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Immunological Perspectives Of A Host Parasite System
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Book Synopsis Immunological Perspectives of a Host-parasite System by : Carl A. Boswell
Download or read book Immunological Perspectives of a Host-parasite System written by Carl A. Boswell and published by . This book was released on 1985 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The host snail Biomphalaria glabrata and the parasitic trematode Schistosoma mansoni are valuable subjects for studies evaluating and defining immunological parameters that determine the outcome of individual host-parasite encounters. In this thesis, both soluble and cellular components of the snail's hemolymph were examined to gain insight into the basis for resistance and susceptibility to the parasite. Because agglutinins have antibody-like activity (e.g. agglutinate particles with appropriate surface ligands, some have been found on cell surfaces) they are considered by many to be immunoglobulin analogs. An agglutinin was isolated from snail plasma, its physicochemical properties defined, and its possible role in the snail-parasite interaction examined. The presence of additional agglutinins is inferred from cross-adsorption experiments. It is known that the plant lectin concanavalin A binds to the surface of both hemocytes and sporocysts. I therefore tested the hypothesis that bringing hemocytes from susceptible (compatible) snails into contact with sporocysts in the presence of a cross-linking, or "bridging", reagent would result in sporocyst killing. Data are presented showing that indeed sporocyst death increased dramatically when such an encounter occurred. While hemocyte cytotoxicity is induced by Con A treatment of sporocysts, further investigation revealed that bridging between the target and effector does not appear to be the inducing mechanism. It is suggested that Con A treatment of sporocysts causes them to reveal surface markers that normally benign hemocytes recognize as foreign, which then triggers a cytotoxic reaction by the hemocytes. These results are discussed in the context of lectin-dependent cell-mediated cytotoxicity reported for murine cytotoxic T-lymphocytes. Studies of this type will lead to greater understanding of host-parasite immunobiology and of the evolutionary origins of the vertebrate immune system.
Book Synopsis Immunity to Parasites by : Derek Wakelin
Download or read book Immunity to Parasites written by Derek Wakelin and published by Cambridge University Press. This book was released on 1996-08-13 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.
Download or read book Defending Life written by Elling Ulvestad and published by Springer Science & Business Media. This book was released on 2007-05-11 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defending Life discusses the relationship between hosts and parasites. It contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. Its emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations and increases the understanding of why we observe what we observe.
Download or read book Defending Life written by Elling Ulvestad and published by Springer. This book was released on 2007-04-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defending Life discusses the relationship between hosts and parasites. It contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications. Its emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations and increases the understanding of why we observe what we observe.
Download or read book Eco-immunology written by Davide Malagoli and published by Springer Science & Business Media. This book was released on 2014-04-11 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a cutting-edge contribution giving an all-around perspective of eco-immunology today. Beside questions of the utmost importance for the whole community of immunologists, e.g, the intrinsic limits of immunological experiments performed at the bench on a limited number of selected models, the book covers several other facets of the eco-immunological approach, including host-parasite interactions, human aging and population immunology. Throughout the book the importance of population dynamics and evolutionary diversification of immune systems is frequently recalled, and makes the reader aware of the basic similarities and differences existing between humans and the models adopted for studying human immune system. The evidenced differences have been recently challenging the reliability of several established animal models and in the book it is discussed for the first time in analytical terms whether mice are reliable models of human inflammatory disorders.
Book Synopsis Immunity to Parasitic Infection by : Tracey Lamb
Download or read book Immunity to Parasitic Infection written by Tracey Lamb and published by John Wiley & Sons. This book was released on 2012-08-10 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitic infections remain a significant cause of morbidity and mortality in the world today. Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system. This book examines current knowledge about immune responses to parasitic infections affecting humans, including interactions that occur during co-infections, and how immune responses may be manipulated to develop therapeutic interventions against parasitic infection. For easy reference, the most commonly studied parasites are examined in individual chapters written by investigators at the forefront of their field. An overview of the immune system, as well as introductions to protozoan and helminth parasites, is included to guide background reading. A historical perspective of the field of immunoparasitology acknowledges the contributions of investigators who have been instrumental in developing this field of research.
Book Synopsis Genetics of Host and Parasite by : D. Wakelin
Download or read book Genetics of Host and Parasite written by D. Wakelin and published by Cambridge University Press. This book was released on 1996 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of articles, edited by D. Wakelin and D. Walliker include: Genetic variability in parasites and host-parasite interactions; Host genetics and infectious disease; T cell and cytokine basis of host variability in response to intestinal nematode infections; The role of MHC- and non-MHC-associated genes in determining the human immune response to malaria antigens; Influence of host and parasite genotypes on immunological control of Theileria parasites; Genetic susceptibility to leishmanial infections: studies in mice and man; Genetic susceptibility to malaria and other infectious diseases: from MHC to the whole genome. This volume is the specially commissioned supplement to the journal Parasitology, volume 112.
Book Synopsis Biochemical, Immunological and Epidemiological Analysis of Parasitic Diseases by : P.K. Bandyopadhyay
Download or read book Biochemical, Immunological and Epidemiological Analysis of Parasitic Diseases written by P.K. Bandyopadhyay and published by Springer Nature. This book was released on 2022-01-07 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews various vector-borne diseases and their control methods. It discusses morphology, life history, and pathogenicity of protozoan and helminth parasites. Further, it analyzes host-parasite interactions and their adaptation within the host system for understanding parasitic infections. The book discusses the complex life cycle, biochemical adaptations, and molecular biology of the parasites. It investigates the immunological response to different infectious agents and explores new targets for combined therapeutic approaches. It also summarizes the evolution of parasitism and the ecology of parasites of the different phylum. Lastly, it provides information on vector biology emphasizing the role of basic vector research in developing future disease control methods and improving upon the existing approaches.
Book Synopsis Immune Recognition and Evasion: Molecular Aspects of Host–Parasite Interaction by : L.H.T. Van Der Ploeg
Download or read book Immune Recognition and Evasion: Molecular Aspects of Host–Parasite Interaction written by L.H.T. Van Der Ploeg and published by Elsevier. This book was released on 2012-12-02 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction reviews recent advances in understanding the genetic basis of host-parasite interactions, with emphasis on antigenic epitopes, the genetics of parasites, the molecular mechanisms of immune recognition and evasion, and the way that cytokines and hormones act on host-parasite interactions. Organized into four parts encompassing 25 chapters, this volume begins with an overview of the genomic organization of the T cell receptor genes and the contribution of non-B DNA structures to switch recombination in immunoglobulin genes. It then discusses signal transduction by class II molecules encoded by the major histocompatibility complex la and the biological consequences of this process; allelic polymorphism of HLA class II antigens and its connection to the molecular basis of autoimmunity; mimicry between HLAB27 and bacteria; and genetic control of susceptibility to helminth infection. The reader is also introduced to recognition of protein antigens by antibodies; recognition of influenza antigens by class I-restricted cytotoxic T lymphocytes; the biochemical basis of cachexia of infection; mechanisms of antigenic variation in Plasmodium; and rational design of trypanocidal drugs. Geneticists and molecular biologists will gain valuable information from this book.
Book Synopsis Host-Parasite Relationships and the Yersinia Model by : Akira Wake
Download or read book Host-Parasite Relationships and the Yersinia Model written by Akira Wake and published by Springer. This book was released on 2011-11-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects oflife at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for replicating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macro molecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living systems. It might be said that these few decades have replaced a near vacuum of informa tion with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective what is known about the field today - and a description of the frontiers of research where our knowledge is increasing steadily.
Book Synopsis Host Manipulation by Parasites by : David P. Hughes
Download or read book Host Manipulation by Parasites written by David P. Hughes and published by Oxford University Press. This book was released on 2012-06-07 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasites that manipulate the behaviour of their hosts represent striking examples of adaptation by natural selection. This text provides an authoritative review of host manipulation by parasites that assesses developments in the field and lays out a framework for future research.
Book Synopsis Some Biochemical and Immunological Aspects of Host-parasite Relationships by :
Download or read book Some Biochemical and Immunological Aspects of Host-parasite Relationships written by and published by . This book was released on 1964 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pathogenesis, Treatment and Prevention of Leishmaniasis by : Mukesh Samant
Download or read book Pathogenesis, Treatment and Prevention of Leishmaniasis written by Mukesh Samant and published by Academic Press. This book was released on 2021-08-18 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
Book Synopsis The Biology of Parasitism by : Paul T. Englund
Download or read book The Biology of Parasitism written by Paul T. Englund and published by . This book was released on 1988 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Woods Hole Marine Biological Laboratory--an up-to-date survey of molecular and immunological approaches to the study of parasites responsible for human disease. These concise, provocative essays present empirical findings and personal accounts and critically review current models and theories. Chapters are divided into three sections: the biology of parasites and parasitic disease; parasite immunology; and parasite molecular biology, biochemistry, and genetics. The contributors do not always present the same viewpoint, which makes for lively reading.
Book Synopsis Malaria Immunology by : Peter Perlmann
Download or read book Malaria Immunology written by Peter Perlmann and published by Karger Medical and Scientific Publishers. This book was released on 2002-01-01 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.
Book Synopsis Some Biochemical and Immunological Aspects of Host-parasite Relationships Consulting Editor: Thomas C. Cheng by : Thomas Clement Cheng
Download or read book Some Biochemical and Immunological Aspects of Host-parasite Relationships Consulting Editor: Thomas C. Cheng written by Thomas Clement Cheng and published by . This book was released on 1963 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pathobiology of Parasitic Protozoa: Dynamics and Dimensions by : Budhaditya Mukherjee
Download or read book Pathobiology of Parasitic Protozoa: Dynamics and Dimensions written by Budhaditya Mukherjee and published by Springer. This book was released on 2024-02-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the importance and significance of the systems approach in deciphering diverse aspects of host-parasite interactions in infection dynamics. It describes the complex issues and state-of-the-art progress in the infection biology of parasitic protozoa. The book explores the current concepts and paradigms of gene expression, metabolome, and immune remodeling in these diseases. The chapters encompass updates on the parasitic tropism, co-evolution, systemic responses in hosts, and translational approaches. It provides an overview of the parasite's efficient ways of exploiting host molecules and describes pathways for their survival, differentiation, and replication within the host cells. The book also delineates the role of inflammasomes and their activation in response to the protozoan parasite. The book discusses technological progress and machine learning-based modeling approaches to revisit parasitic infection from a non-conventional perspective. Collectively this book offers a comprehensive purview of concepts and paradigms in parasitic infection in the form of an updated yet discernible elucidation.
