Hormones, Neurotransmitters, and T-Cell Development in Health and Disease

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Publisher : Frontiers Media SA
ISBN 13 : 2889630269
Total Pages : 110 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Hormones, Neurotransmitters, and T-Cell Development in Health and Disease by : Wilson Savino

Download or read book Hormones, Neurotransmitters, and T-Cell Development in Health and Disease written by Wilson Savino and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thymus physiology and T-cell homeostasis are controlled by hormones, neurotransmitters, cytokines and other factors that modulate stromal-cell interactions, influence thymocyte development and selection processes, survival and migration, between others. In the context of this Research Topic on “Hormones, Neurotransmitters, and T cell development in Health and Disease”, authors discuss the control of thymus physiology by glucocorticoids (GC), growth hormone (GH) and sex hormones, norepinephrine (NE) and other molecules that seem impact upon thymocyte/microenvironmental interactions, like galectin-3 (Gal-3) ephrins (Eph), extracellular matrix proteins and integrins (like VLA-5). Moreover, some of them draw attention to about how diverse maturation steps and/or the interactions between stromal and thymocytes can be affected in pathological states like diabetes or infections. As shown schematically in the figure, this topic highlight the following notions: 1) GH shows counterregulatory effects against GC rather than influence directly T cell homeostasis; 2) Interactions between sex hormones and noradrenergic secretion may influence thymus homeostasis and involution; 3) Gal-3 are crucial to thymocyte-stromal cell interactions and influence thymic architecture. Moreover, Gal-3 seem to be involved in the regulation of steroidogenic pathway; 4) Ephrins are crucial to assembly the thymic connections between thymocytes and the epithelial network, but have a relative importance in supporting normal thymopoyesis; 5) Pathologic situations like diabetes, or infectious diseases caused by parasites or bacteria alters the normal development of T-lymphocytes and might influence tolerance process. DN: double-negative (CD4-CD8) thymocytes; DP: double-positive (CD4+CD8+) thymocytes; SP: simple-positive thymocytes; LT: T lymphocyte; FN: fibronectin; PVS: peri-vascular space; BM: bone marrow; DBT: diabetes; Eph: Ephrins.

Novel Aspects of Neurotransmitters

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Publisher : Frontiers Media SA
ISBN 13 : 2889740102
Total Pages : 117 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Novel Aspects of Neurotransmitters by : Zhi-Gang Zhang

Download or read book Novel Aspects of Neurotransmitters written by Zhi-Gang Zhang and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Introduction to Neuroendocrinology

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Publisher : Cambridge University Press
ISBN 13 : 9780521426657
Total Pages : 434 pages
Book Rating : 4.4/5 (266 download)

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Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown

Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

The Neuron

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Publisher : Oxford University Press, USA
ISBN 13 : 9780195145236
Total Pages : 640 pages
Book Rating : 4.1/5 (452 download)

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Book Synopsis The Neuron by : Irwin B. Levitan

Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2002 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Nerve-Driven Immunity

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Publisher : Springer Science & Business Media
ISBN 13 : 3709108888
Total Pages : 374 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Nerve-Driven Immunity by : Mia Levite

Download or read book Nerve-Driven Immunity written by Mia Levite and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” summarizes, analyzes and sheds new light on an unrecognized, yet very important role of key neurotransmitters and neuropeptides in the immune system. Each chapter of the book deals with a different neurotransmitter/neuropeptide from the following list: Dopamine, Adrenaline, Noradrenaline, Acetylcholine, Glutamate, GABA, Somatostatin, Neuropeptide Y (NPY), Vasoactive intestinal polypeptide (VIP), Calcitonin gene related peptide (CGRP), Opioids and Cannabinoids. For each of these neurotransmitters/neuropeptides, the following four topics are discussed: The specific receptors for the neurotransmitter/neuropeptide expressed in various types of immune cells The direct effects induced by the neurotransmitter/neuropeptide in various types of immune cells (either resting or activated), and the specific immune functions and features it activates/elevates or rather inhibits in specific concentrations The production of the neurotransmitter/neuropeptide in, and its release by, various types of immune cells The involvement of the neurotransmitter/neuropeptide in various diseases of the immune system (among them autoimmune diseases, immunodeficiency diseases and hematological cancers) The book includes many original figures, overview tables, and proposed models of events which are instrumental, enriching and stimulating for the reader. In light of the above-mentioned aspects, “Nerve-Driven Immunity: Neurotransmitters and Neuropeptides in the Immune System” is ideally suited as a textbook for new courses in Immunology, Neurology, Neuro-immunology or Pharmacology. The book chapters were written by highly skilled authors from 10 countries: the USA, the United Kingdom, Italy, Israel, Sweden, France, Germany, Spain, Serbia and Romania. “Nerve-Driven Immunity” is a term first coined by Dr. Mia Levite (the editor of the book).

The Reticuloendothelial System in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 1468433008
Total Pages : 480 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Reticuloendothelial System in Health and Disease by : Herman Friedman

Download or read book The Reticuloendothelial System in Health and Disease written by Herman Friedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroendocrine-immune Interactions

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805572824
Total Pages : 144 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Neuroendocrine-immune Interactions by : Rolf C. Gaillard

Download or read book Neuroendocrine-immune Interactions written by Rolf C. Gaillard and published by Karger Medical and Scientific Publishers. This book was released on 2002 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interactions between the immune, endocrine and nervous systems seldom appear as main issues in the neurosciences and in immunology. So far this was most likely due to the need to focus on the molecular and cellular bases of single neural, endocrine and immune processes. But hormones, neurotransmitters and neuropeptides can also influence more subtle mechanisms underlying immune cell activity. The contents of this volume aim at listing some aspects which show that not only the bases for neuroendocrine control of more refined mechanisms related to the organization and functioning of the immune systems to exist, but also that the immune system can actively communicate with neuroendocrine structures. The evidence is divided into three categories: - Anatomical, cellular and molecular bases for the exchange of information between immune, endocrine and neural cells, - reciprocal effects between immune and neuroendocrine mechanisms, and - immune-neuroendocrine regulatory circuits. Immunologically triggered neuroendocrine responses can be either beneficial or deleterious for the host. A systematic approach would imply the simultaneous evaluation of neuroendocrine and immune parameters and thus provide the basis for therapeutic interventions based on antagonizing or blocking undesirable effects.

Rheumatology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0702063037
Total Pages : 2047 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Rheumatology E-Book by : Marc C. Hochberg

Download or read book Rheumatology E-Book written by Marc C. Hochberg and published by Elsevier Health Sciences. This book was released on 2014-06-16 with total page 2047 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.

Handbook on Immunosenescence

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Publisher : Springer Science & Business Media
ISBN 13 : 1402090633
Total Pages : 1693 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Immunosenescence by : Tamas Fulop

Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.

Inflammation, 4 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 3527338993
Total Pages : 1818 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon

Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference on this topic of increasing medical relevance is unique in offering unparalleled coverage. The editors are among the most respected researchers in inflammation worldwide and here have put together a prestigious team of contributors. Starting with the molecular basis of inflammation, from cytokines via the innate immune system to the different kinds of inflammatory cells, they continue with the function of inflammation in infectious disease before devoting a large section to the relationship between inflammation and chronic diseases. The book concludes with wound and tissue healing and options for therapeutic interventions. A must have for clinicians and biomedical researchers alike.

Indexes

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Publisher :
ISBN 13 :
Total Pages : 132 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Indexes by : National Institute of Dental Research (U.S.)

Download or read book Indexes written by National Institute of Dental Research (U.S.) and published by . This book was released on with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pituitary Adenylate Cyclase-Activating Polypeptide

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402073069
Total Pages : 432 pages
Book Rating : 4.0/5 (73 download)

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Book Synopsis Pituitary Adenylate Cyclase-Activating Polypeptide by : Hubert Vaudry

Download or read book Pituitary Adenylate Cyclase-Activating Polypeptide written by Hubert Vaudry and published by Springer Science & Business Media. This book was released on 2003 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Meet Your Happy Chemicals

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Publisher : Loretta Graziano Breuning
ISBN 13 : 9781941959015
Total Pages : 0 pages
Book Rating : 4.9/5 (59 download)

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Book Synopsis Meet Your Happy Chemicals by : Loretta Graziano Breuning

Download or read book Meet Your Happy Chemicals written by Loretta Graziano Breuning and published by Loretta Graziano Breuning. This book was released on 2012-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "happy chemicals" are controlled by tiny brain structures that all mammals have in common. Your brain rewards you with good feelings when you do something good for your survival. But we struggle to make sense of our neurochemical ups and downs, and can trigger vicious cycles such as alcohol, junk food, risk-taking. Learn how to make real-world choices that will help you break the cycles.

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2292 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Biomedical Index to PHS-supported Research

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Publisher :
ISBN 13 :
Total Pages : 1104 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sex Hormones and Gender Differences in Immune Responses

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Publisher : Frontiers Media SA
ISBN 13 : 2889459365
Total Pages : 186 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Sex Hormones and Gender Differences in Immune Responses by : Elena Ortona

Download or read book Sex Hormones and Gender Differences in Immune Responses written by Elena Ortona and published by Frontiers Media SA. This book was released on 2019-07-31 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasingly clear evidence points to the need to consider gender differences in human health. In this collection of papers, recent research that supports gender differences in the immune system are discussed. We have loosely divided the eBook into two sections. The first section focuses on the role of steroid hormone interactions within the immune system, and their impact on autoimmune diseases, infection and allergy. This section contains comprehensive reviews and an opinion article about this topic. In the following section, original research articles revolve around the effects of the sex hormones on immune response. Two original manuscripts deal with the role of estrogen receptors in autoimmune diseases. Other two research articles discuss the role of the immune system during pregnancy. Finally, differences between males and females in infections are the topic of further two research articles. We are confident this collection of papers will be important for exploring and developing a greater understanding of gender differences in human health and disease.

Research Awards Index

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Publisher :
ISBN 13 :
Total Pages : 742 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: