Immunotherapy of Renal Cell Carcinoma

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642758533
Total Pages : 203 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Immunotherapy of Renal Cell Carcinoma by : Frans M.J. Debruyne

Download or read book Immunotherapy of Renal Cell Carcinoma written by Frans M.J. Debruyne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Kidney Cancer

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Publisher : Springer
ISBN 13 : 3319179039
Total Pages : 400 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Kidney Cancer by : Primo N. Lara

Download or read book Kidney Cancer written by Primo N. Lara and published by Springer. This book was released on 2015-06-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.

Cancer Immunotherapy Principles and Practice

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Author :
Publisher :
ISBN 13 : 9781620700976
Total Pages : 0 pages
Book Rating : 4.7/5 (9 download)

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Book Synopsis Cancer Immunotherapy Principles and Practice by : Lisa H. Butterfield

Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part 1: Intratumoral Signatures Associated With Immune Responsiveness

Nephron-Sparing Surgery

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Author :
Publisher : CRC Press
ISBN 13 : 0203089928
Total Pages : 160 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Nephron-Sparing Surgery by : Krishna Sasidharan

Download or read book Nephron-Sparing Surgery written by Krishna Sasidharan and published by CRC Press. This book was released on 2007-10-18 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the rising popularity of the minimally invasive laparoscopic option, open nephron-sparing surgery is still seen by many experts as the 'gold standard' for open surgery for kidney tumors and should remain the first choice for many patients. This challenges the idea that less-invasive therapies are always more desirable than open surgery. Whi

Contemporary Research on Renal Cell Carcinoma

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Publisher : Springer Science & Business Media
ISBN 13 : 364278609X
Total Pages : 224 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Contemporary Research on Renal Cell Carcinoma by : Gerd Staehler

Download or read book Contemporary Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of advanced renal cell carcinoma is still problematic. Surgery, although the therapy of choice for locally advanced renal tumors, is still controversial as the treatment for metastases. The role of surgery in the management of patients with pulmonary, bony, and liver metastasis is one of the subject matters discussed in this book. Our results with series of patients undergoing resection of metastases from the lung, bone, and liver show that surgery may be appropriate in selected patients with a good performance status, although most of them certainly cannot be cured by this procedure alone, i.e., in the absence of effective adjuvant therapies. As recent developments show, new strategies for immunotherapy of renal cell carcinoma represent a modest advance over traditional approaches in the treatment of this cancer, such as chemo- and radiotherapy. Clinical trials employing recombinant interferon-a and interleukin 2 produced response rates in up to 30% of patients treated, as evidenced by the European Immunotherapy Trials Program. The adverse reactions and the lack of efficacy in the majority of patients warrants the search for new immunotherapeutic approaches.

Renal Cell Carcinoma

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Author :
Publisher : CRC Press
ISBN 13 : 9780824790332
Total Pages : 370 pages
Book Rating : 4.7/5 (93 download)

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Book Synopsis Renal Cell Carcinoma by : Eric A. Klein

Download or read book Renal Cell Carcinoma written by Eric A. Klein and published by CRC Press. This book was released on 1993-04-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.

Immunotherapy of Renal Cell Carcinoma

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Author :
Publisher :
ISBN 13 : 9783642758546
Total Pages : 160 pages
Book Rating : 4.7/5 (585 download)

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Book Synopsis Immunotherapy of Renal Cell Carcinoma by : R. J. a Van Moorselaar

Download or read book Immunotherapy of Renal Cell Carcinoma written by R. J. a Van Moorselaar and published by . This book was released on 1991-01-29 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunotherapy in Renal Cell Carcinoma

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889769216
Total Pages : 107 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Immunotherapy in Renal Cell Carcinoma by : Walter J. Storkus

Download or read book Immunotherapy in Renal Cell Carcinoma written by Walter J. Storkus and published by Frontiers Media SA. This book was released on 2023-08-07 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunotherapy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030793087
Total Pages : 445 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Immunotherapy by : Aung Naing

Download or read book Immunotherapy written by Aung Naing and published by Springer Nature. This book was released on 2022-01-01 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. While immunotherapy has revolutionized the treatment landscape of several solid malignancies, several challenges still exist. Only a subset of patients derive clinical benefits; some do not respond at all, and others respond initially, only for their disease to progress later. Because these drugs can activate a broad range of immune cells, patients suffer from a unique set of side effects known as immune-related adverse events. As more immunotherapeutic agents are used in the clinic, it is important to provide updates about current and ongoing developments in the field to further research efforts and inform treatment decisions. The fourth edition will have a new focus on strategies to overcome the challenges associated with immunotherapy. Chapters will discuss topics such as biomarkers of response, resistance mechanisms, role of imaging in predicting immune-related adverse events, and management of immune-related adverse events. Written by leading experts conducting cutting-edge research, readers will gain up-to-date knowledge on the current state and future of immunotherapy.

Renal Cell Carcinoma

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592592295
Total Pages : 488 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Renal Cell Carcinoma by : Ronald M. Bukowski

Download or read book Renal Cell Carcinoma written by Ronald M. Bukowski and published by Springer Science & Business Media. This book was released on 2000-04-10 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal cell carcinoma represents a heterogeneous group of tumors, the most common of which is clear cell adenocarcinoma. The annual incidence of this tumor appears to be rising and approximately 12,000 individuals die from this cancer annually in the United States. One third of patients who present have metastatic disease at the time of diagnosis, and another 40% who undergo nephrectomy will ultimately develop this complication. Over the past 10 years, a significant amount of new information concerning the epidemiology, mole- lar and immunologic characteristics, and therapy for patients with these tumors has appeared. The recognition that inherited forms of renal cancer exist, and that chromosomal abn- malities can be identified in these tumors, suggested a genetic basis for renal cell carcinoma. The familial cancer syndrome, Von Hippel Lindau disease, provided the setting in which the genetic abnormalites associated with the development of renal cancer were first described. Abnormalities of the VHL gene have also been detected in sporadic clear cell carcinoma, and it has now been recognized that approximately 80 % of these tumors will demonstrate ch- acteristic alterations. Currently the functions of the VHL protein are being investigated, and the biology of clear cell carcinoma of the kidney is under study. Additionally, papillary carcinomas of the kidney appear to express different molecular defects, and these are now being unraveled.

Basic and Clinical Research on Renal Cell Carcinoma

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642768636
Total Pages : 288 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Basic and Clinical Research on Renal Cell Carcinoma by : Gerd Staehler

Download or read book Basic and Clinical Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Renal Cell Carcinoma (RCC) cannot be cured by surgery alone. Its resillience to irradiation and chemotherapy demands a new approach to the management of this disease. This book provides an overview of the scientific and clinical developments of RCC, and clarifies the fields ofimmunotherapy and immunobiology. The book contains a compilation of approaches that will enhance the effectiveness of the management of advancedRCC, even in the absence of definitive pre-clinical data. These require additional study and will stimulate the reassessment of preliminary results.Furthermore, preliminary results of already implemented clinical trials withbiological modifiers are presented. Of special interest are the current achievements in the field of immunotherapy using topically and subcutaneously low dosage combinations of cytokines. This concise volume will benefit those seeking a thorough review of the research and the clinical aspects of RCC simultaneously.

Chemotherapy and Immunotherapy in Urologic Oncology

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Publisher : Springer Nature
ISBN 13 : 3030520218
Total Pages : 303 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Chemotherapy and Immunotherapy in Urologic Oncology by : Edouard J. Trabulsi

Download or read book Chemotherapy and Immunotherapy in Urologic Oncology written by Edouard J. Trabulsi and published by Springer Nature. This book was released on 2020-09-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to familiarize clinical practitioners in systemic therapy options and medical management of urologic malignancies including prostate cancer, bladder and upper tract urothelial carcinoma, and renal cell carcinoma. Organized by organ system, the text highlights new therapies such as novel forms of androgen deprivation, cytotoxic chemotherapy, immune check point and immunomodulatory agents, and targeted therapies. Written by experts in the field, the book also reviews current chemotherapy and immunotherapy regimens for genitourinary malignancies and discusses indications, outcomes, and toxicities, as well as clinical trial concepts. Each of the book’s chapters offers a bulleted box of clinical pearls on the particular role of the APP. Chemotherapy and Immunotherapy in Urologic Oncology: A Guide for the Advanced Practice Provider is a resource for urologists, uro-radiologists, medical clinicians and family practitioners alike, familiarizing its audiences with systemic therapy regimens for urologic malignancies, as well as their expected outcomes and side effects.

Renal Cell Carcinoma

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Publisher : Springer
ISBN 13 : 149391622X
Total Pages : 620 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Renal Cell Carcinoma by : Ronald M. Bukowski

Download or read book Renal Cell Carcinoma written by Ronald M. Bukowski and published by Springer. This book was released on 2014-11-27 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​​ ​The third edition of this critically acclaimed book has updated and expanded the survey of clinical, biological and pathological management of localized and advanced renal cell carcinoma. Internationally renowned editors and contributors explore the latest developments in molecular genetics, focusing on the novel targets that have been discovered in epithelial renal tumors. Comprehensive and authoritative, Renal Cell Carcinoma: Molecular Targets and Clinical Applications, Third Edition is the definitive text on the rapidly evolving landscape of experimental therapeutics, written and edited by leaders of the field.​

Evolving Trends in Kidney Cancer

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Publisher : BoD – Books on Demand
ISBN 13 : 1838819592
Total Pages : 260 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Evolving Trends in Kidney Cancer by : Sashi S. Kommu

Download or read book Evolving Trends in Kidney Cancer written by Sashi S. Kommu and published by BoD – Books on Demand. This book was released on 2020-07-22 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney cancer imposes a significant cancer burden and its incidence continues to rise globally. Mortality in advanced kidney cancer remains high despite oncological, surgical and multimodal optimisation. Genetic associations, heterogeneity and limitations in early diagnosis through lack of optimal biomarkers add to the challenges. Over the last two decades there has been an exponential increase in diagnostic and therapeutic advances in the management of kidney cancer. The coupling of scientific advances in engineering and technology with oncological therapeutics has recently ushered a renewed optimism. The role of minimally invasive approaches through focal therapy and surgical extirpation using the robotic platform has been unprecedented and paramount. Virtual augmentation and mixed reality platforms have proved useful supplementary tools in surgical planning. The role of surgical simulation and training in development of surgeons with the optimal skill set is essential to provide optimal care. This book is the first in a series that explores the evolving trends in kidney cancer. The focus of the book is broad and includes topics ranging from immunotherapy to surgical simulation. Some chapters explore leading edge concepts while others capture the evolving trends and future concepts. The Editors aim to stimulate the readers to explore the key concepts and to encourage research and innovation along the main themes presented.

WHO Classification of Tumours of the Urinary System and Male Genital Organs

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Publisher :
ISBN 13 : 9789283224372
Total Pages : 400 pages
Book Rating : 4.2/5 (243 download)

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Book Synopsis WHO Classification of Tumours of the Urinary System and Male Genital Organs by : International Agency for Research on Cancer

Download or read book WHO Classification of Tumours of the Urinary System and Male Genital Organs written by International Agency for Research on Cancer and published by . This book was released on 2016-02-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Urinary System and Male Genital Organs is the eighth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. It contains numerous color photographs, MRIs, ultrasound images, CT scans, charts and references.

Rare Genitourinary Tumors

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Author :
Publisher : Springer
ISBN 13 : 3319300466
Total Pages : 372 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Rare Genitourinary Tumors by : Lance Pagliaro

Download or read book Rare Genitourinary Tumors written by Lance Pagliaro and published by Springer. This book was released on 2016-06-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rare Genitourinary Tumors offers the reader an up-to-date discussion of the less common neoplasms affecting the urinary tract and reproductive organs. Each authoritative chapter provides and in-depth discussion that is frequently not found in other urologic oncology textbooks. A valuable reference for urologists, oncologists, and those in specialty training, this volume provides ready access to information on etiology, incidence, risk factors, diagnosis, prognosis, insights from molecular pathology and, where applicable, data from clinical trials. The practical treatment guidelines included for each tumor type are written by experts and fully referenced.

Contemporary Research on Renal Cell Carcinoma

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Author :
Publisher : Springer
ISBN 13 : 9783540573753
Total Pages : 158 pages
Book Rating : 4.5/5 (737 download)

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Book Synopsis Contemporary Research on Renal Cell Carcinoma by : Gerd Staehler

Download or read book Contemporary Research on Renal Cell Carcinoma written by Gerd Staehler and published by Springer. This book was released on 1994-03-18 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The management of advanced renal cell carcinoma is still problematic. Surgery, although the therapy of choice for locally advanced renal tumors, is still controversial as the treatment for metastases. The role of surgery in the management of patients with pulmonary, bony, and liver metastasis is one of the subject matters discussed in this book. Our results with series of patients undergoing resection of metastases from the lung, bone, and liver show that surgery may be appropriate in selected patients with a good performance status, although most of them certainly cannot be cured by this procedure alone, i.e., in the absence of effective adjuvant therapies. As recent developments show, new strategies for immunotherapy of renal cell carcinoma represent a modest advance over traditional approaches in the treatment of this cancer, such as chemo- and radiotherapy. Clinical trials employing recombinant interferon-a and interleukin 2 produced response rates in up to 30% of patients treated, as evidenced by the European Immunotherapy Trials Program. The adverse reactions and the lack of efficacy in the majority of patients warrants the search for new immunotherapeutic approaches.