Immunobiology Of Proteins And Peptides I

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Immunobiology of Proteins and Peptides · I

Author : M. Zouhair Atassi
Publisher : Springer Science & Business Media
ISBN 13 : 1461588588
Total Pages : 501 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Immunobiology of Proteins and Peptides · I by : M. Zouhair Atassi

Download or read book Immunobiology of Proteins and Peptides · I written by M. Zouhair Atassi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the central questions in immunology is the understanding in molecular terms of antigen-antibody interactions and of the cellu lar recognition of antigens. It is hoped that this understanding will extend eventually to the immunobiological basis of host defense to infectious agents and of tissue damage or deranged cell functions which stem from these reactions. A variety of natural and artificial substances have been used as models for these studies. Emphasis was placed upon substances of known and relatively uncomplicated chemical structures. These included polysaccharides, amino acid polymers, nu cleic acids and haptens. On the other hand. until recently there has been very little information on protein antigens. The complexity of these molecules posed an immense chemical obstacle to precise immuno chemical analysis. Indeed, it is this difficulty with proteins that spurred the synthesis and immunological studies of amino acid poly mers. The control and normal regulation of the immune system at the cellular-molecular interface and the great majority of antigens asso ciated with immune disorders are attributed to protein molecules. In the last few years great advances have been made in the analysis and synthesis of the antigenic sites of some proteins. The entire antigenic structures of myoglobin and lysozyme and the partial anti genic structures of several other proteins have been determined. Moreover, in the past seven years several biological responses resulting from the reactions of proteins and their peptides with cells of the immune system were described.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Janeway's Immunobiology

Author : Kenneth Murphy
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Structural Biology in Immunology

Author : Chaim Putterman
Publisher : Academic Press
ISBN 13 : 0128033703
Total Pages : 192 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Structural Biology in Immunology by : Chaim Putterman

Download or read book Structural Biology in Immunology written by Chaim Putterman and published by Academic Press. This book was released on 2018-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. - Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules - Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship - Features a collaborative editorial effort, involving clinical immunologists and structural biologists - Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology - Gives interested parties a bridge to learn about computer modeling and structure based design principles

Peptide and Protein Delivery

Author : Chris Van Der Walle
Publisher : Academic Press
ISBN 13 : 0123849365
Total Pages : 381 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Peptide and Protein Delivery by : Chris Van Der Walle

Download or read book Peptide and Protein Delivery written by Chris Van Der Walle and published by Academic Press. This book was released on 2011-05-12 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. - Discusses the most recent data, ideas and concepts - Presents case studies and an industrial perspective - Details information from the molecular level to bioprocessing - Thought provoking, for the novice to the specialist - Timely, for today's biopharmaceuticals market

Peptide Antibodies

Author : Gunnar Houen
Publisher : Humana
ISBN 13 : 9781493929986
Total Pages : 0 pages
Book Rating : 4.9/5 (299 download)

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Book Synopsis Peptide Antibodies by : Gunnar Houen

Download or read book Peptide Antibodies written by Gunnar Houen and published by Humana. This book was released on 2015-10-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive volume covers basic and advanced aspects of peptide antibody production, characterization and uses. Although peptide antibodies have been available for many years, they continue to be a field of active research and method development. For example, peptide antibodies which are dependent on specific posttranslational modifications are of great interest, such as phosphorylation, citrullination and others, while different forms of recombinant peptide antibodies are gaining interest, notably nanobodies, single chain antibodies, TCR-like antibodies, among others. Within this volume, those areas are covered, as well as several technical and scientific advances: solid phase peptide synthesis, peptide carrier conjugation and immunization, genomics, transcriptomics, proteomics and elucidation of the molecular basis of antigen presentation and recognition by dendritic cells, macrophages, B cells and T cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Peptide Antibodies: Methods and Protocols serves as an ideal reference for researchers exploring this vital and expansive area of study.

Immunoinformatics

Author : Christian Schönbach
Publisher : Springer Science & Business Media
ISBN 13 : 0387729682
Total Pages : 216 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Immunoinformatics by : Christian Schönbach

Download or read book Immunoinformatics written by Christian Schönbach and published by Springer Science & Business Media. This book was released on 2007-11-21 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

Bioinformatics

Author : Venkatarajan Mathura
Publisher : Springer Science & Business Media
ISBN 13 : 0387848703
Total Pages : 196 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Bioinformatics by : Venkatarajan Mathura

Download or read book Bioinformatics written by Venkatarajan Mathura and published by Springer Science & Business Media. This book was released on 2008-10-11 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics is an evolving field that is gaining popularity due to genomics, proteomics and other high-throughput biological methods. The function of bioinformatic scientists includes biological data storage, retrieval and in silico analysis of the results from large-scale experiments. This requires a grasp of knowledge mining algorithms, a thorough understanding of biological knowledge base, and the logical relationship of entities that describe a process or the system. Bioinformatics researchers are required to be trained in multidisciplinary fields of biology, mathematics and computer science. Currently the requirements are satisfied by ad hoc researchers who have specific skills in biology or mathematics/computer science. But the learning curve is steep and the time required to communicate using domain specific terms is becoming a major bottle neck in scientific productivity. This workbook provides hands-on experience which has been lacking for qualified bioinformatics researchers.

Protein and Peptide Mass Spectrometry in Drug Discovery

Author : Michael L. Gross
Publisher : John Wiley & Sons
ISBN 13 : 1118116542
Total Pages : 407 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Protein and Peptide Mass Spectrometry in Drug Discovery by : Michael L. Gross

Download or read book Protein and Peptide Mass Spectrometry in Drug Discovery written by Michael L. Gross and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.

Immunogenicity of Proteins Used as Therapeutics

Author : Amy Rosenberg
Publisher : Frontiers Media SA
ISBN 13 : 2889662888
Total Pages : 328 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Immunogenicity of Proteins Used as Therapeutics by : Amy Rosenberg

Download or read book Immunogenicity of Proteins Used as Therapeutics written by Amy Rosenberg and published by Frontiers Media SA. This book was released on 2020-12-28 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Susan Richards is an employee of Sanofi and owns stock in the corporation. Topic Editor Bernard Maillere declares economic support from pharmaceutical companies (Novartis, Sanofi, and UCB) in the frame of collaborations aiming to evaluate the recognition by human T cells of therapeutic proteins and antibodies.

Milk and Dairy Products as Functional Foods

Author : Ara Kanekanian
Publisher : John Wiley & Sons
ISBN 13 : 1118635086
Total Pages : 472 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Milk and Dairy Products as Functional Foods by : Ara Kanekanian

Download or read book Milk and Dairy Products as Functional Foods written by Ara Kanekanian and published by John Wiley & Sons. This book was released on 2014-04-09 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: There continues to be strong interest within the food industry in developing new products which offer functional health benefits to the consumer. The premium prices that can be charged make these added-value products lucrative for manufacturers, and they are also commercially popular. Dairy foods are central to this sector: they are good delivery systems for functional foods (yoghurts, milk drinks, spreads) and are also rich in compounds which can be extracted and used as functional ingredients in other food types. Milk and Dairy Products as Functional Foods draws together a wealth of information regarding the functional health benefits of milk and dairy products. It examines the physiological role and the claimed health effects of dairy constituents such as proteins, bioactive peptides, conjugated linoleic acid (CLA), omega 3 fatty acids vitamin D and calcium. These constituents have been shown to be, for example, anticarcinogenic, anti-inflammatory, antihypertensive, hypocholesterolemic, immune-modulating and antimicrobial. This book examines the evidence for these claims, and investigates practical approaches for utilising these attributes. The book is aimed at dairy scientists and technologists in industry and academia, general food scientists and technologists, microbiologists and nutritionists together with all those involved in the formulation and production of functional food products.

Biopolymer Science for Proteins and Peptides

Author : Keiji Numata
Publisher : Elsevier
ISBN 13 : 0128205563
Total Pages : 310 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Biopolymer Science for Proteins and Peptides by : Keiji Numata

Download or read book Biopolymer Science for Proteins and Peptides written by Keiji Numata and published by Elsevier. This book was released on 2021-08-14 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopolymer Science for Proteins and Peptides introduces all aspects of natural polymers based on structural proteins and peptides, presenting synthesis, structure, properties, proteins, materials design, and applications. The book begins by presenting the core concepts of polypeptide and protein materials, before discussing synthesis and structure in detail. The next part of the book describes physical properties, biological properties, and issues surrounding stability. Subsequent chapters offer in-depth coverage of both natural and structural protein sources, including collagen, silk, elastin, resilin, keratin, foot protein, and reflectin, and the materials that can be designed from them, such as films, fibers, textiles, microparticles, sponges and scaffolds, nanomaterials, blends, and composites. These materials are also analyzed against the available synthetic polymers. Finally, the text explores current applications and potential future developments. This is an essential resource for researchers and advanced students across a range of disciplines, including biopolymers, structural proteins, polymer science, materials science, biomaterials, biology, biotechnology, chemistry, engineering, and pharmaceutical science. In an industry setting, this is of great interest to scientists and R&D professionals working in industries with an interest in bio-based polymers for advanced applications. - Explains how biopolymers from structural proteins and peptides can be developed into materials, such as films, fibers, textiles, microparticles, sponges and scaffolds, nanomaterials, blends, and polymer composites - Provides the reader a solid understanding of the structure, synthesis, and properties - Guides the reader from sources, including collagen, silk, elastin, resilin, keratin, and reflectin, to material design and cutting-edge applications

Human Herpesviruses

Author : Ann Arvin
Publisher : Cambridge University Press
ISBN 13 : 1139461648
Total Pages : 1325 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Human Herpesviruses by : Ann Arvin

Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Sequences of Proteins of Immunological Interest

Author : Elvin A. Kabat
Publisher : DIANE Publishing
ISBN 13 : 094137565X
Total Pages : 2710 pages
Book Rating : 4.9/5 (413 download)

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Book Synopsis Sequences of Proteins of Immunological Interest by : Elvin A. Kabat

Download or read book Sequences of Proteins of Immunological Interest written by Elvin A. Kabat and published by DIANE Publishing. This book was released on 1992-06 with total page 2710 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major compilation & presentation of amino & DNA sequences produced under the direction of Dr. Elvin A. Kabat, who received a National Medal of Science in 1991, for his "seminal contributions in the field of immunology". Contains new & expanded sections on T-cell reactors, §2-microglobulins, major histocompatibiltiy antigens, complement, thymopoietin, integrins, & post-gamma globulin. Covers 9,000 sequences, plus 3 indices: index of proteins, index of antibody specificities & index of references. Best seller!!

Biological Barriers to Protein Delivery

Author : Kenneth L. Andus
Publisher : Springer Science & Business Media
ISBN 13 : 1461528984
Total Pages : 507 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Biological Barriers to Protein Delivery by : Kenneth L. Andus

Download or read book Biological Barriers to Protein Delivery written by Kenneth L. Andus and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

Delivery Technologies for Biopharmaceuticals

Author : Lene Jorgensen
Publisher : John Wiley & Sons
ISBN 13 : 0470688408
Total Pages : 442 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Delivery Technologies for Biopharmaceuticals by : Lene Jorgensen

Download or read book Delivery Technologies for Biopharmaceuticals written by Lene Jorgensen and published by John Wiley & Sons. This book was released on 2009-10-23 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability. Therefore researchers are developing a range of new delivery technologies and materials to enable these new drugs to be delivered intact to their target sites. Delivery Technologies for Biopharmaceuticals describes strategies to overcome the main barriers for successful delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines related to the site of administration and the target site. Many of the approaches described are reported in formulations in current clinical trials as well as in marketed products. Contents include: challenges in delivery of biopharmaceuticals novel formulation approaches for peptide and protein injectables non-viral chemical vectors and viral technology for delivery of nucleic acid based drugs immune response, adjuvants and delivery systems for vaccines several examples of delivery systems for different biopharmaceuticals a critical assessment of delivery technologies for biopharmaceuticals Delivery Technologies for Biopharmaceuticals is an essential single-volume introduction to the technologies used by researchers to ensure efficient delivery of this exciting new class of drugs. It will be of value to researchers and students working in drug delivery, formulation, biopharmaceuticals, medicinal chemistry, and new materials development.

Milk and Dairy Products in Human Nutrition

Author : Young W. Park
Publisher : John Wiley & Sons
ISBN 13 : 1118534204
Total Pages : 1063 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Milk and Dairy Products in Human Nutrition by : Young W. Park

Download or read book Milk and Dairy Products in Human Nutrition written by Young W. Park and published by John Wiley & Sons. This book was released on 2013-04-09 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: Milk is nature’s most complete food, and dairy products are considered to be the most nutritious foods of all. The traditional view of the role of milk has been greatly expanded in recent years beyond the horizon of nutritional subsistence of infants: it is now recognized to be more than a source of nutrients for the healthy growth of children and nourishment of adult humans. Alongside its major proteins (casein and whey), milk contains biologically active compounds, which have important physiological and biochemical functions and significant impacts upon human metabolism, nutrition and health. Many of these compounds have been proven to have beneficial effects on human nutrition and health. This comprehensive reference is the first to address such a wide range of topics related to milk production and human health, including: mammary secretion, production, sanitation, quality standards and chemistry, as well as nutrition, milk allergies, lactose intolerance, and the bioactive and therapeutic compounds found in milk. In addition to cow’s milk, the book also covers the milk of non-bovine dairy species which is of economic importance around the world. The Editors have assembled a team of internationally renowned experts to contribute to this exhaustive volume which will be essential reading for dairy scientists, nutritionists, food scientists, allergy specialists and health professionals.