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Author : Y. F. Law
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (141 download)
Download or read book Influence of Red Cell Deformability on Blood Viscosity written by Y. F. Law and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G. D. O. Lowe
Publisher : Springer Science & Business Media
ISBN 13 : 1447131053
Total Pages : 268 pages
Book Rating : 4.4/5 (471 download)
Download or read book Clinical Aspects of Blood Viscosity and Cell Deformability written by G. D. O. Lowe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and the basic scientific and clinical observations, which have helped to open up understanding of this highly important aspect of human physiology and pathology in recent years. The text is logically divided into five sections beginning with blood cell deformability, then moving on to theoretical consideration of blood rheology, followed by accounts of the interrelationships between rheology, blood flow and vascular occlusion. The final two sections deal with blood rheology in clinical practice and therapeutic aspects of the study of blood flow. As regards blood cell deformability (Section A), the basic problem is set out by Kiesewetter and colleagues in the first paragraph of chapter 1 (p. 3), in which they point out that whereas human erythrocytes at rest have a diameter of approxi mately 7. 5 /-tm, nutritive capillaries have diameters ranging from 3-5 /-tm, and chapters in section A give an account of the ways in which the red cell can undergo deformation to permit capillary perfusion and the maintenance of the microcirculation.
Author : Oguz Baskurt
Publisher : CRC Press
ISBN 13 : 1439841802
Total Pages : 326 pages
Book Rating : 4.4/5 (398 download)
Download or read book Red Blood Cell Aggregation written by Oguz Baskurt and published by CRC Press. This book was released on 2011-09-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
Author : Ingolf Bernhardt
Publisher : Springer Science & Business Media
ISBN 13 : 3662051818
Total Pages : 761 pages
Book Rating : 4.6/5 (62 download)
Download or read book Red Cell Membrane Transport in Health and Disease written by Ingolf Bernhardt and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: 51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.
Author : Terri L. Marble
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.:/5 (24 download)
Download or read book The Effect of Aerobic Training on Red Cell Deformability written by Terri L. Marble and published by . This book was released on 1990 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Douglas MacN. Surgenor
Publisher : Academic Press
ISBN 13 : 1483257509
Total Pages : 783 pages
Book Rating : 4.4/5 (832 download)
Download or read book The Red Blood Cell written by Douglas MacN. Surgenor and published by Academic Press. This book was released on 2013-10-22 with total page 783 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood cell. This book discusses the transport through red cell membranes; carrier-mediated glucose transport across human red cell membranes; and metabolism of methemoglobin in human erythrocytes. The interaction of oxygen and carbon dioxide with hemoglobin at the molecular level; physiological role of the oxyhemoglobin dissociation curve; hemoglobinopathies; and thalassemia syndromes are also deliberated. This publication likewise covers the red cell genetic polymorphisms; biological life of the red cell; clinical indications for red cells and blood; and biophysical behavior of red cells in suspensions. Other topics include the electrokinetic behavior of red cells; erythrocyte as a biopsy tissue in the evaluation of nutritional status; and knowledge of red cell purine and pyrimidine metabolism coming from the study of human disease. This volume is recommended for students, researchers, teachers, and physicians aiming to acquire knowledge of the red blood cell.
Author : Robert I. Weed
Publisher : Saunders
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Red Cell Membrane written by Robert I. Weed and published by Saunders. This book was released on 1971 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : M. Bessis
Publisher : Springer Science & Business Media
ISBN 13 : 3642670598
Total Pages : 418 pages
Book Rating : 4.6/5 (426 download)
Download or read book Red Cell Rheology written by M. Bessis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemolysis during filtration through micropores studied by Chien et al. [I] showed a dependence on pressure gradient and pore diameter that, at the time of publication, did not permit an easy interpretation of the hemolytic mechanism. Acting on the assumption that thresholds of hemolysis are easier to correlate with physical forces than extents of hemolysis, we performed a series of experi ments repeating some of the conditions reported in [I] and then focusing on low L1P in order to define better the thresholds of hemolysis for several pore sizes. Employing a model of a deformed red cell shape at the pore entrance (based on micropipette observations) we related the force field in the fluid to a biaxial tension in the membrane. The threshold for lysis correlated with a membrane tension of 30 dynes/cm. This quantity is in agreement with lysis data from a number of other investigators employing a variety of mechanisms for introduc ing membrane tension. The sequence of events represented here is: a. Fluid forces and pressure gradients deform the cell into a new, elongated shape. b. Extent of deformation becomes limited by the resistance of the cell mem brane to undergo an increase in area. c. Fluid forces and pressure gradients acting on the deformed cell membrane cause an increase in biaxial tension in the membrane. d. When the strain caused by this tension causes pores to open in the membrane, the threshold for hemolysis has been reached [2].
Author : Michael R. Pinsky
Publisher : Springer Science & Business Media
ISBN 13 : 3540373632
Total Pages : 367 pages
Book Rating : 4.5/5 (43 download)
Download or read book Applied Physiology in Intensive Care Medicine written by Michael R. Pinsky and published by Springer Science & Business Media. This book was released on 2007-05-19 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Te practice of intensive care medicine is at the very forefront of titration of treatment andmonitoringresponse. Te substrateofthiscareisthe criticallyill patientwho,by defnition, is at the limits of his or her physiologic reserve. Such patients need immediate, aggressive but balanced life-altering interventions to minimize the detrimental aspects of acute illness and hasten recovery. Treatmentdecisionsandresponsetotherapyareusually assessed by measures of physiologic function, such as assessed by cardio-respiratory monitoring. However, how one uses such information is ofen unclear and rarely supported by prospective clinical trials. In reality, the bedside clinician is forced to rely primarily on physiologic principles in determining the best treatments and response to therapy. However, the physiologic foundation present in practicing physicians is uneven and occasionally supported more by habit or prior training than science. A series of short papers published in Intensive Care Medicine since 2002 under the heading Physiologic Notes attempts to capture the essence of the physiologic perspectives that underpin both our understanding of disease and response to therapy. Tis present volume combines the complete list of these Physiologic Notes up until July 2006 with the ass o cia t ed r e vie w a r tic les o v er t h e s a m e in t er val t ha t a ls o addr ess e d t hes e cen tral issues.
Author : Gordon D.O. Lowe
Publisher : CRC Press
ISBN 13 : 0429523297
Total Pages : 237 pages
Book Rating : 4.4/5 (295 download)
Download or read book Clinical Blood Rheology written by Gordon D.O. Lowe and published by CRC Press. This book was released on 2019-06-04 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.
Author : Marcel Bessis
Publisher : Springer Verlag
ISBN 13 : 9780387059815
Total Pages : 767 pages
Book Rating : 4.0/5 (598 download)
Download or read book Living Blood Cells and Their Ultrastructure written by Marcel Bessis and published by Springer Verlag. This book was released on 1973 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Oguz Baskurt
Publisher : CRC Press
ISBN 13 : 1439841810
Total Pages : 310 pages
Book Rating : 4.4/5 (398 download)
Download or read book Red Blood Cell Aggregation written by Oguz Baskurt and published by CRC Press. This book was released on 2011-09-28 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Red blood cells in humans-and most other mammals-have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this real
Author : L. Dintenfass
Publisher : Springer Science & Business Media
ISBN 13 : 9780852004135
Total Pages : 502 pages
Book Rating : 4.0/5 (41 download)
Download or read book Blood Viscosity written by L. Dintenfass and published by Springer Science & Business Media. This book was released on 1985-03-31 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sylvi Persson
Publisher :
ISBN 13 :
Total Pages : 126 pages
Book Rating : 4.3/5 (91 download)
Download or read book Erythrocyte Deformability Studies by Viscometry and Filtrometry written by Sylvi Persson and published by . This book was released on 1994 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dr.Hakim Saboowala.
Publisher : Dr.Hakim Saboowala
ISBN 13 :
Total Pages : 30 pages
Book Rating : 4./5 ( download)
Download or read book What is the Clinical Implication of Whole Blood Viscosity in (Cardio)Vascular Medicine? written by Dr.Hakim Saboowala. and published by Dr.Hakim Saboowala. This book was released on 2019-10-09 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whole blood is a non-Newtonian fluid (A non-Newtonian fluid is a fluid that does not follow Newton's law of viscosity, i.e. constant viscosity independent of stress.), which means that its viscosity depends on shear rate. [Shear Rate: Shear rate is the rate of change of velocity at which one layer of fluid passes over an adjacent layer e.g. consider that a fluid is placed between two parallel plates that are 1.0 cm apart, the upper plate moving at a velocity of 1.0 cm/sec and the lower plate fixed.] At low shear, blood cells aggregate, which induces a sharp increase in viscosity, whereas at higher shear blood cells disaggregate, deform and align in the direction of flow. Other important determinants of blood viscosity are: · The Haematocrit, · The presence of Macromolecules in the medium, · Temperature and, · The deformability of Red blood cells (at high shear). At the sites of severe atherosclerotic obstructions or at vasospastic locations, when change of vessel diameter is limited, blood viscosity contributes to stenotic resistance thereby jeopardizing tissue perfusion. However, blood viscosity plays its most important role in the microcirculation where it contributes significantly to peripheral resistance and may cause sludging in the postcapillary venules. Apart from the direct haemodynamic significance, an increase in blood viscosity at low shear by red blood cell aggregation is also associated with increased thrombotic risk, as has been demonstrated in atrial fibrillation. Furthermore, as increased red blood cell aggregation is a reflection of inflammation, hyperviscosity has been shown to be a marker of inflammatory activity. Thus, because of its potential role in haemodynamics, thrombosis and inflammation, it has been attempted in this Booklet to emphasize the determination of the whole blood viscosity as it could provide useful information for diagnostics and therapy of(cardio)vascular disease. ……Dr.H.K.Saboowala.
Author : Oguz K. Baskurt
Publisher : IOS Press
ISBN 13 : 1586037714
Total Pages : 468 pages
Book Rating : 4.5/5 (86 download)
Download or read book Handbook of Hemorheology and Hemodynamics written by Oguz K. Baskurt and published by IOS Press. This book was released on 2007 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements and blood vessel walls, and on the microvascular aspects of hemodynamics. Since many aspects of hemorheology and hemodynamics are affected by disease or clinical states, these effects are discussed as are hyperviscosity syndromes, therapy for disturbed blood rheology, and methods in hemorheology and hemodynamics. Sections of the Handbook include History of Hemorheology; Hemorheology, covering basic aspects, blood composition, blood rheology, cell mechanics, pathophysiology, methods and comparative studies; Hemodynamics, covering basic principles, microcirculation, in vivo effects, endothelium and methods; and Clinical Aspects of Hemorheology, covering hyperviscosity, clinical significance and treatment. The goal is to foster greater interchange between workers in the fields so as to promote collaborative efforts and, hopefully, improved health. In selecting topics for this handbook the editors have attempted to provide a general overview of both basic science and clinical hemorheology and hemodynamics. Hemorheology and hemodynamics are closely related, the former dealing with all aspects of the flow and interactions of the individual blood cells mostly studied in vitro, the latter with the in vivo relationships among vessel architecture, driving pressure, flow rate and shear stress. The linkage between the in vitro and in vivo research described in the book will be of interest to both basic science and clinical investigators. The editors of the handbook have each been active in the fields of bio- and hemorheology for many years, and have published extensively. They have successfully achieved their objective to publish a well-written and well-edited handbook that will be valuable for researchers and students in the field.
Author : Dieter Platt
Publisher : Springer
ISBN 13 :
Total Pages : 242 pages
Book Rating : 4.3/5 (91 download)
Download or read book Blood Cells, Rheology and Aging written by Dieter Platt and published by Springer. This book was released on 1988 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the third Erlangen-Nuremberg symposium on experimental geronto logy we discussed the effect of aging on blood cells and rheology. Most studies with red cells have been performed on humans, rats, and rabbits. All these erythrocytes have no nucleus; the cells are therefore a model in which new synthesis of proteins is impossible. All the processes are age dependent except for exchange with the plasma. Investigations of red cells have attracted attention because of the latter's availability in large quantities from biochemists, physiologists, immunologists, and micro scopists. We now have a relative abundance of data on the biochemical and immunologic composition as well as on the ultrastructure of the cells. The second topic under discussion at the symposium was the immune system and cell receptors. One of the most apparent features of aging of the organism is progressive dysregulation of the immune system. As a result, the incidence of infection, cancer, and autoimmune and immune complex diseases increases. While we have a lot of new data on the function and differentiation of lymphoid cells, we have little informa tion on lymphocyte receptors during the aging process. Rheologic studies reflect changes in red cell deformability and blood coagulation. The erythrocyte deformability influences blood flow in all parts of the circulation. The fluidity of the red cell membranes controls whole blood viscosity. During aging, there are significant alterations in blood coagulation and hemostasis. One of the best known modifications of blood co agulation is a typical thrombophilic tendency with aging.
