorestorative mechanisms. It firstly comprehends the Neurorestorative Process as a whole and Neurorestorative law. It fully describes all neurorestorative strategies and their continuing clinical progresses and achievements, especially the cell-based comprehensive neurorestorative strategies.

Topics in Anti-Cancer Research

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608059081
Total Pages : 668 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Topics in Anti-Cancer Research by : Atta-ur Rahman

Download or read book Topics in Anti-Cancer Research written by Atta-ur Rahman and published by Bentham Science Publishers. This book was released on 2014-11-28 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third volume of the Patent eBook Series entitled Topics in Anti-Cancer Research. This eBook comprises updated reviews on topics relevant to modern cancer research published in the journal Recent Patents on Anti-Cancer Drug Discovery. The comprehensive range of themes covered in this third volume will be of benefit to clinicians, scientists and R&D experts looking for new targets for the prevention of cancer and discovery of drugs for the treatment of different cancer types. Regulation of tumor cells by TRAIL receptors, development of anti- cancer drugs & immunomodulatory drugs, molecular studies of adrenocortical cancer, role of inhibitors of inosine monophosphate dehydrogenase in cancer, recent updates in glioblastoma stem cells, latest approaches for cancer gene therapy and metabolic therapy for cancer were reviewed and updated. The role of pH regulation and application of hyperthermia, thiosemicarbazone derivatives, tamoxifen-based therapies for cancer treatment andproteome-based complex therapy of tumors, calcium signaling and angiogenesis, antineoplastic role of GHRH antagonists and therapeutic applications in human tumors and clinical oncology have been extensively discussed in the light of recent innovations. The topics covered in this third volume will be valuable for those interested in scientists interests in methods for the prevention of cancer as well its management.

Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

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Author :
Publisher : Academic Press
ISBN 13 : 0128198362
Total Pages : 646 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma by : Michael Fehlings

Download or read book Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma written by Michael Fehlings and published by Academic Press. This book was released on 2022-02-17 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Cell and Gene Therapies for Neurologic Diseases

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Author :
Publisher : Elsevier
ISBN 13 : 0323901212
Total Pages : 342 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Cell and Gene Therapies for Neurologic Diseases by :

Download or read book Cell and Gene Therapies for Neurologic Diseases written by and published by Elsevier. This book was released on 2024-10-02 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson's, Huntington's, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs. - Summarizes advances in cell and gene therapy for neurological diseases - Describes the therapies available and in development - Includes surgical, ethical, and manufacturing considerations - Identifies best practices for specific neurological diseases - Covers Huntington's, Parkinson's, ALS, Stroke, Demyelination, epilepsy, and more

Biofabrication for Orthopedics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527831355
Total Pages : 792 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Biofabrication for Orthopedics by : Wenguo Cui

Download or read book Biofabrication for Orthopedics written by Wenguo Cui and published by John Wiley & Sons. This book was released on 2022-10-03 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofabrication for Orthopedics A comprehensive overview of biofabrication techniques for orthopedics and their novel applications With an ever-increasing global population and the rise in the occurrence of orthopedic diseases amongst an aging population, it is essential for technological advances to meet this growing medical need. Orthopedic biofabrication is a cutting-edge field that seeks to produce novel clinical solutions to this mounting problem, through the incorporation of revolutionary technologies that have the potential to not only transform healthcare, but also provide highly automated and personalized patient solutions. With the advances in the discipline, there is a significant growing interest in biofabrication for orthopedics in research activity geared towards routine clinical use. Ideal for a broad readership amongst medical practitioners and scientists, Biofabrication for Orthopedics summarizes all aspects of the topic: detailed information on the technology, along with advanced developments, research progress, and future perspectives on biofabrication for orthopaedics—particularly on the potential applications for tissue engineering technologies. In doing so, the book describes the various biomaterials—natural and synthetic—use for orthopedics and discusses the many ways in which these materials can be used in all parts of the body. As such, it offers detailed information on a wide range of applications in the fields of biology and clinical and industrial manufacturing. Biofabrication for Orthopedics readers will also find: Insights into the applications of biofabrication technologies in various bodily functions Thorough discussion of different biofabrication techniques used in creating orthopedic products, like stereolithography, cell sheet and organ bioprinting, electrospinning, and microfluidics Discussion of a wide range of diverse functions, such as bone implants, skin regeneration, vascularization, meniscus remodeling, and more Biofabrication for Orthopedics is a useful reference for those in a variety of research fields like medical-related practitioners and scientists, materials science, medicine, and manufacturing, as well as the libraries who support them.

Current Challenges in Cell Therapy for Neurodegenerative Diseases

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Author :
Publisher : Academic Press
ISBN 13 : 0323989381
Total Pages : 326 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Current Challenges in Cell Therapy for Neurodegenerative Diseases by :

Download or read book Current Challenges in Cell Therapy for Neurodegenerative Diseases written by and published by Academic Press. This book was released on 2022-11-22 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington's disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington's Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more. Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson's and Huntington's disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in International Review on Neurobiology serials - Updated release includes the latest information on Cell Transplantation and Gene Therapy in Neurodegenerative Disease

Therapeutic Strategies to Spinal Cord Injury

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Author :
Publisher : MDPI
ISBN 13 : 3038974064
Total Pages : 239 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Therapeutic Strategies to Spinal Cord Injury by : Pavla Jendelova

Download or read book Therapeutic Strategies to Spinal Cord Injury written by Pavla Jendelova and published by MDPI. This book was released on 2018-11-29 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Therapeutic Strategies to Spinal Cord Injury" that was published in IJMS

Psychopharmacology Algorithms

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975151216
Total Pages : 384 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Psychopharmacology Algorithms by : David Osser

Download or read book Psychopharmacology Algorithms written by David Osser and published by Lippincott Williams & Wilkins. This book was released on 2020-09-22 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algorithms serve an important purpose in the field of psychopharmacology as heuristics for avoiding the biases and cognitive lapses that are common when prescribing for many conditions whose treatment is based on complex data. Unique in the field, this title compiles twelve papers from the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program and presents practical ways to adopt evidence-based practices into the day-to-day treatment of patients. Psychopharmacology Algorithms is a useful resource for practicing psychiatrists, residents, and fellows, as well as psychiatric nurse practitioners, psychiatric physician assistants who prescribe, advanced practice pharmacists who prescribe, and primary care clinicians. Teachers of psychopharmacology may find it particularly valuable. Researchers in clinical psychopharmacology may find it helpful in identifying important practice areas that are in need of further study.

Behavioural Phenotypes

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9781898683063
Total Pages : 236 pages
Book Rating : 4.6/5 (83 download)

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Book Synopsis Behavioural Phenotypes by : Gregory O'Brien

Download or read book Behavioural Phenotypes written by Gregory O'Brien and published by Cambridge University Press. This book was released on 1995 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing interest over recent years in the study of the influences of environment and genetic factors on behavioural disorder has come from a wide range of disciplines. These studies have subsequently been focused through the foundation of the Society for the Study of Behavioural Phenotypes, which forms the basis for assimilating new information and coordinating future research in this field. This volume from founder members of the society presents a distillation of thinking and reviews appropriate measurement schedules. Including research findings, explanation of concepts, genetic scientific techniques and methodological issues, this work will be welcomed by those with an interest in behavioural disorder at every level.