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Histocompatibility
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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis The HLA Complex in Biology and Medicine by : Narinder K Mehra
Download or read book The HLA Complex in Biology and Medicine written by Narinder K Mehra and published by Boydell & Brewer Ltd. This book was released on 2010-11-26 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the HLA (Human Leukocyte Antigen) system for immunologists and clinicians, this book contains up-to-date information on the MHC (Major Histocompatibility Complex) and its role in the immune response and in various diseases. The book explores the biological significance and role of the HLA system in organ and haematopoietic stem cell transplantation management. This volume is an invaluable guide to the full spectrum of HLA-related science while also serving as a conceptual and technical resource for those involved in HLA-related research and in clinical or surgical practice. In addition, it will be a primary point of contact for individuals working in other areas who suddenly find that their research is drawing them into the complexities of HLA genetics.
Book Synopsis The EBMT Handbook by : Nicolaus Kröger
Download or read book The EBMT Handbook written by Nicolaus Kröger and published by . This book was released on 2020-10-08 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access edition of the European Society for Blood and Marrow Transplantation (EBMT) handbook addresses the latest developments and innovations in hematopoietic stem cell transplantation and cellular therapy. Consisting of 93 chapters, it has been written by 175 leading experts in the field. Discussing all types of stem cell and bone marrow transplantation, including haplo-identical stem cell and cord blood transplantation, it also covers the indications for transplantation, the management of early and late complications as well as the new and rapidly evolving field of cellular therapies. This book provides an unparalleled description of current practices to enhance readers' knowledge and practice skills. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.
Book Synopsis The Major Histocompatibility Complex Region of Domestic Animal Species by : Lawrence B. Schook
Download or read book The Major Histocompatibility Complex Region of Domestic Animal Species written by Lawrence B. Schook and published by CRC Press. This book was released on 1996-08-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (Mhc) is one of the few identified gene systems in domestic animals that is associated with quantitative traits such as disease resistance, immune response, growth, and reproduction. As knowledge of this important system increases, we move closer toward the reality of genetic enhancement of animal welfare and production efficiency. This book represents the current state of knowledge on the Mhc of agriculturally important animals and explores the latest advances in technology. For the first time, the unique findings of recent Mhc research are presented in a single source. The Major Histocompatibility Complex Region of Domestic Animal Species begins with a discussion of the evolution of Mhc. The chapters are then organized with respect to specific species, with a chapter devoted to each. The Mhc of mice and humans are used as a common reference for comparisons between diverse species. The text concludes with a look at future strategies and directions in Mhc research. Comparative immunologists and geneticists, veterinarians, animal breeders, researchers, and university and postgraduate students will all benefit from this detailed look at the evolution, structure, and organization of Mhc.
Download or read book The HLA System written by John Lee and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume documents our growing understanding of the human major histocompatibility complex. The application of this information is ever more important as the limits of transplantation continue to be reduced, including the recent success of bone marrow transplantation between unrelated but closely matched individuals. In addition, the need to transfuse platelets in the face of immunologic barriers continues to challenge transfusion services. Thus, the serologic information summarized in this volume is essential for optimal patient care. At the same time, recombinant DNA technology has led to a revolution in our understanding of many aspects of basic biology. Among the advances has been the initial characterization of the structure of some HLA loci. While this will ultimately improve clinical services, constant reference to serologic data is essential so that the powerful new techniques can be applied in the most effective ways. The timing of the First Red Cross International Histocompatibility Workshop is fortunate as it brings together experts from around the world to address the state of the art. We are all grateful to Dr. John Lee and his colleagues for organizing the workshop, and for bringing together in this volume the material to be presented in Beijing during October 17-23, 1990. Leon W. Hoyer, M.D.
Book Synopsis Histocompatibility by : George Snell
Download or read book Histocompatibility written by George Snell and published by Elsevier. This book was released on 2012-12-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Histocampatibility covers the genetic, immunologic, and the chemical studies on allograft rejection process. The book is composed of 13 chapters that describe how these studies relate to medicine, organ transplantation in man, basic immunology, cell membrane structures, and cancer research. After briefly dealing with the early studies on isografts and allografts in laboratory animals, the book describes the histogenetic methods of gene manipulation and transplantation that permit identification of individual histocompatibility loci. The following chapter examines the significance of congenic resistant lines in determining the diversity of histocompatibility loci and allele and immune response genes. Other chapters present immunogenetic and serological methods, as well as the applications of these methods in studying alloantigens and H-2 complex loci and of immunogenetic methods to human. The book also discusses the practical implication of HLA immunogenetics in organ transplantation and describes the biochemical, immunochemical, and dynamic properties of alloantigens. A chapter discusses the associations between HLA system and disease and the various mechanisms that have been suggested to explain these associations. The last chapter focuses on allograft reaction and on established facts of cellular immunity. This book is a valuable source of information for researchers in the fields of medicine, organ transplantation in man, basic immunology, cell membrane structures, and cancer.
Book Synopsis Histocompatibility by : Bahaa Abdel-Salam
Download or read book Histocompatibility written by Bahaa Abdel-Salam and published by BoD – Books on Demand. This book was released on 2012-05-02 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents some recent researches related to histocompatibility for scientists interested in this field. It includes 10 chapters, in different topics, prepared by Sundararajulu Panneerchelvam and Mohd Nor Norazmi; Giada Amodio and Silvia Gregori; Adema Ribic; Bahaa K. A. Abdel-Salam; Kai-Fu Tang; Roberto Biassoni, Irene Vanni and Elisabetta Ugolotti; Wei-Cheng Yang, Lien-Siang Chou and Jer-Ming Hu; Shatrah Othman and Rohana Yusof; Masahiro Hirayama, Eiichi Azuma and Yoshihiro Komada; Gustav Roder, Linda Geironson, Elna Follin, Camilla Thuring and Kajsa Paulsson.
Book Synopsis Minor Histocompatibility Antigens by : Derry Roopenian
Download or read book Minor Histocompatibility Antigens written by Derry Roopenian and published by CRC Press. This book was released on 1999-08-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the widespread application of solid tissue and bone marrow transplantation as a treatment for an array of life threatening disorders, there is a pressing need for clinicians and experimentalists to understand the basis of immunological rejection of tissue transplants. While much previous work focuses on characterization of antigens encoded by
Book Synopsis Histocompatibility Testing by : Jeffrey L Bidwell
Download or read book Histocompatibility Testing written by Jeffrey L Bidwell and published by World Scientific. This book was released on 2000-03-08 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable book provides comprehensive coverage of contemporary serological, cellular and molecular methodologies in histocompatibility testing, and their application to human organ transplantation and transfusion. The contributors are internationally respected authorities in histocompatibility and immunogenetics, and are closely involved in the development or application of state-of-the-art technologies. The first three sections of the book are primarily intended for use as a bench manual for histocompatibility testers, immunologists and immunogeneticists; the fourth and fifth sections, on selection of donors and statistical methods, will further assist medical practitioners involved in clinical transplantation and its outcome. The final section of the book reviews the genetics and clinical relevance of minor histocompatibility antigens. Contents: Foreword:HLA Polymorphism: Origin and Maintenance (W F Bodmer)Introduction:Immune Recognition and the MHC (P Travers)Antibody-Based Histocompatibility Testing:HLA Typing by Alloantibodies and Monoclonal Antibodies (G M Th Schreuder)Screening for HLA-Specific Antibodies (C Brown & C Navarrete)Detection of Soluble HLA (V Rebmann & H Grosse-Wilde)Crossmatching by Lymphocytotoxicity and Flow Cytometry (S Martin & A Harmer)DNA-Based Histocompatibility Testing:PCR-SSP Typing (M Bunce)PCR-SSOP Typing (D Middleton)Sequencing-Based Typing (J Ross)DNA Conformational Analysis (J R Argüello & J A Madrigal)Microsatellite Typing (A Cambon-Thomsen et al.)On-Line HLA Sequence Alignments (G J Laundy & J L Bidwell)Cell-Based Histocompatibility Testing:Cell-Based Histocompatibility Testing (E Kaminski)Donor Selection:Allocation of Solid Organs for Transplantation (P A Dyer & S Sheldon)Selection of Haemopoietic Stem Cell Donors for Transplantation (A Green)Selection of Platelet Donors and Provision of HLA-Matched Platelets (J Harrison & C Navarrete)Statistical Methods:Population Genetics of the Human Major Histocompatibility Complex (R F Schipper et al.)Survival Analysis in Solid Organ Transplantation (P A Dyer)Survival Analysis in Bone Marrow Transplantation (S Richards)HLA and Disease Association: Statistical Considerations(J H Barrett et al.)Minor Histocompatibility Antigens:Minor Histocompatibility Antigens (E Simpson) Readership: Researchers in immunology, histopathology, cell biology and genetics, surgeons and workers in blood transfusion. Keywords:Immunology;Genetics;Immunogenetics;Transplantation;Histocompatibility;Tissue Typing;Human Leucocyte Antigens, HLA;Major Histocompatibility Complex, MHC;Laboratory Methods
Book Synopsis Current Trends in Histocompatibility by : Ralph Reisfeld
Download or read book Current Trends in Histocompatibility written by Ralph Reisfeld and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information about histocompatibility antigens is expanding so rapidly that it is difficult to remain abreast of aB advances. In these volumes, we have made an effort to bring together the most current work on topics that have generated most of the re cent advances and discussions. We have asked each author to present and interpret his most current work, and we have judiciously refrained from imposing our own prejudices and viewpoints. Although there is obvious overlap in some individual topics, we have encouraged this to provide the reader with as many different and some times opposing viewpoints as possible. This approach will, we liope, give a broad overview of current ideas in the field. We wish to thank all contributors for their timely and exciting manu scripts, and we sincerely hope that the reader will benefit from these volumes. R. A. Reisfeld S. Ferrone La Jolla ix Contents I. Serology and Genetics Chapter 1 Studies of HLA-DR Antigens by Complement Fixation Jacques M. Colombani, Laurent Degos, Virginia Lepage, Helene Dastot, Muriel Reboul, and Pierre Lethielleux 1. Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. Material and Methods. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3. Results and Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3. 1. Screening for Anti-HLA-DR Complement-Fixing Sera . . . . . . . . 4 3. 2. Expression of HLA-A, -B and -DR Antigens on Peripheral Blood Lymphocytes during Phytohemagglutinin Stimulation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 3. 3. Expression of HLA-A, -B and -DR Antigens on Peripheral Blood Lymphocytes during Concanavalin A Stimulation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 3. 4.
Book Synopsis Genetics of Human Histocompatibility Antigens and Their Relation to Disease by : E. Thorsby
Download or read book Genetics of Human Histocompatibility Antigens and Their Relation to Disease written by E. Thorsby and published by Ardent Media. This book was released on 1973 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Histocompatibility Testing 1984 by : E.D. Albert
Download or read book Histocompatibility Testing 1984 written by E.D. Albert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Major Histocompatibility Complex (MHC) in Health and Disease by : Jerzy K. Kulski
Download or read book Major Histocompatibility Complex (MHC) in Health and Disease written by Jerzy K. Kulski and published by MDPI. This book was released on 2020-01-15 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.
Book Synopsis The Major Histocompatibility System in Man and Animals by : D. Götze
Download or read book The Major Histocompatibility System in Man and Animals written by D. Götze and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biology of the Mouse Histocompatibility-2 Complex by : J. de Klein
Download or read book Biology of the Mouse Histocompatibility-2 Complex written by J. de Klein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Somewhere I heard a story of a bridge and a painter. The bridge was enormous and was made all of metal, and the painter's job was to keep it from rusting. He would start at one end and slowly proceed, day by day, month by month, toward the other end, painting the bridge. But no sooner would he finish with the painting than the bridge would begin to rust again. The rust, too, would start at one end and slowly proceed toward the other end, systematically destroying the painter's endeavor. And so the painter would return to where he had started, and begin painting again, slowly proceeding toward the other end of the bridge, always just one step ahead of the rust. And if the story is true, the painter might still be painting that bridge-a modern Sisyphus! During the writing of this book, the story of the painter and his bridge kept coming to mind. The field the book covers has been developing so rapidly that, like the painter, I too had to return to where I had started and fight the rust of obsolescence. But unlike the painter, I had a deadline to meet, which constituted a point of no return. And so, sending off this manuscript, I have no choice but to watch the fruits of my endeavor be overtaken by the rust.
Book Synopsis Major Histocompatibility Complex by : M. Kasahara
Download or read book Major Histocompatibility Complex written by M. Kasahara and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every biological system is the outcome of evolution and has a history all its own. This history dictates how the system works and why it has certain properties and not others. This is why we need to study not only the structure and function, but also the history of the system. This argument undoubtedly applies to the study of the immune system and also to the study of the major histocompatibility complex (MHC). Since 1989, researchers of various scientific disciplines who share a deep inter est in MHC evolution have held a meeting every two years to discuss their latest research developments, exchange ideas, and foster friendship. Together with my colleagues Drs. Naoyuki Takahata and Yoko Satta, I organized the Sixth Interna tional Workshop on MHC Evolution in Hayama, Japan, May 25-29, 1999. This volume is the proceedings of that conference. It covers diverse topics pertinent to MHC evolution, including the origin of the adaptive immune system, the organi zation of the MHC in humans and other model vertebrates, MHC-parasite co evolution, and the nature and origin of MHC polymorphism. I hope that this book will be of interest not only for MHC researchers and immunologists, but also for other specialists who are interested in the evolution of biological systems in gen eral.
Book Synopsis Molecular Evolution of the Major Histocompatibility Complex by : Jan Klein
Download or read book Molecular Evolution of the Major Histocompatibility Complex written by Jan Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: From molecules to populations and back In biology, the most vigorous organisms often ensue from a union of two disparate, pure lines. In science, too, laws of hybrid vigor seem to operate at the interface between two disciplines, an interface that often proves to be fertile ground for germinating concepts and new outlooks. The fringes of research into the major histocompatibility complex (Mhc) have provided such an interface several times in the past and the encounters have invigorated fields such as transplantation biology, cellular immunology, and immunogenetics. In the last few years, a new interface has been emerging between Mhc and evolutionary genetics, and particularly the branch of evolutionary genetics dealing with molecular evolution. Mhc research relies upon molecular evolutionary genetics, with its grand superstructure of mathematical formulations, to come to grips with the events leading to and maintaining the Mhc polymorphism. Without the armament of rigorous statistical procedures developed by evolutionary geneticists, the intricate relationships among Mhc genes cannot be resolved. It will undoubtedly be a molecular geneticist who is the final arbiter in the dispute concerning the nature of the selection pressure molding the Mhc genes. And it is doubtful whether the true function of Mhc can ever be comprehended without the vantage point afforded by the elucidation of its evolutionary history.
