Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques

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Publisher : Academic Press
ISBN 13 : 0323913989
Total Pages : 294 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques by : George Parker

Download or read book Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques written by George Parker and published by Academic Press. This book was released on 2022-08-03 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histopathology Atlas of Acute Radiation Syndrome and Delayed Effects in Rhesus Macaques: Kidney, Lung, Heart, Intestine and Mesenteric Lymph Node provides a thoroughly illustrated review of the tissue damage and reparative changes associated with standardized irradiation doses in rhesus macaques. In addition to time-sequenced, routinely stained histologic sections, the book presents results of numerous histochemical, immunohistochemical and chromogenic in-situ stains that provide insights into the pathogenesis of radiation-associated tissue injury and repair. This book is compiled and written by a board-certified veterinary pathologist with more than 40 years of experience in the interpretation of experimentally induced tissue alterations in laboratory animals. This is an important resource for researchers in the field of animal science radiation injury, including radiation oncologists and individuals involved in disaster preparedness related to accidental or deliberate radiation exposure in large populations. Addresses the chronological sequence of tissue alterations following defined radiation doses in rhesus macaques Provides photo-documentation of a broad range of histochemical and immunohistochemical stains that illustrate tissue damage and reparative changes following irradiation Presents insights into the involvement of various signaling and effector molecules in the development of radiation-associated injury

Radiation Myelopathy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030946584
Total Pages : 240 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Radiation Myelopathy by : Timothy Schultheiss

Download or read book Radiation Myelopathy written by Timothy Schultheiss and published by Springer Nature. This book was released on 2022-08-01 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers every aspect of radiation myelopathy and considers the evidence from all species in which it has been studied. The historical and current understanding of the pathogenesis of this rare but devastating injury is first discussed. The evidence regarding the role of a variety of factors in radiation myelopathy is then reviewed. Readers will find detailed information on the impacts of total radiation dose, radiation volume, dose fractionation, hyper fractionation, age, anatomic level, comorbidities, radiation modifiers, other therapies, and retreatment of the spinal cord. Given the similarity of the pathogenesis of radiation myelopathy in humans and experimental animals, the potential for cross-species modelling of dose response is explored, with attention to relevant species differences. Treatment of the condition is also fully considered. New theories are presented regarding retreatment, small volume response, and the final step in white matter necrosis. The final chapter addresses the medicolegal issues elicited by radiation myelopathy, which is often the result of treatment error. Radiation Myelopathy will be of high value for radiation oncologists, radiation physicists, dosimetrists, biologists, neurologists, medical oncologists, and attorneys.

Anthrax in Humans and Animals

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547537
Total Pages : 219 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Anthrax in Humans and Animals by : World Health Organization

Download or read book Anthrax in Humans and Animals written by World Health Organization and published by World Health Organization. This book was released on 2008 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the anthrax guidelines encompasses a systematic review of the extensive new scientific literature and relevant publications up to end 2007 including all the new information that emerged in the 3-4 years after the anthrax letter events. This updated edition provides information on the disease and its importance, its etiology and ecology, and offers guidance on the detection, diagnostic, epidemiology, disinfection and decontamination, treatment and prophylaxis procedures, as well as control and surveillance processes for anthrax in humans and animals. With two rounds of a rigorous peer-review process, it is a relevant source of information for the management of anthrax in humans and animals.

Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research

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Publisher : National Academies Press
ISBN 13 : 0309488516
Total Pages : 123 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research by : National Academies of Sciences, Engineering, and Medicine

Download or read book Care, Use, and Welfare of Marmosets as Animal Models for Gene Editing-Based Biomedical Research written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-08-26 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Atlas of Human Brain Connections

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Publisher : Oxford University Press, USA
ISBN 13 : 0199541167
Total Pages : 533 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Atlas of Human Brain Connections by : Marco Catani

Download or read book Atlas of Human Brain Connections written by Marco Catani and published by Oxford University Press, USA. This book was released on 2012-06-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour. This atlas capitalises on novel diffusion MRI tractography methods to provide a comprehensive overview of connections derived from virtual in vivo tractography dissections of the human brain.

Clues in the Diagnosis of Non-tumoral Testicular Pathology

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Author :
Publisher : Springer
ISBN 13 : 3319493647
Total Pages : 378 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Clues in the Diagnosis of Non-tumoral Testicular Pathology by : Manuel Nistal

Download or read book Clues in the Diagnosis of Non-tumoral Testicular Pathology written by Manuel Nistal and published by Springer. This book was released on 2017-03-07 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the morphology of different non-tumoral lesions of the testis. By showing the differential diagnosis of each lesion, it offers clinicians vital support with diagnosis and treatment. The book is divided into seven main parts: genetic and developmental pathology of the testis; infertility; vascular pathology of the testis; inflammatory pathology; pathology of the rete testis and epididymis; pathology of the vaginal tunic and paratesticular structures; and a final part dealing with miscellanea. Each chapter includes carefully selected figures and a variety of diagrams highlighting the main characteristics of a specific lesion to facilitate its diagnosis.Based on the authors’ experience with hundreds of biopsies, surgical specimens and autopsies, the book presents material that has been gathered over the past 40 years, providing an essential tool for pathologists, urologists, andrologists and pediatricians who face diagnostic problems.

Stroke Syndromes, 3ed

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Publisher : Cambridge University Press
ISBN 13 : 1107018862
Total Pages : 633 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Stroke Syndromes, 3ed by : Louis R. Caplan

Download or read book Stroke Syndromes, 3ed written by Louis R. Caplan and published by Cambridge University Press. This book was released on 2012-07-12 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of dysfunction due to stroke, this revised edition remains the definitive guide to stroke patterns and syndromes.

Pulmonary Pathology E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 143772048X
Total Pages : 853 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Pulmonary Pathology E-Book by : Dani S. Zander

Download or read book Pulmonary Pathology E-Book written by Dani S. Zander and published by Elsevier Health Sciences. This book was released on 2008-07-02 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Foundations in Diagnostic Pathology Series packs today's most essential pulmonary pathology into a compact, high-yield format! It covers both common and rare neoplastic and non-neoplastic diseases of the lung and pleura and focuses primarily on diagnosis with correlations to clinical and radiographic characteristics. Its pragmatic, well-organized approach, abundant full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Detailed discussions on today’s technologies help you select the best test for case evaluation. Chapters devoted to the techniques used in the assessment of pulmonary diseases, including immunohistochemistry, immunofluorescnece, and certain clinical laboratory tests offer you a better understanding of techniques and their application for the diagnosis of lung disease. Internationally recognized pathologists convey the most current information, keeping you on the cusp of your field. More than 800 photomicrographs and gross photographs—most in full color—present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Oxford Textbook of Endocrinology and Diabetes

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Publisher : Oxford University Press, USA
ISBN 13 : 0199235295
Total Pages : 2158 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Oxford Textbook of Endocrinology and Diabetes by : John A.H. Wass

Download or read book Oxford Textbook of Endocrinology and Diabetes written by John A.H. Wass and published by Oxford University Press, USA. This book was released on 2011-07-28 with total page 2158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, the Oxford Textbook of Endocrinology and Diabetes is a fully comprehensive, evidence-based, and highly-valued reference work combining basic science with clinical guidance, and providing first rate advice on diagnosis and treatment.

Handbook of Clinical Obstetrics

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Publisher : John Wiley & Sons
ISBN 13 : 1405171847
Total Pages : 600 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Handbook of Clinical Obstetrics by : E. Albert Reece, MD, PhD, MBA

Download or read book Handbook of Clinical Obstetrics written by E. Albert Reece, MD, PhD, MBA and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this quick reference handbook for obstetricians and gynecologists and primary care physicians is designed to complement the parent textbook Clinical Obstetrics: The Fetus & Mother The third edition of Clinical Obstetrics: The Fetus & Mother is unique in that it gives in-depth attention to the two patients – fetus and mother, with special coverage of each patient. Clinical Obstetrics thoroughly reviews the biology, pathology, and clinical management of disorders affecting both the fetus and the mother. Clinical Obstetrics: The Fetus & Mother - Handbook provides the practising physician with succinct, clinically focused information in an easily retrievable format that facilitates diagnosis, evaluation, and treatment. When you need fast answers to specific questions, you can turn with confidence to this streamlined, updated reference.

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Papillomaviruses and Human Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 3642710972
Total Pages : 527 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Papillomaviruses and Human Disease by : Kari J. Syrjänen

Download or read book Papillomaviruses and Human Disease written by Kari J. Syrjänen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, papillomaviruses in general and human papillo maviruses in particular have been recognized as possible agents of important diseases, including some forms of human cancer. The purpose of this book is to present a concise panorama of the pre sent status of knowledge of this topic. This knowledge is as impor tant to molecular biologists and virologists as it is to clinicians and pathologists. To bridge the gap among these diverse groups of investigators, we conceived of a book covering a broad spectrum of the basic scientific, clinical, and pathological aspects of diseases associated with papillomaviruses. Although the principal thrust of this book is directed at human papillomaviruses, fundamental knowledge of animal viruses is essential to the current understand ing of the molecular mechanisms of cell transformation. For this reason, a chapter on animal viruses has also been included. Some of the experimental work having to do with the elucidation of transformation and other aspects of interaction between the virus and the cell cannot be based on human papillomaviruses because of a lack of suitable experimental models. Hence, some of the chapters dealing with fundamental aspects of viral molecular biol ogy are based on animal models. We were very fortunate in having persuaded a number of distin guished colleagues to contribute to this work.

Imaging of Orbital and Visual Pathway Pathology

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Publisher : Springer Science & Business Media
ISBN 13 : 354027989X
Total Pages : 454 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Imaging of Orbital and Visual Pathway Pathology by : Wibke S. Müller-Forell

Download or read book Imaging of Orbital and Visual Pathway Pathology written by Wibke S. Müller-Forell and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with imaging of pathology of the visual system. This book is divided into two parts, general and special. In the general part, important basics of modern imaging methods are discussed. The knowledge on the indication, technique, and results of functional MR imaging is also presented.

Seizures and Epilepsy

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Publisher : Oxford University Press
ISBN 13 : 019532854X
Total Pages : 737 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Seizures and Epilepsy by : Jerome Engel Jr

Download or read book Seizures and Epilepsy written by Jerome Engel Jr and published by Oxford University Press. This book was released on 2013-01-31 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Tumor Immunology and Immunotherapy - Cellular Methods Part B

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Author :
Publisher : Academic Press
ISBN 13 : 0128186763
Total Pages : 588 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Tumor Immunology and Immunotherapy - Cellular Methods Part B by :

Download or read book Tumor Immunology and Immunotherapy - Cellular Methods Part B written by and published by Academic Press. This book was released on 2020-01-29 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy – Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more. Contains content written by authorities in the field Provides a comprehensive view on the topics covered Includes a high level of detail

Toxicologic Pathology for Non-Pathologists

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Author :
Publisher : Springer Nature
ISBN 13 : 1493997777
Total Pages : 919 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Toxicologic Pathology for Non-Pathologists by : Thomas J. Steinbach

Download or read book Toxicologic Pathology for Non-Pathologists written by Thomas J. Steinbach and published by Springer Nature. This book was released on 2019-10-31 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

Movement Disorder Emergencies

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Publisher : Springer Science & Business Media
ISBN 13 : 1592599028
Total Pages : 250 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Movement Disorder Emergencies by : Steven J. Frucht

Download or read book Movement Disorder Emergencies written by Steven J. Frucht and published by Springer Science & Business Media. This book was released on 2008-02-10 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Movement Disorder Emergencies: Diagnosis and Treatment provides a fresh and unique approach to what is already a high-profile subspecialty area in clinical neurology. The disorders covered in this volume are standard fare in the field but emphasize the urgencies and emergencies that can occur. One of the very attractive features of the field of movement disorders is that diagnosis is often based on unique visible and sometimes audible phenomenological symptoms and signs. Therefore, in this era of highly sophisticated laboratory and radiological diagnostic tools, the diagnosis of many movement disorders is still largely made in the clinic where pattern recognition is key. Crucial to astute clinical diagnosis is broad clinical experience. In short, you have to have seen one to recognize one! Patients with movement disorders nearly always present as outpatients but, as aptly recognized by Drs. Frucht and Fahn, this may include acute manifestations leading to emergency presentations, often in an emergency room setting, where they are very likely to be unrecognized and therefore poorly managed. The authors define an “emergency” movement disorder as one in which failure to promptly diagnose and treat may result in significant morbidity or mortality. However, they also stress the importance of certain “can’t miss” diagnoses such as Wilson’s disease, dopa-responsive dystonia, and Whipple’s disease in which delayed diagnosis in less emergent situations can lead to slowly evolving and often irreversible neurological damage with tragic consequences.