Heterocyclic Anti Inflammatory Agents A Guide For Medicinal Chemists

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Heterocyclic Anti-Inflammatory Agents

Author : Anjaneyulu Bendi;
Publisher :
ISBN 13 : 9789815223484
Total Pages : 0 pages
Book Rating : 4.2/5 (234 download)

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Book Synopsis Heterocyclic Anti-Inflammatory Agents by : Anjaneyulu Bendi;

Download or read book Heterocyclic Anti-Inflammatory Agents written by Anjaneyulu Bendi; and published by . This book was released on 2024-05-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the cutting-edge experimental research on heterocyclic compounds used as anti-inflammatory agents in ten chapters. Each chapter is authored by experts in medicinal chemistry and is supplemented with scientific references for advanced reading. The book covers several types of heterocyclic compounds and their derivatives including · pyrimidine and pyrimidinone derivatives · 1,2,3, and 1,2,4 triazoles · imidazole and benzimidazole derivatives · oxazole, oxadiazole, isoxazoline, and oxazoline derivatives · thiazole and thiazolidinone derivatives · pyrazole and pyrazoline · carbazoles and their derivatives · azipines, quinolines, and coumarins This is a timely reference for medicinal chemists interested in developing new heterocycles for anti-inflammatory drugs. Contributors have discussed the effects of these compounds on different types of inflammation and their evolution in drug development as a therapeutic agent to give a wider perspective to readers.

Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists

Author : Anjaneyulu Bendi
Publisher : Bentham Science Publishers
ISBN 13 : 981522347X
Total Pages : 248 pages
Book Rating : 4.8/5 (152 download)

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Book Synopsis Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists by : Anjaneyulu Bendi

Download or read book Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists written by Anjaneyulu Bendi and published by Bentham Science Publishers. This book was released on 2024-05-24 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the cutting-edge experimental research on heterocyclic compounds used as anti-inflammatory agents in ten chapters. Each chapter is authored by experts in medicinal chemistry and is supplemented with scientific references for advanced reading. The book covers several types of heterocyclic compounds and their derivatives including : - pyrimidine and pyrimidinone derivatives - 1,2,3, and 1,2,4 triazoles - imidazole and benzimidazole derivatives - oxazole, oxadiazole, isoxazoline, and oxazoline derivatives - thiazole and thiazolidinone derivatives - pyrazole and pyrazoline - Carbazoles and their derivatives - azipines, quinolines, and coumarins This is a timely reference for medicinal chemists interested in developing new heterocycles for anti-inflammatory drugs. Contributors have discussed the effects of these compounds on different types of inflammation and their evolution in drug development as therapeutic agents to give a wider perspective to readers.

Vicinal Diaryl Substituted Heterocycles

Author : M. R. Yadav
Publisher : Elsevier
ISBN 13 : 0081022492
Total Pages : 432 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Vicinal Diaryl Substituted Heterocycles by : M. R. Yadav

Download or read book Vicinal Diaryl Substituted Heterocycles written by M. R. Yadav and published by Elsevier. This book was released on 2018-03-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules. - Collects together details of the key vicinal diaryl-substituted heterocyclic compounds in one place for the first time - Highlights biological activities and SAR of derivatives - Structured practically for ease of navigation between different derivatives

Key Heterocycle Cores for Designing Multitargeting Molecules

Author : Om Silakari
Publisher : Elsevier
ISBN 13 : 0081021054
Total Pages : 438 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Key Heterocycle Cores for Designing Multitargeting Molecules by : Om Silakari

Download or read book Key Heterocycle Cores for Designing Multitargeting Molecules written by Om Silakari and published by Elsevier. This book was released on 2018-06-11 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research. - Emphasizes the chemical development of heterocyclic nuclei, from single to multitargeting molecules - Provides chapter-by-chapter coverage of the key heterocyclic compounds used in synthesizing multitargeting agents - Outlines current trends and future developments in multitarget molecule design for the treatment of various diseases

Bioactive Heterocycles

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (123 download)

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Book Synopsis Bioactive Heterocycles by :

Download or read book Bioactive Heterocycles written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heat Shock Protein Inhibitors

Author : Shelli R. McAlpine
Publisher : Springer
ISBN 13 : 3319326074
Total Pages : 243 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Heat Shock Protein Inhibitors by : Shelli R. McAlpine

Download or read book Heat Shock Protein Inhibitors written by Shelli R. McAlpine and published by Springer. This book was released on 2016-05-23 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Biologically Active Peptides

Author : Fidel Toldra
Publisher : Academic Press
ISBN 13 : 0128214384
Total Pages : 819 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Biologically Active Peptides by : Fidel Toldra

Download or read book Biologically Active Peptides written by Fidel Toldra and published by Academic Press. This book was released on 2021-06-17 with total page 819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology. - Discusses the latest advances in bioactive peptide chemistry, functionality and analysis - Offers step-by-step instruction in applying new technologies for peptide extraction, protection, production and encoding, as well as employing bioactive peptide sequencing and bioactivity assays in new research - Effectively links basic peptide chemistry, human biology and disease - Features chapter contributions from international experts across disciplines and applications

Recent Trends in Human and Animal Mycology

Author : Karuna Singh
Publisher : Springer Nature
ISBN 13 : 9811394350
Total Pages : 289 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Recent Trends in Human and Animal Mycology by : Karuna Singh

Download or read book Recent Trends in Human and Animal Mycology written by Karuna Singh and published by Springer Nature. This book was released on 2019-11-06 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal pathogens pose an on-going and serious threat for poikilotherms and homeotherms, and can cause a broad spectrum of diseases ranging from innocuous to life-threatening. In addition, long-term exposure to some mycotoxigenic moulds can lead to mycotoxicoses in human and animals. Given the expanding population of immune compromised hosts, the list of fungal opportunists grows longer every year. Moreover, antifungal resistance, drug-related toxicity and our limited arsenal of antifungals have exacerbated the situation. To address these problems, strategies such as the identification of novel targets, use of the structure-activity relationship in rational drug design, development of new formulations, modification of existing antifungals to combat resistance, and bioavailability enhancement are called for. For the reader’s convenience, this book has been divided into three sections. The first six chapters of Section I provide a timely review of mycoses, from endemic to cosmopolitan and from generalized to specific, while both chapters of Section II focus on risks associated with mycotoxins. In closing, the two chapters of Section III describe potential antifungal leads and drug candidates based on phytochemicals and coumarin scaffold.

Textbook of Organic Medicinal and Pharmaceutical Chemistry

Author : Charles Owens Wilson
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 1150 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Textbook of Organic Medicinal and Pharmaceutical Chemistry by : Charles Owens Wilson

Download or read book Textbook of Organic Medicinal and Pharmaceutical Chemistry written by Charles Owens Wilson and published by Lippincott Williams & Wilkins. This book was released on 1977 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Comprehensive Guide to Nanoparticles in Medicine

Author : Rituparna Acharya
Publisher : Bentham Science Publishers
ISBN 13 : 1681088363
Total Pages : 199 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis A Comprehensive Guide to Nanoparticles in Medicine by : Rituparna Acharya

Download or read book A Comprehensive Guide to Nanoparticles in Medicine written by Rituparna Acharya and published by Bentham Science Publishers. This book was released on 2021-06-28 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.

Chemistry for Pharmacy Students

Author : Professor Satyajit D. Sarker
Publisher : John Wiley & Sons
ISBN 13 : 1118687531
Total Pages : 397 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemistry for Pharmacy Students by : Professor Satyajit D. Sarker

Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Chemical Epigenetics

Author : Antonello Mai
Publisher : Springer Nature
ISBN 13 : 3030429822
Total Pages : 569 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Chemical Epigenetics by : Antonello Mai

Download or read book Chemical Epigenetics written by Antonello Mai and published by Springer Nature. This book was released on 2020-03-31 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.

Heterocycles

Author :
Publisher :
ISBN 13 :
Total Pages : 632 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Heterocycles by :

Download or read book Heterocycles written by and published by . This book was released on 2009 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Organic Chemistry

Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 1118681967
Total Pages : 711 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Essentials of Organic Chemistry by : Paul M. Dewick

Download or read book Essentials of Organic Chemistry written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2013-03-20 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.

Medicinal Chemistry

Author : Thomas Nogrady
Publisher : Oxford University Press
ISBN 13 : 0190282967
Total Pages : 664 pages
Book Rating : 4.1/5 (92 download)

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Book Synopsis Medicinal Chemistry by : Thomas Nogrady

Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

Pharmacology in 7 Days for Medical Students

Author : Fazal-I-Akbar Danish
Publisher : CRC Press
ISBN 13 : 1138031143
Total Pages : 160 pages
Book Rating : 4.1/5 (38 download)

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Book Synopsis Pharmacology in 7 Days for Medical Students by : Fazal-I-Akbar Danish

Download or read book Pharmacology in 7 Days for Medical Students written by Fazal-I-Akbar Danish and published by CRC Press. This book was released on 2018-05-08 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacological knowledge among medical students can have a very short 'half life': students often fail not because they have failed to study, but because they have been unable to retain key knowledge and reproduce it in an exam setting. This book takes an alternative route to the conventional approach of comprehensively exploring each individual drug and its features: not only can such an approach overwhelm and make knowledge retention difficult, but the current exam format makes questions structured in this way unlikely anyway. Instead of aiming to be completely comprehensive, it examines drugs systematically by classifications, mechanisms of action, therapeutic uses and side effects, enabling students to gain the distilled, functional grasp of pharmacology that their exams actually demand quickly and clearly.

Medicinal Natural Products

Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)

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Book Synopsis Medicinal Natural Products by : Paul M. Dewick

Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.