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Idiotypy In Biology And Medicine
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Book Synopsis Idiotypy in Biology and Medicine by : Heinz Köhler
Download or read book Idiotypy in Biology and Medicine written by Heinz Köhler and published by Academic Press. This book was released on 2013-10-22 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Idiotypy in Biology and Medicine aims to serve the increasing interest and involvement in the practical aspects of idiotypy in biological systems. The concept of idiotypy has received wide recognition and interest far beyond the area of immunology. Experiments and interpretation of findings, reported here, clearly support the general nature of the idiotype concept in manipulating biological systems to correct pathological conditions or to improve the immune adaptation to environmental factors. The book is organized into three sections. Section 1 discusses original concepts of idiotypic manipulations. It reviews old and recent data important for the concept of an idiotype network and reports on attempts to deal with the T-cell receptor paradox; explains the immune system in terms of a circular idiotype network that can be demonstrated by sequential immunization; and emphasizes the need for restrictions in network interactions. Section 2 addresses the role and activity of idiotypic and antiidiotypic antibodies in the regulation of the immune system. Section 3 takes the issue of idiotype-antiidiotype out of the realm of the immune system and discusses it as a new principle to analyze and manipulate biological systems in general.
Book Synopsis The Biology of Idiotypes by : Mark Greene
Download or read book The Biology of Idiotypes written by Mark Greene and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomenon of idiotypy was discovered almost thirty years ago, but it was only during the past decade that it attracted widespread interest and became the subject of numerous research investigations. From the outset, much of the interest in idiotypy was based on its implications with respect to the repertoire of antibodies. Kunkel showed, for example, that idiotypes associated with certain human myeloma or Bence-Jones proteins were present in normal human globulins at levels of less than one part per million. Also, Oudin's original definition of idiotypy implied that idiotypes could be uniquely associated with individual rabbits as well as with particular antigen-binding specificities. Such observations provided some of the earliest evidence for an extensive repertoire of immunoglobulin molecules. The implications of these findings have been amply confirmed by recent studies of protein struc ture and molecular genetics; many of these studies are reviewed in the present volume. It is known now that the diversity of antibodies is based on the presence of numerous V and L V H genes, on recombinatorial events involving D and] segments, on somatic mutations, and on processes involving deletion of DNA followed by repair with errors, including inser tions. Each of these parameters is capable of influencing the idiotype expressed by the final immunoglobulin product. Regulation of the immune response is another area in which idiotypy has significantly influenced modern immunology.
Book Synopsis Idiotypes in Biology and Medicine by :
Download or read book Idiotypes in Biology and Medicine written by and published by . This book was released on 1990 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Idiotypes in Biology and Medicine by : D.A. Carson
Download or read book Idiotypes in Biology and Medicine written by D.A. Carson and published by . This book was released on 1989 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Idiotype Networks in Biology and Medicine by : Albert Osterhaus
Download or read book Idiotype Networks in Biology and Medicine written by Albert Osterhaus and published by . This book was released on 1990 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Idiotype Networks in Biology and Medicine by : Albert Osterhaus
Download or read book Idiotype Networks in Biology and Medicine written by Albert Osterhaus and published by . This book was released on 1990 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunoglobulin Idiotypes by : Charles Janeway
Download or read book Immunoglobulin Idiotypes written by Charles Janeway and published by . This book was released on 1981 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Biology and its Application to Medical Mycology by : Bruno Maresca
Download or read book Molecular Biology and its Application to Medical Mycology written by Bruno Maresca and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the NATO Advanced Research Workshop on Molecular Biology and its Application to Medical Mycology, held at Taormina, Italy, January 6-8, 1992
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1990 with total page 1128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biological Application of Anti-Idiotypes by : Constantin A. Bona
Download or read book Biological Application of Anti-Idiotypes written by Constantin A. Bona and published by CRC Press. This book was released on 2018-01-18 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to present findings which are supportive of the concept that the words of the idiotype dictionary and likewise self-recognition are essential for communication between lymphocyte clones while some unfaithful (infidel) copies of the words contained in the idiotype dictionary perhaps play a role in the functional regulation of nonlymphoid cells.
Book Synopsis Current Catalog by : National Library of Medicine (U.S.)
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1120 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis Idiotypes in Medicine: Autoimmunity, Infection and Cancer by : R.C. Kennedy
Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Book Synopsis Immunobiology of Proteins and Peptides V by : M. Atassi
Download or read book Immunobiology of Proteins and Peptides V written by M. Atassi and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Fifth International Symposium held in Alberta, Canada, Oct. 1988. Articles are focused on the field of vaccines against viral, bacterial, and parasitic agents. Topics include: cytotoxic and helper T-lymphocyte responses to antibody, the application of molecular biology to the deve
Author :Pierre-Andre Cazenave Publisher :Springer Science & Business Media ISBN 13 :1461229928 Total Pages :152 pages Book Rating :4.4/5 (612 download)
Book Synopsis Anti-Idiotypic Vaccines by : Pierre-Andre Cazenave
Download or read book Anti-Idiotypic Vaccines written by Pierre-Andre Cazenave and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vaccines have historically been considered to be the most cost-effective method for preventing communicable diseases. It was a vaccine~hat enabled global eradication of the dreaded disease smallpox. Mass immunization of children forms the anchor of the strategy of the World Health Organization (WHO) to attain "health for all" status by the year 2000. Vaccinology is undergoing a dimensional change with the advances that have taken place in immunology and genetic engineering. Vaccines that confer short or inadequate immunity or that have side effects are being replaced by better vaccines. New vaccines are being developed for a variety of maladies. Monoclonal antibodies and T cell clones have been employed to delineate the immunodeterminants on microbes, an approach elegantly complemented by computer graphics and molecular imaging techniques. Possibilities have opened for obtaining hitherto scarce antigens of parasites by the DNA recombinant route. Better appreciation of the idiotypic network has aroused research on anti-idiotypic vaccines. Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out. A new breed of vaccines is on the horizon that seeks to control fertility.
Book Synopsis The United States-Japan Cooperative Medical Science Program by :
Download or read book The United States-Japan Cooperative Medical Science Program written by and published by . This book was released on 1990 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Published Scientific Papers of the National Institutes of Health by : National Institutes of Health (U.S.)
Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.) and published by . This book was released on 1990 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the broad outline of NIH organizational structure, theprofessional staff, and their scientific and technical publications covering work done at NIH.
Book Synopsis Five Year Report by : United States-Japan Cooperative Medical Science Program
Download or read book Five Year Report written by United States-Japan Cooperative Medical Science Program and published by . This book was released on 1990 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
