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Impurity
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Download or read book Impurity written by Ray Clark and published by Eternal Press. This book was released on 1916-05-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: When Detective Inspector Stewart Gardener investigates the discovery of a body in a run-down Victorian property in the suburb of Rawston near Leeds, he knows he's in for a tough time: ashen faced police constables testify to that.Nothing could have prepared him for what lay ahead.The corpse is beyond recognition.Distraught residents, drug dealers, pornographers, and paedophiles add to his list of complications, especially when they're all hiding something.With little time to recuperate, a second body, bearing the same hallmark is found in the grounds of a small church in the center of Leeds.Gardener's already overburdened work schedule is stretched beyond endurance. Over the last six months, children have been going missing: the dead body of the third child having recently been found on waste ground - naked, has instigated a murder hunt.He now knows he needs to find a deranged serial killer, but are the cases linked?With a complex murder case to unravel, the last thing he needs is another problem ... but life is about to deal Stewart Gardener a whole new deck of cards when the next child to go missing is his own...
Book Synopsis The Disposal of Impurity by : David Pearson Wright
Download or read book The Disposal of Impurity written by David Pearson Wright and published by . This book was released on 1987 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Measuring Elemental Impurities in Pharmaceuticals by : Robert Thomas
Download or read book Measuring Elemental Impurities in Pharmaceuticals written by Robert Thomas and published by CRC Press. This book was released on 2018-01-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent regulations on heavy metal testing have required the pharmaceutical industry to monitor a suite of elemental impurities in pharmaceutical raw materials, drug products and dietary supplements. These new directives s are described in the new United States Pharmacopeia (USP) Chapters , , and , together with Q3D, Step 4 guidelines for elemental impurities, drafted by the ICH (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use), a consortium of global pharmaceutical associations, including the European Pharmacopeia (Ph.Eur.), the Japanese Pharmacopeia (JP) and the USP. This book provides a complete guide to the analytical methodology, instrumental techniques and sample preparation procedures used for measuring elemental impurities in pharmaceutical and nutraceutical materials. It offers readers the tools to better understand plasma spectrochemistry to optimize detection capability for the full suite of elemental PDE (Permitted Daily Exposure) levels in the various drug delivery categories. Other relevant information covered in the book includes: The complete guide to measuring elemental impurities in pharmaceutical and nutraceutical materials. Covers heavy metals testing in the pharmaceutical industry from an historical perspective. Gives an overview of current USP Chapters and and ICH Q3D Step 4 Guidelines. Explains the purpose of validation protocols used in Chapter , including how J-values are calculated Describes fundamental principles and practical capabilities of ICP-MS and ICP-OES. Offers guidelines about the optimum strategy for risk assessment Provides tips on how best to prepare and present your data for regulatory inspection. An indispensable resource, the fundamental principles and practical benefits of ICP-OES and ICP-MS are covered in a reader-friendly format that a novice, who is carrying out elemental impurities testing in the pharmaceutical and nutraceutical communities, will find easy to understand.
Download or read book Impurity of Blood written by Joshua Goode and published by LSU Press. This book was released on 2009-12 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impurity of Blood analyzes the proposition of Spanish racial thought in the late 19th and early 20th centuries that racial strength came from a fusion of different groups, rather than from a kind of racial purity. By providing a history of ethnic thought in Spain in the medieval and early modern era, and by studying the formation of racial thought in Spain's nascent human sciences and its political and cultural manifestations leading into the Franco regime, it provides a new view of racial thought in Europe and its connections to the larger twentieth century formation of racial thought in the West.
Book Synopsis Analysis of Drug Impurities by : Richard J. Smith
Download or read book Analysis of Drug Impurities written by Richard J. Smith and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A key component of the overall quality of a pharmaceutical is control of impurities, as their presence, even in small amounts, may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Analytical science is developing rapidly and provides increasing opportunity to identify the structure, and therefore the origin and safety implications of these impurities, and the challenges of their measurement drives the development of modern quantitative methods. Written for both practicing and student analytical chemists, Analysis of Drug Impurities provides a detailed overview of the challenges and the techniques available to permit accurate identification and quantification of drug impurities.
Book Synopsis A Science of Impurity by : Christopher Hamlin
Download or read book A Science of Impurity written by Christopher Hamlin and published by Univ of California Press. This book was released on 1990-01-01 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Handbook of Isolation and Characterization of Impurities in Pharmaceuticals by : Satinder Ahuja
Download or read book Handbook of Isolation and Characterization of Impurities in Pharmaceuticals written by Satinder Ahuja and published by Academic Press. This book was released on 2003-07-18 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States Food and Drug Administration (FDA) and other regulatory bodies around the world require that impurities in drug substance and drug product levels recommended by the International Conference on Harmonisation (ICH) be isolated and characterized. Identifying process-related impurities and degradation products also helps us to understand the production of impurities and assists in defining degradation mechanisms. When this process is performed at an early stage, there is ample time to address various aspects of drug development to prevent or control the production of impurities and degradation products well before the regulatory filing and thus assure production of a high-quality drug product. This book, therefore, has been designed to meet the need for a reference text on the complex process of isolation and characterization of process-related (synthesis and formulation) impurities and degradation products to meet critical requlatory requirements. It's objective is to provide guidance on isolating and characterizing impurities of pharmaceuticals such as drug candidates, drug substances, and drug products. The book outlines impurity identification processes and will be a key resource document for impurity analysis, isolation/synthesis, and characterization. - Provides valuable information on isolation and characterization of impurities. - Gives a regulatory perspective on the subject. - Describes various considerations involved in meeting regulatory requirements. - Discusses various sources of impurities and degredation products.
Book Synopsis Intrinsic Point Defects, Impurities, and Their Diffusion in Silicon by : Peter Pichler
Download or read book Intrinsic Point Defects, Impurities, and Their Diffusion in Silicon written by Peter Pichler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the first comprehensive review of intrinsic point defects, impurities and their complexes in silicon. Besides compiling the structures, energetic properties, identified electrical levels and spectroscopic signatures, and the diffusion behaviour from investigations, it gives a comprehensive introduction into the relevant fundamental concepts.
Book Synopsis Impurity and Sin in Ancient Judaism by : Jonathan Klawans
Download or read book Impurity and Sin in Ancient Judaism written by Jonathan Klawans and published by Oxford University Press, USA. This book was released on 2004 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jonathan Klawans shows how the link between moral impurity and physical defilement, as understood by the ancient Hebrews, can be followed through to St Paul and the Christian era when the need for ritual purity was finally rejected.
Book Synopsis Gentile Impurities and Jewish Identities by : Christine E. Hayes
Download or read book Gentile Impurities and Jewish Identities written by Christine E. Hayes and published by Oxford University Press. This book was released on 2002-11-14 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: In ancient Jewish culture the ideas of purity and impurity defined the socio-cultural boundaries between Jews and Gentiles. Hayes argues that different views of the possibility of conversion, based on varying ideas about Gentile impurity, were the key factor in the formation of Jewish sects in the second temple period, and in the separation of the early Christian Church from what later became rabbinic Judaism.
Book Synopsis Genotoxic Impurities by : Andrew Teasdale
Download or read book Genotoxic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2011-03-29 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. The second section addresses the risk posed by genotoxic impurities from outside sources and from mutagens within DNA. In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.
Book Synopsis Characterization of Impurities and Degradants Using Mass Spectrometry by : Guodong Chen
Download or read book Characterization of Impurities and Degradants Using Mass Spectrometry written by Guodong Chen and published by John Wiley & Sons. This book was released on 2011-04-27 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights the current practices and future trends in structural characterization of impurities and degradants. It begins with an overview of mass spectrometry techniques as related to the analysis of impurities and degradants, followed by studies involving characterization of process related impurities (including potential genotoxic impurities), and excipient related impurities in formulated products. Both general practitioners in pharmaceutical research and specialists in analytical chemistry field will benefit from this book that will detail step-by-step approaches and new strategies to solve challenging problems related to pharmaceutical research.
Book Synopsis Pharmaceutical Industry Practices on Genotoxic Impurities by : Heewon Lee
Download or read book Pharmaceutical Industry Practices on Genotoxic Impurities written by Heewon Lee and published by CRC Press. This book was released on 2014-08-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, methods, interpretati
Book Synopsis Impurities in Semiconductors by : Victor I. Fistul
Download or read book Impurities in Semiconductors written by Victor I. Fistul and published by CRC Press. This book was released on 2004-01-27 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although there is a good deal of research concerning semiconductor impurities available, most publications on the subject are very specialized and very theoretical. Until now, the field lacked a text that described the current experimental data, applications, and theory concerning impurities in semiconductor physics. Impurities in Semicondu
Book Synopsis Identification and Determination of Impurities in Drugs by : S. Görög
Download or read book Identification and Determination of Impurities in Drugs written by S. Görög and published by Elsevier. This book was released on 2000-05-19 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis.Due to the very rapid development of the analytical methodologies available for this purpose and the similarly rapid increase of the demands as regards the purity of drugs it is an important task to give a summary of the problems and the various possibilities offered by modern analytical chemistry for their solution. That is the aim of this book.The book is methodology-oriented. In the first chapter some important aspects of the background of impurity-related analytical studies (toxicological, pharmacopoeial aspects, the characterisation of the sources of impurities and the role of impurity profiling in various fields of drug research, production and therapeutic use) are summarised. Chapter two deals with related organic impurities, the strategies for impurity profiling, the use of chromatographic and related separation methods, spectroscopic, and hyphenated techniques. The subject of the third chapter is the identification and determination of residual solvents. The determination of inorganic impurities is discussed in chapter four. The special problems of degradation products as impurities are dealt with in chapter five. A separate chapter has been compiled to deal with one of the most up-to-date problems in contemporary pharmaceutical analysis, the estimation of enantiomeric purity of chiral drugs. Chapter seven is devoted to various approaches to solve the problem of polymorphic modifications as impurities. Since in the broader sense of the word the microbiological purity of drugs and drug products also belongs to this circle, the most important information from this field is summarised in chapter eight. After the mainly methodology-oriented chapters, the final one concentrates on four groups of drugs (peptides, biotechnological products, antibiotics and steroids) in order to demonstrate the use of the methods described earlier.
Book Synopsis Defects and Impurities in Silicon Materials by : Yutaka Yoshida
Download or read book Defects and Impurities in Silicon Materials written by Yutaka Yoshida and published by Springer. This book was released on 2016-03-30 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emphasizes the importance of the fascinating atomistic insights into the defects and the impurities as well as the dynamic behaviors in silicon materials, which have become more directly accessible over the past 20 years. Such progress has been made possible by newly developed experimental methods, first principle theories, and computer simulation techniques. The book is aimed at young researchers, scientists, and technicians in related industries. The main purposes are to provide readers with 1) the basic physics behind defects in silicon materials, 2) the atomistic modeling as well as the characterization techniques related to defects and impurities in silicon materials, and 3) an overview of the wide range of the research fields involved.
Book Synopsis Metal Impurities in Silicon-Device Fabrication by : Klaus Graff
Download or read book Metal Impurities in Silicon-Device Fabrication written by Klaus Graff and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date monograph provides a thorough review of the relevant data and properties of the transition-metal impurities generated during silicon-sample and device fabrication. The different mechanisms responsible for contamination are discussed, and a survey is given of their impact on device performance. The specific properties of the main and rare impurities in silicon are examined, as well as the detection methods and requirements in modern technology. This new edition includes important recent data and many new tables.
