Implementation of Novel Tissue-engineering Strategies for Temporomandibular Joint Regeneration

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ISBN 13 : 9780355762983
Total Pages : pages
Book Rating : 4.7/5 (629 download)

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Book Synopsis Implementation of Novel Tissue-engineering Strategies for Temporomandibular Joint Regeneration by : Natalia Vapniarsky Arzi

Download or read book Implementation of Novel Tissue-engineering Strategies for Temporomandibular Joint Regeneration written by Natalia Vapniarsky Arzi and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This chapter provides evidence that minipig may be an optimal large animal model for human translational TMJ studies. Chapter 3 presents a comprehensive study that accomplishes the following: 1) It identifies a strategy for the development of allogeneic, biomimetic TMJ neotissue from minipig costal chondrocytes, using scaffold-free tissue-engineering and self-assembling process. 2) It addresses an urgent need for development of TMJ disc disease model in a large, skeletally mature animal. 3) It describes a novel strategy for surgical fixation of engineered tissue in the orthotopic environment. 4) It provides salient findings from an in vivo study evaluating the safety and efficacy of the tissue-engineered implants to repair TMJ disc defects in minipigs. Chapter 4 is a concise review discussing dermis as an alternative source of adult mesenchymal stem cells (MSC). The chapter first outlines the embryological development of human dermis stressing out the fact that although histologically similar, dermis in distinct anatomic locations has different developmental origin. Further, the chapter covers and compares different strategies utilized by various researchers to isolate and purify the MSC from dermis. Importantly, methods applied widely are evaluated for their accuracy in demonstrating stemness of these cells. The chapter culminates in summarizing applications of dermal MSC for tissue-engineering and regenerative cell therapies currently developed for various human pathologies, and providing future directions that would benefit the field. In summary, this dissertation delineates the cumulative progression of studies providing a successful platform for evaluation of novel tissue-engineering solutions for TMJ disc regeneration. The work begins with a comprehensive review of the disease, advantages, and limitations of the current treatment modalities and culminates in the demonstration of a novel strategy for disc regeneration in vivo. This work provides a solid foundation for future assessment of regenerative strategies directed at more advanced degenerative states of TMJ disc or larger, full thickness perforations. Furthermore, this platform can be optimized for regeneration of other fibrocartilaginous structures, such as the meniscus of the stifle joint and intervertebral disc.

Temporomandibular Disorders

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Publisher : National Academies Press
ISBN 13 : 0309670489
Total Pages : 427 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Temporomandibular Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Temporomandibular Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-01 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Temporomandibular disorders (TMDs), are a set of more than 30 health disorders associated with both the temporomandibular joints and the muscles and tissues of the jaw. TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain and irritable bowel syndrome. TMDs can be transient or long-lasting and may be associated with problems that range from an occasional click of the jaw to severe chronic pain involving the entire orofacial region. Everyday activities, including eating and talking, are often difficult for people with TMDs, and many of them suffer with severe chronic pain due to this condition. Common social activities that most people take for granted, such as smiling, laughing, and kissing, can become unbearable. This dysfunction and pain, and its associated suffering, take a terrible toll on affected individuals, their families, and their friends. Individuals with TMDs often feel stigmatized and invalidated in their experiences by their family, friends, and, often, the health care community. Misjudgments and a failure to understand the nature and depths of TMDs can have severe consequences - more pain and more suffering - for individuals, their families and our society. Temporomandibular Disorders: Priorities for Research and Care calls on a number of stakeholders - across medicine, dentistry, and other fields - to improve the health and well-being of individuals with a TMD. This report addresses the current state of knowledge regarding TMD research, education and training, safety and efficacy of clinical treatments of TMDs, and burden and costs associated with TMDs. The recommendations of Temporomandibular Disorders focus on the actions that many organizations and agencies should take to improve TMD research and care and improve the overall health and well-being of individuals with a TMD.

Novel Approaches Towards the Successful Implementation of Tissue Engineering Strategies in Impaction Bone Grafting

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Novel Approaches Towards the Successful Implementation of Tissue Engineering Strategies in Impaction Bone Grafting by : Edward Robert Tayton

Download or read book Novel Approaches Towards the Successful Implementation of Tissue Engineering Strategies in Impaction Bone Grafting written by Edward Robert Tayton and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tissue Engineering

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Publisher :
ISBN 13 : 9780867154641
Total Pages : 320 pages
Book Rating : 4.1/5 (546 download)

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Book Synopsis Tissue Engineering by : Samuel E. Lynch

Download or read book Tissue Engineering written by Samuel E. Lynch and published by . This book was released on 2008 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition reflects the remarkable clinical and scientific advances in bone and soft tissue reconstruction since publication of the first edition of this award-winning book 7 years ago. Highly potent recombinant growth factors are now widely available, and numerous chapters describe and provide cases illustrating how to incorporate these protein therapeutics into clinical practice. The reader will find information about the basic principles of tissue engineering, use of growth factors in orthopedics, and potential applications of gene therapy in dentistry. The book also features chapters on periodontal regeneration and localized implant site development. A section on applications for craniofacial reconstruction describes procedures for use of growth factors in the treatment of defects. The final section addresses orthopedic indications for tissue engineering. An invaluable, up-to-date resource for practitioners wanting to integrate tissue engineering into their clinical practice, researchers seeking inspiration for new directions, and those new to this fascinating field.

Bone Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 1135501912
Total Pages : 500 pages
Book Rating : 4.1/5 (355 download)

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Book Synopsis Bone Tissue Engineering by : Jeffrey O. Hollinger

Download or read book Bone Tissue Engineering written by Jeffrey O. Hollinger and published by CRC Press. This book was released on 2004-10-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Tissue Engineering of Temporomandibular Joint Cartilage

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1598299972
Total Pages : 122 pages
Book Rating : 4.5/5 (982 download)

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Book Synopsis Tissue Engineering of Temporomandibular Joint Cartilage by : Kyriacos Athanasiou

Download or read book Tissue Engineering of Temporomandibular Joint Cartilage written by Kyriacos Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2009-07-08 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. Table of Contents: The Temporomandibular Joint / Fibrocartilage of the TMJ Disc / Cartilage of the Mandibular Condyle / Tissue Engineering of the Disc / Tissue Engineering of the Mandibular Condyle / Current Perspectives

Regenerative Strategies for Maxillary and Mandibular Reconstruction

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Publisher : Springer
ISBN 13 : 3319936689
Total Pages : 278 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Regenerative Strategies for Maxillary and Mandibular Reconstruction by : James C. Melville

Download or read book Regenerative Strategies for Maxillary and Mandibular Reconstruction written by James C. Melville and published by Springer. This book was released on 2019-03-25 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as a comprehensive and up-to-date instructional guide to the strategies employed for regeneration of the maxillomandibular region, with emphasis on allogeneic and tissue engineering principles. Readers will find information on indications and contraindications for procedures, pertinent anatomy, surgical techniques, postoperative management, and management of complications. Current surgical techniques utilizing biotechnology for regeneration and reconstruction are described in depth, with explanation of their benefits in minimizing patient morbidity. In addition, state of the art free vascular transfer for maxillary and mandibular reconstruction is extensively discussed, with a particular focus on indications and step-by-step technique. The authors are well-known experts in their field who are keen to share their extensive experience and preferred approaches. The book is intended for all oral and maxillofacial surgeons, head and neck surgeons, and plastic and reconstruction surgeons who wish to increase their knowledge on the latest modalities of maxillary and mandibular reconstruction.

Bone and Cartilage Regeneration

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Publisher : Springer
ISBN 13 : 3319401440
Total Pages : 316 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Bone and Cartilage Regeneration by : Phuc Van Pham

Download or read book Bone and Cartilage Regeneration written by Phuc Van Pham and published by Springer. This book was released on 2017-01-24 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Recent Advances in Arthroplasty

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Publisher : BoD – Books on Demand
ISBN 13 : 9533079908
Total Pages : 630 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Recent Advances in Arthroplasty by : Samo Fokter

Download or read book Recent Advances in Arthroplasty written by Samo Fokter and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book was to offer an overview of recent insights into the current state of arthroplasty. The tremendous long term success of Sir Charnley's total hip arthroplasty has encouraged many researchers to treat pain, improve function and create solutions for higher quality of life. Indeed and as described in a special chapter of this book, arthroplasty is an emerging field in the joints of upper extremity and spine. However, there are inborn complications in any foreign design brought to the human body. First, in the chapter on infections we endeavor to provide a comprehensive, up-to-date analysis and description of the management of this difficult problem. Second, the immune system is faced with a strange material coming in huge amounts of micro-particles from the tribology code. Therefore, great attention to the problem of aseptic loosening has been addressed in special chapters on loosening and on materials currently available for arthroplasty.

Tissue Engineering

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Publisher : CRC Press
ISBN 13 : 143987400X
Total Pages : 801 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Tissue Engineering by : John P. Fisher

Download or read book Tissue Engineering written by John P. Fisher and published by CRC Press. This book was released on 2012-12-11 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue engineering research continues to captivate the interest of researchers and the general public alike. Popular media outlets like The New York Times, Time, and Wired continue to engage a wide audience and foster excitement for the field as regenerative medicine inches toward becoming a clinical reality. Putting the numerous advances in the field into a broad context, Tissue Engineering: Principles and Practices explores current thoughts on the development of engineered tissues. With contributions from experts and pioneers, this book begins with coverage of the fundamentals, details the supporting technology, and then elucidates their applications in tissue engineering. It explores strategic directions, nanobiomaterials, biomimetics, gene therapy, cell engineering, and more. The chapters then explore the applications of these technologies in areas such as bone engineering, cartilage tissue, dental tissue, vascular engineering, and neural engineering. A comprehensive overview of major research topics in tissue engineering, the book: Examines the properties of stem cells, primary cells, growth factors, and extracellular matrix as well as their impact on the development of tissue-engineered devices Focuses upon those strategies typically incorporated into tissue-engineered devices or utilized in their development, including scaffolds, nanocomposites, bioreactors, drug delivery systems, and gene therapy techniques Presents synthetic tissues and organs that are currently under development for regenerative medicine applications The contributing authors are a diverse group with backgrounds in academia, clinical medicine, and industry. Furthermore, this book includes contributions from Europe, Asia, and North America, helping to broaden the views on the development and application of tissue-engineered devices. The book provides a useful reference for courses devoted to tissue engineering fundamentals and those laboratories developing tissue-engineered devices for regenerative medicine therapy.

Oral and Maxillofacial Surgery for the Clinician

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Publisher : Springer Nature
ISBN 13 : 9811513465
Total Pages : 1965 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Oral and Maxillofacial Surgery for the Clinician by : Krishnamurthy Bonanthaya

Download or read book Oral and Maxillofacial Surgery for the Clinician written by Krishnamurthy Bonanthaya and published by Springer Nature. This book was released on 2021 with total page 1965 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book with CC BY 4.0 license. This comprehensive open access textbook provides a comprehensive coverage of principles and practice of oral and maxillofacial surgery. With a range of topics starting from routine dentoalveolar surgery to advanced and complex surgical procedures, this volume is a meaningful combination of text and illustrations including clinical photos, radiographs, and videos. It provides guidance on evidence-based practices in context to existing protocols, guidelines and recommendations to help readers deal with most clinical scenarios in their daily surgical work. This multidisciplinary textbook is meant for postgraduate trainees, young practicing oral surgeons and experienced clinicians, as well as those preparing for university and board certification exams. It also aids in decision-making, the implementation of treatment plans and the management of complications that may arise. This book is an initiative of Association of Oral and Maxillofacial Surgeons of India (AOMSI) to its commitment to academic medicine. As part of this commitment, this textbook is in open access to help ensure widest possible dissemination to readers across the world. ; Open access Unique presentation with contents divided into color-coded core competency gradations Covers all aspects of oral and maxillofacial surgery Supplemented with videos of all commonly carried out procedures as operative video Every chapter or topic concludes with "future perspective" and addresses cutting edge advances in each area Every topic has a pull out box that provides the most relevant systematic reviews/ key articles to every topic.

Tissue Engineering in Oral and Maxillofacial Surgery

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Publisher : Springer Nature
ISBN 13 : 3030245179
Total Pages : 169 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Tissue Engineering in Oral and Maxillofacial Surgery by : Riitta Seppänen-Kaijansinkko

Download or read book Tissue Engineering in Oral and Maxillofacial Surgery written by Riitta Seppänen-Kaijansinkko and published by Springer Nature. This book was released on 2019-12-02 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough, up-to-date description of the scientific basis and concepts of tissue engineering in the oral and maxillofacial region. The opening chapters present an introduction to tissue engineering, describe the roles of biomaterials and stem cells, discuss the use of growth factors, and examine potential adverse reactions. The challenges of soft and hard tissue engineering for oral and maxillofacial reconstruction are then considered in detail. It is explained what has been achieved to date, and potential future perspectives are explored. The importance and the verification of adequate vascularization are discussed, and a further focus is the use of 3D printing, both in the planning and production of scaffolds and in the bioprinting of cells and biomaterials. Information is also included on safety, efficacy, and regulatory aspects. Tissue Engineering in Oral and Maxillofacial Surgery will be of interest to all researchers and practitioners who wish to learn more about the potential of tissue engineering to revolutionize practice in oral and maxillofacial surgery.

Innovations and New Developments in Craniomaxillofacial Reconstruction

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Publisher : Springer Nature
ISBN 13 : 3030743225
Total Pages : 235 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Innovations and New Developments in Craniomaxillofacial Reconstruction by : Julio Acero

Download or read book Innovations and New Developments in Craniomaxillofacial Reconstruction written by Julio Acero and published by Springer Nature. This book was released on 2021-07-07 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of the new technologies that are having a tremendous impact on the complex field of craniomaxillofacial reconstructive surgery. Readers will find detailed information on the technologies themselves, their indications, and their benefits. The coverage encompasses the use of biomaterials and tissue engineering, virtual planning and CAD/CAM techniques, the various applications of computer-assisted surgery, and intraoperative navigation. Robotic surgery, endoscopic approaches, and piezoelectric surgery are each addressed within individual chapters. New developments in craniofacial pediatric surgery are discussed, and the book concludes by examining the present and future of facial transplantation. The text is supported by numerous high-quality color illustrations, and the team of authors comprises prestigious international leaders in the specialty. The book will be of value for all who are interested in learning about the innovations and developments that are reducing morbidity and improving outcomes in patients who require craniomaxillofacial reconstruction.

Injectable Biomaterials

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Publisher : Elsevier
ISBN 13 : 0857091379
Total Pages : 425 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Injectable Biomaterials by : Brent Vernon

Download or read book Injectable Biomaterials written by Brent Vernon and published by Elsevier. This book was released on 2011-01-24 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology.Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials.With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians. Comprehensively examines the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology Reviews the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites Explores clinical applications of injectable biomaterials, including drug delivery, tissue engineering, orthopaedic applications and injectable materials for gene delivery systems

Advances in Medical and Surgical Engineering

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Publisher : Academic Press
ISBN 13 : 012822603X
Total Pages : 422 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Advances in Medical and Surgical Engineering by : Waqar Ahmed

Download or read book Advances in Medical and Surgical Engineering written by Waqar Ahmed and published by Academic Press. This book was released on 2020-03-21 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Medical and Surgical Engineering integrates the knowledge and experience of experts from academia and practicing surgeons working with patients. The cutting-edge progress in medical technology applications is making the traditional line between engineering and medical science ever thinner. This is an excellent resource for biomedical engineers working in industry and academia on developing medical technologies. It covers challenges in the application of technology in the clinic with views from an editorial team that is highly experienced in engineering, biomaterials, surgical practice, biomedical science and technology, and that has a proven track record of publishing applied biomedical science and technology. For medical practitioners, this book covers advances in technology in their domain. For students, this book identifies the opportunities of research based on the reviews of utilization of current technologies. The content in this book can also be of interest to policymakers, research funding agencies, and libraries, that are contributing to development of medical technologies. Covers circulatory support, aortic valve implantation and microvascular antestmosis Explores arthroplasty of both the knee and the shoulder Includes tribology of materials, laser treatment and machining of biomaterial

Advanced Dental Biomaterials

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Publisher : Woodhead Publishing
ISBN 13 : 0081024770
Total Pages : 758 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Advanced Dental Biomaterials by : Zohaib Khurshid

Download or read book Advanced Dental Biomaterials written by Zohaib Khurshid and published by Woodhead Publishing. This book was released on 2019-05-24 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry. Provides a comprehensive review of the materials science, engineering principles and recent advances in dental biomaterials Reviews the fundamentals of dental biomaterials and examines advanced materials’ applications for tissues regeneration and clinical dentistry Written by an international collaborative team of materials scientists, biomedical engineers, oral biologists and dental clinicians in order to provide a balanced perspective on the field

A New Approach to Bone Regeneration

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Publisher :
ISBN 13 : 9788487673115
Total Pages : 277 pages
Book Rating : 4.6/5 (731 download)

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Book Synopsis A New Approach to Bone Regeneration by : Eduardo Anitua Aldecoa

Download or read book A New Approach to Bone Regeneration written by Eduardo Anitua Aldecoa and published by . This book was released on 2001 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: