Immune Rebalancing

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Author :
Publisher : Academic Press
ISBN 13 : 0128033363
Total Pages : 298 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Immune Rebalancing by : Diana Boraschi

Download or read book Immune Rebalancing written by Diana Boraschi and published by Academic Press. This book was released on 2016-01-25 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine. Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc. Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches Provides information on the new strategies for drug development in this field Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader’s strategy for addressing therapeutic immune modulations

The Immunotype Breakthrough

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Author :
Publisher : Hachette UK
ISBN 13 : 1398706035
Total Pages : 304 pages
Book Rating : 4.3/5 (987 download)

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Book Synopsis The Immunotype Breakthrough by : Heather Moday

Download or read book The Immunotype Breakthrough written by Heather Moday and published by Hachette UK. This book was released on 2021-12-23 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'In an era of heightened awareness of our immune system, the threat of pandemics, the rise of autoimmunity, and the revelatory new science that everything from heart disease to cancer, Alzheimer's to autism, and depression to diabetes is linked to disordered immune function and inflammation, The Immunotype Breakthrough is the most important guide available today to understand and optimise our immune function. It is an essential roadmap for anyone with an immune system (essentially everyone!), anyone looking to optimise their health and avoid today's modern plague - inflammation.' DR MARK HYMAN, New York Times-bestselling author of The Pegan Diet. 'The immune system has been overlooked and misunderstood for far too long. In The Immunotype Breakthrough, Dr Moday gives us a glimpse into her speciality and explains the recent research in a way that we can all understand. Best of all, she gives us action steps we can each take to prioritise our immune system to elevate our overall health.' DR WILL COLE, New York Times-bestselling author of Intuitive Fasting 'This is a must-read for anyone who has experienced the pitfalls of conventional medicine and is ready to balance their immune system for optimal health.' DR AMY MYERS, author of The Autoimmune Solution and Thyroid Connection 'A revolutionary book from one of the best immunity experts around. The Immunotype Breakthrough explains the latest science on immunity, and offers unique, customisable advice to help you balance your immune system. A must-read for anyone interested in living a long and healthy life." JASON WACHOB, Founder & Co-CEO of mindbodygreen.com To most of us, the immune system is a mysterious and complex network of cells, receptors, and messengers that we only notice when it goes awry. But our immune response, or lack of, affects nearly every aspect of our bodies and our health. Much has been made of 'boosting' immunity, but what exactly does that mean? And what if boosting isn't really what our immune systems need? In The Immunotype Breakthrough, functional medicine doctor and immunity specialist Dr Heather Moday explains that, for the most part, what our immune systems truly need is not boosting, but balancing. She identifies four distinct immunotypes, and helps you find yours: Smouldering: too much inflammation, resulting in diabetes, dementia, heart disease Misguided: an immune system which attacks your own cells and organs, causing autoimmune diseases Hyperactive: overreactive to harmless substances, causing allergies Weak: an immune system that doesn't react fast or effectively enough, causing frequent colds, flu or bronchitis Drawing on a wealth of cutting-edge research, Dr Moday explains that our immune systems are fluid and significantly influenced by our behaviours, diet, habits, and environment. By identifying your personal immunotype, and implementing Dr Moday's Immune Restoration Plan, you can make focused, individualised lifestyle changes to bring your immune system back into balance. With interactive quizzes to help readers zero in on their own specific needs, The Immunotype Breakthrough is a revolutionary programme that will lead to holistic health, vitality, and longevity for everyone.

Calming Inflammation

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Author :
Publisher : Independently Published
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.3/5 (247 download)

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Book Synopsis Calming Inflammation by : Virgie W Miller

Download or read book Calming Inflammation written by Virgie W Miller and published by Independently Published. This book was released on 2024-05-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With "Calming Inflammation: 7 Tested Techniques for Immune Balance, Gut Wellness, Stress Reduction, and Optimal Living," take the first steps toward robust health. This indispensable manual has been painstakingly written to assist you in accurately and easily navigating the complexity of inflammation. Why Select "Inflammation Calming"? Expertly Researched: This book provides a wealth of factual and useful information, drawing on the most recent scientific findings. Holistic Approach: Immerse yourself in a multifaceted wellness plan that supports gut health, balances your immune system, and soothes your mind. Useful Solutions: Armed with seven tried-and-true methods, you'll be ready to take on inflammation head-on and enjoy a more contented and balanced existence. Inside, You'll Learn: Immune System Insights: Become proficient at adjusting your body's defense processes so that they function as a tool rather than against you. The Secrets of Gut Health: Discover the potential of your digestive system as the foundation of your general health. Stress-Busting Techniques: Develop the skill of stress reduction to lessen inflammation and improve your everyday tranquility. Nutritional Wisdom: Try these delectable, flavor-preserving meals to embrace an anti-inflammatory diet. Movement for Vitality: Incorporate fun, inflammation-reducing physical activity into your daily routine. Holistic Healing: Investigate complementary therapies that are in harmony with the inherent healing mechanisms of your body. Your Benefits: Empowerment: Gain a thorough understanding of health issues and take charge of your well-being with this knowledge. Flexibility: Regardless of where you are beginning from, find solutions that work well for you. Act Now Don't allow inflammation to limit the possibilities in your life. "Calming Inflammation" is the roadmap to a more promising and health-conscious future. Get your copy right away to start your journey to a life full of vitality, balance, and health!

Radiation and the Immune System: Current Knowledge and Future Perspectives

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889454746
Total Pages : 283 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Radiation and the Immune System: Current Knowledge and Future Perspectives by : Katalin Lumniczky

Download or read book Radiation and the Immune System: Current Knowledge and Future Perspectives written by Katalin Lumniczky and published by Frontiers Media SA. This book was released on 2018-05-03 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

[HIV] disease resulting in infectious and parasitic diseases

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Author :
Publisher : Dr. Spineanu Eugenia
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4./5 ( download)

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Book Synopsis [HIV] disease resulting in infectious and parasitic diseases by : Dr. Spineanu Eugenia

Download or read book [HIV] disease resulting in infectious and parasitic diseases written by Dr. Spineanu Eugenia and published by Dr. Spineanu Eugenia. This book was released on with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dive into the comprehensive world of HIV/AIDS with 'Comprehensive Insights into HIV/AIDS: From Pathogenesis to Holistic Health.' This treatise delves deep into the multifaceted realm of HIV/AIDS, offering an extensive exploration from the fundamental virology and immunological responses to the intricate pathogenesis of the virus. Unravel the global epidemiology, transmission modes, and viral structure, gaining a nuanced understanding of this complex disease. Beyond the scientific intricacies, this treatise broadens the horizon, delving into HIV testing methodologies, clinical stages, and associated complications like opportunistic infections and malignancies. It elucidates the interplay between HIV and the immune system, discussing CD4 T-cell depletion and the impact on immune function, while delving into the role of antiretroviral therapy (ART) in immune restoration. But this treatise doesn't stop at the medical spectrum. It embraces a holistic approach, exploring the psychological and societal dimensions of HIV/AIDS. From stigma and discrimination to psychosocial support, prevention strategies, and ethical considerations, it emphasizes the importance of mental well-being, education, and ethical frameworks in combating this global challenge. Experience a comprehensive journey, navigating through the landscape of HIV/AIDS research, treatment, ethical considerations, and societal implications. This treatise is a definitive guide, merging scientific depth with a holistic perspective, catering to healthcare professionals, researchers, students, and anyone passionate about understanding and addressing the multifaceted aspects of HIV/AIDS.

Pediatric Chiropractic

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1975163133
Total Pages : 4018 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Pediatric Chiropractic by : Claudia A. Anrig

Download or read book Pediatric Chiropractic written by Claudia A. Anrig and published by Lippincott Williams & Wilkins. This book was released on 2022-02-12 with total page 4018 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-awaited third edition of Pediatric Chiropractic takes the valuable second edition to a whole new level, offering new chapters, full-color photos, illustrations, and tables to provide the family wellness chiropractor and the student of chiropractic a valuable reference manual covering all aspects of care for the pediatric and prenatal populations. Internationally recognized authorities Claudia Anrig, DC and Gregory Plaugher, DC have invited the leaders in their fields to contribute to this precedent-setting textbook and now offer even more valuable information for the practitioner.

The Road to Immunity

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Author :
Publisher : Simon and Schuster
ISBN 13 : 0671545078
Total Pages : 452 pages
Book Rating : 4.6/5 (715 download)

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Book Synopsis The Road to Immunity by : Kenneth Bock

Download or read book The Road to Immunity written by Kenneth Bock and published by Simon and Schuster. This book was released on 1997-10 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive guide, Dr. Bock shares his cutting-edge approach that tells readers exactly how to boost their immune systems to their maximum effectiveness. Grounded in solid medicine, but including unconventional therapies, his book shows readers how to evaluate their individual needs, then address them with tailor-made diet, exercise, supplement, and relaxation therapies.

A year in review: Discussions in autoimmune and autoinflammatory disorders

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832519385
Total Pages : 173 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis A year in review: Discussions in autoimmune and autoinflammatory disorders by : Raphaela Goldbach-Mansky

Download or read book A year in review: Discussions in autoimmune and autoinflammatory disorders written by Raphaela Goldbach-Mansky and published by Frontiers Media SA. This book was released on 2023-03-31 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Avian Immunology

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Author :
Publisher : Academic Press
ISBN 13 : 0123972728
Total Pages : 456 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Avian Immunology by : Karel A. Schat

Download or read book Avian Immunology written by Karel A. Schat and published by Academic Press. This book was released on 2012-12-02 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research

ADVANCED TREATMENT FOR DUCHENNE MUSCULAR DYSTROPHY: APOMETRY, NLP, REGRESSION AND HYPNOSIS

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Author :
Publisher : Edenilson Brandl
ISBN 13 :
Total Pages : 712 pages
Book Rating : 4./5 ( download)

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Book Synopsis ADVANCED TREATMENT FOR DUCHENNE MUSCULAR DYSTROPHY: APOMETRY, NLP, REGRESSION AND HYPNOSIS by : Thor Otto Alexsander

Download or read book ADVANCED TREATMENT FOR DUCHENNE MUSCULAR DYSTROPHY: APOMETRY, NLP, REGRESSION AND HYPNOSIS written by Thor Otto Alexsander and published by Edenilson Brandl. This book was released on with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the realm of healthcare and holistic well-being, innovation is a constant driving force. The journey to alleviate and potentially cure the complexities of conditions like Duchenne Muscular Dystrophy (DMD) requires an open-minded exploration of alternative healing methodologies. This book, "Advanced Treatment for Duchenne Muscular Dystrophy: Apometry, NLP, Regression, and Hypnosis," emerges as a culmination of such exploration. DMD presents intricate challenges that often leave individuals and families seeking answers beyond the conventional medical approaches. It is within this quest for holistic solutions that the realms of Apometry, Neuro-Linguistic Programming (NLP), Regression, and Hypnosis come to light. These disciplines, often considered unconventional, offer a unique perspective on healing—one that encompasses not only the physical body but also delves into the intricacies of the mind, spirit, and consciousness. Unveiling the Journey This book invites you to embark on a journey that combines ancient wisdom with cutting-edge techniques. It delves into the heart of Apometry—a practice that bridges the spiritual and physical planes to enact profound healing. It explores the power of NLP to reprogram thought patterns and behaviors, facilitating a shift towards well-being. Regression techniques offer a portal to explore past experiences, potentially unearthing hidden sources of ailments. Hypnosis, a state of focused awareness, opens doors to the subconscious mind, where transformation can occur on a deep level. A Multifaceted Approach Each chapter in this book serves as a gateway to a realm of healing. From the initial understanding of Apometry's capabilities to the intricate world of spiritual healing commands, from preparing the individual for Apometry sessions to addressing the uncharted territory of intergalactic influences—this book navigates a spectrum of ideas, possibilities, and practices. Beyond Boundaries As the author, my intention is to provide an expansive perspective on healing that transcends conventional boundaries. While the primary focus is on addressing Duchenne Muscular Dystrophy, the principles and techniques presented here have the potential to ripple into broader applications. The intersections with genetics, parapsychology, consciousness, and more showcase the interconnectedness of various realms of knowledge. A Call for Exploration I invite you, the reader, to approach this book with curiosity and an open heart. The ideas presented here are not meant to replace medical guidance but rather to complement it. In the face of challenges like DMD, exploring diverse approaches is a testament to our dedication to healing and progress. May this book serve as a source of insight, inspiration, and empowerment on your journey towards advanced treatment for Duchenne Muscular Dystrophy and, by extension, towards holistic well-being and growth.

The Great Rebalancing

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Author :
Publisher : Princeton University Press
ISBN 13 : 0691163626
Total Pages : 256 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis The Great Rebalancing by : Michael Pettis

Download or read book The Great Rebalancing written by Michael Pettis and published by Princeton University Press. This book was released on 2014-10-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: How trade imbalances spurred on the global financial crisis and why we aren't out of trouble yet China's economic growth is sputtering, the Euro is under threat, and the United States is combating serious trade disadvantages. Another Great Depression? Not quite. Noted economist and China expert Michael Pettis argues instead that we are undergoing a critical rebalancing of the world economies. Debunking popular misconceptions, Pettis shows that severe trade imbalances spurred on the recent financial crisis and were the result of unfortunate policies that distorted the savings and consumption patterns of certain nations. Pettis examines the reasons behind these destabilizing policies, and he predicts severe economic dislocations that will have long-lasting effects. Demonstrating how economic policies can carry negative repercussions the world over, The Great Rebalancing sheds urgent light on our globally linked economic future.

Textbook of Pediatric Rheumatology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437735967
Total Pages : 817 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Textbook of Pediatric Rheumatology E-Book by : James T. Cassidy

Download or read book Textbook of Pediatric Rheumatology E-Book written by James T. Cassidy and published by Elsevier Health Sciences. This book was released on 2010-10-15 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Pediatric Rheumatology examines the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents, detailing the presentation, differential diagnosis, course, management, and prognosis of every major condition. Drs. James T. Cassidy, Ross E. Petty, Ronald M. Laxer, and Carol B. Lindsley discuss recent developments in diagnosis, treatment, genetics, immunology, imaging, and more. Diagnose and treat effectively through exhaustive reviews of the complex symptoms and signs and lab abnormalities that characterize these clinical disorders. Choose treatment protocols based on the best scientific evidence available today. Apply the knowledge and experience of the leading experts in the field. Keep current with coverage of new topics including macrophage activation syndrome, pediatric sarcoidosis, uveitis, imaging, and occupational and physical therapy. Tap into detailed discussions of recent advances in the field, new research on the immunologic mechanisms of inflammatory disease, and new developments on biologic treatments for arthritis in ten new chapters. Master complex concepts and key techniques with a full-color design and full-color illustrations.

Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889635821
Total Pages : 139 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation by : Liwu Li

Download or read book Innate Immunity Programming and Memory in Resolving and Non-Resolving Inflammation written by Liwu Li and published by Frontiers Media SA. This book was released on 2020-03-18 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Immunology and Immunotherapy

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Author :
Publisher : Academic Press
ISBN 13 : 012823637X
Total Pages : 550 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Cancer Immunology and Immunotherapy by : Mansoor M. Amiji

Download or read book Cancer Immunology and Immunotherapy written by Mansoor M. Amiji and published by Academic Press. This book was released on 2021-08-18 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO

The role of monocytes/macrophages in autoimmunity and autoinflammation

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832509487
Total Pages : 222 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The role of monocytes/macrophages in autoimmunity and autoinflammation by : Atsushi Kawakami

Download or read book The role of monocytes/macrophages in autoimmunity and autoinflammation written by Atsushi Kawakami and published by Frontiers Media SA. This book was released on 2022-12-22 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxic Overload

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Author :
Publisher : Penguin
ISBN 13 : 9781583332252
Total Pages : 302 pages
Book Rating : 4.3/5 (322 download)

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Book Synopsis Toxic Overload by : Paula Baillie-Hamilton

Download or read book Toxic Overload written by Paula Baillie-Hamilton and published by Penguin. This book was released on 2005 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: An environmental health specialist reveals how exposure to everyday products can result in toxic buildups in the body, outlining a seven-day program that encompasses a body-cleaning diet and supplement regimen, home detoxification tips, and recommendations for chemical-free products. By the author of The Body Restoration Plan.

Cancer Immunotherapy & Immuno-monitoring: Mechanism, Treatment, Diagnosis, and Emerging Tools

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Author :
Publisher : Frontiers E-books
ISBN 13 : 2889193802
Total Pages : 98 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Cancer Immunotherapy & Immuno-monitoring: Mechanism, Treatment, Diagnosis, and Emerging Tools by : Chao Ma

Download or read book Cancer Immunotherapy & Immuno-monitoring: Mechanism, Treatment, Diagnosis, and Emerging Tools written by Chao Ma and published by Frontiers E-books. This book was released on 2014-12-16 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, significant progresses have taken place in the field of cancer immunotherapy. Tumor-targeting immunotherapies are being developed for most human cancers, including melanoma, prostate cancer, glioblastoma, sarcoma, lung carcinoma and hepatocellular carcinoma. The FDA has approved multiple molecular immunotherapeutics, such as Ipilimumab; cellular immunotherapies (e.g. adoptive cell transfer) are being tested in phase II/III clinical trials. Immunotherapetics has evolved into a sophisticated field: Multimodal therapeutic regimens are administrated to induce focused responses, curtail side- effects and improve therapeutic efficacy. The lack of effective clinical assessment tools remains a major challenge. Because of the intricacy of antitumor response, it is essential to scrutinize individual tumor-targeting immune cells and their functions at the finest details – molecules. In this regard, flow cytometry analysis modernized hematology and allows characterization of surface molecular signature on individual cells. More recently, microchip technologies and new variations of cytometry have enormously expanded the spectrum, throughout and multiplexity of single cell analysis. Nowadays, tens of millions of readouts can be generated through the course of a cancer immunotherapy to monitor the abundance, phenotype and a myriad of effector functions of single immune cells. At the same time, big data analytics and data mining methodologies have been adapted to achieve sensible diagnostic interpretations. Such a marriage of technology and analytics opens the door for informative point-of-care assessment of therapeutic efficacy and ensures timely therapeutic decisions. The new generation of personalized clinical diagnostics will revolutionize healthcare in the years to come.