Highly Selective Separations In Biotechnology

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Highly Selective Separations in Biotechnology

Author : G. Street
Publisher : Springer Science & Business Media
ISBN 13 : 940111322X
Total Pages : 242 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Highly Selective Separations in Biotechnology by : G. Street

Download or read book Highly Selective Separations in Biotechnology written by G. Street and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success in meeting the challenge to produce the commercial products anticipated by the exploitation of biological processes depends upon provid ing effective separation protocols. Effectiveness can be measured in terms of selectivity, purity, resolution and validatory success. The major processing problems are associated with either the selective recovery of molecules which are present in low concentrations from complex mixtures or the selective removal of contaminants from the desired molecule. Central to the evolution of processes satisfying this demand are the regulatory requirements being imposed by governments on the purity of a product, especially in the health care market. Synthetic organic chemists are increasingly finding it advantageous to conduct one or more steps using either enzymic biotransformations where molecules with a single and consistent stereochemistry or chirality are required. The underlying princi ples behind the methods, techniques and processes currently being used and developed commercially rely upon the biospecific nature and properties of the desired molecule. When these factors are married to the more traditional techniques of precipitation, chromatography, liquid-liquid extraction and membrane processes, powerful tools emerge, allowing highly selective separations to be designed. The logical extension of these combinations is to apply genetic engineering techniques to influence the separations at a more fundamental and structural level by modifying the target protein at source, during its synthesis, to facilitate its separation in a given, selective manner, leading to the distinct possibility of producing 'designer' separation programmes.

Separation Processes

Author : R. A. Betts
Publisher :
ISBN 13 : 9781870669658
Total Pages : 32 pages
Book Rating : 4.6/5 (696 download)

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Book Synopsis Separation Processes by : R. A. Betts

Download or read book Separation Processes written by R. A. Betts and published by . This book was released on 1988 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Separations for Biotechnology 2

Author : D. Leo Pyle
Publisher : Springer Science & Business Media
ISBN 13 : 9400907834
Total Pages : 659 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Separations for Biotechnology 2 by : D. Leo Pyle

Download or read book Separations for Biotechnology 2 written by D. Leo Pyle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 659 pages. Available in PDF, EPUB and Kindle. Book excerpt: The challenge of bioseparations is to isolate and purify identified products from the dilute product broth produced from cell culture. Innovation in bioseparations technology is increasingly driven by the requirements imposed by the growing importance of production on a process scale of injectable-grade products, and economic pressures to improve the efficiency of downstream processing. As in other areas of technical change, science does not necessarily precede new technology: progress results from a complex and messy mixture of advances in understanding, ingenious ideas, novel techniques and chance discoveries. What is certain is that close interaction between academics and practitioners, biological scientists and process engineers is needed to solve the problems of bioseparations. The Second International Conference on Separations for Biotechnology at Reading, UK, in September 1990 set out to provide a critical multidisciplinary forum for the discussion of bioseparations. This volume contains the papers presented at the meeting. The meeting was organised around six themes with oral and poster presentations on the science and practice of bioseparations technology, and the same structure has been kept for this book. We have also included the texts of the keynote review paper by Professor Alan Michaels and the introductory review papers specially commissioned for the conference. Within each part of this book the review paper is followed by the contributed papers grouped alphabetically by their first author. All the original papers published here were accepted for publication after scientific refereeing.

Membrane Separations in Biotechnology

Author : William K. Wang
Publisher : CRC Press
ISBN 13 : 1482289881
Total Pages : 432 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Membrane Separations in Biotechnology by : William K. Wang

Download or read book Membrane Separations in Biotechnology written by William K. Wang and published by CRC Press. This book was released on 2001-04-03 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text details the relationship between membrane technology and bioprocesses, discussing applications. This second edition refines and optimizes key features of the first edition - and features new illustrative case studies. The book examines advantages and disadvantages of using standard and new membrane technologies; analyzes a wide range of a

Methods for Affinity-Based Separations of Enzymes and Proteins

Author : Munishwar N. Gupta
Publisher : Birkhäuser
ISBN 13 : 3034881274
Total Pages : 234 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Methods for Affinity-Based Separations of Enzymes and Proteins by : Munishwar N. Gupta

Download or read book Methods for Affinity-Based Separations of Enzymes and Proteins written by Munishwar N. Gupta and published by Birkhäuser. This book was released on 2013-12-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.

Separation Processes in Biotechnology

Author : Juan A. Asenjo
Publisher : CRC Press
ISBN 13 : 1000147533
Total Pages : 828 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Separation Processes in Biotechnology by : Juan A. Asenjo

Download or read book Separation Processes in Biotechnology written by Juan A. Asenjo and published by CRC Press. This book was released on 2020-08-26 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited to avoid duplication and favor comprehensiveness, 20 contributors detail the recovery, separation, and purification operations of bioprocess technology. Individual chapters in this classic yet still highly relevant work emphasize concepts that are becoming more and more important when applied to the large scale versions of techniques that are considered well established. Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery. It also discusses plant operation and equipment and delves into economic considerations

Separations for Biotechnology

Author :
Publisher :
ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Separations for Biotechnology by :

Download or read book Separations for Biotechnology written by and published by . This book was released on 1990 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Separation Processes in the Food and Biotechnology Industries

Author : A S Grandison
Publisher : Woodhead Publishing
ISBN 13 : 9781855732872
Total Pages : 306 pages
Book Rating : 4.7/5 (328 download)

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Book Synopsis Separation Processes in the Food and Biotechnology Industries by : A S Grandison

Download or read book Separation Processes in the Food and Biotechnology Industries written by A S Grandison and published by Woodhead Publishing. This book was released on 1996-01-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews methods and techniques for separating food components and products of the biotechnology industry. The introduction focuses on food composition and some of the conventional separation techniques. Subsequent chapters deal with each specific type or area of application individually and include information on the basic principles, industrial equipment available, commercial applications and an overview of research and development.

Separations Technology

Author : Wayne P. Olson
Publisher : CRC Press
ISBN 13 : 1000717224
Total Pages : 526 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Separations Technology by : Wayne P. Olson

Download or read book Separations Technology written by Wayne P. Olson and published by CRC Press. This book was released on 2020-02-03 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by a team of respected scientists and technologists, this book covers many pharmaceutical and biotechnology separations methods currently in use. Practical applications and descriptions are offered for air elutriation, microporous filtration, ultrafiltration, phase partitioning, crystallization, and chromatographic technologies such as adsorption, affinity, chelate, ion-exchange, size-exclusion, template, hydrophobic interaction, biotransformations, and chiral separations. Containing hundreds of references and a complete index, this book is designed for research and development scientists, process optimization engineers, and quality control laboratory scientists as well as quality assurance professionals and others needing to understand current separation techniques.

Separations for Biotechnology

Author : M. S. Verrall
Publisher :
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Separations for Biotechnology by : M. S. Verrall

Download or read book Separations for Biotechnology written by M. S. Verrall and published by . This book was released on 1987 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural-Based Polymers for Biomedical Applications

Author : Rui L. Reis
Publisher : Elsevier
ISBN 13 : 1845694813
Total Pages : 832 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Natural-Based Polymers for Biomedical Applications by : Rui L. Reis

Download or read book Natural-Based Polymers for Biomedical Applications written by Rui L. Reis and published by Elsevier. This book was released on 2008-08-15 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering. The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility. Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. Examines the sources, processing and properties of natural based polymers for biomedical applications Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine

Downstream Processing in Biotechnology

Author : Venko N. Beschkov
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 311057411X
Total Pages : 177 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Downstream Processing in Biotechnology by : Venko N. Beschkov

Download or read book Downstream Processing in Biotechnology written by Venko N. Beschkov and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-06-21 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book gives an excellent insight into downstream processing technology and explains how to establish a successful strategy for an efficient recovery, isolation and purification of biosynthetic products. In addition to the overview of purification steps and unit operations, the authors provide practical information on capital and operating costs related to downstream processing.

Smart Polymers and their Applications

Author : Maria Rosa Aguilar
Publisher : Elsevier
ISBN 13 : 0857097024
Total Pages : 587 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Smart Polymers and their Applications by : Maria Rosa Aguilar

Download or read book Smart Polymers and their Applications written by Maria Rosa Aguilar and published by Elsevier. This book was released on 2014-02-19 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart polymers are polymers that respond to different stimuli or changes in the environment. Smart Polymers and their Applications reviews the types, synthesis, properties, and applications of smart polymers. Chapters in part one focus on types of polymers, including temperature-, pH-, photo-, and enzyme-responsive polymers. Shape memory polymers, smart polymer hydrogels, and self-healing polymer systems are also explored. Part two highlights applications of smart polymers, including smart instructive polymer substrates for tissue engineering; smart polymer nanocarriers for drug delivery; the use of smart polymers in medical devices for minimally invasive surgery, diagnosis, and other applications; and smart polymers for bioseparation and other biotechnology applications. Further chapters discuss the use of smart polymers for textile and packaging applications, and for optical data storage. Smart Polymers and their Applications is a technical resource for chemists, chemical engineers, mechanical engineers, and other professionals in the polymer industry; manufacturers in such sectors as medical, automotive, and aerospace engineering; and academic researchers in polymer science. Reviews the different types of smart polymer, discussing their properties, structure, design, and characterization Reviews applications of smart polymers in such areas as biomedical engineering, textiles, and food packaging

Industrial Membrane Separation Technology

Author : K. Scott
Publisher : Springer Science & Business Media
ISBN 13 : 9780751403381
Total Pages : 326 pages
Book Rating : 4.4/5 (33 download)

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Book Synopsis Industrial Membrane Separation Technology by : K. Scott

Download or read book Industrial Membrane Separation Technology written by K. Scott and published by Springer Science & Business Media. This book was released on 1996 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although membrane separations can now routinely replace traditional separations, there is a need for the new developments in the applications and theories of membrane separation to be transmitted to industry to continue the drive forward in membrane development. This book presents new developments in the context of industrial technology and relates the principles of design to plant set-up and equipment selection.

Isolation and Purification of Proteins

Author : Rajni Hatti-Kaul
Publisher : CRC Press
ISBN 13 : 9780203911686
Total Pages : 688 pages
Book Rating : 4.9/5 (116 download)

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Book Synopsis Isolation and Purification of Proteins by : Rajni Hatti-Kaul

Download or read book Isolation and Purification of Proteins written by Rajni Hatti-Kaul and published by CRC Press. This book was released on 2003-02-05 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication details the isolation of proteins from biological materials, techniques for solid-liquid separation, concentration, crystallization, chromatography, scale-up, process monitoring, product formulation, and regulatory and commercial considerations in protein production. The authors discuss the release of protein from a biological host, selectivity in affinity chromatography, precipitation of proteins (both non-specific and specific), extraction for rapid protein isolation, adsorption as an initial step for the capture of proteins, scale-up and commercial production of recombinant proteins, and process monitoring in downstream processing.

Handbook of Membrane Separations

Author : Anil K. Pabby
Publisher : CRC Press
ISBN 13 : 0849395496
Total Pages : 1210 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Handbook of Membrane Separations by : Anil K. Pabby

Download or read book Handbook of Membrane Separations written by Anil K. Pabby and published by CRC Press. This book was released on 2008-07-07 with total page 1210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological Applications provides detailed information on membrane separation technologies as they have evolved over the past decades. To provide a basic understanding of membrane technology, this book documents the developments dealing with these technologies. It explores chemical, pharmaceutical, food processing and biotechnological applications of membrane processes ranging from selective separation to solvent and material recovery. This text also presents in-depth knowledge of membrane separation mechanisms, transport models, membrane permeability computations, membrane types and modules, as well as membrane reactors.

Handbook of Membrane Separations

Author : Anil K. Pabby
Publisher : CRC Press
ISBN 13 : 1003811574
Total Pages : 601 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Handbook of Membrane Separations by : Anil K. Pabby

Download or read book Handbook of Membrane Separations written by Anil K. Pabby and published by CRC Press. This book was released on 2023-12-22 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the Handbook of Membrane Separations: Chemical, Pharmaceutical, Food, and Biotechnological Applications provides a comprehensive discussion of membrane applications. Fully updated to include the latest advancements in membrane science and technology, it is a one-of-its-kind overview of the existing literature. This fully illustrated handbook is written by experts and professionals in membrane applications from around the world. Key Features: Includes entirely new chapters on organic solvent-resistant nanofiltration, membrane condensers, membrane-reactors in hydrogen production, membrane materials for haemodialysis, and integrated membrane distillation Covers the full spectrum of membrane technology and its advancements Explores membrane applications in a range of fields, from biotechnological and food processing to industrial waste management and environmental engineering This book will appeal to both newcomers to membrane science as well as engineers and scientists looking to expand their knowledge on upcoming advancements in the field.