Immunology - Pasteur'S Heritage

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Publisher : New Age International
ISBN 13 : 9788122403206
Total Pages : 218 pages
Book Rating : 4.4/5 (32 download)

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Book Synopsis Immunology - Pasteur'S Heritage by : P.-A.. Cazenave

Download or read book Immunology - Pasteur'S Heritage written by P.-A.. Cazenave and published by New Age International. This book was released on 2003 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Unique Book. Although Pasteurs Seminal Contributions Are Known, The Background Leading To These Discoveries Has Been Admirably Recapitulated. How Studies To Help Sort The Problems Of Wine And Beer Industry Led To The Recognition Of Micro-Organisms As The Causative Factor, And To The Denunciation Of The Then Prevalent Views On Spontaneous Generation. The Inability Of An Aged Culture Of Fowl Cholera To Cause Disease In Chicken Was Not Dismissed As A Mistake, But Deduced To Make Two Observations Fundamental To Development Of Vaccines, Namely A Method To Attenuate The Virulence Of The Micro-Organisms And The Use Of Such Organisms As Vaccines.The Vaccine For Rabies Was A Landmark At A Time When No Electron Microscope Was Available To Visualize A Virus. Also This Was The First Use Of A Vaccine For Therapeutic Purposes! Pasteur S Heritage, The Institute That He Created And Scientists Who Worked With Him, And After Him, At This Institute Were Responsible For Discovery Of The Bacillus Causing Plague (And Also The Way It Spreads Through Fleas, An Observation Made By Them While Working In India), The Realization That The Symptoms Caused Bydiphtheria Were At A Point Distant Than The Infective Bacilli And Hence Due To A Toxin Elaborated; The Antisera For Tetanus Anddiphtheria; Bcg, The Attenuated Bovine Tuberculosis Bacillus For Vaccination Etc. Metchnikoff Laid The Basis Of Cellular Immunity, Bordet Discovered The Complement System.Part I Of The Book Provides Historical Insights On The Development Of Immunology In The Period Between The Two World Wars, The Pasteurian And The Grand Germanic School Of Koch, Ehrlich, And Von Behring, The Controversies Which Spurred Progress And Led To The Enrichment Of This Discipline. A Chapter In Part Ii Summarizes The Current Status Of The Vaccine, Which Have Historically Been The Most Cost Effective Agents For Control Of Diseases And Have Helped Eradicate Small Pox From The Surface Of The Globe.Part Iii Of The Book Has Two Thought Provoking Articles On The Philosophical Implications Of The Findings On Immune Mechanisms To Other Biological Processes. For Example Learning Is Not An Acquired Process From Outside. Instructive Theories On Antibody Formation Are Disproved. Instead, It Is Selection And Amplification That Prevails. The Book Concludes With An Enlightening Chapter On Perspectives In Modern Immunology. The Immune System Need Not Be Conceived For The Aggressive Function Of Combatingoutside Organisms. The Recognition Of Self Is Fundamental To Its Working.

Louis Pasteur

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781987491951
Total Pages : 58 pages
Book Rating : 4.4/5 (919 download)

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Book Synopsis Louis Pasteur by : Charles River Charles River Editors

Download or read book Louis Pasteur written by Charles River Charles River Editors and published by Createspace Independent Publishing Platform. This book was released on 2018-04-03 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: *Includes pictures *Includes quotes about Pasteur's life and work *Includes online resources and a bibliography for further reading "Do not let yourself be tainted with a barren skepticism." - Louis Pasteur While it would be impossible to name every individual who has contributed to the ever-advancing field of science, it almost goes without saying that one of the most important was Louis Pasteur, father of microbiology and modern immunology. Apart from propelling the field of vaccination to new heights, this visionary scientist would also revolutionize a significant part of the beverage industry, and highlight the importance of sterilization. These are only some of the extraordinary achievements on Louis' glaring résumé, one so well-rounded and extensive that it beggars belief. Like many other polymaths, this inspirational figure has become an unwitting incendiary, and he has attracted his fair share of critics over the years. Though undoubtedly one of the greatest intellectuals to have ever graced the world of science, Louis was also a conveniently private man steeped in scandal, fraudulence, and secrecy, which only makes his story all the more riveting. In 1995, which UNESCO declared "The Year of Pasteur," Louis Pasteur's name was posthumously disgraced on an international stage as a controversy ensued that would have certainly caused him to roll in his grave. Pasteur had remained a secretive man until the day of his death, even ordering his family members to hold onto his private journals and never disclose them to anyone. Most chalked it up to the man's introversion, and his secrets might have indeed died with him if not for his last surviving descendant, who donated the scientist's notes to the French National Library in the 1970s. Not only did Louis oversell some of his findings, he had, as it appears, unabashedly lied about the results of his experiments, and he has since been accused of stealing credit for some of his work. Concerning his rabies trials with the diseased mutts, for example, it was revealed that only 30 - a fraction of what Louis had reported - had been examined, and at least a third of them died from their illnesses. Most distressing of all, the "foolproof" vaccine he injected into the dogs was not the same vaccine he used on Joseph Meister, which meant that he had exposed the child to an untested treatment. On top of "regularly violat[ing] the standard conception of the scientific method," as Princeton University historian Gerald Geison puts it, Pasteur's work on anthrax, he claims, "is a clear example of scientific misconduct by the current definition." Rumor has it that Jean-Joseph Henri Toussaint, a local veterinarian, was conducting research on the bacterium at the same time, but Toussaint used a chemical formula he personally designed instead of oxygen. Enraptured by the progress he was making, Toussaint visited Pasteur and made the mistake of confiding in him the recipe for the chemical formula. Before Toussaint knew it, Pasteur had appropriated his formula, and began using it in his public experiments. At the end of the day, whether or not Louis Pasteur is fully deserving of all the credit he's received is still a matter of dispute, but one truth is incontestable. Pasteur revolutionized biology and ushered it into the modern era, and the institute erected in his honor continues to bring about tremendous advances that are slowly, but surely making the world a better place. Louis Pasteur: The Life and Legacy of the Legendary French Scientist Recognized as the Father of Microbiology examines the career that made Pasteur one of the 19th century's foremost scientists. Along with pictures of important people, places, and events, you will learn about Louis Pasteur like never before.

A History of Immunology

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Publisher : Academic Press
ISBN 13 : 012370586X
Total Pages : 553 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis A History of Immunology by : Arthur M. Silverstein

Download or read book A History of Immunology written by Arthur M. Silverstein and published by Academic Press. This book was released on 2009-06-17 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this innovative, short, new textbook, Rod Langman offers a conceptual framework within which students can understand the evolution of the immune system. Evolutionary selection for resistance to infectious disease is shown to be the driving force that has shaped the immune system into a remarkably effective and efficient system of defense. In the midst of the current information explosion in immunological science, when many students are under the impression that the immune system is almost too complex to understand as a whole, The Immune System can be used alone as a text for an introductory course or used in conjunction with any of the several descriptive texts already on the market.

Paul Ehrlich's Receptor Immunology

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Publisher : Elsevier
ISBN 13 : 0080538517
Total Pages : 231 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Paul Ehrlich's Receptor Immunology by : Arthur M. Silverstein

Download or read book Paul Ehrlich's Receptor Immunology written by Arthur M. Silverstein and published by Elsevier. This book was released on 2001-11-17 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul Ehrlich's Receptor Immunology: The Magnificent Obsession describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field. The selectionist theory of antibody formation Kinetics of primary and secondary antibody response Quantitative methods of measurement of antigens and antibody Demonstration of passive transfer of immunity from mother to foetus

The Private Science of Louis Pasteur

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Publisher : Princeton University Press
ISBN 13 : 1400864089
Total Pages : 418 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Private Science of Louis Pasteur by : Gerald L. Geison

Download or read book The Private Science of Louis Pasteur written by Gerald L. Geison and published by Princeton University Press. This book was released on 2014-07-14 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Private Science of Louis Pasteur, Gerald Geison has written a controversial biography that finally penetrates the secrecy that has surrounded much of this legendary scientist's laboratory work. Geison uses Pasteur's laboratory notebooks, made available only recently, and his published papers to present a rich and full account of some of the most famous episodes in the history of science and their darker sides--for example, Pasteur's rush to develop the rabies vaccine and the human risks his haste entailed. The discrepancies between the public record and the "private science" of Louis Pasteur tell us as much about the man as they do about the highly competitive and political world he learned to master. Although experimental ingenuity served Pasteur well, he also owed much of his success to the polemical virtuosity and political savvy that won him unprecedented financial support from the French state during the late nineteenth century. But a close look at his greatest achievements raises ethical issues. In the case of Pasteur's widely publicized anthrax vaccine, Geison reveals its initial defects and how Pasteur, in order to avoid embarrassment, secretly incorporated a rival colleague's findings to make his version of the vaccine work. Pasteur's premature decision to apply his rabies treatment to his first animal-bite victims raises even deeper questions and must be understood not only in terms of the ethics of human experimentation and scientific method, but also in light of Pasteur's shift from a biological theory of immunity to a chemical theory--similar to ones he had often disparaged when advanced by his competitors. Through his vivid reconstruction of the professional rivalries as well as the national adulation that surrounded Pasteur, Geison places him in his wider cultural context. In giving Pasteur the close scrutiny his fame and achievements deserve, Geison's book offers compelling reading for anyone interested in the social and ethical dimensions of science. Originally published in 1995. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Bibliography of the History of Medicine

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Publisher :
ISBN 13 :
Total Pages : 1308 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bibliography of the History of Medicine by :

Download or read book Bibliography of the History of Medicine written by and published by . This book was released on 1993 with total page 1308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Immune Self

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Publisher : Cambridge University Press
ISBN 13 : 9780521574433
Total Pages : 370 pages
Book Rating : 4.5/5 (744 download)

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Book Synopsis The Immune Self by : Alfred I. Tauber

Download or read book The Immune Self written by Alfred I. Tauber and published by Cambridge University Press. This book was released on 1994 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Self is the first extended philosophical critique of immunology.

The Biology and History of Molecular Biology: New Perspectives

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402002496
Total Pages : 276 pages
Book Rating : 4.0/5 (24 download)

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Book Synopsis The Biology and History of Molecular Biology: New Perspectives by : Sahotra Sarkar

Download or read book The Biology and History of Molecular Biology: New Perspectives written by Sahotra Sarkar and published by Springer Science & Business Media. This book was released on 1996-09-30 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of papers which reflect the recent trends in the philosophy and history of molecular biology. It brings together historians, philosophers, and molecular biologists who reflect on the discipline's emergence in the 1950's, its explosive growth, and the directions in which it is going. Questions addressed include: (i) what are the limits of molecular biology? (ii) What is the relation of molecular biology to older subdisciplines of biology, especially biochemistry? (iii) Are there theories in molecular biology? (iv) If so, how are these theories structured? (v) What role did information theory play in the rise of molecular biology? The book will open the way for many future researchers.

Rabies Symptoms, Diagnosis, Prophylaxis and Treatment

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Publisher : MDPI
ISBN 13 : 3038426822
Total Pages : 315 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Rabies Symptoms, Diagnosis, Prophylaxis and Treatment by : Charles Rupprecht

Download or read book Rabies Symptoms, Diagnosis, Prophylaxis and Treatment written by Charles Rupprecht and published by MDPI. This book was released on 2018-02-21 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Rabies Symptoms, Diagnosis, Prophylaxis and Treatment" that was published in TropicalMed

Posthumanism in Practice

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Publisher : Bloomsbury Publishing
ISBN 13 : 1350293814
Total Pages : 265 pages
Book Rating : 4.3/5 (52 download)

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Book Synopsis Posthumanism in Practice by : Christine Daigle

Download or read book Posthumanism in Practice written by Christine Daigle and published by Bloomsbury Publishing. This book was released on 2023-01-12 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Problematic assumptions which see humans as special and easily defined as standing apart from animals, plants, and microbiota, both consciously and unconsciously underpin scientific investigation, arts practice, curation, education, and research across the social sciences and humanities. This is the case particularly in those traditions emerging from European and Enlightenment philosophies. Posthumanism disrupts these traditional humanist outlooks and interrogates their profound shaping of how we see ourselves, our place in the world, and our role in its protection. In Posthumanism in Practice, artists, researchers, educators, and curators set out how they have developed and responded to posthumanist ideas across their work in the arts, sciences, and humanities, and provide examples and insights to support the exploration of posthumanism in how we can think, create, and live. In capturing these ideas, Posthumanism in Practice shows how posthumanist thought can move beyond theory, inform action, and produce new artefacts, effects, and methods that are more relevant and more useful for the incoming realities for all life in the 21st century.

The Cytokines of the Immune System

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Publisher : Academic Press
ISBN 13 : 0124200109
Total Pages : 320 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis The Cytokines of the Immune System by : Zlatko Dembic

Download or read book The Cytokines of the Immune System written by Zlatko Dembic and published by Academic Press. This book was released on 2015-05-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

Textbook of Immunology

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Publisher : JP Medical Ltd
ISBN 13 : 9350904748
Total Pages : 288 pages
Book Rating : 4.3/5 (59 download)

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Book Synopsis Textbook of Immunology by : SK Mohanty

Download or read book Textbook of Immunology written by SK Mohanty and published by JP Medical Ltd. This book was released on 2013-11-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition has been fully revised to provide the most up to date information in the field of immunology. Beginning with a brief history of the subject, the following chapters cover all aspects of immunology, from basic immunity and antigens, to immunodeficiency disorders including HIV, tumour immunology, and transplantation immunology. This concise second edition is highly illustrated with detailed graphics, colour diagrams, charts and tables, and each chapter features study questions and suggestions for further reading. Key points Fully revised, second edition, providing latest information on complete field of immunology Highly illustrated with graphics, diagrams, charts and tables Study questions and further reading suggestions included in each chapter Previous edition published in 2007

Jews and Medicine

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Publisher : KTAV Publishing House, Inc.
ISBN 13 : 9780881257731
Total Pages : 788 pages
Book Rating : 4.2/5 (577 download)

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Book Synopsis Jews and Medicine by : Frank Heynick

Download or read book Jews and Medicine written by Frank Heynick and published by KTAV Publishing House, Inc.. This book was released on 2002 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Middle East B.C.E. to medieval Spain through the end of WWII, Frank Heynick traces the relationship between a people and a science in Jews and Medicine: An Epic Saga. The ancient ritual of circumcision, Maimonides, the Bavarian Jacob Henle and Nobel-winner Otto Loewi make appearances in this sweeping history of literary, religious and professional links between Judaism and medical practice. Heynick, a scholar of medical history and linguistics, discusses the sale of mummified remains as a cure for disease, the ascendance of psychoanalysis and hundreds of other famous and obscure historical moments. -Publisher's Weekly.

Science as Autobiography

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Publisher : Yale University Press
ISBN 13 : 0300128711
Total Pages : 387 pages
Book Rating : 4.3/5 (1 download)

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Book Synopsis Science as Autobiography by : Thomas Soderqvist

Download or read book Science as Autobiography written by Thomas Soderqvist and published by Yale University Press. This book was released on 2008-10-01 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This biography probes the unusual mind, the dramatic life, and the outstanding scientific work of Danish-born immunologist Niels Jerne (1911–1994). Jerne’s Nobel Prize-winning achievements in the field of immunology place him in the pantheon of great twentieth-century biomedical theorists, yet his life is perhaps even more interesting than his science. Science as Autobiography tells Jerne’s story, weaving together a narrative of his life experiences, emotional life, and extraordinarily creative scientific work. A legendary figure who preferred an afternoon of conversation in a Paris wine bar to work in the laboratory, Jerne was renowned for his unparalleled powers of concentration and analytical keenness as well as his dissonant personal life. The book explores Jerne the man and scientist, making the fascinating argument that his life experience and view of himself became a metaphorical resource for the construction of his theories. The book also probes the moral issues that surrounded Jerne’s choice to sacrifice his family in favor of scientific goals and the pursuit of excellence.

Physiologic Autoimmunity and Preventive Medicine

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Publisher : Bentham Science Publishers
ISBN 13 : 1608057240
Total Pages : 254 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Physiologic Autoimmunity and Preventive Medicine by : Alexander B. Poletaev

Download or read book Physiologic Autoimmunity and Preventive Medicine written by Alexander B. Poletaev and published by Bentham Science Publishers. This book was released on 2013-06-03 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system is a natural component, regulator and direct participant in the physiological activities in a healthy body. A considerable number of immune functions, including those related to antimicrobial defense, derive from autoclearance as well as construction and support of multicellularity. Various pathological processes in any organ are usually accompanied by different patterns of cell death and, thus, by increased exposure and presentation of self antigens. These events induce the secondary rise in production of autoantibodies with appropriate specificity (opsonins), which provides augmentation of clearance by facilitating the efficacy of macrophage-dependent consumption of debris in the affected organ. Secondary changes in production and serum content of autoantibodies can be considered the universal and earliest detectable marker of any chronic disease. Experimental and clinical production antibodies reveal antibodies against nuclear antigens, which penetrate into living cell nuclei and alter nuclear acid synthesis, cell proliferation and function. Autoantibodies can thus be regarded as hormone-like bioregulators of gene expression. The immune system is apparently able to reproduce complementary regulators for various cell receptors, including nuclear ones. The book focuses on physiological autoimmunity models and delves into the relation between autoimmunity and autoallergy in the context of disease prevention and prediction. The E-book is a unique and comprehensive monograph and includes a history and contemporary research on natural autoimmunity - a fundamental concept essential for many branches of medicine and pathology. The concepts described in this e-book also have broad practical implications for the healthcare sector, because it establishes effective method of early prediction for many different diseases and creates a basis for prophylaxis. The reference gives medical and clinical professionals a chance to revisit old dogmas and acquire fruitful perspectives for theoretical reasoning and research planning.

Global Transformations in the Life Sciences, 1945–1980

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Publisher : University of Pittsburgh Press
ISBN 13 : 0822986051
Total Pages : 336 pages
Book Rating : 4.8/5 (229 download)

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Book Synopsis Global Transformations in the Life Sciences, 1945–1980 by : Patrick Manning

Download or read book Global Transformations in the Life Sciences, 1945–1980 written by Patrick Manning and published by University of Pittsburgh Press. This book was released on 2018-06-29 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second half of the twentieth century brought extraordinary transformations in knowledge and practice of the life sciences. In an era of decolonization, mass social welfare policies, and the formation of new international institutions such as UNESCO and the WHO, monumental advances were made in both theoretical and practical applications of the life sciences, including the discovery of life’s molecular processes and substantive improvements in global public health and medicine. Combining perspectives from the history of science and world history, this volume examines the impact of major world-historical processes of the postwar period on the evolution of the life sciences. Contributors consider the long-term evolution of scientific practice, research, and innovation across a range of fields and subfields in the life sciences, and in the context of Cold War anxieties and ambitions. Together, they examine how the formation of international organizations and global research programs allowed for transnational exchange and cooperation, but in a period rife with competition and nationalist interests, which influenced dramatic changes in the field as the postcolonial world order unfolded.

Stalin's Secret Weapon

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Publisher : Oxford University Press, USA
ISBN 13 : 0190928859
Total Pages : 278 pages
Book Rating : 4.1/5 (99 download)

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Book Synopsis Stalin's Secret Weapon by : Anthony Rimmington

Download or read book Stalin's Secret Weapon written by Anthony Rimmington and published by Oxford University Press, USA. This book was released on 2018-11-15 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stalin's Secret Weapon is a gripping account of the early history of the globally significant Soviet biological weapons program, including its key scientists, its secret experimental bases and the role of intelligence specialists, establishing beyond doubt that the infrastructure created by Stalin continues to form the core of Russia's current biological defense network. Anthony Rimmington has enjoyed privileged access to an array of newly available sources and materials, including declassified British Secret Intelligence Service reports. The evidence contained therein has led him to conclude that the program, with its network of dedicated facilities and proving grounds, was far more extensive than previously considered, easily outstripping those of the major Western powers. As Rimmington reveals, many of the USSR's leading infectious disease scientists, including those focused on pneumonic plague, were recruited by the Soviet military and intelligence services. At the dark heart of this bacteriological archipelago lay Stalin, and his involvement is everywhere to be seen, from the promotion of favored researchers to the political repression and execution of the lead biological warfare specialist, Ivan Mikhailovich Velikanov.