Genetics of Colorectal Cancer

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Author :
Publisher : Springer
ISBN 13 : 9780387095677
Total Pages : 309 pages
Book Rating : 4.0/5 (956 download)

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Book Synopsis Genetics of Colorectal Cancer by : John D. Potter

Download or read book Genetics of Colorectal Cancer written by John D. Potter and published by Springer. This book was released on 2008-12-08 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.

Colorectal Cancer Liver Metastases

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Author :
Publisher : Springer Nature
ISBN 13 : 3030254860
Total Pages : 597 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia

Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer Nature. This book was released on 2019-12-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

The Surfaceome

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Author :
Publisher : Humana Press
ISBN 13 : 9781493975518
Total Pages : 348 pages
Book Rating : 4.9/5 (755 download)

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Book Synopsis The Surfaceome by : Kenneth R. Boheler

Download or read book The Surfaceome written by Kenneth R. Boheler and published by Humana Press. This book was released on 2017-12-20 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with the latest techniques and tools to assess modifications and functions of the surfaceome. The chapters in this book are divided into 4 sections: discovery-based approaches to surfaceome content; targeted approaches for surfaceome content; cell-based function analyses related to surfaceome content; and computational approaches in surfaceome studies. Section 1 focuses on discovery-based approaches for cataloging surfaceome content that analyses the surfaceome of bacteria, avian embryos, and mammalian systems. Section 2 discusses methods that over-express specific targets in Sf9 cells and generate bi-specific antibodies for targeting cancer and somatic cells. Section 3 explores voltage dependent sodium channels and high-content electrophysiological analyses. The final section looks at the new web-based platform known as targets-search. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and thorough, Surfaceome: Methods and Protocols assists in the study of cell surface protein biology and function. It is a valuable resource for all researchers interested in this field.

Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481651668
Total Pages : 1157 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition by :

Download or read book Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 1157 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Colon Cancer: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Identification of Novel Biomarkers for Pancreatic and Hepatocellular Cancers

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832508367
Total Pages : 240 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identification of Novel Biomarkers for Pancreatic and Hepatocellular Cancers by : Brendan Jenkins

Download or read book Identification of Novel Biomarkers for Pancreatic and Hepatocellular Cancers written by Brendan Jenkins and published by Frontiers Media SA. This book was released on 2022-12-02 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colorectal Cancer Screening

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1607613980
Total Pages : 210 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Colorectal Cancer Screening by : Joseph Anderson, MD

Download or read book Colorectal Cancer Screening written by Joseph Anderson, MD and published by Springer Science & Business Media. This book was released on 2011-04-23 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.

Molecular Pathogenesis of Colorectal Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 146148412X
Total Pages : 319 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Molecular Pathogenesis of Colorectal Cancer by : Kevin M. Haigis, Ph.D.

Download or read book Molecular Pathogenesis of Colorectal Cancer written by Kevin M. Haigis, Ph.D. and published by Springer Science & Business Media. This book was released on 2013-10-02 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

Role of Biomarkers in Medicine

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535125052
Total Pages : 262 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Role of Biomarkers in Medicine by : Mu Wang

Download or read book Role of Biomarkers in Medicine written by Mu Wang and published by BoD – Books on Demand. This book was released on 2016-08-17 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.

Prevention and Early Detection of Colorectal Cancer

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Author :
Publisher : W.B. Saunders Company
ISBN 13 :
Total Pages : 410 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Prevention and Early Detection of Colorectal Cancer by : Graeme P. Young

Download or read book Prevention and Early Detection of Colorectal Cancer written by Graeme P. Young and published by W.B. Saunders Company. This book was released on 1996 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.

Bioinformatics and Computational Biology Solutions Using R and Bioconductor

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387293620
Total Pages : 478 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Bioinformatics and Computational Biology Solutions Using R and Bioconductor by : Robert Gentleman

Download or read book Bioinformatics and Computational Biology Solutions Using R and Bioconductor written by Robert Gentleman and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

Emerging therapeutic targets, potential diagnostic or prognostic markers for colorectal cancer

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832526195
Total Pages : 359 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Emerging therapeutic targets, potential diagnostic or prognostic markers for colorectal cancer by : Muzafar Ahmad Macha

Download or read book Emerging therapeutic targets, potential diagnostic or prognostic markers for colorectal cancer written by Muzafar Ahmad Macha and published by Frontiers Media SA. This book was released on 2023-06-09 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structural and Functional Characterization of Circular RNAs

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Publisher : Frontiers Media SA
ISBN 13 : 2889719286
Total Pages : 197 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Structural and Functional Characterization of Circular RNAs by : Amaresh Chandra Panda

Download or read book Structural and Functional Characterization of Circular RNAs written by Amaresh Chandra Panda and published by Frontiers Media SA. This book was released on 2022-01-04 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomarkers in Cancer Screening and Early Detection

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118468805
Total Pages : 334 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Biomarkers in Cancer Screening and Early Detection by : Sudhir Srivastava

Download or read book Biomarkers in Cancer Screening and Early Detection written by Sudhir Srivastava and published by John Wiley & Sons. This book was released on 2017-08-28 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to help develop personalized cancer treatment for individual patients with specific cancers

Electrochemical Biosensors

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Publisher : CRC Press
ISBN 13 : 9814411477
Total Pages : 405 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Electrochemical Biosensors by : Serge Cosnier

Download or read book Electrochemical Biosensors written by Serge Cosnier and published by CRC Press. This book was released on 2015-01-26 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since four decades, rapid detection and monitoring in clinical and food diagnostics and in environmental and biodefense have paved the way for the elaboration of electrochemical biosensors. Thanks to their adaptability, ease of use in relatively complex samples, and their portability, electrochemical biosensors now are one of the mainstays of analy

The Genetic Basis of Human Cancer

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Publisher : McGraw Hill Professional
ISBN 13 : 9780071370509
Total Pages : 358 pages
Book Rating : 4.3/5 (75 download)

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Book Synopsis The Genetic Basis of Human Cancer by : Kenneth W. Kinzler

Download or read book The Genetic Basis of Human Cancer written by Kenneth W. Kinzler and published by McGraw Hill Professional. This book was released on 2002 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: -- Current coverage of diagnosis and treatment on a wide spectrum of active cancer research.

Nanobiosensors

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Publisher : John Wiley & Sons
ISBN 13 : 3527345108
Total Pages : 412 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Nanobiosensors by : Aiguo Wu

Download or read book Nanobiosensors written by Aiguo Wu and published by John Wiley & Sons. This book was released on 2020-06-02 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing cutting edge research on the hot topic of nanobiosensor, this book will become highly read Biosensor research has recently re-emerged as most vibrant area in recent years particularly after the advent of novel nanomaterials of multidimensional features and compositions. Nanomaterials of different types and striking properties have played a positive role in giving the boost and accelerated pace to biosensors development technology. Nanobiosensors - From Design to Applications covers several aspects of biosensors beginning from the basic concepts to advanced level research. It will help to bridge the gap between various aspects of biosensors development technology and applications. It covers biosensors related material in broad spectrum such as basic concepts, biosensors & their classification, biomarkers & their role in biosensors, nanostructures-based biosensors, applications of biosensors in human diseases, drug detection, toxins, and smart phone based biosensors. Nanobiosensors - From Design to Applications will prove a source of inspiration for research on biosensors, their local level development and consequently using for practical application in different industries such as food, biomedical diagnosis, pharmaceutics, agriculture, drug discovery, forensics, etc. * Discusses the latest technology and advances in the field of nanobiosensors and their applications in human diseases, drug detection, toxins * Offers a broad and comprehensive view of cutting-edge research on advanced materials such as carbon materials, nitride based nanomaterials, metal and metal oxide based nanomaterials for the fast-developing nanobiosensors research * Goes to a wide scientific and industry audience Nanobiosensors - From Design to Applications is a resource for polymer chemists, spectroscopists, materials scientists, physical chemists, surface chemists, and surface physicists.

Epigenetic Biomarkers and Diagnostics

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Author :
Publisher : Academic Press
ISBN 13 : 0128019212
Total Pages : 698 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetic Biomarkers and Diagnostics by : Jose Luis Garcia-Gimenez

Download or read book Epigenetic Biomarkers and Diagnostics written by Jose Luis Garcia-Gimenez and published by Academic Press. This book was released on 2015-12-07 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. - Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics - Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics - Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications - Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases - Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies