Integrated CMOS-based Biochemical Sensor Microsystems

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (697 download)

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Book Synopsis Integrated CMOS-based Biochemical Sensor Microsystems by : Lei Yao

Download or read book Integrated CMOS-based Biochemical Sensor Microsystems written by Lei Yao and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrated CMOS Sensor Microsystems for Biochemical Monitoring

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Publisher :
ISBN 13 :
Total Pages : 188 pages
Book Rating : 4.:/5 (848 download)

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Book Synopsis Integrated CMOS Sensor Microsystems for Biochemical Monitoring by :

Download or read book Integrated CMOS Sensor Microsystems for Biochemical Monitoring written by and published by . This book was released on 2006 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complementary metal-oxide semiconductor (CMOS) based sensor systems play an important role in various medical, biotechnological, industrial, food and beverage, security and defense, and environmental applications. This is primarily because standard CMOS fabrication processes allow us to produce low cost, low power, and miniaturized systems which can be easily mass-produced. This dissertation deals with the development of integrated CMOS optical based and CMOS solid-state based sensor microsystems for monitoring various analytes including oxygen (O 2), glucose, solvents, and pH. The optical sensors developed as part of this dissertation are based on phase fluorometric measurement techniques and use sol-gel derived xerogel based sensing elements to encapsulate analyte specific fluorophores in nanoscopic porous structures. The majority of the research efforts have concentrated on the development of ultrahigh sensitivity photodetectors and the subsequent conversion of the current signals into voltage signals for easy processing. Finally, these contributions have led to the first demonstration of a single-chip CMOS integrated circuit with monolithically integrating detectors and signal processing for phase fluorometric sensor systems. The solid-state sensors developed as part of this dissertation are based on CMOS ion-sensing field effect transistors (ISFET). We concentrated on the development of the ISFET readout circuitry and ISFET layout architecture which would improve the performance and the reliability of the pH-sensitive microsystems for various biomedical applications. We proposed a novel differential read-out architecture which uses a pseudo-reference electrode (gold wire) and overcomes the requirement of an ideal reference electrode (Ag/AgCl or calomel electrodes) for applications where measuring changes in pH is sufficient. Finally, using this architecture enables the CMOS ISFET microsystem to be fabricated using a standard CMOS process without any post-fabrication processing. In the future, based on the principles described here, the integration of CMOS devices with various emerging sensing elements such as surface activated nanoparticles, porous materials, and imprinted sensing layers can lead to the development of novel sense and response systems with high sensitivity, selectivity and dynamic range.

Integrated Chemical Microsensor Systems in CMOS Technology

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Publisher : Springer Science & Business Media
ISBN 13 : 3540273727
Total Pages : 236 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Integrated Chemical Microsensor Systems in CMOS Technology by : Andreas Hierlemann

Download or read book Integrated Chemical Microsensor Systems in CMOS Technology written by Andreas Hierlemann and published by Springer Science & Business Media. This book was released on 2005-08-29 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with a comprehensive survey of existing semiconductor-based chemical microsensors and microsystems, this book proceeds to describe in detail CMOS technology-based chemical microsensor systems. The benefits of using CMOS technology for developing chemical microsensor systems and, in particular, monolithically integrated sensor systems comprising transducers and associated circuitry are laid out. Several successful realizations of such microsensor systems are presented. First, the fundamentals of the chemical sensing process itself will be elucidated, followed by a short description of microfabrication techniques and the CMOS substrate. Thereafter, a comprehensive overview of semiconductor-based and CMOS-based transducer structures and their applications is given. It is shown that CMOS-technology can be successfully used as platform technology to integrate microtransducers with the necessary driving and signal conditioning circuitry, and, in a next step, to develop monolithic multisensor arrays and fully developed microsystems with on-chip sensor control and standard interfaces. The book concludes with a brief outlook to future developments, such as interfacing cells with CMOS microelectronics.

CMOS Contact and Phase Imaging of Biochemical Sensor Microarray

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (922 download)

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Book Synopsis CMOS Contact and Phase Imaging of Biochemical Sensor Microarray by : Daisy Daivasagaya

Download or read book CMOS Contact and Phase Imaging of Biochemical Sensor Microarray written by Daisy Daivasagaya and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "In this Thesis, we present two systems for gaseous oxygen (O2) sensing. First, we describe a compact luminescent sensor microsystem that is based on the direct integration of sensor elements with a polymeric optical filter and placed on a low power Complementary Metal-Oxide Semiconductor (CMOS) imager Integrated Circuit (IC). The second system is a hand-held scale phase fluorometric system. This system is based on a new single-chip integrated circuit that can perform the activities of sinusoidal signal generation using Direct Digital Synthesis and phase angle extraction of the detection luminescence signal from the sensor films using Discrete Fourier Transform. For O2 sensing, the sensors operate on the measurement of excited-state emission intensity of O2-sensitive luminophores tris(4,7-diphenyl-1,10- phenanthroline) ruthenium(II) ([Ru(dpp)3]2+) encapsulated in sol-gel derived xerogel thin-films. For the compact luminescent sensor microsystem, we incorporate a polymeric optical filter that is made with polydimethylsiloxane (PDMS) that is mixed with color die Sudan-II. The surface of the PDMS filter is molded to incorporate arrays of pyramidal microstructures that serve to focus the optical sensor signals on to the photodetectors. The xerogel sensor arrays are contact printed on top of the PDMS pyramidal lens-like microstructures. The CMOS imager uses a 32x32 (1024 elements) array of active pixel sensors and each pixel includes a high-gain phototransistor to convert the detected optical signals into electrical currents. Correlated double sampling circuit, pixel address, digital control and signal integration circuits are also implemented on-chip. The CMOS imager data is read out as a serial coded signal. The developed CMOS sensor microsystems provide a useful platform for the development of miniaturized, analytically reliable, and accurate optical chemical gaseous and aqueous sensors." --

CMOS Biomicrosystems

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Publisher : John Wiley & Sons
ISBN 13 : 1118016483
Total Pages : 425 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis CMOS Biomicrosystems by : Krzysztof Iniewski

Download or read book CMOS Biomicrosystems written by Krzysztof Iniewski and published by John Wiley & Sons. This book was released on 2011-10-14 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will address the-state-of-the-art in integrated Bio-Microsystems that integrate microelectronics with fluidics, photonics, and mechanics. New exciting opportunities in emerging applications that will take system performance beyond offered by traditional CMOS based circuits are discussed in detail. The book is a must for anyone serious about microelectronics integration possibilities for future technologies. The book is written by top notch international experts in industry and academia. The intended audience is practicing engineers with electronics background that want to learn about integrated microsystems. The book will be also used as a recommended reading and supplementary material in graduate course curriculum.

Microsystems and Nanotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642182933
Total Pages : 1011 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Microsystems and Nanotechnology by : Zhaoying Zhou

Download or read book Microsystems and Nanotechnology written by Zhaoying Zhou and published by Springer Science & Business Media. This book was released on 2012-08-30 with total page 1011 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Microsystems and Nanotechnology” presents the latest science and engineering research and achievements in the fields of microsystems and nanotechnology, bringing together contributions by authoritative experts from the United States, Germany, Great Britain, Japan and China to discuss the latest advances in microelectromechanical systems (MEMS) technology and micro/nanotechnology. The book is divided into five parts – the fundamentals of microsystems and nanotechnology, microsystems technology, nanotechnology, application issues, and the developments and prospects – and is a valuable reference for students, teachers and engineers working with the involved technologies. Professor Zhaoying Zhou is a professor at the Department of Precision Instruments & Mechanology , Tsinghua University , and the Chairman of the MEMS & NEMS Society of China. Dr. Zhonglin Wang is the Director of the Center for Nanostructure Characterization, Georgia Tech, USA. Dr. Liwei Lin is a Professor at the Department of Mechanical Engineering, University of California at Berkeley, USA.

CMOS - MEMS

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Publisher : John Wiley & Sons
ISBN 13 : 352767506X
Total Pages : 610 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis CMOS - MEMS by : Henry Baltes

Download or read book CMOS - MEMS written by Henry Baltes and published by John Wiley & Sons. This book was released on 2013-03-26 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition of 'CMOS-MEMS' was originally published in the successful series 'Advanced Micro & Nanosystems'. Here, the combination of the globally established, billion dollar chip mass fabrication technology CMOS with the fascinating and commercially promising new world of MEMS is covered from all angles. The book introduces readers to this fi eld and takes them from fabrication technologies and material charaterization aspects to the actual applications of CMOS-MEMS - a wide range of miniaturized physical, chemical and biological sensors and RF systems. Vital knowledge on circuit and system integration issues concludes this in-depth treatise, illustrating the advantages of combining CMOS and MEMS in the first place, rather than having a hybrid solution.

Integrated Chemical Microsensor Systems in CMOS Technology

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540237822
Total Pages : 248 pages
Book Rating : 4.2/5 (378 download)

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Book Synopsis Integrated Chemical Microsensor Systems in CMOS Technology by : Andreas Hierlemann

Download or read book Integrated Chemical Microsensor Systems in CMOS Technology written by Andreas Hierlemann and published by Springer Science & Business Media. This book was released on 2005-02-21 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, "Integrated Chemical Microsensor Systems in CMOS Technology", provides a comprehensive treatment of the highly interdisciplinary field of CMOS chemical microsensor systems. It is targeted at students, scientists and engineers who are interested in gaining an introduction to the field of chemical sensing since all the necessary fundamental knowledge is included. However, as it provides detailed information on all important issues related to the realization of chemical microsensors in CMOS technology, it also addresses experts well familiar with the field. After a brief introduction, the fundamentals of chemical sensing are presented. Fabrication and processing steps that are commonly used in the semiconductor industry are then detailed followed by a short description of the microfabrication techniques, and of the CMOS substrate and materials. Thereafter, a comprehensive overview of semiconductor-based and CMOS-based transducer structures for chemical sensors is given. CMOS-technology is then introduced as platform technology, which enables the integration of these microtransducers with the necessary driving and signal conditioning circuitry on the same chip. In a next section, the development of monolithic multisensor arrays and fully developed microsystems with on-chip sensor control and standard interfaces is described. A short section on packaging shows that techniques from the semiconductor industry can be applied to chemical microsensor packaging. The book concludes with a brief outlook on future developments, such as the realization of more complex integrated microsensor systems and methods to interface biological materials, such as cells, with CMOS microelectronics.

Cmos-Based Sensors and Actuators for Life Science Applications

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Publisher : IET
ISBN 13 : 183953673X
Total Pages : 609 pages
Book Rating : 4.8/5 (395 download)

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Book Synopsis Cmos-Based Sensors and Actuators for Life Science Applications by : Ebrahim Ghafar-Zadeh

Download or read book Cmos-Based Sensors and Actuators for Life Science Applications written by Ebrahim Ghafar-Zadeh and published by IET. This book was released on 2024-01-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: CMOS technologies and their ongoing downscaling trend have opened an avenue to developing integrated systems for life sciences. This book explores the theoretical and practical aspects of CMOS biosensors and discusses the fundamentals of biological applications and microfabrication.

Integrated Microsystems

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Publisher : CRC Press
ISBN 13 : 1439836213
Total Pages : 760 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Integrated Microsystems by : Krzysztof Iniewski

Download or read book Integrated Microsystems written by Krzysztof Iniewski and published by CRC Press. This book was released on 2017-12-19 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia and industry around the world, this reference covers processes compatible with CMOS integrated circuits, which combine computation, communications, sensing, and actuation capabilities. Light on math and physics, with a greater emphasis on microsystem design and configuration and electrical engineering, this book is organized in three sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key topics, including physical and chemical sensing, imaging, smart actuation, and data fusion and management. Using tables, figures, and equations to help illustrate concepts, contributors examine and explain the potential of emerging applications for areas including biology, nanotechnology, micro-electromechanical systems (MEMS), microfluidics, and photonics.

CMOS Integrated Lab-on-a-chip System for Personalized Biomedical Diagnosis

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Publisher : John Wiley & Sons
ISBN 13 : 1119218357
Total Pages : 290 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis CMOS Integrated Lab-on-a-chip System for Personalized Biomedical Diagnosis by : Hao Yu

Download or read book CMOS Integrated Lab-on-a-chip System for Personalized Biomedical Diagnosis written by Hao Yu and published by John Wiley & Sons. This book was released on 2018-04-04 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough examination of lab-on-a-chip circuit-level operations to improve system performance A rapidly aging population demands rapid, cost-effective, flexible, personalized diagnostics. Existing systems tend to fall short in one or more capacities, making the development of alternatives a priority. CMOS Integrated Lab-on-a-Chip System for Personalized Biomedical Diagnosis provides insight toward the solution, with a comprehensive, multidisciplinary reference to the next wave of personalized medicine technology. A standard complementary metal oxide semiconductor (CMOS) fabrication technology allows mass-production of large-array, miniaturized CMOS-integrated sensors from multi-modal domains with smart on-chip processing capability. This book provides an in-depth examination of the design and mechanics considerations that make this technology a promising platform for microfluidics, micro-electro-mechanical systems, electronics, and electromagnetics. From CMOS fundamentals to end-user applications, all aspects of CMOS sensors are covered, with frequent diagrams and illustrations that clarify complex structures and processes. Detailed yet concise, and designed to help students and engineers develop smaller, cheaper, smarter lab-on-a-chip systems, this invaluable reference: Provides clarity and insight on the design of lab-on-a-chip personalized biomedical sensors and systems Features concise analyses of the integration of microfluidics and micro-electro-mechanical systems Highlights the use of compressive sensing, super-resolution, and machine learning through the use of smart SoC processing Discusses recent advances in complementary metal oxide semiconductor-integrated lab-on-a-chip systems Includes guidance on DNA sequencing and cell counting applications using dual-mode chemical/optical and energy harvesting sensors The conventional reliance on the microscope, flow cytometry, and DNA sequencing leaves diagnosticians tied to bulky, expensive equipment with a central problem of scale. Lab-on-a-chip technology eliminates these constraints while improving accuracy and flexibility, ushering in a new era of medicine. This book is an essential reference for students, researchers, and engineers working in diagnostic circuitry and microsystems.

Chemical Sensors 7 -and- MEMS/NEMS 7

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Publisher : The Electrochemical Society
ISBN 13 : 1566775108
Total Pages : 517 pages
Book Rating : 4.5/5 (667 download)

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Book Synopsis Chemical Sensors 7 -and- MEMS/NEMS 7 by : Peter J. Hesketh

Download or read book Chemical Sensors 7 -and- MEMS/NEMS 7 written by Peter J. Hesketh and published by The Electrochemical Society. This book was released on 2006 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest developments in chemical and biological sensor research and development. Topics include: 1. new selective species recognition surfaces and materials; 2. molecular recognition materials and approaches to minimize non-specific binding; 3. semi-selective species recognition materials; 4. novel methods for signal processing, signal amplification, and detection; 5. detection systems for multiple analytes in complex samples; 6. sensor arrays; and 7. analytical systems and approaches.

CMOS Biotechnology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387689133
Total Pages : 394 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis CMOS Biotechnology by : Hakho Lee

Download or read book CMOS Biotechnology written by Hakho Lee and published by Springer Science & Business Media. This book was released on 2007-05-04 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lately, there has been a growing interest in exploiting the benefits of the ICs for areas outside of the traditional application spaces. One noteable area is found in biology Bioanalytical instruments have been miniaturized on ICs to study various biophenomena or to actuate biosystems. These biolab-on-IC systems utilize the IC to facilitate faster, repeatable, and standardized biological experiments at low cost with a small volume of biological sample. The research activities in this field are expected to enjoy substantial growth in the foreseeable future. BioCMOS Technologies reviews these exciting recent efforts in joining CMOS technology with biology.

CMOS Circuits for Biological Sensing and Processing

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Publisher : Springer
ISBN 13 : 3319677233
Total Pages : 354 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis CMOS Circuits for Biological Sensing and Processing by : Srinjoy Mitra

Download or read book CMOS Circuits for Biological Sensing and Processing written by Srinjoy Mitra and published by Springer. This book was released on 2017-11-18 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most comprehensive and consistent survey of the field of IC design for Biological Sensing and Processing. The authors describe a multitude of applications that require custom CMOS IC design and highlight the techniques in analog and mixed-signal circuit design that potentially can cross boundaries and benefit the very wide community of bio-medical engineers.

Sensors and Microsystems

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Publisher : Springer Science & Business Media
ISBN 13 : 9048136067
Total Pages : 435 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Sensors and Microsystems by : Piero Malcovati

Download or read book Sensors and Microsystems written by Piero Malcovati and published by Springer Science & Business Media. This book was released on 2010-03-14 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sensors and Microsystems contains a selection of papers presented at the 14th Italian conference on sensors and microsystems. It provides a unique perspective on the research and development of sensors, microsystems and related technologies in Italy. The scientific values of the papers also offers an invaluable source to analyists intending to survey the Italian situation about sensors and microsystems. In an interdisciplinary approachm many aspects of the disciplines are covered, ranging from materials science, chemistry, applied physics, electronic engineering and biotechnologies. Further details of the conference and its full program at the website http://www.microelectronicsevents.com/AISEM

Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems

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Publisher : Springer Science & Business Media
ISBN 13 : 0387751130
Total Pages : 980 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems by : Mohammed Zourob

Download or read book Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems written by Mohammed Zourob and published by Springer Science & Business Media. This book was released on 2008-09-03 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems will cover the up-to-date biosensor technologies used for the detection of bacteria. Written by the world's most renowned and learned scientists each in their own area of expertise, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems is the first title to cover this expanding research field.

Sensors and Microsystems

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Publisher : Springer Nature
ISBN 13 : 3031257065
Total Pages : 211 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Sensors and Microsystems by : Girolamo Di Francia

Download or read book Sensors and Microsystems written by Girolamo Di Francia and published by Springer Nature. This book was released on 2023-02-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book showcases the state of the art in the field of sensors and microsystems, revealing the impressive potential of novel methodologies and technologies. It covers a broad range of aspects, including: bio-, physical and chemical sensors; actuators; micro- and nano-structured materials; mechanisms of interaction and signal transduction; polymers and biomaterials; sensor electronics and instrumentation; analytical microsystems, recognition systems and signal analysis; and sensor networks, as well as manufacturing technologies, environmental, food and biomedical applications. The book gathers a selection of papers presented at the 21st AISEM National Conference on Sensors and Microsystems, held in Rome, Italy, in February 2022, which brought together researchers, end users, technology teams and policymakers.