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Author : Marcell Bronner
Publisher :
ISBN 13 :
Total Pages : 418 pages
Book Rating : 4.3/5 (91 download)
Download or read book Actinomycosis written by Marcell Bronner and published by . This book was released on 1971 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bozzano G Luisa
Publisher : Elsevier
ISBN 13 : 0080984339
Total Pages : 510 pages
Book Rating : 4.0/5 (89 download)
Download or read book Actinomycetes in Biotechnology written by Bozzano G Luisa and published by Elsevier. This book was released on 2012-12-02 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: The actinomycetes are a group of bacteria well known as producers of antibiotics. With the advent of molecular biology they have become important to biotechnologists in the search for new antibiotics, vitamins, enzyme inhibitors, etc. They also play an important role in the biodegradation of wastes, and their wide (natural) distribution in soil, composts, water and elsewhere in the environment makes them important to the agricultural and waste industries. This research book presents a broad view of the current interest in actinomycetes, ranging from isolation/screening of actinomycetes, discovery of new antibiotics, a substantial contribution on genetic manipulation to actinomycetes in agriculture, forestry, and the threat of actinomycetes as pollutants in the environment.The chapters, which have been written by experts, are intended to provide a balanced view of the opportunities and problems in an expanding field of interest.
Author : Adorjan Aszalos
Publisher : CRC Press
ISBN 13 : 9780824773588
Total Pages : 566 pages
Book Rating : 4.7/5 (735 download)
Download or read book Modern Analysis of Antibodies written by Adorjan Aszalos and published by CRC Press. This book was released on 1986-02-21 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an up-to-date account of instructions in the chemical and biological methods of analysis for antibiotics. It is helpful for all scientific workers in the diversified community of industrial, medical, academic, and governmental antibiotic laboratories.
Author : Stephen W. Queener
Publisher : Elsevier
ISBN 13 : 0323162932
Total Pages : 441 pages
Book Rating : 4.3/5 (231 download)
Download or read book Antibiotic-Producing Stetomyces written by Stephen W. Queener and published by Elsevier. This book was released on 1986-03-28 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bacteria: Volume IX: Antibiotic-Producing Streptomyces explores how Streptomyces, including actinomycetes, produce a variety of antibiotics such as aminocyclitols, ansamycins, macrolides, and tetracyclines. Topics covered range from physiology and fermentation to genetic recombination and chromosome mapping in Streptomyces, biomodification of antibiotics by Streptomyces, and biosynthesis of tylosin and erythromycin. The genome structure and evolution of Streptomyces are also discussed. This volume is comprised of 10 chapters and begins with a discussion on the taxonomy of Streptomyces based on morphology, physiological characteristics, the composition of cell constituents such as cell walls, and the presence of characteristic lipids, sugars, and quinones. The discussion then turns to the intraspecific and interspecific recombination in Streptomyces; pathways of DNA repair and mutagenesis in Streptomyces fradiae; strategies for isolation of improved Streptomyces mutants for antibiotic production; and derivation of DNA cloning vectors from Streptomyces phages. The biology and use of Streptomyces plasmids as cloning vectors are also described. The final chapter is devoted to major structural classes of antibiotics produced by Streptomyces, including anthracyclines and other quinones, ß-lactams, macrolides, nucleosides, peptides, polyenes, polyether antibiotics, and tetracyclines. This book will be of value to microbiologists, bacteriologists, biochemists, and biologists.
Author : Allen I. Laskin
Publisher :
ISBN 13 :
Total Pages : 305 pages
Book Rating : 4.:/5 (319 download)
Download or read book CRC Handbook of Microbiology written by Allen I. Laskin and published by . This book was released on 1977 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 covers the bacteria. Each chapter treats a group of bateria. Extensive bibliographies. A section on General information includes a glossary, taxonomy information, literature, etc. Taxonomic and topical indexes. Also a chapter on paleomicrobiology. Good overview plus factual information. Published 1977.
Author : Allen I. Laskin
Publisher :
ISBN 13 :
Total Pages : 616 pages
Book Rating : 4.:/5 (318 download)
Download or read book CRC Handbook of Microbiology written by Allen I. Laskin and published by . This book was released on 1977 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 1 covers the bacteria. Each chapter treats a group of bateria. Extensive bibliographies. A section on General information includes a glossary, taxonomy information, literature, etc. Taxonomic and topical indexes. Also a chapter on paleomicrobiology. Good overview plus factual information. Published 1977.
Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.F/5 ( download)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Author : Irwin Clyde Gunsalus
Publisher :
ISBN 13 : 9780123072092
Total Pages : 458 pages
Book Rating : 4.0/5 (72 download)
Download or read book Antibiotic-producing Streptomyces written by Irwin Clyde Gunsalus and published by . This book was released on 1986 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : D. A. Hopwood
Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetic Manipulation of Streptomyces written by D. A. Hopwood and published by . This book was released on 1985 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1967 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gordon M. Cragg
Publisher : CRC Press
ISBN 13 : 1439813825
Total Pages : 786 pages
Book Rating : 4.4/5 (398 download)
Download or read book Anticancer Agents from Natural Products, Second Edition written by Gordon M. Cragg and published by CRC Press. This book was released on 2011-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.
Author : John L. McGuire
Publisher : Wiley-VCH
ISBN 13 : 9783527298747
Total Pages : 736 pages
Book Rating : 4.2/5 (987 download)
Download or read book Pharmaceuticals, 4 Volume Set written by John L. McGuire and published by Wiley-VCH. This book was released on 2000 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry - an important segment of the chemical industry - is technologically prolific. Not only has it been historically successful in providing valuable new drugs, but its research and development laboratories have also made significant contributions to our understanding of disease. Mainly because of the success of the industry, people today can look forward to longer and healthier lives than ever before. Pharmaceuticals - Classes, Therapeutic Agents and Areas of Application provides an authoritative coverage of the subject area. Important pharmaceuticals and disease symptoms to be treated are discussed, along with a survey of the industry, regulatory aspects and the procedure to be followed from the discovery of a new pharmacologically active agent to its marketing as a drug. Internationally respected authors from both industry and academia in many of the world's major industrialized countries provide a complete picture. Top-quality illustrations, clear diagrams and charts, and the extensive use of tables enhance presentation and provide a unique level of detail, plus a keyword, author and a CAS-registry-number index round off the contents of this handbook. This work will be an invaluable source of information for pharmaceutical chemists, medicinal chemists, chemical engineers, patent attorneys, marketing specialists and all those involved in today's pharmaceutical industry.
Author : Thomas J. Dougherty
Publisher : Springer Science & Business Media
ISBN 13 : 1461414008
Total Pages : 1119 pages
Book Rating : 4.4/5 (614 download)
Download or read book Antibiotic Discovery and Development written by Thomas J. Dougherty and published by Springer Science & Business Media. This book was released on 2011-12-18 with total page 1119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Author :
Publisher : Academic Press
ISBN 13 : 008058358X
Total Pages : 370 pages
Book Rating : 4.0/5 (85 download)
Download or read book Annual Reports in Medicinal Chemistry written by and published by Academic Press. This book was released on 1979-11-14 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal Chemistry
Author : National Institutes of Health (U.S.). Division of Research Grants
Publisher :
ISBN 13 :
Total Pages : 1060 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1970 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. A. Mohamed Hatha
Publisher :
ISBN 13 : 9781536170467
Total Pages : 294 pages
Book Rating : 4.1/5 (74 download)
Download or read book A Closer Look at Actinomycetes written by A. A. Mohamed Hatha and published by . This book was released on 2020 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Actinomycetes are a versatile group of Gram positive bacteria widely distributed in the terrestrial and aquatic environments. The specialty of the actinomycetes is that they have a mycelial appearance unlike most bacteria. This group of bacteria is well known for their ability to produce a range of bioactive molecules, including antibiotics and various kinds of enzymes. As they are known for their ability to produce various antibiotics, the actinomycetes are widely explored by various research groups in search of novel drug molecules. Since the cultivation and maintenance of actinobacteria are not that easy as in the case of other bacteria, they are rather underexplored. With the frequent emergence of multidrug resistant bacteria, which are outpacing the discovery of new antibiotics, there is a renewed interest in actinomycetes from special habitats such as extreme habitats in the marine environment, salt pans, geothermal springs, permanently frozen polar environments etc. Endophytic actinomycetes are also attracting the attention of current researchers in this field. This book titled "A Closer Look at Actinomycetes" is a compilation of articles which deals with interesting topics such as "actinomycetes as microbial drug factories", endophytic fungi from special habitats of Pakistan as well as strategies for exploration of actinomycetes diversity and the taxonomy of actinomycetes should be of great interest to those who are interested in Actinomycetes research. People with interest in general microbiology will also find it an interesting read"--
Author : T. J. Franklin
Publisher : Springer Science & Business Media
ISBN 13 : 9400908253
Total Pages : 268 pages
Book Rating : 4.4/5 (9 download)
Download or read book Biochemistry of Antimicrobial Action written by T. J. Franklin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid advances made in the study of the synthesis, structure and function of biological macromolecules in the last fifteen years have enabled scientists concerned with antimicrobial agents to achieve a considerable measure of understanding of how these substances inhibit cell growth and division. The use of antimicrobial agents as highly specific inhibitors has in turn substantially assisted the investigation of complex biochemical pro cesses. The literature in Ihis field is so extensive however, that we considered an attempt should be made to draw together in an introductory book the more significant studies of recent years. This book, which is in fact based on lec ture courses given by us to undergraduates at Liverpool and Manchester Universities, is therefore intended as an introduction 'to the biochemistry of antimicrobial action for advanced students in many disciplines. We hope that it may also be useful to established scientists who are new to this area of research. The book is concerned with a discussion of medically important antimicro bial compounds and also a number of agents that, although having no medical uses, have proved invaluable as research tools in biochemistry. Our aim has been to esent pr the available information in a simple and readable way, emphasizing the established facts rather than more controversial material. Whenever possible, however, we have indicated the gaps in the present knowledge of the subject where further information is required.
