Immunopharmacology of Eosinophils

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Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunopharmacology of Eosinophils by : Harry Smith

Download or read book Immunopharmacology of Eosinophils written by Harry Smith and published by . This book was released on 1993 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eosinophil was identified more than a century ago, and at first dismissed as, at best, just another polymorphonuclear cell. Later, it was considered to play a pivotal role in countering the potentially damaging effects of mast cell degranulation via the production of neutralizing enzymes. Reappraisal followed with the demonstration of toxic effects of the eosinophil's cationic proteins. Instead of a cell with predominantly beneficial properties, the eosinophil was seen as actively contributing to the pathogeneisis of chronic inflammatory diseases such as asthma.

Eosinophils in Health and Disease

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Publisher : Academic Press
ISBN 13 : 012394385X
Total Pages : 679 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Eosinophils in Health and Disease by : James J. Lee

Download or read book Eosinophils in Health and Disease written by James J. Lee and published by Academic Press. This book was released on 2012-11-02 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.

Eosinophil-Associated Disorders, An Issue of Immunology and Allergy Clinics of North America

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323393381
Total Pages : 225 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Eosinophil-Associated Disorders, An Issue of Immunology and Allergy Clinics of North America by : Amy D. Klion

Download or read book Eosinophil-Associated Disorders, An Issue of Immunology and Allergy Clinics of North America written by Amy D. Klion and published by Elsevier Health Sciences. This book was released on 2015-08-03 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Immunology and Allergy Clinics of North America, Guest Edited by Amy D. Klion, MD and Princess U. Ogbogu, MD, is devoted to Eosinophil-Associated Disorders. Drs. Klion and Ogbogu have assembled a group of expert authors to review the following topics: Evaluation and Differential Diagnosis of Persistent Marked Eosinophilia; Spectrum of Eosinophilic End Organ Manifestations; Eosinophilia in GI disorders; Eosinophilia in Hematologic Disorders; Eosinophilia in Rheumatologic/Vascular Disorders; Eosinophilia in Pulmonary Disorders; Eosinophilia in Infectious Diseases; Eosinophilia associated with Immune Deficiency and Immune Dysregulation; Eosinophilia in Dermatologic disorders; Management of Hypereosinophilic Syndromes; and Novel Therapies for Eosinophilic Disorders.

Human Eosinophils

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Publisher : Karger Medical Scientific
ISBN 13 : 9783805569743
Total Pages : 0 pages
Book Rating : 4.5/5 (697 download)

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Book Synopsis Human Eosinophils by : Gianni Marone

Download or read book Human Eosinophils written by Gianni Marone and published by Karger Medical Scientific. This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The well-edited and stimulating material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine.

The Eosinophil in Health and Disease

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Author :
Publisher : Saunders
ISBN 13 :
Total Pages : 408 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Eosinophil in Health and Disease by : Adel A. F. Mahmoud

Download or read book The Eosinophil in Health and Disease written by Adel A. F. Mahmoud and published by Saunders. This book was released on 1980 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunopharmacology and Inflammation

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Publisher : Springer
ISBN 13 : 3319776584
Total Pages : 330 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Immunopharmacology and Inflammation by : Carlo Riccardi

Download or read book Immunopharmacology and Inflammation written by Carlo Riccardi and published by Springer. This book was released on 2018-06-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields.

Eosinophils in Allergy

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Publisher : S. Karger AG (Switzerland)
ISBN 13 : 9783805562164
Total Pages : 56 pages
Book Rating : 4.5/5 (621 download)

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Book Synopsis Eosinophils in Allergy by : Sohei Makino

Download or read book Eosinophils in Allergy written by Sohei Makino and published by S. Karger AG (Switzerland). This book was released on 1995-01-01 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immunopharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 0387779760
Total Pages : 275 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Immunopharmacology by : Manzoor M. Khan

Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.

Eosinophils, Allergy and Asthma

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Publisher : Wiley-Blackwell
ISBN 13 : 9780632028481
Total Pages : 176 pages
Book Rating : 4.0/5 (284 download)

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Book Synopsis Eosinophils, Allergy and Asthma by : A. Barry Kay

Download or read book Eosinophils, Allergy and Asthma written by A. Barry Kay and published by Wiley-Blackwell. This book was released on 1991-01-15 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eosinophil is a type of white blood cell which plays a crucial role in the immunological defence mechanisms of the human body. Professor Kay has brought together an internationally respected group of doctors and scientists to produce a research level monograph which describes the recent advances in understanding which have placed the eosinophil at the centre of numerous pathophysiological mechanisms underlying allergy and asthma. This up to date, state of the art treatise includes chapters on the molecular biology and immunology of the eosinophil, the interactions of eosinophils with other blood elements and with the major immunological mediators in the body such as interleukin-5, platelet activating factor. There is also detailed coverage of the very latest advances in the anti-allergic drug research which promise to revolutionise the therapy of allergy and asthma

Immunopharmacology of Respiratory System

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Publisher : Elsevier
ISBN 13 : 0080534554
Total Pages : 286 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Immunopharmacology of Respiratory System by : Stephen T. Holgate

Download or read book Immunopharmacology of Respiratory System written by Stephen T. Holgate and published by Elsevier. This book was released on 1995-10-18 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunopharmacology represents the boundary between the immune system and chemical mediators of the inflammatory and neuroendocrine responses. The subject as applied to the respiratory system embraces most of the common non-malignant lung diseases of which asthma and allied disorders are the most prevalent. An understanding of the underlying mechanisms of the disorders provides rationale for prevention and drug treatment as well as creating opportunities for novel drug development. Immunopharmacology of Respiratory System embraces all of these principles and should enable the reader to become rapidly updated in an area of medical importance. Focuses on aspects of disease pathogenesis that are common to a variety of lung disorders Includes coverage of the mechanisms of asthma - origin, progression, and novel therapeutic interventions This volume is another in the "Systems" section of the Handbook of Immunopharmacology

Immunopharmacology

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Publisher : Springer
ISBN 13 : 3319302736
Total Pages : 458 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Immunopharmacology by : Manzoor M. Khan

Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer. This book was released on 2016-06-21 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010. These events resulted in a gradually narrowing gap between early scientific knowledge and the late development of immune-based therapies. Consequently, the significance and magnitude of these advances warranted a revision of this contribution; this revised edition will provide a deeper understanding of the recent advances and discoveries related to the function of the immune response and their applications in the development of novel therapies to treat human diseases. Some of the key discoveries during the past five years include: the identification of the new subsets of helper T cells; new cytokines and their networks; and novel signal transduction mechanisms. For example, the identification of TH17 subset of helper T cells, in addition to TH1 and TH2 cells, not only advanced our understanding of the function of the basic immune response, but also raised our awareness of the possible etiology and pathogenesis of diseases such as allergy, asthma, rheumatoid arthritis, and other auto-immune/immune system based diseases. The newly identified powerful cytokine networks, that regulate both innate and acquired immune responses, emerged as a result of the finding of new cell types such as innate lymphoid cells and iNKT. Identification of the novel cytokines and their networks has advanced our knowledge of the mechanisms involved in the maintenance of tissue homeostasis, including inflammation and tissue repair during stress and injury. The development of HIV vaccines has also seen dramatic changes over the last few years. There has been a shift from a sole focus on T cell vaccines to a holistic approach that pertains to the induction of both humoral and cellular elements. This entails the induction of antibodies – both binding and neutralizing – to prevent infection. The cellular vaccination produces a safety net of CD8+ T-cell responses to suppress the replication of the virus in the infected patients, and both of the effector arms are aided by helper T cells. From the perspective of clinical applications, significant advances have also been made in: oral immunotherapy for allergic disease, the possible treatment of HIV infection, the development of new monoclonal antibodies and their fragments to treat human diseases, and immune cell based therapies for cancer.

Eosinophils in Allergy and Inflammation

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Publisher : CRC Press
ISBN 13 : 9780824791216
Total Pages : 536 pages
Book Rating : 4.7/5 (912 download)

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Book Synopsis Eosinophils in Allergy and Inflammation by : Gerald J. Gleich

Download or read book Eosinophils in Allergy and Inflammation written by Gerald J. Gleich and published by CRC Press. This book was released on 1993-11-09 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents the proceedings of a conference held at Adare Manor, County Limerick, Ireland. It provides an updated, in-depth review of the biological role of eosinophils in allergic diseases, summarizing basic knowledge of these unique cationic proteins. The book features an annotated discussion of the conference's post-presentation question-and-answer session.

Asthma

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Publisher : BoD – Books on Demand
ISBN 13 : 1789843154
Total Pages : 146 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Asthma by : Celso Pereira

Download or read book Asthma written by Celso Pereira and published by BoD – Books on Demand. This book was released on 2019-10-02 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a prevalent disease in all age groups that results from different pathogenic mechanisms, cells, and mediators engaged in innumerous clinical phenotypes and endotypes. This book exhaustively and didactically explores the biological expression of numerous cells and mediators involved in bronchial inflammation. The information provided aims at identifying the diversity and complexity of the interrelationships between the different players, drawing attention to critical mechanisms in asthma. It also highlights the requirement of new tools to identify strong biomarkers absolutely critical for managing asthma.

Immunopharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461572495
Total Pages : 432 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Immunopharmacology by : J. Hadden

Download or read book Immunopharmacology written by J. Hadden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunopharmacology: A New Discipline of Immense Potential Among the looming triumphs of the biologic revolution is the rapidly developing understanding of the mechanisms of bodily defense. In the short span of 35 years, knowledge of immunologic machinery has progressed from crudest description to major understanding in cellular and molecular terms. Antibodies, immunoglobulins, and the complement system have been almost completely defined in detailed molecular terms. Organs, like thymus, spleen and lymph nodes-so long enigmatic black boxes-are beginning to be understood not only in cellular terms but in molecular, physiologic, and endocrinologic terms. With this surging new information about the immune system comes the possi bility of developing a pharmacology which can modulate and control immunologic functions. Immunopharmacology most broadly conceived must address (1) control of development and function of the cellular components of the immunologic appara tus; (2) facilitation and suppression of function of the immunologically competent cells of the several subclasses, like T helpers, suppressors, and effectors, and B effectors and suppressors; (3) manipulation and repair of the major biologic amplifi cation systems, e. g. , the complement system and kinin-kallikrein system, and (4) utilization, modulation, and inhibition of the galaxy of molecules generated by T lymphocytes, the lymphokines. This new pharmacology must deal with the funda mental effector mechanisms of immunity, namely inflammation, phagocytosis, vascular reactivity, and blood coagulation. Furthermore, immunopharmacology must address and manipulate cell-cell communication and interaction, so vital to control of the immunological apparatus.

Immunopharmacology

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Publisher : Academic Press
ISBN 13 : 0124051847
Total Pages : 349 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Immunopharmacology by : David J Webb

Download or read book Immunopharmacology written by David J Webb and published by Academic Press. This book was released on 2013-02-18 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology explores the current state of Alzheimer's disease research and therapeutics. Chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Explores the current state of Alzheimer's disease research and therapeutics Chapters cover a variety of topics such as the B cell targeted therapies, lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Immunopharmacology of the Gastrointestinal System

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Publisher : London ; Toronto : Academic Press
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunopharmacology of the Gastrointestinal System by : John L. Wallace

Download or read book Immunopharmacology of the Gastrointestinal System written by John L. Wallace and published by London ; Toronto : Academic Press. This book was released on 1993 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.

Cells of the Immune System

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Publisher : BoD – Books on Demand
ISBN 13 : 1789855837
Total Pages : 248 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Cells of the Immune System by : Ota Fuchs

Download or read book Cells of the Immune System written by Ota Fuchs and published by BoD – Books on Demand. This book was released on 2020-05-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.