Hepatitis E Virus

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New Drug Development for Known and Emerging Viruses

Author : Helga Rübsamen-Schaeff
Publisher : John Wiley & Sons
ISBN 13 : 3527810706
Total Pages : 530 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis New Drug Development for Known and Emerging Viruses by : Helga Rübsamen-Schaeff

Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2021-11-30 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the ;pharmaceutical industry and public health agencies.

The Liver

Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis The Liver by : Irwin M. Arias

Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Viral Hepatitis in Children

Author : Mei-Hwei Chang
Publisher : Springer
ISBN 13 : 981130050X
Total Pages : 229 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Viral Hepatitis in Children by : Mei-Hwei Chang

Download or read book Viral Hepatitis in Children written by Mei-Hwei Chang and published by Springer. This book was released on 2019-07-15 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is aimed to emphasize the rationale and importance of prevention and management of viral hepatitis in children, providing cutting edge knowledge. Viral hepatitis is a major health problem in the world. Although most complications of viral hepatitis are observed in adults, primary infection with hepatitis viruses often occurs during infancy or childhood. To better control viral hepatitis, prevention and therapy if possible should be started in childhood. This book offers updated and unique information about viral hepatitis in children, which has vitally important impact on global disease outcome and control, yet not discussed as frequently as viral hepatitis in adults in previous medical literature. Better prevention and management strategies are covered, starting from infancy and childhood, and even earlier during fetal life. It will be very helpful for better control of viral hepatitis both for daily practice and for developing future strategies and directions. If we can successfully control viral hepatitis in children, there will be very little remaining chronic hepatitis and related complications such as liver cirrhosis or hepatoma in adults. We hope readers, including medical students, researchers, pediatricians, family medicine physicians, infectious disease personnel, public health workers, gastroenterologists, hepatologists and parents of children with chronic hepatitis, will be benefited by reading this book.

Hepatitis E Virus

Author : Youchun Wang
Publisher : Springer
ISBN 13 : 9789402414431
Total Pages : 0 pages
Book Rating : 4.4/5 (144 download)

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Book Synopsis Hepatitis E Virus by : Youchun Wang

Download or read book Hepatitis E Virus written by Youchun Wang and published by Springer. This book was released on 2018-07-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systematically and comprehensively discusses the biological, epidemiological and clinical characteristics of the hepatitis E virus (HEV). It presents current knowledge of HEV and explores experimental methods, treatment and prevention of HEV. First identified in the 1980s and cloned in 1990, HEV is the causative agent of Hepatitis E, which mainly occurs in developing regions, such as Southeast Asia, Middle East and Africa, and significantly affects the health of the people in these areas. It is estimated that a third of the world’s population has been infected with HEV, which is transmitted via the fecal-oral route and can infect both human and animals. The book provides an overview of HEV from benchside to bedside. It is a valuable resource for researchers in the field and those in the pharmaceutical industry developing HEV vaccines, as well as physicians involved in identifying and treating those infected with the virus.

Animal-Origin Viral Zoonoses

Author : Yashpal Singh Malik
Publisher : Springer Nature
ISBN 13 : 9811526516
Total Pages : 386 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Animal-Origin Viral Zoonoses by : Yashpal Singh Malik

Download or read book Animal-Origin Viral Zoonoses written by Yashpal Singh Malik and published by Springer Nature. This book was released on 2020-09-23 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second volume in the series Livestock Diseases and Management, and reviews the importance and implications of animal origin viral zoonoses. It also highlights the specific etiology and epidemiology of these viral infections and discusses their various biological and mechanical transmission mechanisms. Further, the book reviews various measures for controlling viral zoonoses and examines novel therapeutic and prophylactic strategies. Discussing recent studies on the pathogenesis and host immune response to these infections, it underscores the importance of using vaccines against these viral diseases to reduce the risk of them being transmitted to humans.Lastly, it describes in detail the challenges posed by these viral infections and our readiness to face them.

Enteric Hepatitis Viruses

Author : Stanley M. Lemon
Publisher : Perspectives Cshl
ISBN 13 : 9781621821625
Total Pages : 400 pages
Book Rating : 4.8/5 (216 download)

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Book Synopsis Enteric Hepatitis Viruses by : Stanley M. Lemon

Download or read book Enteric Hepatitis Viruses written by Stanley M. Lemon and published by Perspectives Cshl. This book was released on 2018 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor Perspectives in Medicine"--title page.

Diseases of Swine

Author : Jeffrey J. Zimmerman
Publisher : John Wiley & Sons
ISBN 13 : 1119350859
Total Pages : 1136 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Diseases of Swine by : Jeffrey J. Zimmerman

Download or read book Diseases of Swine written by Jeffrey J. Zimmerman and published by John Wiley & Sons. This book was released on 2019-06-18 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a fully revised Eleventh Edition of the definitive reference to swine health and disease Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information. Diseases of Swine covers a wide range of essential topics on swine production, health, and management, with contributions from more than 100 of the foremost international experts in the field. This revised edition makes the information easy to find and includes expanded information on welfare and behavior. A key reference for anyone involved in the swine industry, Diseases of Swine, Eleventh Edition: Presents a thorough revision to the gold-standard reference on pig health and disease Features full color images throughout the book Includes information on the most current advances in the field Provides comprehensive information on swine welfare and behavior Offers a reorganized format to make the information more accessible Written for veterinarians, academicians, students, and individuals and agencies responsible for swine health and public health, Diseases of Swine, Eleventh Edition is an essential guide to swine health. "The 11th edition of Diseases of Swine continues to serve as the gold-standard resource for anything and everything related to swine herd health...this edition does an outstanding job of keeping up with the advanced diagnostic technologies and the latest research on new or emerging diseases and syndromes...there is no other informational resource that comes close to providing the depth or quality of information on the topic of swine diseases as does this book"

Fenner and White's Medical Virology

Author : Christopher J. Burrell
Publisher : Academic Press
ISBN 13 : 0123751578
Total Pages : 605 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Fenner and White's Medical Virology by : Christopher J. Burrell

Download or read book Fenner and White's Medical Virology written by Christopher J. Burrell and published by Academic Press. This book was released on 2016-11-09 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors. The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges. These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology. - Features updated and expanded coverage of pathogenesis and immunity - Contains the latest laboratory diagnostic methods - Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control

Hepatitis and Liver Cancer

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309153689
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hepatitis and Liver Cancer by : Institute of Medicine

Download or read book Hepatitis and Liver Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 2010-04-23 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global epidemic of hepatitis B and C is a serious public health problem. Hepatitis B and C are the major causes of chronic liver disease and liver cancer in the world. In the next 10 years, 150,000 people in the United States will die from liver disease or liver cancer associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infections. Today, between 800,000 and 1.4 million people in the United States have chronic hepatitis B and between 2.7 and 3.9 million have chronic hepatitis C. People most at risk for hepatitis B and C often are the least likely to have access to medical services. Reducing the rates of illness and death associated with these diseases will require greater awareness and knowledge among health care workers, improved identification of at-risk people, and improved access to medical care. Hepatitis B is a vaccine-preventable disease. Although federal public health officials recommend that all newborns, children, and at-risk adults receive the vaccine, about 46,000 new acute cases of the HBV infection emerge each year, including 1,000 in infants who acquire the infection during birth from their HBV-positive mothers. Unfortunately, there is no vaccine for hepatitis C, which is transmitted by direct exposure to infectious blood. Hepatitis and Liver Cancer identifies missed opportunities related to the prevention and control of HBV and HCV infections. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. It identifies priorities for research, policy, and action geared toward federal, state, and local public health officials, stakeholder, and advocacy groups and professional organizations.

Neuroepidemiology in Tropical Health

Author : Pierre-Marie Preux
Publisher : Academic Press
ISBN 13 : 0128046252
Total Pages : 342 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroepidemiology in Tropical Health by : Pierre-Marie Preux

Download or read book Neuroepidemiology in Tropical Health written by Pierre-Marie Preux and published by Academic Press. This book was released on 2017-09-21 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroepidemiology in Tropical Health covers major neurological diseases of relevance in tropical settings and examines the specificities of epidemiology of neurological diseases in the context of tropical countries that face many challenges when compared to the developed world. Part One focuses on methods and their eventual specificities, and how such methods, like sampling, can be adapted for specific scenarios. Parts Two and Three discuss environmental factors and their consequences for neurology in the tropical world, as well as large geographical areas and their specificities. Finally, Part Four presents relevant neurological diseases in in-depth chapters. This invaluable information will help readers recognize the various neurological conditions presented, with the inclusion of their aetiologies and treatment in tropical areas. The book therefore fills a gap in the neuroepidemiology literature, with chapters written by an international collection of experienced authors in the field. Highlights differences and similarities between neuroepidemiology in tropical areas and temperate zones with a focus on methods and underlying factors Covers environmental factors in the tropical world and their consequences for neurology Chapters include references (key articles, books, protocols) for additional detailed study Includes wide topics of neurological disease in the tropics, not only infectious diseases, but also nutrition and public health

Infections of the Central Nervous System

Author : Fabrice Chretien
Publisher : John Wiley & Sons
ISBN 13 : 1119467799
Total Pages : 894 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Infections of the Central Nervous System by : Fabrice Chretien

Download or read book Infections of the Central Nervous System written by Fabrice Chretien and published by John Wiley & Sons. This book was released on 2020-01-08 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Der neue Band aus der Reihe International Society of Neuropathology wurde anlässlich der British Medical Association (BMA) Awards 2019 wärmstens empfohlen. Die Herausgeber sind Experten des Fachgebiets und beschreiben Infektionen des Nervensystems mit ihren klinischen, pathologischen und genetischen Eigenheiten. Auch seltene Erkrankungen werden in übersichtlichen Kapiteln erläutert, zusammen mit Definitionen, mikrobiologischen Eigenschaften, Epidemiologie, klinischen Ausprägungen, Labortests, Pathologie, Genetik und Behandlungsoptionen.

Liver Transplantation

Author : James Neuberger
Publisher : John Wiley & Sons
ISBN 13 : 1119633990
Total Pages : 592 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Liver Transplantation by : James Neuberger

Download or read book Liver Transplantation written by James Neuberger and published by John Wiley & Sons. This book was released on 2021-02-25 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore this practical and step-by-step guide to managing liver transplant patients from leading international clinicians in Hepatology The newly revised Second Edition of Liver Transplantation: Clinical Assessment and Management delivers expert clinical guidance on best practices in managing the care of liver transplant patients. Authors are all experts in their field and cover a world-wide perspective. Organized in an accessible, stepwise fashion and packed with text features such as key points, the book covers all critical areas of each stage of the liver transplant journey, from assessment, to management on the list, to long term care. Readers will learn when to refer a patient for liver transplantation, how to assess a potential liver transplant recipient, learn the principles of the procedure and the long term management of the transplant recipient. Liver Transplantation provides the entire hepatology and surgical team the information required for a sound understanding of the entire procedure, from pre- to post-operative care and management. Clinically oriented and management-focused, the book is far more accessible than the liver transplant sections in traditional hepatology textbooks. Readers will also enjoy: A thorough discussion of when to refer a patient for liver transplantation, including general considerations and the use and abuse of prognostic models An exploration of the selection, assessment, and management of patients on the transplant list, including how to manage a patient with chronic liver disease while on the waiting list A treatment of liver transplantation for acute liver failure (ALF), including assessment and management of ALF patients on the transplant waiting list A discussion of care of the liver transplant recipient after the procedure in the short and long term Perfect for gastroenterologists, hepatologists, and surgeons and other health care professionals managing patients with liver disease who are awaiting, undergoing and following liver transplantation, Liver Transplantation: Clinical Assessment and Management will also earn a place in the libraries of medical students, residents, internal medicine physicians, and GI/Hepatology trainees and all health care professionals providing clinical care to people with liver disease, before, during and after transplantation.

Leveraging Data Science for Global Health

Author : Leo Anthony Celi
Publisher : Springer Nature
ISBN 13 : 3030479943
Total Pages : 471 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Leveraging Data Science for Global Health by : Leo Anthony Celi

Download or read book Leveraging Data Science for Global Health written by Leo Anthony Celi and published by Springer Nature. This book was released on 2020-07-31 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources. Developing countries are uniquely prone to large-scale emerging infectious disease outbreaks due to disruption of ecosystems, civil unrest, and poor healthcare infrastructure – and without comprehensive surveillance, delays in outbreak identification, resource deployment, and case management can be catastrophic. In combination with context-informed analytics, students will learn how non-traditional digital disease data sources – including news media, social media, Google Trends, and Google Street View – can fill critical knowledge gaps and help inform on-the-ground decision-making when formal surveillance systems are insufficient.

Emerging and Transboundary Animal Viruses

Author : Yashpal Singh Malik
Publisher : Springer
ISBN 13 : 9789811504013
Total Pages : 377 pages
Book Rating : 4.5/5 (4 download)

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Book Synopsis Emerging and Transboundary Animal Viruses by : Yashpal Singh Malik

Download or read book Emerging and Transboundary Animal Viruses written by Yashpal Singh Malik and published by Springer. This book was released on 2020-03-05 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, which is the first volume of the book series-Livestock Diseases and Management, summarizes the prominence and implications of the emerging and transboundary animal viruses. Although the livestock plays an important role in the economy of many countries, the emerging and transboundary animal viral diseases possess a serious risk to the animal-agriculture sector and food security globally. The book describes the precise and up-to-date information on animal viral diseases which have emerged in the recent past or are re-emerging due to various environmental factors and those which are not bounded in restricted national boundaries and attained the transboundary status. The chapters summarize the recent advancements in the molecular state-of-art tools towards the development of diagnostics, prophylactics, and therapeutics of these viruses. It also explicitly describes the challenges imposed by the emerging and transboundary viral infections and our preparedness to counter them.

Food-borne Viruses

Author : M. P. G. Koopmans
Publisher :
ISBN 13 : 9781628702248
Total Pages : 245 pages
Book Rating : 4.7/5 (22 download)

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Book Synopsis Food-borne Viruses by : M. P. G. Koopmans

Download or read book Food-borne Viruses written by M. P. G. Koopmans and published by . This book was released on 2008 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food-borne viruses are recognized as a major health concern, but their distribution, definition, and impact are poorly understood. The volume Food-Borne Viruses goes a long way in correcting that problem. Written by leading scientists in the field, it brings together the latest knowledge on these viral strains, their detection and control, and associated challenges.

Game Meat Hygiene

Author : Peter Paulsen
Publisher : Brill Wageningen Academic
ISBN 13 : 9789086862955
Total Pages : 0 pages
Book Rating : 4.8/5 (629 download)

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Book Synopsis Game Meat Hygiene by : Peter Paulsen

Download or read book Game Meat Hygiene written by Peter Paulsen and published by Brill Wageningen Academic. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increased consumers ́ demand for game meat is driven by various motivations. In order to fulfil this demand for safe, wholesome and nutritious meat, management of wild game and establishment of adequate supply chains are required. Identification and assessment of hazards of biological and non-biological origin help to design and implement effective control measures. This requires cooperation of the stakeholders, of food safety authorities and scientists. Game meat safety extends from the wildlife-human interface to wildlife-livestock interactions, as regards transfer of pathogenic agents or transfer of residues. Thus, assurance of game meat hygiene is a multidisciplinary task, and involves tackling a variety of safety and quality issues for a number of species under diverse living conditions and modes of harvesting. This is reflected in the contents of this volume, with 19 contributions on free-living or farmed game and on invasive species, namely the warthog in South Africa.This volume is the third in a series on safety and quality assurance along the game meat chain, following a 'from forest to fork' approach. Like its predecessors, it is targeted at scientists in academia and industry, graduate students as well as to governmental officials in veterinary public health and food safety.

Encyclopedia of Virology

Author : Allan Granoff
Publisher : Academic Press
ISBN 13 :
Total Pages : 926 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedia of Virology by : Allan Granoff

Download or read book Encyclopedia of Virology written by Allan Granoff and published by Academic Press. This book was released on 1999-09-03 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reference source of current virological knowledge. It is also the first to bring together all aspects of the subject for a wide variety of readers. Unique in its use of concise 'mini-review' articles, the mate rial covers biological, molecular, and medical topics concerning viruses in animals, plants, bacteria, and insects. More general articles focus on the effects of viruses on the immune system, the role of viruses in disease, oncology, gene therapy, and evolution, plus a wide range of related topics.