Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists

Download Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists PDF Online Free

Author :
Publisher : Bentham Science Publishers
ISBN 13 : 981522347X
Total Pages : 248 pages
Book Rating : 4.8/5 (152 download)

DOWNLOAD NOW!


Book Synopsis Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists by : Anjaneyulu Bendi

Download or read book Heterocyclic Anti-Inflammatory Agents: A Guide for Medicinal Chemists written by Anjaneyulu Bendi and published by Bentham Science Publishers. This book was released on 2024-05-24 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the cutting-edge experimental research on heterocyclic compounds used as anti-inflammatory agents in ten chapters. Each chapter is authored by experts in medicinal chemistry and is supplemented with scientific references for advanced reading. The book covers several types of heterocyclic compounds and their derivatives including : - pyrimidine and pyrimidinone derivatives - 1,2,3, and 1,2,4 triazoles - imidazole and benzimidazole derivatives - oxazole, oxadiazole, isoxazoline, and oxazoline derivatives - thiazole and thiazolidinone derivatives - pyrazole and pyrazoline - Carbazoles and their derivatives - azipines, quinolines, and coumarins This is a timely reference for medicinal chemists interested in developing new heterocycles for anti-inflammatory drugs. Contributors have discussed the effects of these compounds on different types of inflammation and their evolution in drug development as therapeutic agents to give a wider perspective to readers.

Vicinal Diaryl Substituted Heterocycles

Download Vicinal Diaryl Substituted Heterocycles PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0081022492
Total Pages : 432 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!


Book Synopsis Vicinal Diaryl Substituted Heterocycles by : M. R. Yadav

Download or read book Vicinal Diaryl Substituted Heterocycles written by M. R. Yadav and published by Elsevier. This book was released on 2018-03-14 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules. - Collects together details of the key vicinal diaryl-substituted heterocyclic compounds in one place for the first time - Highlights biological activities and SAR of derivatives - Structured practically for ease of navigation between different derivatives

Inflammation and Natural Products

Download Inflammation and Natural Products PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128192194
Total Pages : 420 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Inflammation and Natural Products by : Sreeraj Gopi

Download or read book Inflammation and Natural Products written by Sreeraj Gopi and published by Academic Press. This book was released on 2021-01-19 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approx.446 pagesApprox.446 pages

Fundamentals of Inflammation

Download Fundamentals of Inflammation PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 1139936670
Total Pages : 489 pages
Book Rating : 4.1/5 (399 download)

DOWNLOAD NOW!


Book Synopsis Fundamentals of Inflammation by : Charles N. Serhan

Download or read book Fundamentals of Inflammation written by Charles N. Serhan and published by Cambridge University Press. This book was released on 2010-04-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acute inflammatory response is the body's first system of alarm signals that are directed toward containment and elimination of microbial invaders. Uncontrolled inflammation has emerged as a pathophysiologic basis for many widely occurring diseases in the general population that were not initially known to be linked to the inflammatory response, including cardiovascular disease, asthma, arthritis, and cancer. To better manage treatment, diagnosis, and prevention of these wide-ranging diseases, multidisciplinary research efforts are underway in both academic and industry settings. This book provides an introduction to the cell types, chemical mediators, and general mechanisms of the host's first response to invasion. World-class experts from institutions around the world have written chapters for this introductory text. The text is presented as an introductory springboard for graduate students, medical scientists, and researchers from other disciplines wishing to gain an appreciation and working knowledge of current cellular and molecular mechanisms fundamental to inflammation.

Nanobiomaterials in Galenic Formulations and Cosmetics

Download Nanobiomaterials in Galenic Formulations and Cosmetics PDF Online Free

Author :
Publisher : William Andrew
ISBN 13 : 0323428916
Total Pages : 461 pages
Book Rating : 4.3/5 (234 download)

DOWNLOAD NOW!


Book Synopsis Nanobiomaterials in Galenic Formulations and Cosmetics by : Alexandru Grumezescu

Download or read book Nanobiomaterials in Galenic Formulations and Cosmetics written by Alexandru Grumezescu and published by William Andrew. This book was released on 2016-05-12 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiomaterials in Galenic Formulations and Cosmetics: Applications of Nanobiomaterials is one of the first books on the market related to the application of nanotechnology in galenic formulations and cosmetics. This book provides the results of current research for those working in an applied setting. The advantage of having all this information in one coherent text is the focused nature of the chapters and the ease of which this information can be accessed. This collection of titles brings together many of the novel applications these materials have in biology, and discusses the advantages and disadvantages of each application and the perspectives of the technologies based on these findings. At the moment there is no other comparable book series covering all the subjects approached in this set of titles. - Offers an updated and highly structured reference material for students, researchers, and practitioners working in biomedical, biotechnological, and engineering fields - Serves as a valuable resource of recent scientific progress, along with most known applications of nanomaterials in the biomedical field - Features novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Natural-Based Polymers for Biomedical Applications

Download Natural-Based Polymers for Biomedical Applications PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 1845694813
Total Pages : 829 pages
Book Rating : 4.8/5 (456 download)

DOWNLOAD NOW!


Book Synopsis Natural-Based Polymers for Biomedical Applications by : Rui L. Reis

Download or read book Natural-Based Polymers for Biomedical Applications written by Rui L. Reis and published by Elsevier. This book was released on 2008-08-15 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine

Recent Developments in Anti-Inflammatory Therapy

Download Recent Developments in Anti-Inflammatory Therapy PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0323914160
Total Pages : 414 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Recent Developments in Anti-Inflammatory Therapy by : Parteek Prasher

Download or read book Recent Developments in Anti-Inflammatory Therapy written by Parteek Prasher and published by Academic Press. This book was released on 2023-02-17 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation. - Identifies recent developments and current trends in anti-inflammation therapy - Discusses advanced chemotherapeutics, SAR analysis of novel pharmacophores and natural products - Outlines the pathophysiology of inflammatory pathways in the pathogenesis of disease onset, including strategies to counter these intricacies - Contains a blend of editors from both academia and industry

Bioactive Heterocycles

Download Bioactive Heterocycles PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (123 download)

DOWNLOAD NOW!


Book Synopsis Bioactive Heterocycles by :

Download or read book Bioactive Heterocycles written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

S-Heterocycles

Download S-Heterocycles PDF Online Free

Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1837674868
Total Pages : 493 pages
Book Rating : 4.8/5 (376 download)

DOWNLOAD NOW!


Book Synopsis S-Heterocycles by : Shrikaant Kulkarni

Download or read book S-Heterocycles written by Shrikaant Kulkarni and published by Royal Society of Chemistry. This book was released on 2024-07-24 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds are vital in synthetic chemistry, pharmaceuticals, agrochemicals, and materials science. The concept of S-heterocyclic compounds revolves around organic compounds that contain heterocyclic rings, and sulfur (S) is one of the heteroatoms within the ring structure. S-enabled heterocycles have emerged as one of the key classes of heterocycles and have attracted tremendous attention attributed to their identity as ‘privileged pharmacological structures’ across natural products and highly active pharmaceutical agents. This edited volume reports the latest developments in practical and selective reactions and methods and provides details of the structural diversity of heterocycles. Together, the chapters provide a comprehensive view of the diversity of methods, properties, and the variety of applications in the construction of S-heterocycles. Divided into four parts, the book covers in part one the chemistry, synthesis pathways, property profile, and applications of thiazoles, and includes five chapters. Part two details thiadiazoles and part three thiopyrans, thiazine, and thiazepine. Lastly, part four focuses on thiophenes. This volume will be of immense help to academicians, researchers, and students pursuing research and looking at the future of heterocyclic chemistry.

Medicinal Plants of South Asia

Download Medicinal Plants of South Asia PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0081026609
Total Pages : 770 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!


Book Synopsis Medicinal Plants of South Asia by : Muhammad Asif Hanif

Download or read book Medicinal Plants of South Asia written by Muhammad Asif Hanif and published by Elsevier. This book was released on 2019-09-14 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Plants of South Asia: Novel Sources for Drug Discovery provides a comprehensive review of medicinal plants of this region, highlighting chemical components of high potential and applying the latest technology to reveal the underlying chemistry and active components of traditionally used medicinal plants. Drawing on the vast experience of its expert editors and authors, the book provides a contemporary guide source on these novel chemical structures, thus making it a useful resource for medicinal chemists, phytochemists, pharmaceutical scientists and everyone involved in the use, sales, discovery and development of drugs from natural sources. - Provides comprehensive reviews of 50 medicinal plants and their key properties - Examines the background and botany of each source before going on to discuss underlying phytochemistry and chemical compositions - Links phytochemical properties with pharmacological activities - Supports data with extensive laboratory studies of traditional medicines

Microwave-Induced Synthesis of Aromatic Heterocycles

Download Microwave-Induced Synthesis of Aromatic Heterocycles PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9400714858
Total Pages : 98 pages
Book Rating : 4.4/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Microwave-Induced Synthesis of Aromatic Heterocycles by : Abdul Rauf

Download or read book Microwave-Induced Synthesis of Aromatic Heterocycles written by Abdul Rauf and published by Springer Science & Business Media. This book was released on 2011-09-18 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than a century, heterocycles have played a crucial role in the biological and industrial development of society, becoming one of the most researched areas within organic chemistry. The first chapter of Microwave-Induced Synthesis of Aromatic Heterocycles is based on microwave theory, the latest developments in instrumentation technology, and the various microwave technologies used for synthesis. The remainder of the chapters are divided into two sections. Section A deals with the five-membered heterocycles (pyrazoles, isoxazoles, triazoles, oxadiazoles, thiazoles, imidazoles, oxazoles, oxazolines etc.) and in Section B, various six-membered heterocycles (triazines, benzoxazoles, benzimidazoles, benzothiazoles) are presented. Both sections contain a detailed, recent literature review of microwave assisted synthesis and its applicability to various aromatic heterocyclics.

Organofluorine Compounds in Biology and Medicine

Download Organofluorine Compounds in Biology and Medicine PDF Online Free

Author :
Publisher : Newnes
ISBN 13 : 044453749X
Total Pages : 331 pages
Book Rating : 4.4/5 (445 download)

DOWNLOAD NOW!


Book Synopsis Organofluorine Compounds in Biology and Medicine by : V Prakash Reddy

Download or read book Organofluorine Compounds in Biology and Medicine written by V Prakash Reddy and published by Newnes. This book was released on 2015-01-25 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. - Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds - Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways - Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry

Advances in Heterocyclic Chemistry

Download Advances in Heterocyclic Chemistry PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128048468
Total Pages : 326 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 2016-01-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry is the definitive series in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds. - Considered the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists - Provides the latest comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Fluorine in Heterocyclic Chemistry Volume 1

Download Fluorine in Heterocyclic Chemistry Volume 1 PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319043463
Total Pages : 683 pages
Book Rating : 4.3/5 (19 download)

DOWNLOAD NOW!


Book Synopsis Fluorine in Heterocyclic Chemistry Volume 1 by : Valentine Nenajdenko

Download or read book Fluorine in Heterocyclic Chemistry Volume 1 written by Valentine Nenajdenko and published by Springer. This book was released on 2014-06-30 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.

Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons

Download Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons PDF Online Free

Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.3/5 (121 download)

DOWNLOAD NOW!


Book Synopsis Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Bitumens and Bitumen Emissions, and Some N- and S-heterocyclic Polycyclic Aromatic Hydrocarbons written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2013 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of bitumens and their emissions, the N-heterocyclic polycyclic aromatic hydrocarbons benz[a]acridine, benz[c]acridine, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[c,h]acridine, carbazole and 7H-dibenzo[c,g]carbazole, as well as the S-hetrocyclic polycyclic aromatic hydrocarbons benzo[b]naphtho[2,1-d]thiophene and dibenzothiophene. Bitumens are produced by distillation of crude oil during petroleum refining, and also occur naturally. Bitumens can be divided into six broad classes, according to their physical properties and specifications required for different applications. The major use (about 80%) of bitumens is for road paving; other uses include roofing, waterproofing, sealing and painting. The term "bitumen" should not be confused with "asphalt", which refers to the mixture of bitumen (4-10% by weight), small stones, sand and filler used for road paving. Bitumens are complex mixtures that contain a large number of organic chemical compounds. Application of bitumens may generate emissions (fumes and vapours) that may contain, among volatile and non-volatile compounds, a number of known or probable carcinogens. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of various occupations that entail exposure to bitumens and bitumen emissions, including road paving, roofing, and application of mastic asphalt, and to various heterocyclic polycyclic aromatic compounds.

Advances in Heterocyclic Chemistry

Download Advances in Heterocyclic Chemistry PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0443193150
Total Pages : 296 pages
Book Rating : 4.4/5 (431 download)

DOWNLOAD NOW!


Book Synopsis Advances in Heterocyclic Chemistry by : Eric F.V. Scriven

Download or read book Advances in Heterocyclic Chemistry written by Eric F.V. Scriven and published by Elsevier. This book was released on 2023-02-07 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry, Volume 139, the latest release in this definitive series on the field of heterocyclic chemistry, combines descriptive synthetic chemistry and mechanistic insights to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Topics in this new release include Application of the Fischer indole synthesis in medicinal chemistry, Oxindole Synthesis via C-H Activation Methods, Ring-Closing Metathesis in the Synthesis of Fused Indole Structures, Synthesis of fuller heterocycles, The Literature of Heterocyclic Chemistry, Part XX, 2020, and Heterocyclic Zwitterions Based on Coupled Polymethines. - Presents what is considered to be the definitive serial in the field of heterocyclic chemistry - Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists - Provides the latest comprehensive reviews written by established authorities in the field - Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Bioactive Heterocyclic Compound Classes

Download Bioactive Heterocyclic Compound Classes PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527664475
Total Pages : 367 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!


Book Synopsis Bioactive Heterocyclic Compound Classes by : Clemens Lamberth

Download or read book Bioactive Heterocyclic Compound Classes written by Clemens Lamberth and published by John Wiley & Sons. This book was released on 2012-08-16 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry of heterocycles is an important branch of organic chemistry. This is due to the fact that a large number of natural products, e. g. hormones, antibiotics, vitamins, etc. are composed of heterocyclic structures. Often, these compounds show beneficial properties and are therefore applied as pharmaceuticals to treat diseases or as insecticides, herbicides or fungicides in crop protection. This volume presents important pharmaceuticals. Each of the 20 chapters covers in a concise manner one class of heterocycles, clearly structuredas follows: * Structural formulas of most important examples (market products) * Short background of history or discovery * Typical syntheses of important examples * Mode of action * Characteristic biological activity * Structure-activity relationship * Additional chemistry information (e.g. further transformations, alternative syntheses, metabolic pathways, etc.) * References. A valuable one-stop reference source for researchers in academia and industry as well as for graduate students with career aspirations in the pharmaceutical chemistry.