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Author : Annalisa Pastore
Publisher : Frontiers Media SA
ISBN 13 : 2832505716
Total Pages : 126 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in Structural Biology: 2021 written by Annalisa Pastore and published by Frontiers Media SA. This book was released on 2022-11-15 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Thomas A Steitz
Publisher : World Scientific
ISBN 13 : 9811215871
Total Pages : 640 pages
Book Rating : 4.8/5 (112 download)
Download or read book Structural Insights Into Gene Expression And Protein Synthesis written by Thomas A Steitz and published by World Scientific. This book was released on 2020-08-18 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several years ago, Thomas Steitz agreed to contribute a volume to the 'World Scientific Series in Structural Biology' that would deal with the contributions he and his coworkers have made to structural biology during his remarkable career. Sadly, Tom died in the fall of 2018 before he had had time to do more than produce an outline for this book, and a list of the reprints he wanted it to contain.Fortunately, Tom's colleagues and coworkers responded enthusiastically when they were informed later that fall that if they were willing to help out, a volume would be published to commemorate his career. It fell to Anders Liljas, Peggy Eatherton, Tom's longtime administrative assistant, and Peter Moore, a close colleague, to oversee their efforts. Thomas Steitz is best known for the work he and his coworkers did to elucidate the biochemical basis of gene expression. The structures of a large number of the macromolecules involved in transcription and translation emerged from his laboratory over the course of his career. This book includes reprints of the most important papers he had published, grouped according to the structures they relate to, and commentaries written by the scientists who collaborated with him to solve each of them. It thus summarizes the achievements of one of the most distinguished biochemists of the second half of the 20th century.
Author :
Publisher : Academic Press
ISBN 13 : 032385320X
Total Pages : 382 pages
Book Rating : 4.3/5 (238 download)
Download or read book Proteomics and Systems Biology written by and published by Academic Press. This book was released on 2021-07-30 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics and Systems Biology, Volume 127 in the Advances in Protein Chemistry and Structural Biology series, outlines current proteomic methodologies and discuss the challenges in future applications of systems biology in a number of biomedical/bioscience subjects. In last few decades, advances in genomics, proteomics, metabolomics, glycomics, venomics, etc., have produced vast large-scale datasets that need to be analyzed with a single main objective of understanding biological systems as a whole. Such understanding will allow us to predict and characterize the dynamic properties of biological systems. Integrates experimental and computational methods for understanding biological systems as a whole Contains timely chapters written by well-renowned authorities in their field Includes well supported content that is accompanied by a number of high-quality illustrations, figures and tables, hence it targets a wide audience of specialists, researchers and students
Author : Simon Gilroy
Publisher : Frontiers Media SA
ISBN 13 : 2832502733
Total Pages : 176 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in Plant Cell Biology: 2021 written by Simon Gilroy and published by Frontiers Media SA. This book was released on 2022-10-18 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jean Marie François
Publisher : Frontiers Media SA
ISBN 13 : 283252270X
Total Pages : 194 pages
Book Rating : 4.8/5 (325 download)
Download or read book Insights in synthetic biology 2021: Novel developments, current challenges, and future perspectives written by Jean Marie François and published by Frontiers Media SA. This book was released on 2023-05-05 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : S.K. Malhotra
Publisher : Elsevier
ISBN 13 : 0080526500
Total Pages : 273 pages
Book Rating : 4.0/5 (85 download)
Download or read book Advances in Structural Biology written by S.K. Malhotra and published by Elsevier. This book was released on 1996-06-21 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume continues the trend established in previous volumes in this series on Advances in Structural Biology. As in the past, diverse topics of current importance relevant to the theme of the series are included in the fourth volume.
Author : Krishnarao Appasani
Publisher : CRC Press
ISBN 13 : 1040118844
Total Pages : 488 pages
Book Rating : 4.0/5 (41 download)
Download or read book Cryo-Electron Microscopy in Structural Biology written by Krishnarao Appasani and published by CRC Press. This book was released on 2024-10-17 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cryo-electron microscopy, in combination with tomography, has emerged as a new technology for visualizing molecular structures at a resolution beyond even 1 Å. Using this technology has revealed the native molecular details of viruses, membranes, enzymes, ribosomes, and cells. This comprehensive volume brings together authoritative overviews of these methods from structural and biological perspectives. It is a must-have for researchers and graduate students, as well as those working in industry, primarily in the areas of biophysics, structural biology, crystallography, and genomics. Key Features • Focuses on the applications of cryo-EM to structural biology • Documents the importance of cryo-EM/ET approaches in studying the structural determinants of cellular organelle and membrane protein biochemistry • Reviews the applications of high-resolution structures of viruses • Emphasizes structural insights of nuclear and gene machineries • Includes a section focused entirely on the applications of cryo-EM/ET in drug discovery and therapeutic development
Download or read book Energetic Basis of Structural Biology written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jung-Youn Lee
Publisher : Frontiers Media SA
ISBN 13 : 2889742636
Total Pages : 145 pages
Book Rating : 4.8/5 (897 download)
Download or read book Plasmodesmata: Recent Progress and New Insights written by Jung-Youn Lee and published by Frontiers Media SA. This book was released on 2022-04-25 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Elsevier
ISBN 13 : 0323991823
Total Pages : 462 pages
Book Rating : 4.3/5 (239 download)
Download or read book Scattering Methods in Structural Biology Part B written by and published by Elsevier. This book was released on 2023-01-12 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scattering Methods in Structural Biology, Part B, Volume 676 in the Methods in Enzymology serial, highlights advances in the field, presenting chapters on Quality controls, Refining biomolecular structures and ensembles by SAXS-driven molecular dynamics simulations, Data analysis and modelling of small-angle scattering data with contrast variation, Observing protein degradation in solution by the PAN-20S proteasome complex: state-of-the-art and future perspectives of TR-SANS as a complementary tool to NMR, crystallography and Cryo-EM, Extracting structural insights from chemically-specific soft X-ray scattering, Reconstruction of 3D density of biological macromolecules from solution scattering, ATSAS- present state and new developments in computational methods, and much more. Additional chapters cover Modeling Structure and Dynamics of Protein Complexes with SAXS Profiles (FoXSDock and MultiFoXS), Validation of macromolecular flexibility in solution by SAXS, Combining NMR, SAXS and SANS to characterize the structure and dynamics of protein complexes, Application of Molecular Simulation Methods to Analyze SAS Data, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology serial Updated release includes the latest information on Small Angle Scattering Methods for Structural Interpretation
Author : Bruce R. Donald
Publisher : MIT Press
ISBN 13 : 0262548798
Total Pages : 497 pages
Book Rating : 4.2/5 (625 download)
Download or read book Algorithms in Structural Molecular Biology written by Bruce R. Donald and published by MIT Press. This book was released on 2023-08-15 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of algorithms important to computational structural biology that addresses such topics as NMR and design and analysis of proteins.Using the tools of information technology to understand the molecular machinery of the cell offers both challenges and opportunities to computational scientists. Over the past decade, novel algorithms have been developed both for analyzing biological data and for synthetic biology problems such as protein engineering. This book explains the algorithmic foundations and computational approaches underlying areas of structural biology including NMR (nuclear magnetic resonance); X-ray crystallography; and the design and analysis of proteins, peptides, and small molecules. Each chapter offers a concise overview of important concepts, focusing on a key topic in the field. Four chapters offer a short course in algorithmic and computational issues related to NMR structural biology, giving the reader a useful toolkit with which to approach the fascinating yet thorny computational problems in this area. A recurrent theme is understanding the interplay between biophysical experiments and computational algorithms. The text emphasizes the mathematical foundations of structural biology while maintaining a balance between algorithms and a nuanced understanding of experimental data. Three emerging areas, particularly fertile ground for research students, are highlighted: NMR methodology, design of proteins and other molecules, and the modeling of protein flexibility. The next generation of computational structural biologists will need training in geometric algorithms, provably good approximation algorithms, scientific computation, and an array of techniques for handling noise and uncertainty in combinatorial geometry and computational biophysics. This book is an essential guide for young scientists on their way to research success in this exciting field.
Author : Paulo Ricardo Batista
Publisher : Frontiers Media SA
ISBN 13 : 2889766101
Total Pages : 148 pages
Book Rating : 4.8/5 (897 download)
Download or read book Integrative Structural Biology of Proteins and Macromolecular Assemblies: Bridging Experiments and Simulations written by Paulo Ricardo Batista and published by Frontiers Media SA. This book was released on 2022-07-26 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul C. Guest
Publisher : Springer Nature
ISBN 13 : 3031280121
Total Pages : 503 pages
Book Rating : 4.0/5 (312 download)
Download or read book Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19 written by Paul C. Guest and published by Springer Nature. This book was released on 2023-06-28 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
Author : David Davies
Publisher : Springer
ISBN 13 :
Total Pages : 540 pages
Book Rating : 4.:/5 (319 download)
Download or read book Structural Molecular Biology written by David Davies and published by Springer. This book was released on 1982-05 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural biology is undergoing a revolution in both the sophistication of new biophysical methods and the complexity of problems in biomolecular structure and organization opened up for study. These changes are directly attributable to major advances in computer technology, computational methods, development of high intensity synchrotron radiation sources, new magnetic resonance methods, laser optical techniques, etc. Structure-function problems previously considered intractable may now be solved. As this area of specialisation continues to expand, there is a need to review the various physical methods currently being used and developed in struc tural molecular biology. At the same time that individual techniques and their applications become more specialized, the need for effect ive communication between investigators gains in imperative. It is vital to forge links among sub-disciplines and to emphasise the complementary nature of results observed by different biophysical methods. This publication contains the review lectures given at a meeting on "Current Methods in Structural Molecular Biology" spon sored by NATO as an Advanced Study Institute and by FEBS ~s Advanced Course No. 78. The aim of the meeting was to bring together, in a teaching environment, students and specialists in diverse biophysical methodologies with the specific purpose of exploring, questioning and critically assessing the present and future state of biological structure research. The scientific content of the interdisciplinary Study Institute centred around three interrelated aspects; biophysical methods and instrumentation, their application to biological structure problems, and derivation of structural information and insights.
Author : Ângela Sousa
Publisher : Springer Nature
ISBN 13 : 1071631470
Total Pages : 462 pages
Book Rating : 4.0/5 (716 download)
Download or read book Advanced Methods in Structural Biology written by Ângela Sousa and published by Springer Nature. This book was released on 2023-04-24 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest integrated bioprocesses and technologies used to study the production of the target recombinant protein of therapeutic or diagnostic interest; its isolation, purification, and stabilization; and the bio-interaction and structural analyses. The chapters in this book are organized into four parts. Part One covers production methods of soluble and membrane proteins in prokaryotic and eukaryotic expression systems, such as Lactococcus lactis and Escherichia coli. Part Two describes traditional and novel approaches for recombinant protein purification and stabilization, and buffers and additives. Part Three discusses automated methods in structural biology based on in silico approaches; and Part Four provides examples of advanced protein investigation methodologies to assess structural analysis such as high-throughput protein crystallization and time-resolved serial crystallography. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Advanced Methods in Structural Biology is a valuable resource to those in academia (i.e., graduate students and postdoctoral researchers) and researchers in the pharmaceutical industry who wish to learn more about this developing field. Chapter 5 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Timir Tripathi
Publisher : Academic Press
ISBN 13 : 0323902650
Total Pages : 716 pages
Book Rating : 4.3/5 (239 download)
Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. Presents a thorough overview of the latest and emerging methods and technologies for protein study Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy Includes computational and machine learning methods Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins
Author : Xueyong Li
Publisher : Frontiers Media SA
ISBN 13 : 2832536085
Total Pages : 145 pages
Book Rating : 4.8/5 (325 download)
Download or read book Mining and Utilization of Favorable Gene Resources in Rice written by Xueyong Li and published by Frontiers Media SA. This book was released on 2023-10-18 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:
