The Emperor of All Maladies

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Metal Fatigue: Effects of Small Defects and Nonmetallic Inclusions

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Publisher : Elsevier
ISBN 13 : 0080496563
Total Pages : 384 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Metal Fatigue: Effects of Small Defects and Nonmetallic Inclusions by : Yukitaka Murakami

Download or read book Metal Fatigue: Effects of Small Defects and Nonmetallic Inclusions written by Yukitaka Murakami and published by Elsevier. This book was released on 2002-04-29 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal fatigue is an essential consideration for engineers and researchers who are looking at factors that cause metals to fail through stress, corrosion, etc. This is an English translation of a book originally published in Japan in 1993, with an additional two chapters on the fatigue failure of steels and the effect of surface roughness on fatigue strength. The methodology is based on important and reliable results and may be usefully applied to other fatigue problems not directly treated in this book.

Materials and Processes

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Publisher : Springer
ISBN 13 : 3319233629
Total Pages : 677 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Materials and Processes by : Barrie D. Dunn

Download or read book Materials and Processes written by Barrie D. Dunn and published by Springer. This book was released on 2015-12-29 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to assist scientists and engineers select the ideal material or manufacturing process for particular applications; these could cover a wide range of fields, from light-weight structures to electronic hardware. The book will help in problem solving as it also presents more than 100 case studies and failure investigations from the space sector that can, by analogy, be applied to other industries. Difficult-to-find material data is included for reference. The sciences of metallic (primarily) and organic materials presented throughout the book demonstrate how they can be applied as an integral part of spacecraft product assurance schemes, which involve quality, material and processes evaluations, and the selection of mechanical and component parts. In this successor edition, which has been revised and updated, engineering problems associated with critical spacecraft hardware and the space environment are highlighted by over 500 illustrations including micrographs and fractographs. Space hardware captured by astronauts and returned to Earth from long durations in space are examined. Information detailed in the Handbook is applicable to general terrestrial applications including consumer electronics as well as high reliability systems associated with aeronautics, medical equipment and ground transportation. This Handbook is also directed to those involved in maximizing the relia bility of new materials and processes for space technology and space engineering. It will be invaluable to engineers concerned with the construction of advanced structures or mechanical and electronic sub-systems.

Quasibrittle Fracture Mechanics and Size Effect

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Author :
Publisher : Oxford University Press
ISBN 13 : 0192846248
Total Pages : 332 pages
Book Rating : 4.1/5 (928 download)

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Book Synopsis Quasibrittle Fracture Mechanics and Size Effect by : Jia-Liang Le

Download or read book Quasibrittle Fracture Mechanics and Size Effect written by Jia-Liang Le and published by Oxford University Press. This book was released on 2021-11-19 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many modern engineering structures are composed of brittle heterogenous, or quasibrittle, materials. These include concrete, composites, tough ceramics, rocks, cold asphalt mixtures, and many brittle materials at the microscale. Understanding the failure behavior of these materials is of paramount importance for improving the resilience and sustainability of various engineering structures including civil infrastructure, aircraft, ships, military armors, and microelectronic devices. Designed for graduate and upper-level undergraduate university courses, this textbook provides a comprehensive treatment of quasibrittle fracture mechanics. It includes a concise but rigorous examination of linear elastic fracture mechanics, which is the foundation of all fracture mechanics. It also covers the fundamental concepts of nonlinear fracture mechanics, and introduces more advanced concepts such as triaxial stress state in the fracture process zone, nonlocal continuum models, and discrete computational models. Finally, the book features extensive discussion of the various practical applications of quasibrittle fracture mechanics across different structures and engineering disciplines, and throughout includes exercises and problems for students to test their understanding.

Automated Solution of Differential Equations by the Finite Element Method

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Publisher : Springer Science & Business Media
ISBN 13 : 3642230997
Total Pages : 723 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Automated Solution of Differential Equations by the Finite Element Method by : Anders Logg

Download or read book Automated Solution of Differential Equations by the Finite Element Method written by Anders Logg and published by Springer Science & Business Media. This book was released on 2012-02-24 with total page 723 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a tutorial written by researchers and developers behind the FEniCS Project and explores an advanced, expressive approach to the development of mathematical software. The presentation spans mathematical background, software design and the use of FEniCS in applications. Theoretical aspects are complemented with computer code which is available as free/open source software. The book begins with a special introductory tutorial for beginners. Following are chapters in Part I addressing fundamental aspects of the approach to automating the creation of finite element solvers. Chapters in Part II address the design and implementation of the FEnicS software. Chapters in Part III present the application of FEniCS to a wide range of applications, including fluid flow, solid mechanics, electromagnetics and geophysics.

Neurotoxicity of Aluminum

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Author :
Publisher : Springer
ISBN 13 : 9811313709
Total Pages : 191 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Neurotoxicity of Aluminum by : Qiao Niu

Download or read book Neurotoxicity of Aluminum written by Qiao Niu and published by Springer. This book was released on 2018-10-12 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.

Computational Fluid and Solid Mechanics 2003

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Publisher : Elsevier
ISBN 13 : 008052947X
Total Pages : 2485 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Computational Fluid and Solid Mechanics 2003 by : K.J Bathe

Download or read book Computational Fluid and Solid Mechanics 2003 written by K.J Bathe and published by Elsevier. This book was released on 2003-06-02 with total page 2485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together the world's leading researchers and practitioners of computational mechanics, these new volumes meet and build on the eight key challenges for research and development in computational mechanics.Researchers have recently identified eight critical research tasks facing the field of computational mechanics. These tasks have come about because it appears possible to reach a new level of mathematical modelling and numerical solution that will lead to a much deeper understanding of nature and to great improvements in engineering design.The eight tasks are: - The automatic solution of mathematical models - Effective numerical schemes for fluid flows - The development of an effective mesh-free numerical solution method - The development of numerical procedures for multiphysics problems - The development of numerical procedures for multiscale problems - The modelling of uncertainties - The analysis of complete life cycles of systems - Education - teaching sound engineering and scientific judgement Readers of Computational Fluid and Solid Mechanics 2003 will be able to apply the combined experience of many of the world's leading researchers to their own research needs. Those in academic environments will gain a better insight into the needs and constraints of the industries they are involved with; those in industry will gain a competitive advantage by gaining insight into the cutting edge research being carried out by colleagues in academia. Features - Bridges the gap between academic researchers and practitioners in industry - Outlines the eight main challenges facing Research and Design in Computational mechanics and offers new insights into the shifting the research agenda - Provides a vision of how strong, basic and exciting education at university can be harmonized with life-long learning to obtain maximum value from the new powerful tools of analysis

Classical And Quantum Dynamics In Condensed Phase Simulations: Proceedings Of The International School Of Physics

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Author :
Publisher : World Scientific
ISBN 13 : 9814496057
Total Pages : 881 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Classical And Quantum Dynamics In Condensed Phase Simulations: Proceedings Of The International School Of Physics by : Bruce J Berne

Download or read book Classical And Quantum Dynamics In Condensed Phase Simulations: Proceedings Of The International School Of Physics written by Bruce J Berne and published by World Scientific. This book was released on 1998-06-17 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: The school held at Villa Marigola, Lerici, Italy, in July 1997 was very much an educational experiment aimed not just at teaching a new generation of students the latest developments in computer simulation methods and theory, but also at bringing together researchers from the condensed matter computer simulation community, the biophysical chemistry community and the quantum dynamics community to confront the shared problem: the development of methods to treat the dynamics of quantum condensed phase systems.This volume collects the lectures delivered there. Due to the focus of the school, the contributions divide along natural lines into two broad groups: (1) the most sophisticated forms of the art of computer simulation, including biased phase space sampling schemes, methods which address the multiplicity of time scales in condensed phase problems, and static equilibrium methods for treating quantum systems; (2) the contributions on quantum dynamics, including methods for mixing quantum and classical dynamics in condensed phase simulations and methods capable of treating all degrees of freedom quantum-mechanically.

Corrosion Engineering : Principles and Practice

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Publisher : McGraw Hill Professional
ISBN 13 : 0071482431
Total Pages : 770 pages
Book Rating : 4.0/5 (714 download)

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Book Synopsis Corrosion Engineering : Principles and Practice by : Pierre Roberge

Download or read book Corrosion Engineering : Principles and Practice written by Pierre Roberge and published by McGraw Hill Professional. This book was released on 2008-03-25 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Latest Methods for Preventing and Controlling Corrosion in All Types of Materials and Applications Now you can turn to Corrosion Engineering for expert coverage of the theory and current practices you need to understand water, atmospheric, and high-temperature corrosion processes. This comprehensive resource explains step-by-step how to prevent and control corrosion in all types of metallic materials and applications-from steel and aluminum structures to pipelines. Filled with 300 illustrations, this skills-building guide shows you how to utilize advanced inspection and monitoring methods for corrosion problems in infrastructure, process and food industries, manufacturing, and military industries. Authoritative and complete, Corrosion Engineering features: Expert guidance on corrosion prevention and control techniques Hands-on methods for inspection and monitoring of corrosion problems New methods for dealing with corrosion A review of current practice, with numerous examples and calculations Inside This Cutting-Edge Guide to Corrosion Prevention and Control • Introduction: Scope and Language of Corrosion • Electrochemistry of Corrosion • Environments: Atmospheric Corrosion • Corrosion by Water and Steam • Corrosion in Soils • Reinforced Concrete • High-Temperature Corrosion • Materials and How They Corrode: Engineering Materials • Forms of Corrosion • Methods of Control: Protective Coatings • Cathodic Protection • Corrosion Inhibitors • Failure Analysis and Design Considerations • Testing and Monitoring: Corrosion Testing and Monitoring

Mems for Biomedical Applications

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Publisher : Elsevier
ISBN 13 : 0857096273
Total Pages : 511 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Mems for Biomedical Applications by : Shekhar Bhansali

Download or read book Mems for Biomedical Applications written by Shekhar Bhansali and published by Elsevier. This book was released on 2012-07-18 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of Micro Electro Mechanical Systems (MEMS) in the biomedical field is leading to a new generation of medical devices. MEMS for biomedical applications reviews the wealth of recent research on fabrication technologies and applications of this exciting technology.The book is divided into four parts: Part one introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms. Part two describes applications of MEMS for biomedical sensing and diagnostic applications. MEMS for in vivo sensing and electrical impedance spectroscopy are investigated, along with ultrasonic transducers, and lab-on-chip devices. MEMS for tissue engineering and clinical applications are the focus of part three, which considers cell culture and tissue scaffolding devices, BioMEMS for drug delivery and minimally invasive medical procedures. Finally, part four reviews emerging biomedical applications of MEMS, from implantable neuroprobes and ocular implants to cellular microinjection and hybrid MEMS.With its distinguished editors and international team of expert contributors, MEMS for biomedical applications provides an authoritative review for scientists and manufacturers involved in the design and development of medical devices as well as clinicians using this important technology. - Reviews the wealth of recent research on fabrication technologies and applications of Micro Electro Mechanical Systems (MEMS) in the biomedical field - Introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms - Considers MEMS for biomedical sensing and diagnostic applications, along with MEMS for in vivo sensing and electrical impedance spectroscopy

Materials that Change Color

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Publisher : Springer Science & Business Media
ISBN 13 : 3319002902
Total Pages : 145 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Materials that Change Color by : Marinella Ferrara

Download or read book Materials that Change Color written by Marinella Ferrara and published by Springer Science & Business Media. This book was released on 2013-11-18 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a design-driven investigation into smart materials developed by chemists, physicists, materials and chemical engineers, and applied by designers to consumer products. Introducing a class of smart materials, that change colors, the book presents their characteristics, advantages, potentialities and difficulties of applications of this to help understanding what they are, how they work, how they are applied. The books also present a number of case studies: products, projects, concepts and experiments using smart materials, thus mapping out new design territories for these innovative materials. These case studies involve different fields of design, including product, interior, fashion and communication design. Within the context of rising sustainable and human-centered design agendas, the series will demonstrate the role and influence of these new materials and technologies on design, and discuss how they can implement and redefine our objects and spaces to encourage more resilient environments.

Managing Space Radiation Risk in the New Era of Space Exploration

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Author :
Publisher : National Academies Press
ISBN 13 : 0309113830
Total Pages : 132 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Managing Space Radiation Risk in the New Era of Space Exploration by : National Research Council

Download or read book Managing Space Radiation Risk in the New Era of Space Exploration written by National Research Council and published by National Academies Press. This book was released on 2008-06-29 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: As part of the Vision for Space Exploration (VSE), NASA is planning for humans to revisit the Moon and someday go to Mars. An important consideration in this effort is protection against the exposure to space radiation. That radiation might result in severe long-term health consequences for astronauts on such missions if they are not adequately shielded. To help with these concerns, NASA asked the NRC to further the understanding of the risks of space radiation, to evaluate radiation shielding requirements, and recommend a strategic plan for developing appropriate mitigation capabilities. This book presents an assessment of current knowledge of the radiation environment; an examination of the effects of radiation on biological systems and mission equipment; an analysis of current plans for radiation protection; and a strategy for mitigating the risks to VSE astronauts.

To Err Is Human

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Publisher : National Academies Press
ISBN 13 : 0309068371
Total Pages : 312 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis To Err Is Human by : Institute of Medicine

Download or read book To Err Is Human written by Institute of Medicine and published by National Academies Press. This book was released on 2000-03-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts estimate that as many as 98,000 people die in any given year from medical errors that occur in hospitals. That's more than die from motor vehicle accidents, breast cancer, or AIDSâ€"three causes that receive far more public attention. Indeed, more people die annually from medication errors than from workplace injuries. Add the financial cost to the human tragedy, and medical error easily rises to the top ranks of urgent, widespread public problems. To Err Is Human breaks the silence that has surrounded medical errors and their consequenceâ€"but not by pointing fingers at caring health care professionals who make honest mistakes. After all, to err is human. Instead, this book sets forth a national agendaâ€"with state and local implicationsâ€"for reducing medical errors and improving patient safety through the design of a safer health system. This volume reveals the often startling statistics of medical error and the disparity between the incidence of error and public perception of it, given many patients' expectations that the medical profession always performs perfectly. A careful examination is made of how the surrounding forces of legislation, regulation, and market activity influence the quality of care provided by health care organizations and then looks at their handling of medical mistakes. Using a detailed case study, the book reviews the current understanding of why these mistakes happen. A key theme is that legitimate liability concerns discourage reporting of errorsâ€"which begs the question, "How can we learn from our mistakes?" Balancing regulatory versus market-based initiatives and public versus private efforts, the Institute of Medicine presents wide-ranging recommendations for improving patient safety, in the areas of leadership, improved data collection and analysis, and development of effective systems at the level of direct patient care. To Err Is Human asserts that the problem is not bad people in health careâ€"it is that good people are working in bad systems that need to be made safer. Comprehensive and straightforward, this book offers a clear prescription for raising the level of patient safety in American health care. It also explains how patients themselves can influence the quality of care that they receive once they check into the hospital. This book will be vitally important to federal, state, and local health policy makers and regulators, health professional licensing officials, hospital administrators, medical educators and students, health caregivers, health journalists, patient advocatesâ€"as well as patients themselves. First in a series of publications from the Quality of Health Care in America, a project initiated by the Institute of Medicine

Occupational Safety and Health Guidance Manual for Hazardous Waste Site Activities

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Author :
Publisher :
ISBN 13 : 9780849050244
Total Pages : pages
Book Rating : 4.0/5 (52 download)

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Book Synopsis Occupational Safety and Health Guidance Manual for Hazardous Waste Site Activities by :

Download or read book Occupational Safety and Health Guidance Manual for Hazardous Waste Site Activities written by and published by . This book was released on 1991-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nondestructive Characterization of Materials IV

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306440472
Total Pages : 536 pages
Book Rating : 4.4/5 (44 download)

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Book Synopsis Nondestructive Characterization of Materials IV by : J.F. Bussière

Download or read book Nondestructive Characterization of Materials IV written by J.F. Bussière and published by Springer Science & Business Media. This book was released on 1992-02-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a great deal of interest in extending nondestructive technologies beyond the location and identification of cracks and voids. Specifically there is growing interest in the application of nondestructive evaluation (NOEl to the measurement of physical and mechanical properties of materials. The measurement of materials properties is often referred to as materials characterization; thus nondestructive techniques applied to characterization become nondestructive characterization (NDCl. There are a number of meetings, proceedings and journals focused upon nondestructive technologies and the detection and identification of cracks and voids. However, the series of symposia, of which these proceedings represent the fourth, are the only meetings uniquely focused upon nondestructive characterization. Moreover, these symposia are especially concerned with stimulating communication between the materials, mechanical and manufacturing engineer and the NDE technology oriented engineer and scientist. These symposia recognize that it is the welding of these areas of expertise that is necessary for practical development and application of NDC technology to measurements of components for in service life time and sensor technology for intelligent processing of materials. These proceedings are from the fourth international symposia and are edited by c.o. Ruud, J. F. Bussiere and R.E. Green, Jr. . The dates, places, etc of the symposia held to date area as follows: Symposia on Nondestructive Methods for TITLE: Material Property Determination DATES: April 6-8, 1983 PLACE: Hershey, PA, USA CHAIRPERSONS: C.O. Ruud and R.E. Green, Jr.

Handbook of Residual Stress and Deformation of Steel

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Author :
Publisher : ASM International
ISBN 13 : 1615032274
Total Pages : 496 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Handbook of Residual Stress and Deformation of Steel by : George E. Totten

Download or read book Handbook of Residual Stress and Deformation of Steel written by George E. Totten and published by ASM International. This book was released on 2002 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Examines the factors that contribute to overall steel deformation problems. The 27 articles address the effect of materials and processing, the measurement and prediction of residual stress and distortion, and residual stress formation in the shaping of materials, during hardening processes, and during manufacturing processes. Some of the topics are the stability and relaxation behavior of macro and micro residual stresses, stress determination in coatings, the effects of process equipment design, the application of metallo- thermo-mechanic to quenching, inducing compressive stresses through controlled shot peening, and the origin and assessment of residual stresses during welding and brazing. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Modelling Aqueous Corrosion

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Publisher : Springer Science & Business Media
ISBN 13 : 9401111766
Total Pages : 467 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Modelling Aqueous Corrosion by : Kenneth R. Threthewey

Download or read book Modelling Aqueous Corrosion written by Kenneth R. Threthewey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: All significant studies agree that aqueous corrosion continues to cost nations dearly in almost every area of technological endeavour. Over the past ten years, microcomputers have facilitated an explosion in the power of modelling as a technique in science and engineering. In corrosion they have enabled better understanding of polarization curves, they have transformed the scope of electrochemical impedance measurements and they have placed a large range of electrochemistry at the fingertips of the corrosion scientist. This book focuses on the models, rather than the computing, which have been made possible during the past decade. Aimed at all those with an interest in corrosion and its control, the book draws together the range of new modelling strands, suggests new avenues of approach and generates further momentum for improvements to corrosion management, whether by increased understanding of atomistic processes or by control of large plant.