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Insulin Like Growth Factors Somatomedins
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Book Synopsis Insulin - Like Growth Factors. Somatomedins by : E. Martin Spencer
Download or read book Insulin - Like Growth Factors. Somatomedins written by E. Martin Spencer and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-11-18 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keine ausführliche Beschreibung für "Insulin - Like Growth Factors. Somatomedins" verfügbar.
Book Synopsis Insulin-like Growth Factors, Somatomedins by : E. Martin Spencer
Download or read book Insulin-like Growth Factors, Somatomedins written by E. Martin Spencer and published by . This book was released on 1983 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Barrett's Esophagus and Esophageal Adenocarcinoma by : Prateek Sharma
Download or read book Barrett's Esophagus and Esophageal Adenocarcinoma written by Prateek Sharma and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference text entirely devoted to this increasinglysignificant condition This text is dedicated to Barrett’s esophagus and providesrecent evidence and current approaches to patient management. Ithas been completely revised, updated and extended to include thelatest research findings and describes how these affect day-to-dayclinical practice. It includes seven new chapters and even more color images thanthe last edition. Each chapter, written by the leadinginternational experts in the field, provides clear, didacticguidance on diagnosis, treatment and management of thiscondition. Barrett’s Espohagus gives an extensive overviewcovering epidemiology, screening, pathology, gastroenterology andsurgery. It looks at the precursor lesions leading to thedevelopment of Barrett’s epithelium, the uniquecharacteristics of Barrett’s esophagus, and the consequencesof malignant degeneration. All aspects of diagnosis, secondaryprevention, multimodality, and medical and surgical treatment areclearly explained. This is a complete guide on the latest thinking on diagnosis andtreatment of Barrett’s esophagus which can be referred toover and over again.
Book Synopsis Designing Foods by : National Research Council
Download or read book Designing Foods written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This lively book examines recent trends in animal product consumption and diet; reviews industry efforts, policies, and programs aimed at improving the nutritional attributes of animal products; and offers suggestions for further research. In addition, the volume reviews dietary and health recommendations from major health organizations and notes specific target levels for nutrients.
Book Synopsis Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors by : Derek LeRoith
Download or read book Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors written by Derek LeRoith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume addresses a fundamental puzzle in biology and medicine, namely, how does tissue develop, repair and replace itself. The answer appears to lie in growth factors and their regulation. To thrive and survive we need growth factors and this book concentrates on two factors that are related to growth hormone. Growth hormone does not act directly on all tissues, but mediates many of its actions through the release of insulin-like growth factors from the liver. The growth factors were originally called somatomedins by McConaghey and Sledge (1), who discovered that they mediated growth-like effects of growth hormone. However, the factors were purified on the basis of their insulinomimetic actions on fat and muscle and it is their relationship to the insulin family of pep tides that now gives them their name (2,3) of insulin-like growth factors (IGFs). They mediate the actions of. growth hormone on the proteoglycan synthesis of cartilage and produce mitogenic effects in fibroblast cultures.
Book Synopsis Insulin-like Growth Factors by : Derek LeRoith
Download or read book Insulin-like Growth Factors written by Derek LeRoith and published by CRC Press. This book was released on 1991-05-28 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, the continued interest in insulin-related growth factors has been documented by a plethora of research programs and publications focused on these growth factors. Both molecular and cellular biological techniques have improved and enabled investigators to study the properties of the growth factors in depth. This volume covers the molecular (genetic) aspects of the growth factors, their binding proteins and receptors, as well as those factors affecting their gene transcription and translation. In addition, aspects of the cellular action of these growth factors through their receptors and how this impacts normal cellular function are discussed. The book will provide valuable information for researchers in physiology, biology, endocrinology, and metabolism.
Book Synopsis Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy by : G V Sherbet
Download or read book Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy written by G V Sherbet and published by Elsevier. This book was released on 2011-07-14 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation G.V. Sherbet provides insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. The book focuses on the relationships and convergence of growth factors and their receptors in development and pathogenesis.
Book Synopsis Growth Hormone and Somatomedins during Lifespan by : Eugenio E. Müller
Download or read book Growth Hormone and Somatomedins during Lifespan written by Eugenio E. Müller and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The various congresses on growth hormone (GH) which have been held in Milan since 1967, the Milan Congresses, have witnessed over 25 years the tremendous expansion of a research field that was based initially upon the scarce knowledge of the biological properties of a protein. GH, whose chemical structure had just been identified and a radioimmunoassay developed for its measurement in blood, became in the following years a major area of biological research. The boundaries have since become blurred, as the research area has extended to the physiology and pathology of growth, puberty and reproduction, and the control of metabolism during the whole lifespan. Since the last GH Congress held in 1987, GH studies using the molecular biological approach have resulted in the puri fication, cloning and expression of the human GH (hGH) recep tor and binding protein, in new and exciting information on the insulin-like growth factors (IGF) and their paracrine and autocrine roles, and in the awareness that a panoply of binding proteins are present in the extracellular fluids and can, possibly, modulate IGF-receptor interactions and, thus, IGF actions. Finally, the availability of large amounts of biosynthetic hGH, besides allow ing more extensive clinical use in states of GH deficiency and extrasomatotrophic pathologies, has permitted disclosure of im portant metabolic effects of hGH during adulthood and, perhaps, aging and in many protein catabolic states.
Book Synopsis The Physiology of Human Growth by : James Mourilyan Tanner
Download or read book The Physiology of Human Growth written by James Mourilyan Tanner and published by Cambridge University Press. This book was released on 1989-06-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers a wide spectrum of growth physiology, and presents a state-of-the-art review of human auxology.
Book Synopsis Modern Concepts of Insulin-like Growth Factors by : E. Martin Spencer
Download or read book Modern Concepts of Insulin-like Growth Factors written by E. Martin Spencer and published by Elsevier Publishing Company. This book was released on 1991 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: To address the explosion of new and exciting information on the insulin-like growth factors (IGFs), the Second International Symposium on Insulin-Like Growth Factors/Somatomedins was convened from January 12-16, 1991, in San Francisco, California. This book covers many diverse research areas, fostering communication among specialists from such areas as growth and development, cell physiology, reproductive physiology, nephrology, surgery, molecular genetics, oncology and ophthalmology. More than 45 renowned experts present comprehensive discussions of the major areas of IGF research, reviewing the significant background information, presenting the latest in IGF research, and also recommending nomenclature of IGF genes, transcripts, and binding proteins drawn up by special panels.These recurrent themes are expressed throughout: # The remarkable ability of IGFs to adapt, to acquire new functions in different organ systems, and to facilitate actions of other tropic hormones # Autocrine and Paracrine modes of action # The critical role of the IGF binding proteins in regulating IGF actions and delivery to and from tissue # The unique heterogeneity of IGF mRNAs that potentially offers multiple mechanisms for differential regulation of IGF gene expression.
Download or read book Acromegaly written by Richard J. Robbins and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The manuscripts in this volume were contributed by the speakers invited to the Acromegaly Centennial Symposium held in San Francisco, California in July 1986. The meeting was organized to commemorate the description of acromegaly by the French physician Pierre Marie, in 1886. The members of the Scientific Committee spent many hours assisting us in ensuring an outstanding meeting. The support of Serono Symposia, USA in all phases of the planning and execution of the meeting was sincerely appreciated and was highly professional. Special recognition roust be extended to Professor Roger Guillemin of the Salk Institute, whosp interest in medical history led him to devote a great deal of time and personal expense in obtaining information about the life of Pierre Marie. Dr. GuilIemin's presentation on the life and times of Marie was an extraordinary overview of the cultural, social, and scientific backgrounds in which Marie came to describe the disease, acromegaly. Dr. Guillemin' s findings, which were presented at the main banquet in a splendid audiovisual presentation, were clearly the highlight of the meeting and will long be remembered by the attendees. We were also honored by the presence of Dr. Martine Pierre Marie Granier, the great-granddaughter of Pierre Harie. In her address at the banquet, Dr. Granier provided several delightful and intimate vignettes concerning Pierre Marie, using old family records and photographs. The Scientific Committee wishes to extend its gratitude to Dr. Granier for adding immeasurably to the historical atmosphere of the meeting.
Book Synopsis Basic and Applied Bone Biology by : David B. Burr
Download or read book Basic and Applied Bone Biology written by David B. Burr and published by Academic Press. This book was released on 2013-06-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. Presents an in-depth overview of skeletal biology from the molecular to the organ level Offers "refresher" level content for clinicians or researchers outside their areas of expertise Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology
Book Synopsis Basic Aspects and Clinical Significance of the Insulin-like Growth Factors, Somatomedins by : E. Weimann
Download or read book Basic Aspects and Clinical Significance of the Insulin-like Growth Factors, Somatomedins written by E. Weimann and published by . This book was released on 1990 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Growth Hormone/Insulin-Like Growth Factor Axis during Development by : Isabel Varela-Nieto
Download or read book The Growth Hormone/Insulin-Like Growth Factor Axis during Development written by Isabel Varela-Nieto and published by Springer Science & Business Media. This book was released on 2005-12-17 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.
Book Synopsis Current Directions in Insulin-Like Growth Factor Research by : Derek LeRoith
Download or read book Current Directions in Insulin-Like Growth Factor Research written by Derek LeRoith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of the insulin-like growth factor (IGF) family has become an exciting area of investigation. Initially, this family consisted of ligands (insulin, IGF-I and IGF-m and receptors (the insulin receptor, the type I or IGF-I receptor and the type II or IGF-IYM-6-P receptor). Subsequently, it was discovered that six specific binding proteips (lGFBPs 1-6) playa major role in the actions of this growth factor family. In addition, there are now more potential receptors when one considers the possible roles of the insulin-receptor related receptor (IRR) and hybrid receptor dimers composed of insulin and IGF-I receptor (half-receptors). Another important aspect of this area of research is the realization that the IGFs are not only essential for normal growth and development but, in addition play an important role in the normal specialized function(s) of all tissues of the body, including the nervous system, skeleton, reproductive system, kidney, and the immune system, to name but a few. The development of recombi!tant human IGF-I for clinical testing has been a major breakthrough for investigators. Potential uses include wound healing, reversal of catabolic states, diabetes, bone remodeling, recovery from acute renal failure and many others. will determine both its use and its potential hazards.
Book Synopsis Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System by : Mohan Raizada
Download or read book Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System written by Mohan Raizada and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, intercellular communication and the regulation of biological functions of the body have been considered the role of two major and distinct systems: the nervous system and the endocrine system. The classic nervous system transmitted its signal rapidly by using electrical currents, whereas the signals used by the endocrine system were hormones produced by endocrine glands which reached the target tissues via the blood stream. During the past few decades, it has become apparent that these systems of intercellular com munication are not distinct and the signal messenger molecules are not unique to one or the other system. Many classic endocrine hormones are found in and act on nervous tissues and evidence exists for their de novo synthesis by neural related tissues. An exciting development in this area is the possibility that insulin and insulin-like growth factors (IGF) are not only produced by neural tissues but also exert profound physiological and biochemical effects on these tissues. The area of investigation of CNS insulin and IGF has been expanding rapidly and the availability of this book complete with up-to-date reviews on the subject by leaders in the field allows other scientists to utilize the knowledge in planning and adapting the latest ideas for future experiments. In addition, the book provides a collection of up-to-date articles for teachers to be used for the latest instructional material. The first section of the book covers general aspects of insulin receptors and insulin action.
Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.
Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
