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Gpcr Signaling In The Genesis And Progression Of Pancreatic Cancer
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Book Synopsis GPCR Signaling in the Genesis and Progression of Pancreatic Cancer by : Jacob Andrew Gardner
Download or read book GPCR Signaling in the Genesis and Progression of Pancreatic Cancer written by Jacob Andrew Gardner and published by . This book was released on 2009 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis G Protein-coupled Receptor Mediated Signaling Pathways in Human Pancreatic Cancer by : Sushovan Guha
Download or read book G Protein-coupled Receptor Mediated Signaling Pathways in Human Pancreatic Cancer written by Sushovan Guha and published by . This book was released on 2005 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Innovative Medicine by : Kazuwa Nakao
Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Book Synopsis Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression by : Antonella Zannetti
Download or read book Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression written by Antonella Zannetti and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Advances in the Biology, Therapy and Management of Melanoma by : Lester Davids
Download or read book Recent Advances in the Biology, Therapy and Management of Melanoma written by Lester Davids and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.
Book Synopsis Handbook of Cell Signaling by : Ralph A. Bradshaw
Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Contains over 350 chapters of comprehensive coverage on cell signaling Includes discussion on topics from ligand/receptor interactions to organ/organism responses Provides user-friendly, well-illustrated, reputable content by experts in the field
Book Synopsis Transduction Mechanisms in Cellular Signaling by : Edward A. Dennis
Download or read book Transduction Mechanisms in Cellular Signaling written by Edward A. Dennis and published by Academic Press. This book was released on 2011-04-04 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences. Articles written and edited by experts in the field Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease
Book Synopsis Abeloff's Clinical Oncology E-Book by : John E. Niederhuber
Download or read book Abeloff's Clinical Oncology E-Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2019-01-08 with total page 2208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up. Includes new chapters on Cancer Metabolism and Clinical Trial Designs in Oncology and a standalone chapter on lifestyles and cancer prevention. Features extensive updates including the latest clinical practice guidelines, decision-making algorithms, and clinical trial implications, as well as new content on precision medicine, genetics, and PET/CT imaging. Includes revised diagnostic and treatment protocols for medical management, surgical considerations, and radiation oncology therapies, stressing a multispecialty, integrated approach to care. Helps you find information quickly with updated indexing related to management recommendations, focused fact summaries, updated key points at the beginning of each chapter ideal for quick reference and board review, and algorithms for patient evaluation, diagnosis, and treatment options. Offers more patient care coverage in disease chapters, plus new information on cancer as a chronic illness and cancer survivorship. Discusses today’s key topics such as immuno-oncology, functional imaging, precision medicine, the application of genetics in pathologic diagnosis and sub-categorization of tumors as well as the association of chronic infectious diseases such as HIV and cancer.
Book Synopsis From Melanocytes to Melanoma by : Vincent J. Hearing
Download or read book From Melanocytes to Melanoma written by Vincent J. Hearing and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.
Book Synopsis Lentiviral Vectors by : Didier Trono
Download or read book Lentiviral Vectors written by Didier Trono and published by Springer Science & Business Media. This book was released on 2001-12-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time a compilation of chapters that depict the biological bases underlying the development of lentiviral vectors, the techniques involved in the manufacture of this new gene delivery tool, and its most promising applications.
Book Synopsis Signaling Pathways in Cancer Pathogenesis and Therapy by : David A. Frank
Download or read book Signaling Pathways in Cancer Pathogenesis and Therapy written by David A. Frank and published by Springer Science & Business Media. This book was released on 2011-11-12 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.
Book Synopsis Cellular Endocrinology in Health and Disease by : Alfredo Ulloa-Aguirre
Download or read book Cellular Endocrinology in Health and Disease written by Alfredo Ulloa-Aguirre and published by Academic Press. This book was released on 2021-02-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field
Book Synopsis Cancer Signaling by : Christoph Wagener
Download or read book Cancer Signaling written by Christoph Wagener and published by John Wiley & Sons. This book was released on 2016-08-12 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Book Synopsis Free Fatty Acid Receptors by : Graeme Milligan
Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Book Synopsis Zinc Signaling by : Toshiyuki Fukada
Download or read book Zinc Signaling written by Toshiyuki Fukada and published by Springer Nature. This book was released on 2019-12-13 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.
Book Synopsis History of the Pancreas: Mysteries of a Hidden Organ by : John M. Howard
Download or read book History of the Pancreas: Mysteries of a Hidden Organ written by John M. Howard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: Never before has a comprehensive history of the pancreas like History of the Pancreas been published. It not only is a historical review of the science of medicine, it is liberally interspersed with anecdotal vignettes of the researchers who have worked on this organ. Much of it, such as the discovery of the duct of Wirsüng, of the islets of Langerhans, of insulin, gastrin and their tumors, reads like the adverture, which it is. This book, divided into 14 chapters, is written in a narrative style and is easily readable, as glimpses of the investigators, those who failed as well as those who succeeded, adds both perspective and human interest. Each chapter is completely referenced, totaling over 1500 references. As a reference book for students, teachers, investigators, writers, its detailed hjistorical documentation is unique. From the pre-Christian era of Asia Minor, to Greece, Rome, Europe and America, to the explosive progress in Japan, the history is there. History of the Pancreas: Mysteries of a Hidden Organ fills a gap.
Book Synopsis Physics of Cancer by : Claudia Mierke
Download or read book Physics of Cancer written by Claudia Mierke and published by Iph001. This book was released on 2018-10-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.