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Ghrelin In Health And Disease
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Book Synopsis Ghrelin in Health and Disease by : Roy G. Smith
Download or read book Ghrelin in Health and Disease written by Roy G. Smith and published by Springer Science & Business Media. This book was released on 2012-07-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, the editors provide a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Hence, there is a need to combine information from basic translational research on ghrelin with results of clinical investigations. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Book Synopsis Ghrelin: Function, Mechanism of Action and Role in Health and Disease by : Dennis Hertz
Download or read book Ghrelin: Function, Mechanism of Action and Role in Health and Disease written by Dennis Hertz and published by . This book was released on 2020-03-30 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin is a 28-amino acid peptide mainly secreted by the stomach. To better understand the role of ghrelin signaling, Ghrelin: Function, Mechanism of Action and Role in Health and Disease first explores the regulation of age-associated adipose tissue inflammation. Following this, the authors discuss the influence of different variables on the response of short-term appetite regulation induced by exercise. External factors such as temperature and environment exert effects on hormonal responses, including hunger sensation and energy intake. The effects of gender differences and aging on psychological stress-dependent eating disorders are assessed, and the involvement of endogenous ghrelin, the serotonin 2c receptor and the estrogen alpha receptor is discussed. The penultimate chapter reviews the relationship between sleep and eating behavior, focusing in the influences of circadian changes on appetite related responses such as plasma concentration of ghrelin. The concluding study highlights the ghrelin system as a promising candidate for cardiovascular drug discovery, a new therapeutic approach for the treatment of endothelial impairment, and a possible contribution to the prevention of atherosclerosis.
Download or read book The Ghrelin System written by A. Benso and published by Karger Medical and Scientific Publishers. This book was released on 2013-04-22 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ghrelin story started more than 30 years ago with the discovery of synthetic GH secretagogues. Only in 1999 was ghrelin a natural GH-releasing peptide, discovered. Ghrelin, however, is much more than simply a natural GH secretagogue. In fact, this hormone is one of the most important factors known for regulating appetite and energy expenditure. Furthermore, ghrelin is the trigger for other neuroendocrine, metabolic and nonendocrine actions.This book, written by researchers who provided the major contributions to our current knowledge of this complex system, gives a comprehensive overview of the recent advances in ghrelin research. The hormone's influence on the cardiovascular, metabolic and gastroenteropancreatic system, hypothalamus-pituitary-adrenal axis, prolactin secretion, thyroid axis, gonadal axis as well as on behavior is discussed in detail. Furthermore, the clinical perspectives for ghrelin-derived therapeutic products are presented.Illustrating the tight inter-relationship between endocrinology, metabolism, cardiovascular disease and internal medicine, this book is essential reading for all scientists interested in appetite control, body weight and energy expenditure, as well as diabetes mellitus and neuroendocrinology.
Book Synopsis Global Perspectives on Childhood Obesity by : Debasis Bagchi
Download or read book Global Perspectives on Childhood Obesity written by Debasis Bagchi and published by Academic Press. This book was released on 2010-10-12 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the complex factors contributing to the growing childhood obesity epidemic is vital not only for the improved health of the world's future generations, but for the healthcare system. The impact of childhood obesity reaches beyond the individual family and into the public arenas of social systems and government policy and programs. Global Perspectives on Childhood Obesity explores these with an approach that considers the current state of childhood obesity around the world as well as future projections, the most highly cited factors contributing to childhood obesity, what it means for the future both for children and society, and suggestions for steps to address and potentially prevent childhood obesity. This book will cover the multi-faceted factors contributing to the rapidly growing childhood obesity epidemic The underlying causes and current status of rapidly growing obesity epidemic in children in the global scenario will be discussed The strategies for childhood obesity prevention and treatment such as physical activity and exercise, personalized nutrition plans and school and community involvement will be presented
Download or read book Ghrelin written by Ezio Ghigo and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin is a 28-amino acid acylated peptide predominatntly produced by the stomach. Highlights the impact and function of the hormone ghrelin and provides insight to neuroendocrinologies and researchers interested in its molecular and clinical relevance.
Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin
Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.
Book Synopsis Ghrelin in Health and Disease by : Roy G. Smith
Download or read book Ghrelin in Health and Disease written by Roy G. Smith and published by Springer Science & Business Media. This book was released on 2012-10-19 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Book Synopsis Handbook of Hormones by : Yoshio Takei
Download or read book Handbook of Hormones written by Yoshio Takei and published by Academic Press. This book was released on 2015-08-26 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research collates fundamental information about the structure and function of hormones from basic biology to clinical use. The handbook offers a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors and signalling pathways, and the biological activities they regulate. The evolution of hormones and gene families is also covered both in the text and in online ancillaries. Users will find simple and visual ways to learn key molecular information. Chapters and online ancillary resources integrate additional sections, providing a comparative molecular, functional, and evolutionary consideration. Provides the only single resource available with concise, yet informative descriptions of hormones in vertebrates, invertebrates, and plants Presents hormones in groups according to their origin, so that readers can easily understand their inter-relation Includes comparative information on the structures and functions of hormones enabling readers to understand both general and specific actions in and across species Ancillary website hosts additional information, including sequence data, comparative data, figures, and tables
Book Synopsis Clinical Neuroendocrinology by : Michael Wilkinson
Download or read book Clinical Neuroendocrinology written by Michael Wilkinson and published by Cambridge University Press. This book was released on 2019-01-03 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
Book Synopsis Integrative Review of Ghrelin Family Peptides, Musculoskeletal Health and Osteoporotic Fractures by : Leon Fisher
Download or read book Integrative Review of Ghrelin Family Peptides, Musculoskeletal Health and Osteoporotic Fractures written by Leon Fisher and published by Cambridge Scholars Publishing. This book was released on 2024-04-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes multiple effects of four stomach derived hormones (acylated and unacylated ghrelin, obestatin and nesfatin-1) collectively known as ghrelin family peptides (GFPs). The first part of the book focuses on known actions of GFPs under normal physiological conditions. Subsequent chapters describe the role of dysregulation in the production and action of these peptides in the complex network involved in numerous chronic diseases, musculoskeletal health, osteoporosis, falls and, consequently, osteoporotic fractures. The emerging data on the potential diagnostic and therapeutic benefits of GFPs in different disorders and implications on clinical practice is presented, and an extensive bibliography is provided.
Book Synopsis The Belly Fat Fix by : Marjorie Nolan Cohn
Download or read book The Belly Fat Fix written by Marjorie Nolan Cohn and published by Rodale Books. This book was released on 2015-07-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever wonder why you can skip meals and cut calories--but never see the scale budge? Or why you keep craving those rich foods that sabotage weight loss? It's easy to blame yourself for a lack of willpower. But the truth is, you can't lose weight and keep it off without balancing your master hunger hormone--ghrelin. Ghrelin is the hormone that tells your body to eat when you're hungry. The right level of ghrelin keeps you feeling satisfied, slim, and healthy. But stress, lack of sleep, or eating at the wrong times can throw off your ghrelin levels, slowing down your metabolism and packing on belly fat and excess pounds. The good news: It's easy to get your ghrelin cycle back on track and shed that belly fat for good. The Belly Fat Fix shows you how to incorporate the science of ghrelin into an easy plan: • A simple diet packed with anti-ghrelin superfoods. More than 50 easy, delicious, ghrelin-busting recipes. • A quick exercise plan to tone you up and help keep ghrelin at bay. Reset your hunger hormone, fire up your metabolism, and lose that extra weight--up to 15 pounds in 30 days--without ever feeling hungry!
Book Synopsis Fat Detection by : Jean-Pierre Montmayeur
Download or read book Fat Detection written by Jean-Pierre Montmayeur and published by CRC Press. This book was released on 2009-09-14 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se
Book Synopsis The Leptin Diet by : Byron J. Richards
Download or read book The Leptin Diet written by Byron J. Richards and published by Truth in Wellness Llc. This book was released on 2006 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to eat in harmony with the fat hormone leptin and take charge of your health.
Download or read book Fat Planet written by David Lewis and published by Random House. This book was released on 2015-04-09 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our planet is in the grip of an obesity pandemic. More than a billion people worldwide are overweight and over 600 million are obese. We live in an obesogenic environment in which it is much easier to get fat than to stay fit. How has this come to be? Who is to blame? What can we do? In Fat Planet, Dr David Lewis and Dr Margaret Leitch examine the social and psychological causes of the obesity pandemic in order to answer these questions. They use ground-breaking research to highlight the behaviour of corporations that relentlessly promote foods high in sugar, fat and salt, and show that these ‘junk’ foods have shockingly similar neurological effects to hard drugs. They consider the prevalence of food cues which unconsciously stimulate our desire to consume. And they debunk the myths of fad diets and slimming pills, suggesting practical, easily implemented strategies for sustainable weight loss. The evidence is clear: our problem with obesity must be addressed or we will face catastrophic consequences. It is not too late to change.
Book Synopsis Neural Regulation of Metabolism by : Qi Wu
Download or read book Neural Regulation of Metabolism written by Qi Wu and published by Springer. This book was released on 2018-11-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
Book Synopsis Growth Hormone in Health and Disease by :
Download or read book Growth Hormone in Health and Disease written by and published by Academic Press. This book was released on 2016-02-03 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Molecular Biology and Translational Science focuses on the growth hormone in health and disease. Contributions from leading authorities Informs and updates on all the latest developments in the field
Book Synopsis The Secret Life of Fat: The Science Behind the Body's Least Understood Organ and What It Means for You by : Sylvia Tara
Download or read book The Secret Life of Fat: The Science Behind the Body's Least Understood Organ and What It Means for You written by Sylvia Tara and published by W. W. Norton & Company. This book was released on 2016-12-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biochemist shows how we can finally control our fat—by understanding how it works. Fat is not just excess weight, but actually a dynamic, smart, and self-sustaining organ that influences everything from aging and immunity to mood and fertility. With cutting-edge research and riveting case studies—including the story of a girl who had no fat, and that of a young woman who couldn’t stop eating—Dr. Sylvia Tara reveals the surprising science behind our most misunderstood body part and its incredible ability to defend itself. Exploring the unexpected ways viruses, hormones, sleep, and genetics impact fat, Tara uncovers the true secret to losing weight: working with your fat, not against it.
