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Gfp Whole Cell Microbial Biosensors
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Book Synopsis GFP Whole Cell Microbial Biosensors by : Frank Delvigne
Download or read book GFP Whole Cell Microbial Biosensors written by Frank Delvigne and published by Momentum Press. This book was released on 2013-01-09 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two strategies are usually considered for the optimization of microbial bioprocesses. The first one involves genetic or metabolic engineering of the target microbial strains in order to improve its production efficiency or its tolerance to adverse conditions. The second one is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This work is more particularly dedicated to this second class of parameters. Recent developments in bioreactor technologies follow the scaling-out principle, i.e. carrying out several cultures in parallel with controlled conditions for screening purposes. Several mini-bioreactor concepts, i.e. bioreactor with working volume of 1 to 100 mL with controlling devices, have been developed following this principle. In general, chemical engineering similarities between conventional stirred bioreactors and their miniature equivalent are well characterized. However, the actual scaling-up rules are not able to cope with the complexity of the microbial stress response. Indeed, microbial stress response still remains not completely understood considering the process perturbations and the environmental fluctuations accompanying the scaling-up to industrial bioreactors. At this time, this kind of response can only be experimentally predicted by using scale-down bioreactors, i.e. lab-scale bioreactors designed in order to reproduce mixing imperfections that have to be expected at large-scale. However, the use of such an approach is time consuming and requires an experimented staff to elaborate the scaling-down protocols. Indeed, bioprocess development involves several steps which cannot be necessarily linked with each other considering the different cultivation equipment used.
Book Synopsis Handbook of Cell Biosensors by : Gérald Thouand
Download or read book Handbook of Cell Biosensors written by Gérald Thouand and published by Springer. This book was released on 2021-10-01 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is an interdisciplinary and comprehensive reference covering all aspects of cell biosensors. It is divided into four main sections which are led and organized by numerous international experts. The scope of coverage includes: Fundamentals and genetics for biosensor applications Transducers, Materials and Systems Markets, innovation and education Application of biosensors in business Biosensor research is an exciting hybrid world where biologists, chemists, physicists, engineers and computer engineers come together. This handbook will serve as an invaluable living resource for all researchers in academia and industry working with cell biosensors.
Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Book Synopsis Statistical Methods in Analytical Chemistry by : Peter C. Meier
Download or read book Statistical Methods in Analytical Chemistry written by Peter C. Meier and published by John Wiley & Sons. This book was released on 2005-03-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of a successful, bestselling book continues to provide you with practical information on the use of statistical methods for solving real-world problems in complex industrial environments. Complete with examples from the chemical and pharmaceutical laboratory and manufacturing areas, this thoroughly updated book clearly demonstrates how to obtain reliable results by choosing the most appropriate experimental design and data evaluation methods. Unlike other books on the subject, Statistical Methods in Analytical Chemistry, Second Edition presents and solves problems in the context of a comprehensive decision-making process under GMP rules: Would you recommend the destruction of a $100,000 batch of product if one of four repeat determinations barely fails the specification limit? How would you prevent this from happening in the first place? Are you sure the calculator you are using is telling the truth? To help you control these situations, the new edition: * Covers univariate, bivariate, and multivariate data * Features case studies from the pharmaceutical and chemical industries demonstrating typical problems analysts encounter and the techniques used to solve them * Offers information on ancillary techniques, including a short introduction to optimization, exploratory data analysis, smoothing and computer simulation, and recapitulation of error propagation * Boasts numerous Excel files and compiled Visual Basic programs-no statistical table lookups required! * Uses Monte Carlo simulation to illustrate the variability inherent in statistically indistinguishable data sets Statistical Methods in Analytical Chemistry, Second Edition is an excellent, one-of-a-kind resource for laboratory scientists and engineers and project managers who need to assess data reliability; QC staff, regulators, and customers who want to frame realistic requirements and specifications; as well as educators looking for real-life experiments and advanced students in chemistry and pharmaceutical science. From the reviews of Statistical Methods in Analytical Chemistry, First Edition: "This book is extremely valuable. The authors supply many very useful programs along with their source code. Thus, the user can check the authenticity of the result and gain a greater understanding of the algorithm from the code. It should be on the bookshelf of every analytical chemist."-Applied Spectroscopy "The authors have compiled an interesting collection of data to illustrate the application of statistical methods . . . including calibrating, setting detection limits, analyzing ANOVA data, analyzing stability data, and determining the influence of error propagation."-Clinical Chemistry "The examples are taken from a chemical/pharmaceutical environment, but serve as convenient vehicles for the discussion of when to use which test, and how to make sense out of the results. While practical use of statistics is the major concern, it is put into perspective, and the reader is urged to use plausibility checks."-Journal of Chemical Education "The discussion of univariate statistical tests is one of the more thorough I have seen in this type of book . . . The treatment of linear regression is also thorough, and a complete set of equations for uncertainty in the results is presented . . . The bibliography is extensive and will serve as a valuable resource for those seeking more information on virtually any topic covered in the book."-Journal of American Chemical Society "This book treats the application of statistics to analytical chemistry in a very practical manner. [It] integrates PC computing power, testing programs, and analytical know-how in the context of good manufacturing practice/good laboratory practice (GMP/GLP) . . .The book is of value in many fields of analytical chemistry and should be available in all relevant libraries."-Chemometrics and Intelligent Laboratory Systems
Book Synopsis Bacterial Sensors by : Jan Roelof van der Meer
Download or read book Bacterial Sensors written by Jan Roelof van der Meer and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial reporters are live, genetically engineered cells with promising application in bioanalytics. They contain genetic circuitry to produce a cellular sensing element, which detects the target compound and relays the detection to specific synthesis of so-called reporter proteins (the presence or activity of which is easy to quantify). Bioassays with bacterial reporters are a useful complement to chemical analytics because they measure biological responses rather than total chemical concentrations. Simple bacterial reporter assays may also replace more costly chemical methods as a first line sample analysis technique. Recent promising developments integrate bacterial reporter cells with microsystems to produce bacterial biosensors. This lecture presents an in-depth treatment of the synthetic biological design principles of bacterial reporters, the engineering of which started as simple recombinant DNA puzzles, but has now become a more rational approach of choosing and combining sensing, controlling and reporting DNA 'parts'. Several examples of existing bacterial reporter designs and their genetic circuitry will be illustrated. Besides the design principles, the lecture also focuses on the application principles of bacterial reporter assays. A variety of assay formats will be illustrated, and principles of quantification will be dealt with. In addition to this discussion, substantial reference material is supplied in various Annexes. Table of Contents: Short History of the use of Bacteria for Biosensing and Bioreporting / Genetic Engineering Concepts / Measuring with Bioreporters / Epilogue
Book Synopsis Cell-based Biosensors by : Qingjun Liu
Download or read book Cell-based Biosensors written by Qingjun Liu and published by Artech House. This book was released on 2009-10 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by recognized experts the field, this leading-edge resource is the first book to systematically introduce the concept, technology, and development of cell-based biosensors. You find details on the latest cell-based biosensor models and novel micro-structure biosensor techniques. Taking an interdisciplinary approach, this unique volume presents the latest innovative applications of cell-based biosensors in a variety of biomedical fields. The book also explores future trends of cell-based biosensors, including integrated chips, nanotechnology and microfluidics. Over 140 illustrations help clarify key topics throughout the book.
Download or read book Biosensors written by Pier Andrea Serra and published by BoD – Books on Demand. This book was released on 2011-07-18 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biosensor is a detecting device that combines a transducer with a biologically sensitive and selective component. Biosensors can measure compounds present in the environment, chemical processes, food and human body at low cost if compared with traditional analytical techniques. This book covers a wide range of aspects and issues related to biosensor technology, bringing together researchers from 19 different countries. The book consists of 27 chapters written by 106 authors and divided in three sections: Biosensors Technology and Materials, Biosensors for Health and Biosensors for Environment and Biosecurity.
Book Synopsis State of the Art in Biosensors by : Toonika Rinken
Download or read book State of the Art in Biosensors written by Toonika Rinken and published by BoD – Books on Demand. This book was released on 2013-03-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: As biosensors comprise a prospective alternative to traditional chemical analyses, enabling fast on- and in-line measurements with sufficient selectivity, the field is expanding rapidly and is offering new ideas and developments every day. This book aims to cover the present state of the art in the biosensor technology and introduce the general aspects of biosensor- based techniques and methods. The book consists of 13 chapters by 44 authors and is divided into 3 sections, focused on bio-recognition techniques, signal transduction methods and signal analysis.
Book Synopsis Biosensors for Environmental Monitoring by : Toonika Rinken
Download or read book Biosensors for Environmental Monitoring written by Toonika Rinken and published by BoD – Books on Demand. This book was released on 2019-11-20 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Real-time and reliable detection of molecular compounds and bacteria is essential in modern environmental monitoring. For rapid analyses, biosensing devices combining high selectivity of biomolecular recognition and sensitivity of modern signal-detection technologies offer a promising platform. Biosensors allow rapid on-site detection of pollutants and provide potential for better understanding of the environmental processes, including the fate and transport of contaminants.This book, including 12 chapters from 37 authors, introduces different biosensor-based technologies applied for environmental analyses.
Book Synopsis Whole Cell Sensing Systems I by : Shimshon Belkin
Download or read book Whole Cell Sensing Systems I written by Shimshon Belkin and published by Springer. This book was released on 2010-07-13 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of Contents Reporter cells: - Yeast Based Sensors by Mifumi Shimomura-Shimizu and Isao Karube - Mammalian Cell-Based Sensor Systems by Pratik Banerjee, Briana Franz, and Arun K. Bhunia - Fluorescent and Bioluminescent Cell-Based Sensors: Strategies for Their Preservation by Amol Date, Patrizia Pasini, and Sylvia Daunert - Electrochemical Cell-Based Sensors by Eliora Z. Ron and Judith Rishpon - Microbial Cell Arrays by Tal Elad, Jin Hyung Lee, Man Bock Gu, and Shimshon Belkin Devices: - Surface Functionalization for Protein and Cell Patterning by Pascal Colpo , Ana Ruiz , Laura Ceriotti , and François Rossi - Fiber-Optic Based Cell Sensors by Evgeni Eltzov and Robert S. Marks - Electronic Interfacing with Living Cells by James T. Fleming - On-Chip Detection of Cellular Activity by R. Almog , R. Daniel , S. Vernick , A. Ron , H. Ben-Yoav, and Y. Shacham-Diamand
Book Synopsis Cell-Free Synthetic Biology by : Yuan Lu
Download or read book Cell-Free Synthetic Biology written by Yuan Lu and published by Springer. This book was released on 2019-06-27 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes advanced studies in cell-free synthetic biology, an emerging biotechnology that focuses on cell-free protein synthesis and cell-free systems for fundamental and industrial research in areas such as genetic circuit design, small-molecule synthesis, complicated-macromolecule synthesis, unnatural-macromolecule synthesis, high-throughput screening, artificial cells, and biomaterials. Cell-free synthetic biology is now an integral part of developing fields like nanotechnology, materials science, and personalized medicine. The book discusses the main research directions in the development of cell-free systems, as well as a number of applications of cell-free synthetic biology, ranging from structural biology to the human health industry. It is intended for students and researchers in life sciences, synthetic biology, bioengineering, and chemical engineering.
Book Synopsis Nano-Antimicrobials by : Nicola Cioffi
Download or read book Nano-Antimicrobials written by Nicola Cioffi and published by Springer Science & Business Media. This book was released on 2012-02-26 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance have created a pressing need to search for a new generation of antimicrobial agents, which are effective, safe and can be used for the cure of multidrug-resistant microbial infections. Nano-antimicrobials offer effective solutions for these challenges; the details of these new technologies are presented here. The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed.
Book Synopsis The Role of Functional Food Security in Global Health by : Ronald Ross Watson
Download or read book The Role of Functional Food Security in Global Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2018-11-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of Functional Food Security in Global Health presents a collective approach to food security through the use of functional foods as a strategy to prevent under nutrition and related diseases. This approach reflects the views of the Food and Agriculture Organization of the United Nations, the World Health Organization, the World Heart Federation and the American Heart Association who advise Mediterranean, Paleolithic, plant food based diets, and European vegetarian diets for the prevention of cardiovascular disease. In addition, the book also emphasizes the inclusion of spices, herbs and millets, as well as animal foods. This book will be a great resource to the food industry as it presents the most efficient ways to use technology to manufacture slowly absorbed, micronutrient rich functional foods by blending foods that are rich in healthy nutrients.
Book Synopsis State of the Art in Biosensors by : Toonika Rinken
Download or read book State of the Art in Biosensors written by Toonika Rinken and published by BoD – Books on Demand. This book was released on 2013-03-13 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main challenge in biosensor development is their application for various practical tasks to provide a continuous and reliable flow of information about the indicators of natural and industrial processes and the surroundings, so enabling adequate feedback and control. Biosensors can provide essential information, as the quality of life depends mainly on our knowledge about what we breathe, what we eat and how our bodies are able to metabolize the material, which we contact. This book includes 14 chapters, written by 52 authors and is focused on the applications of biosensors for monitoring the parameters of environment, the quality of food and biomarkers of health.
Book Synopsis Bioluminescence & Chemiluminescence by : Larry J. Kricka
Download or read book Bioluminescence & Chemiluminescence written by Larry J. Kricka and published by World Scientific. This book was released on 2002 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the 12th International Symposium on Bioluminescence (BL) and Chemiluminescence (CL) contains up-to-date information on the latest developments in BL and CL presented by scientists from around the world.Light-emitting reactions are now a vital component of many key technologies in research and in routine analytical laboratories OCo replacing radionuclides in many situations. This volume presents a compilation of the latest developments from key experts and leading-edge researchers in this area."
Book Synopsis Biosensors for the Environmental Monitoring of Aquatic Systems by : Damià Barceló
Download or read book Biosensors for the Environmental Monitoring of Aquatic Systems written by Damià Barceló and published by Springer. This book was released on 2009-05-27 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: sector. This ensured eventual transfer of the technology demonstrated at the wo- shops and Technical Meetings to marketable devices. BIOSET provided assistance for researchers from European laboratories to meet to exchange ideas, use equ- ment, and establish a basis for new joint projects. The secretariat of the Concerted Action BIOSET supported the Technical Meetings. There were three Technical Meetings held, two in Berlin in 1997 and 1998, and the third in Barcelona, in April 2000. The goal of these technical meetings was to join different research and industrial teams to evaluate the performance of their biosensor technology in field conditions with common and standardized surface and waste waters. As a result of these field experiments, the additional information that biosensors can offer to environmental monitoring was also evaluated. Thus, these three Technical Meetings were useful accompanying measures and practical additions to the currently organized yearly workshops. The concerted action BIOSET was f- lowed by the SENSPOL network. The 1st SENSPOL Workshop was held on the 9–11 May 2001 on Sensing Technologies for Contaminated Sites and Groundwater at the University of Alcala. There was one special Workshop on “Genotoxicity Biosensing (TECHNOTOX)” supported by the European Commission DG XII D-1 and BIOSET in the year 2000. The TECHNOTOX meeting at the Flemish Institute for Technological Research (VITO) in Mol was organized by Phillippe Corbisier (VITO), Peter-D. Hansen (TU Berlin) and Damia Barcelo (CSIC Barcelona).
Book Synopsis Tools, Techniques and Protocols for Monitoring Environmental Contaminants by : Satinder Kaur Brar
Download or read book Tools, Techniques and Protocols for Monitoring Environmental Contaminants written by Satinder Kaur Brar and published by Elsevier. This book was released on 2019-06-05 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tools, Techniques and Protocols for Monitoring Environmental Contaminants describes information on the strategic integration of available monitoring methods with molecular techniques, with a focus on omics (DNA, RNA and protein based) and molecular imprinted polymer and nanomaterial based advanced biosensors for environmental applications. It discusses the most commonly practiced analytic techniques, such as HPLC, MS, GCMS and traditional biosensors, giving an overview of the benefits of advanced biosensors over commonly practiced methods in the rapid and reliable assessment of environmental contaminants. As environmental contaminants have become one of the serious concerns in terms of their rapid growth and monitoring in the environment, which is often limited due to costly and laborious methods, this book provides a comprehensive update on their removal, the challenges they create for environmental regulatory agencies, and their diverse effects on terrestrial and aquatic environments.
