Hormone Receptors: Structures and Functions

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Publisher : Elsevier
ISBN 13 : 0443134561
Total Pages : 688 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Hormone Receptors: Structures and Functions by :

Download or read book Hormone Receptors: Structures and Functions written by and published by Elsevier. This book was released on 2023-09-01 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone Receptors: Structures and Functions, Volume 123 in the Vitamins and Hormones series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on Hormone Receptors

Steroid Hormone Receptors

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Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Steroid Hormone Receptors by : Håkan Eriksson

Download or read book Steroid Hormone Receptors written by Håkan Eriksson and published by Elsevier Science & Technology. This book was released on 1983 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid Hormone Receptors: Basic and Clinical Aspects

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461598494
Total Pages : 519 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Steroid Hormone Receptors: Basic and Clinical Aspects by : V. K. Moudgil

Download or read book Steroid Hormone Receptors: Basic and Clinical Aspects written by V. K. Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.

Receptors and Hormone Action

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Publisher : Elsevier
ISBN 13 : 0323144942
Total Pages : 597 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Receptors and Hormone Action by : Bert O'Malley

Download or read book Receptors and Hormone Action written by Bert O'Malley and published by Elsevier. This book was released on 2012-12-02 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Receptors and Hormone Action, Volume 1, provides an overview of the state of knowledge in hormone action. This book describes basic methodologies and model systems used in the exploration of the molecular bases of hormone action. The chapters present not only a rather extensive description of hormone receptors and their properties, but also basic aspects of structure and function of chromatin and membranes, the sites at which hormones and their receptors exert their action. The receptors discussed include soluble cytoplasmic and nuclear receptors for steroid hormones and vitamins, membrane-bound receptors for protein hormones and biogenic amines, and nuclear receptors for thyroid hormones. Receptor types are also covered in view of the large body of literature accumulated on the various functions of these fascinating but elusive molecules. This book is intended for a broad spectrum of readers, including those who have not yet worked in the field as well as those who have considerable expertise in one or another aspect of hormone action.

Molecular Biology of Steroid and Nuclear Hormone Receptors

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Publisher : Springer Science & Business Media
ISBN 13 : 1461217644
Total Pages : 330 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Molecular Biology of Steroid and Nuclear Hormone Receptors by : Leonard Freedman

Download or read book Molecular Biology of Steroid and Nuclear Hormone Receptors written by Leonard Freedman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracellular Receptors: New Instruments for a Symphony of Signals In the late eighteenth century, it was proposed on theoretical grounds that each of the body's organs, beginning with the brain, must be "a factory and laboratory of a specific humor which it returns to the blood", and that these circulating signals "are indispensable for the life of the whole" (Bordeu 1775). During the nineteenth cen tury, some remarkable physiological experiments revealed the actions of humoral factors that affected the for and function of multiple tissues, organs and organ sys tems within the body (Berthold 1849); much later, the chemical and molecular na ture of some of those factors was determined. Against this deep historical backdrop of the founding studies of intercellular signaling, molecular biology sprang into existence a mere forty years ago, rooted in the revelation of regulable gene expression in bacteria. But contemporaneous with those classical analyses of transcriptional regulation of the lactose operon, the mod em era of signal transduction was inaugurated by the identification of cAMP as a second messenger -- an intracellular mediator of hormonal activation of glycogen catabolism (Sutherland and RaIl 1960). Later in that same decade, it emerged that cAMP is a critical signal not only in metazoans, but even in bacteria, where it serves an analogous function as a critical switch that activates expression of genes re quired for catabolism of complex carbon sources, including those of the lactose operon.

Steroid Hormone Receptors

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (311 download)

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Book Synopsis Steroid Hormone Receptors by : Håkan Eriksson

Download or read book Steroid Hormone Receptors written by Håkan Eriksson and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nuclear Hormone Receptors

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Publisher :
ISBN 13 :
Total Pages : 434 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Nuclear Hormone Receptors by : Malcolm G. Parker

Download or read book Nuclear Hormone Receptors written by Malcolm G. Parker and published by . This book was released on 1991 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the supergene family made up of those nuclear hormone receptors which recognize thyroid and steroid hormones, vitamen D and retinoic acid and which are characterized by their ability to bind both ligands and the genes which respond to them.

Steroid Hormone Receptors

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Publisher :
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.:/5 (83 download)

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Book Synopsis Steroid Hormone Receptors by : H°akan Eriksson

Download or read book Steroid Hormone Receptors written by H°akan Eriksson and published by . This book was released on 1983 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Anatomy and Physiology

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Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid Hormone Receptors: Structure and Function, Nobel Symposium

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (985 download)

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Book Synopsis Steroid Hormone Receptors: Structure and Function, Nobel Symposium by : H Eriksson (Ed)

Download or read book Steroid Hormone Receptors: Structure and Function, Nobel Symposium written by H Eriksson (Ed) and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Basis of Sex Hormone Receptor Function

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Publisher : Springer Science & Business Media
ISBN 13 : 3662036894
Total Pages : 280 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Molecular Basis of Sex Hormone Receptor Function by : Hinrich Gronemeyer

Download or read book Molecular Basis of Sex Hormone Receptor Function written by Hinrich Gronemeyer and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: How sex hormone receptors and all the other members of the nuclear receptor superfamily do such a remarkable job has fascinated scientists for decades. A series of discoveries in the past few years has dramatically enlightened our understanding of the molecular mechanisms that govern nuclear receptor action. The elucidation of the 3D structures of several nuclear receptor ligand binding domains in the presence of agonists or antagonists has provided an allosteric concept of ligand action, and the discovery of a plethora of ligand-dependent protein interactions has linked this transconformation with the ability of nuclear receptors to act as transcriptional activators and repressors and the enzymatic modification of chromatin and factors of the basal transcriptional machinery.

Steroid Hormone Receptors in Health and Disease

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Publisher : Elsevier
ISBN 13 : 0323998461
Total Pages : 174 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Steroid Hormone Receptors in Health and Disease by : Raj Kumar

Download or read book Steroid Hormone Receptors in Health and Disease written by Raj Kumar and published by Elsevier. This book was released on 2023-12-15 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases. Discusses the importance of steroid hormone receptors in the physiology and pathophysiology of various endocrine related diseases Provides state-of-the-art information based on key research findings in the field, along with hypotheses and perspectives for future directions for basic and translational research and clinical applications Offers a comprehensive description of the challenges associated with steroid hormone receptors-based therapies

Hormone Signaling

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792376606
Total Pages : 340 pages
Book Rating : 4.3/5 (766 download)

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Book Synopsis Hormone Signaling by : Vincent Goffin

Download or read book Hormone Signaling written by Vincent Goffin and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.

Ecdysone: Structures and Functions

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Publisher : Springer Science & Business Media
ISBN 13 : 1402091125
Total Pages : 583 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ecdysone: Structures and Functions by : Guy Smagghe

Download or read book Ecdysone: Structures and Functions written by Guy Smagghe and published by Springer Science & Business Media. This book was released on 2009-03-06 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecdysone is the steroidal prohormone of the major insect moulting hormone 20-hydroxyecdysone. It groups with its homologues the steroidal molting hormones in arthropods, but they also occur in other phyla where they can play different roles. Besides ecdysteroids appear in many plants mostly as protection agents (toxins or antifeedants) against herbivorous insects. The important developments and achievements in modern ecdysone science since the first edition in 1989 by J. Koolman have led to this new revised, expanded and retitled reference work. New chapters in this edition include RNA interference, the ecdysone receptor crystal structures and structure activity relationships, etc. Each article may also be read independently, as a review of that particular subject. Complete up-to-date coverage of many important topics - the book is divisible into five conceptual areas: (1) Distribution and diversity of ecdysteroids in the two kingdoms is still basis, (2) In the post-genomic era, ecdysteroid genetic hierarchies in insect growth and reproduction, (3) Role of cross talk of genes and growth factors in ecdysteroid titers and signaling, (4) Ecdysteroids function through nuclear and membrane receptors, and (5) Ecdysteroids in modern agriculture, medicine, doping and ecotoxicology. Each of the 23 chapters is written by scientists active in the reviewed research area and a truly distinguished international team of contributors has been chosen. Ecdysone, Structures and Functions will be of immense use and contains essential information for scientists, students, and professionals alike in entomology, endocrinology, physiology, chemistry, and agricultural, plant, biomedicine and environmental sciences.

An Introduction to Neuroendocrinology

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Publisher : Cambridge University Press
ISBN 13 : 9780521426657
Total Pages : 434 pages
Book Rating : 4.4/5 (266 download)

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Book Synopsis An Introduction to Neuroendocrinology by : Richard E. Brown

Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.

Hormonally Active Agents in the Environment

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Publisher : National Academies Press
ISBN 13 : 0309064198
Total Pages : 453 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Hormonally Active Agents in the Environment by : National Research Council

Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.

The Structure and Function of Neurohypophysical Hormone Receptors

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Publisher :
ISBN 13 :
Total Pages : 339 pages
Book Rating : 4.:/5 (911 download)

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Book Synopsis The Structure and Function of Neurohypophysical Hormone Receptors by :

Download or read book The Structure and Function of Neurohypophysical Hormone Receptors written by and published by . This book was released on 2007 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: