Immunogenetics and Immunodeficiency

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Publisher : Springer Science & Business Media
ISBN 13 : 9401161356
Total Pages : 268 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Immunogenetics and Immunodeficiency by : B. Benacerraf

Download or read book Immunogenetics and Immunodeficiency written by B. Benacerraf and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of the genes which determine biological phenomena, and the study of the control they exert on these phenomena, has proven to be the most successful approach to a detailed understanding of their mechanism. The greatest advances in molecular biology have relied upon the application of the methodology of genetics to the elucidation of the fundamental processes of life at the cellular level. The same statement may be made concerning our understanding of im munological phenomena. The genetic approach has again proven extremely productive and has permitted us to identify many fundamental questions in im munobiology and to resolve some of them successfully. Among the problems with which the young discipline of immunogenetics has been concerned are the structural genes of the immunoglobulin chains. These genes have been iden tified by their control of allotypic antigenic determinants on the constant seg ment of H chains of different classes, on the constant segments of L chains and on both the constant and variable regions of rabbit H chains. These studies have provided the first evidence for the control of a single polypeptide chain by two distinct structural genes. Much has been learned concerning the genes coding the C and V regions of immunoglobulin chains (a) from the study of the inheritance of allotypic and idiotypic determinants on these chains discussed by Kunkel and Kindt and (b) from the analysis of the amino acid sequence in immunoglobulin chains from individual myeloma proteins and abnormal paraproteins, discussed by Frangione.

Human Immunogenetics

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Publisher : CRC Press
ISBN 13 : 1000103730
Total Pages : 849 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Human Immunogenetics by : S. D. Litwin

Download or read book Human Immunogenetics written by S. D. Litwin and published by CRC Press. This book was released on 2020-10-28 with total page 849 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delineating fundamental concepts of contemporary immunogenetics, this reference/text examines specific immunogenetic systems in terms of molecular biochemistry and immunophysiology. Covers material in diverse fields, including infectious diseases, cell biology, virology, molecular genetics. Comprise

Stiehm's Immune Deficiencies

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Publisher : Academic Press
ISBN 13 : 0124058604
Total Pages : 1157 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Stiehm's Immune Deficiencies by : Kathleen E. Sullivan

Download or read book Stiehm's Immune Deficiencies written by Kathleen E. Sullivan and published by Academic Press. This book was released on 2014-08-08 with total page 1157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stiehm's Immune Deficiencies focuses on immunodeficiencies in children and adults. This book covers the many advances in the study of immunodeficiency. Stiehm's Immune Deficiencies includes 62 chapters covering topics such as newly described syndromes, genetic diagnosis, molecular abnormalities, newborn screening, and current therapies. Provides practical guidance to practitioners dealing with the day-to-day issues of diagnosis and management of immune deficient patients Covers both clinical management and scientific advances in one place Includes newly described disorders in various periodic updates to maintain the breadth of the reference

Immunogenetics

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Publisher : BoD – Books on Demand
ISBN 13 : 1838803475
Total Pages : 98 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Immunogenetics by : Nima Rezaei

Download or read book Immunogenetics written by Nima Rezaei and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because genetic factors can impact immune responses, and immunogenetic associations serve as a predictor of disease development and as a biological indicator of disease progression, the study of immunogenetics is important to basic genetics and immunology, as well as to translational and individualized medicine.This book addresses a few but important issues on the subject of immunogenetics. First, it will review the role that human leukocyte antigen molecules play in the immune system and then take into consideration the effectiveness of Western blotting for the detection of immunologic proteins. The book will discuss studies on the immunogenetics of cancer and tuberculosis followed by implications for immunotherapy. Working separately, the book will also provide evidence that the application of immunogenetics has improved our understanding of brain and behavior disorders.

Immunogenetics: A Molecular and Clinical Overview

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Publisher : Academic Press
ISBN 13 : 0323903355
Total Pages : 412 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Immunogenetics: A Molecular and Clinical Overview by : Muneeb U. Rehman

Download or read book Immunogenetics: A Molecular and Clinical Overview written by Muneeb U. Rehman and published by Academic Press. This book was released on 2021-11-30 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. Contains exclusive information about research on immunogenetics from around the globe Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner

Primary and Secondary Immunodeficiency

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Publisher : Springer Nature
ISBN 13 : 3030571572
Total Pages : 409 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Primary and Secondary Immunodeficiency by : Jonathan A. Bernstein

Download or read book Primary and Secondary Immunodeficiency written by Jonathan A. Bernstein and published by Springer Nature. This book was released on 2021-01-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.

The Immunogenetics of Autoimmune Diseases

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Publisher : CRC Press
ISBN 13 : 9780849368974
Total Pages : 240 pages
Book Rating : 4.3/5 (689 download)

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Book Synopsis The Immunogenetics of Autoimmune Diseases by : Nadir R. Farid

Download or read book The Immunogenetics of Autoimmune Diseases written by Nadir R. Farid and published by CRC Press. This book was released on 1990-11-21 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex

Human Immunogenetics

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Publisher : Taylor & Francis US
ISBN 13 : 9780850663341
Total Pages : 232 pages
Book Rating : 4.6/5 (633 download)

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Book Synopsis Human Immunogenetics by : Jaime E. Bernal

Download or read book Human Immunogenetics written by Jaime E. Bernal and published by Taylor & Francis US. This book was released on 1986 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inborn Errors of Immunity

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Publisher : Academic Press
ISBN 13 : 0128231890
Total Pages : 396 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Inborn Errors of Immunity by : Asghar Aghamohammadi

Download or read book Inborn Errors of Immunity written by Asghar Aghamohammadi and published by Academic Press. This book was released on 2021-01-22 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laboratory findings. Presents valuable contribution of more than 40 expert chapter authors, from top centers spanning five continents, each in a specific PID field Covers various aspects of PID using updated clinical guidelines and standard stepwise pipelines Focuses on the latest developments in the molecular diagnosis and pathogenesis of diseases, with easy explanation and schematic representation of defective signaling pathways Includes dedicated sections for clinical features and immunological tests with carefully-curated figures of PID manifestations, imaging, and histological/pathological illustrations to create the first PID medial-color atlas Summarizes the updated conventional and specific treatments and follow-up notes for different PID diseases

Immune Deficiency

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Publisher : Springer Science & Business Media
ISBN 13 : 3642813623
Total Pages : 323 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Immune Deficiency by : M.D. Cooper

Download or read book Immune Deficiency written by M.D. Cooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of immune deficiency has become of special importance for two reasons. First, conditions with well defined defects in the immune system could be analyzed as "experiments of nature" in terms of finding out the accurate biological relevance of the defective link in the immune system. Secondly, the recognition of immune deficiency states has become important in order to provide the patients with the treatment necessary to remedy these defects. With regard to immune deficiency states in patients, these have been instrumental as "experiments of nature" in the revelation by Drs. Good and Cooper and their associates of the two-component structure of the immune system, a discovery which can be consi dered as a major breakthrough in the history of immunopathology. Today's research allows us to go far beyond this basic two component structure with the assessment of disorders affecting either cell to cell interactions or regarding subsets of lymphocyte populations. Furthermore, the association of immune deficiency with distinct enzymatic defects of purine metabolism is opening the door to the molecular level of immune deficiency. Dr. Cooper and Dr. Lawton have succeeded in obtaining the collaboration of the leaders in the field of immune deficiency. In view of the importance of their contributions in scientific and clinical terms, we decided to prepare a book version of the two issues of Seminars in Immunopathology devoted to this subject.

Primary Immunodeficiencies Worldwide

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Publisher : Frontiers Media SA
ISBN 13 : 2889635201
Total Pages : 224 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Primary Immunodeficiencies Worldwide by : Menno C. van Zelm

Download or read book Primary Immunodeficiencies Worldwide written by Menno C. van Zelm and published by Frontiers Media SA. This book was released on 2020-02-19 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Primary Immunodeficiency Diseases

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Publisher :
ISBN 13 : 0195389832
Total Pages : 930 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Primary Immunodeficiency Diseases by : Hans D. Ochs,

Download or read book Primary Immunodeficiency Diseases written by Hans D. Ochs, and published by . This book was released on 2013-09 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases.

The Immune System

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Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Immune System by : Gino Doria

Download or read book The Immune System written by Gino Doria and published by . This book was released on 1980 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Primary Immunodeficiency Diseases

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Publisher : Springer
ISBN 13 : 3662529092
Total Pages : 593 pages
Book Rating : 4.6/5 (625 download)

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Book Synopsis Primary Immunodeficiency Diseases by : Nima Rezaei

Download or read book Primary Immunodeficiency Diseases written by Nima Rezaei and published by Springer. This book was released on 2016-11-30 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of diagnosed cases of primary immunodeficiency diseases (PIDs) – a group of inborn disorders of the immune system – is growing rapidly, but misdiagnosis or late diagnosis still occurs in a significant number of patients, with serious consequences. This is the second edition of a practical reference textbook on PIDs that has been widely welcomed by scientists and clinicians from around the world. The new edition has been extensively revised to reflect advances in knowledge and includes various PIDs not previously covered. For each disease, information is provided on definition, etiology, clinical manifestations, diagnosis, and management. This book will represent an ideal resource for specialists when engaging in diagnosis, clinical decision-making, and treatment planning. It will also prove invaluable for doctors in training and other physicians and nurses who wish to learn more about PIDs.

Genetic Control of Immune Responsiveness

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Publisher : Academic Press
ISBN 13 : 0323148255
Total Pages : 490 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Genetic Control of Immune Responsiveness by : Hugh Mcdevitt

Download or read book Genetic Control of Immune Responsiveness written by Hugh Mcdevitt and published by Academic Press. This book was released on 2012-12-02 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Control of Immune Responsiveness: Relationship to Disease Susceptibility documents the proceedings of an international conference held at Brook Lodge, Augusta, Michigan, May 8-10, 1972. It brings together the detailed experimental evidence on the mechanism of action of specific immune response genes, and shows how the two major classes of immune response genes affect our understanding of basic immunology and antibody formation on the one hand, and of host factors determining disease susceptibility on the other. The book is organized into seven parts that correspond to the seven sessions of the conference. Part I presents a session on how the study of the genetic control of immune responses in guinea pigs and mice has contributed to the development of T cell immunology. Part II presents a session on genetic fine structure of the major (H-2) histocompatibility complex in the mouse. Part III presents a session dealing with the association between the production of homogeneous antibody, or of idiotypic antibody, and immunoglobulin allotypes. Part IV presents a session on the relationship between histocompatibility-linked and allotype-linked immune response genes and antigen-specific receptors on T and B cells. Part V presents a session on animal models of multigenic control of susceptibility to disease. Part VI presents a session on the associations between HL-A type and specific disease entities. Finally, Part VII provides a commentary on the ideas and concepts emerging from the three days of free-ranging discussion.

Chimpanzees in Biomedical and Behavioral Research

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Publisher : National Academies Press
ISBN 13 : 0309220424
Total Pages : 200 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Chimpanzees in Biomedical and Behavioral Research by : National Research Council

Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2011-12-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.

Immunology in the Twentieth Century

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Publisher : Academic Press
ISBN 13 : 0128161469
Total Pages : 92 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Immunology in the Twentieth Century by : Domenico Ribatti

Download or read book Immunology in the Twentieth Century written by Domenico Ribatti and published by Academic Press. This book was released on 2018-04-24 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology in the Twentieth Century: From Basic Science to Clinical Application grew out of common knowledge that those who survived many of the common infectious diseases rarely contracted the same disease again. This book charts the historical development of this vital branch of medicine in a concise volume, covering both the basic science involved and the clinical applications. Immunology as a distinctive subject developed in the mid-twentieth century as researchers started to understand how the adaptive immune system aids the defense against pathogens. The subject has grown in importance and diversified into specialist fields, such as immunohistochemistry, immunogenetics and immunopathology. Provides a concise overhead of the history of immunology and its applications in medicine Includes a discussion of the scientists who were pioneers in landmark discoveries in immunology Summarizes the clinical applications of major discoveries