Governing Protecting And Regulating The Future Of Genome Editing

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Governing, Protecting, and Regulating the Future of Genome Editing

Author : Santa Slokenberga
Publisher : BRILL
ISBN 13 : 9004526137
Total Pages : 319 pages
Book Rating : 4.0/5 (45 download)

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Book Synopsis Governing, Protecting, and Regulating the Future of Genome Editing by : Santa Slokenberga

Download or read book Governing, Protecting, and Regulating the Future of Genome Editing written by Santa Slokenberga and published by BRILL. This book was released on 2023-03-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited collection examines the ethical, legal, social and policy implications of genome editing technologies. Moreover, it offers a broad spectrum of timely legal analysis related to bringing genome editing to the market and making it available to patients, including addressing genome editing technology regulation through procedures for regulatory approval, patent law and competition law. In twelve chapters, this volume offers persuasive arguments for justifying transformative regulatory interventions regarding human genome editing, as well as the various legal venues for introducing necessary or desirable changes needed to create an environment for realizing the potential of genome editing technology for the benefit of patients and society.

Human Genome Editing

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452880
Total Pages : 329 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Human Genome Editing by : National Academies of Sciences, Engineering, and Medicine

Download or read book Human Genome Editing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-08-13 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Regulation and Governance of Gene Editing Technologies (CRISPR, etc.)

Author : Alberto Asquer
Publisher : Frontiers Media SA
ISBN 13 : 2832503918
Total Pages : 113 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Regulation and Governance of Gene Editing Technologies (CRISPR, etc.) by : Alberto Asquer

Download or read book Regulation and Governance of Gene Editing Technologies (CRISPR, etc.) written by Alberto Asquer and published by Frontiers Media SA. This book was released on 2022-11-04 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heritable Human Genome Editing

Author : The Royal Society
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Human Germline Modification and the Right to Science

Author : Andrea Boggio
Publisher : Cambridge University Press
ISBN 13 : 1108499872
Total Pages : 681 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Human Germline Modification and the Right to Science by : Andrea Boggio

Download or read book Human Germline Modification and the Right to Science written by Andrea Boggio and published by Cambridge University Press. This book was released on 2020-01-09 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Rewriting Nature

Author : Paul Enríquez
Publisher : Cambridge University Press
ISBN 13 : 1108613624
Total Pages : 441 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Rewriting Nature by : Paul Enríquez

Download or read book Rewriting Nature written by Paul Enríquez and published by Cambridge University Press. This book was released on 2021-06-24 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: History will mark the twenty-first century as the dawn of the age of precise genetic manipulation. Breakthroughs in genome editing are poised to enable humankind to fundamentally transform life on Earth. Those familiar with genome editing understand its potential to revolutionize civilization in ways that surpass the impact of the discovery of electricity and the development of gunpowder, the atomic bomb, or the Internet. Significant questions regarding how society should promote or hinder genome editing loom large in the horizon. And it is up to humans to decide the fate of this powerful technology. Rewriting Nature is a compelling, thought-provoking interdisciplinary exploration of the law, science, and policy of genome editing. The book guides readers through complex legal, scientific, ethical, political, economic, and social issues concerning this emerging technology, and challenges the conventional false dichotomy often associated with science and law, which contributes to a growing divide between both fields.

Genetically Engineered Crops

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309437385
Total Pages : 607 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Genetically Engineered Crops by : National Academies of Sciences, Engineering, and Medicine

Download or read book Genetically Engineered Crops written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-01-28 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

Plant Genome Editing – Policies and Governance

Author : Thorben Sprink
Publisher : Frontiers Media SA
ISBN 13 : 2889636704
Total Pages : 252 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Plant Genome Editing – Policies and Governance by : Thorben Sprink

Download or read book Plant Genome Editing – Policies and Governance written by Thorben Sprink and published by Frontiers Media SA. This book was released on 2020-04-22 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

CRISPR and RNAi Systems

Author : Kamel A Abd-Elsalam
Publisher : Elsevier
ISBN 13 : 0128219114
Total Pages : 842 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis CRISPR and RNAi Systems by : Kamel A Abd-Elsalam

Download or read book CRISPR and RNAi Systems written by Kamel A Abd-Elsalam and published by Elsevier. This book was released on 2021-02-27 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are vulnerable to pathogens including fungi, bacteria, and viruses, which cause critical problems and deficits. Crop protection by plant breeding delivers a promising solution with no obvious effect on human health or the local ecosystem. Crop improvement has been the most powerful approach for producing unique crop cultivars since domestication occurred, making possible the main innovations in feeding the globe and community development. Genome editing is one of the genetic devices that can be implemented, and disease resistance is frequently cited as the most encouraging application of CRISPR/Cas9 technology in agriculture. Nanobiotechnology has harnessed the power of genome editing to develop agricultural crops. Nanosized DNA or RNA nanotechnology approaches could contribute to raising the stability and performance of CRISPR guide RNAs. This book brings together the latest research in these areas. CRISPR and RNAi Systems: Nanobiotechnology Approaches to Plant Breeding and Protection presents a complete understanding of the RNAi and CRISPR/Cas9 techniques for controlling mycotoxins, fighting plant nematodes, and detecting plant pathogens. CRISPR/Cas genome editing enables efficient targeted modification in most crops, thus promising to accelerate crop improvement. CRISPR/Cas9 can be used for management of plant insects, and various plant pathogens. The book is an important reference source for both plant scientists and environmental scientists who want to understand how nano biotechnologically based approaches are being used to create more efficient plant protection and plant breeding systems. Shows how nanotechnology is being used as the basis for new solutions for more efficient plant breeding and plant protection Outlines the major techniques and applications of both CRISPR and RNAi technologies Assesses the major challenges of escalating these technologies on a mass scale

Preparing for Future Products of Biotechnology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452058
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Preparing for Future Products of Biotechnology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preparing for Future Products of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.

Regulation of Genome Editing in Plant Biotechnology

Author : Hans-Georg Dederer
Publisher : Springer
ISBN 13 : 3030171191
Total Pages : 372 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Regulation of Genome Editing in Plant Biotechnology by : Hans-Georg Dederer

Download or read book Regulation of Genome Editing in Plant Biotechnology written by Hans-Georg Dederer and published by Springer. This book was released on 2019-08-16 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth insights into the regulatory frameworks of five countries and the EU concerning the regulation of genome edited plants. The country reports form the basis for a comparative analysis of the various national regulations governing genetically modified organisms (GMOs) in general and genome edited plants in particular, as well as the underlying regulatory approaches.The reports, which focus on the regulatory status quo of genome edited plants in Argentina, Australia, Canada, the EU, Japan and the USA, were written by distinguished experts following a uniform structure. On this basis, the legal frameworks are compared in order to foster a rational assessment of which approaches could be drawn upon to adjust, or to completely realign, the current EU regime for GMOs. In addition, a separate chapter identifies potential best practices for the regulation of plants derived from genome editing.

Science in a Democratic Society

Author : Philip Kitcher
Publisher : Prometheus Books
ISBN 13 : 1616144084
Total Pages : 326 pages
Book Rating : 4.6/5 (161 download)

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Book Synopsis Science in a Democratic Society by : Philip Kitcher

Download or read book Science in a Democratic Society written by Philip Kitcher and published by Prometheus Books. This book was released on 2011-09-20 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this successor to his pioneering Science, Truth, and Democracy, the author revisits the topic explored in his previous work—namely, the challenges of integrating science, the most successful knowledge-generating system of all time, with the problems of democracy. But in this new work, the author goes far beyond that earlier book in studying places at which the practice of science fails to answer social needs. He considers a variety of examples of pressing concern, ranging from climate change to religiously inspired constraints on biomedical research to the neglect of diseases that kill millions of children annually, analyzing the sources of trouble. He shows the fallacies of thinking that democracy always requires public debate of issues most people cannot comprehend, and argues that properly constituted expertise is essential to genuine democracy. No previous book has treated the place of science in democratic society so comprehensively and systematically, with attention to different aspects of science and to pressing problems of our times.

Ethics Dumping

Author : Doris Schroeder
Publisher : Springer
ISBN 13 : 3319647318
Total Pages : 134 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Ethics Dumping by : Doris Schroeder

Download or read book Ethics Dumping written by Doris Schroeder and published by Springer. This book was released on 2017-12-04 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.

Editing Humanity

Author : Kevin Davies
Publisher : Simon and Schuster
ISBN 13 : 1643133942
Total Pages : 402 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis Editing Humanity by : Kevin Davies

Download or read book Editing Humanity written by Kevin Davies and published by Simon and Schuster. This book was released on 2020-10-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.

Genome Edited Plants

Author : Shiv Sanjeevi Sripathi
Publisher : Delve Publishing
ISBN 13 : 9781774691618
Total Pages : pages
Book Rating : 4.6/5 (916 download)

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Book Synopsis Genome Edited Plants by : Shiv Sanjeevi Sripathi

Download or read book Genome Edited Plants written by Shiv Sanjeevi Sripathi and published by Delve Publishing. This book was released on 2021-12 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of domesticating plants dates back to ancient times with initial dependence on natural changes and later approaches using mutagenesis. In order to address the issue of food insecurity due to population demands, decrease in arable land (due to excessive human interference) and climate change, the concept of "gene editing" is being pursued among the slew of approaches by researchers. This book comes at a time given that the year 2020 was ten years since the use of homing endonucleases and zinc finger nucleases to produce the first gene-edited plants. The year 2012 saw the emergence of CRISPR/Cas9, which subsequently altered the arena of gene editing to receive "The Nobel Prize in Chemistry, 2020." The book concisely summarizes the concept of genome editing and its relevance in plants along with the approach, as described by research. Latest developments in approaches along with case studies and examples of genome editing have been elucidated. Further, the current scenario of the regulatory checklists across several countries concerning genome-edited plants has also been presented to enable a reader to gain a complete picture.

Acting in an Uncertain World

Author : Michel Callon
Publisher : MIT Press
ISBN 13 : 0262515962
Total Pages : 301 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Acting in an Uncertain World by : Michel Callon

Download or read book Acting in an Uncertain World written by Michel Callon and published by MIT Press. This book was released on 2011-01-21 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: A call for a new form of democracy in which “hybrid forums” composed of experts and laypeople address such sociotechnical controversies as hazardous waste, genetically modified organisms, and nanotechnology. Controversies over such issues as nuclear waste, genetically modified organisms, asbestos, tobacco, gene therapy, avian flu, and cell phone towers arise almost daily as rapid scientific and technological advances create uncertainty and bring about unforeseen concerns. The authors of Acting in an Uncertain World argue that political institutions must be expanded and improved to manage these controversies, to transform them into productive conversations, and to bring about “technical democracy.” They show how “hybrid forums”—in which experts, non-experts, ordinary citizens, and politicians come together—reveal the limits of traditional delegative democracies, in which decisions are made by quasi-professional politicians and techno-scientific information is the domain of specialists in laboratories. The division between professionals and laypeople, the authors claim, is simply outmoded. The authors argue that laboratory research should be complemented by everyday experimentation pursued in the real world, and they describe various modes of cooperation between the two. They explore a range of concrete examples of hybrid forums that have dealt with sociotechnical controversies including nuclear waste disposal in France, industrial waste and birth defects in Japan, a childhood leukemia cluster in Woburn, Massachusetts, and mad cow disease in the United Kingdom. The authors discuss the implications for political decision making in general and describe a “dialogic” democracy that enriches traditional representative democracy. To invent new procedures for consultation and representation, they suggest, is to contribute to an endless process that is necessary for the ongoing democratization of democracy.

CRISPR People

Author : Henry T. Greely
Publisher : MIT Press
ISBN 13 : 0262543885
Total Pages : 395 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis CRISPR People by : Henry T. Greely

Download or read book CRISPR People written by Henry T. Greely and published by MIT Press. This book was released on 2022-03-01 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us? In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention. The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next. Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.