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Author : Aditya Bagrodia
Publisher :
ISBN 13 : 9781071608609
Total Pages : 278 pages
Book Rating : 4.6/5 (86 download)
Download or read book Testicular Germ Cell Tumors written by Aditya Bagrodia and published by . This book was released on 2020 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Heide Schatten
Publisher : Springer Science & Business Media
ISBN 13 : 1592597416
Total Pages : 421 pages
Book Rating : 4.5/5 (925 download)
Download or read book Germ Cell Protocols written by Heide Schatten and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introd- tion of transgenic technologies and nuclear cloning. Basic knowledge and te- niques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits st- ies of fertility and infertility in mammals including humans. External in vitro fertilization, now a common technique in assisted fertilization has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and asc- ian eggs, now benefits cloning efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of p- ducing live offspring with enormous biomedical, ecological, and economic implications. All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex that carry to- potency, an ability to develop into an entire new organism. The two volumes on germ cells combine techniques in a variety of different systems and have selected those systems that have provided landmarks in advancing our kno- edge on germ cells.
Author : Heide Schatten
Publisher : Springer Science & Business Media
ISBN 13 : 1592597440
Total Pages : 319 pages
Book Rating : 4.5/5 (925 download)
Download or read book Germ Cell Protocols written by Heide Schatten and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex and carry to- potency, an ability to develop into an entire new organism. The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introduction of transgenic te- nologies and nuclear cloning. Basic knowledge and techniques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits studies of fertility and infertility in mammals. External in vitro fertilization, now a common technique in assisted fertilization, has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and ascidian eggs, now benefits techniques designed to increase cl- ing efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of producing live offspring with en- mous biomedical, ecological, and economic implications. The two volumes on germ cells combine techniques in a variety of d- ferent systems; we have selected those systems that have provided landmarks in advancing our knowledge on germ cells.
Author : Marco Barchi
Publisher : Humana
ISBN 13 : 9781071636978
Total Pages : 0 pages
Book Rating : 4.6/5 (369 download)
Download or read book Germ Cell Development written by Marco Barchi and published by Humana. This book was released on 2024-04-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores techniques for the isolation, purification, and establishment of in vitro germ cell (GS) systems at different stages of development in a variety of organisms, including chickens, mice, rats, and humans. The book additionally describes cutting-edge analytic and informatic tools to study germ cell development at the single cell level and meiotic recombination. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Germ Cell Development: Methods and Protocols provides new insight into the understanding of basic biological aspects of germ cell biology, as well as the opportunity for in vitro manipulation of germ cells for toxicology studies and for genetic intervention.
Author : Michael Buszczak
Publisher : Springer Nature
ISBN 13 : 1071632590
Total Pages : 283 pages
Book Rating : 4.0/5 (716 download)
Download or read book Germline Stem Cells written by Michael Buszczak and published by Springer Nature. This book was released on 2023-07-18 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition volume expands on the previous editions with new discussion on the latest techniques and model systems used to study germline stem cells. The chapters in this book cover topics such as analysis of the C. elegans germline stem cell pool; live imaging of the Drosophila testis stem cell niche; standardization of single-cell RNA-sequencing analysis workflow to study Drosophila ovary; 3D analysis of the intact mouse ovary; and derivation and primordial germ cell induction of intermediate pluripotent stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Germline Stem Cells: Methods and Protocols, Third Edition is a valuable resource for all researchers in the germ stem cell community interested in learning more about this developing field.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (88 download)
Download or read book Germ cell protocols written by and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. Lindsay Frazier
Publisher : Springer Science & Business Media
ISBN 13 : 3642389716
Total Pages : 135 pages
Book Rating : 4.6/5 (423 download)
Download or read book Pediatric Germ Cell Tumors written by A. Lindsay Frazier and published by Springer Science & Business Media. This book was released on 2013-10-28 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the entire life course, from prenatal origins of disease through to treatment in adults and late effects of treatment, the editors have produced a book that will be of interest to both pediatric and adult oncologists.
Author : Heide Schatten
Publisher : Humana Press
ISBN 13 : 9781588291219
Total Pages : 316 pages
Book Rating : 4.2/5 (912 download)
Download or read book Germ Cell Protocols written by Heide Schatten and published by Humana Press. This book was released on 2004-03-15 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: All sexually reproducing organisms produce primordial germ cells, a small population of cells that differentiate into gametes of either sex and carry to- potency, an ability to develop into an entire new organism. The study of germ cells has undergone enormous advances in recent years and has entered into an explosive phase of new discoveries with the introduction of transgenic te- nologies and nuclear cloning. Basic knowledge and techniques developed for lower vertebrate and invertebrate systems have facilitated the study of higher vertebrates, including humans. Many experiments that have first been performed on lower vertebrates provided the tools and strategies that could later be applied to other less readily available mammalian systems. The discovery of centrosomes in ascidians and sea urchin eggs now benefits studies of fertility and infertility in mammals. External in vitro fertilization, now a common technique in assisted fertilization, has only been possible as a result of numerous studies in lower systems in which external fertilization is natural. Egg activation, first explored in sea urchin and ascidian eggs, now benefits techniques designed to increase cl- ing efficiency in farm and domestic animals. Gene manipulations and molecular methods have added to the possibilities of producing live offspring with en- mous biomedical, ecological, and economic implications. The two volumes on germ cells combine techniques in a variety of d- ferent systems; we have selected those systems that have provided landmarks in advancing our knowledge on germ cells.
Author : International Agency for Research on Cancer
Publisher :
ISBN 13 : 9789283224372
Total Pages : 400 pages
Book Rating : 4.2/5 (243 download)
Download or read book WHO Classification of Tumours of the Urinary System and Male Genital Organs written by International Agency for Research on Cancer and published by . This book was released on 2016-02-02 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Urinary System and Male Genital Organs is the eighth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. It contains numerous color photographs, MRIs, ultrasound images, CT scans, charts and references.
Author : Yutaka Sawamura
Publisher : Springer Science & Business Media
ISBN 13 : 370916821X
Total Pages : 369 pages
Book Rating : 4.7/5 (91 download)
Download or read book Intracranial Germ Cell Tumors written by Yutaka Sawamura and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intracranial germ cell tumors are a group of uncommon neoplasms of the central nervous system. The clinical features and natural history of these lesions are quite unique and variable. While intracranial germ cell tumors have been a fascination to neurooncologists for decades, the relatively small number of patients seen in any single institution has hampered the important clinical investigation that is so needed. This text is complete with detailed information concerning the epidemiology, pathology, oncological biology, clinical findings, radiology, and treatment options including surgical strategy, radiotherapy, and chemotherapy for this heterogeneous group of neoplasms. The ongoing clinical trials concerning the optimization of therapy are efficiently summarized. An important final segment addresses the late sequelae of therapy which is of great significance since the majority suffering from these tumors are young patients. This first and only book on intracranial germ cell tumors includes excellent and comprehensive data sheets, illustrations, and radiograms. It provides a detailed and outstanding reference source for physicians taking care of patients with intracranial germ cell tumors, and will be a very welcome edition to their reference libraries.
Author : Aditya Bagrodia
Publisher : Humana
ISBN 13 : 9781071608593
Total Pages : 278 pages
Book Rating : 4.6/5 (85 download)
Download or read book Testicular Germ Cell Tumors written by Aditya Bagrodia and published by Humana. This book was released on 2020-11-16 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the latest techniques used to study germ cell tumors (GCTs), including histopathology; in vitro and in vivo techniques for investigating GCT biology; novel methods for detecting minimal residual diseases; and sequencing considerations as they apply to GCTs. Chapters cover topics such as clinical applications of immunohistochemistry in GCTs in men; fluorescence in situ hybridization (FISH) detection of chromosomal 12p anomalies in testicular GCTs; evaluation of chemotherapeutic drugs for treatment of (cisplatin-resistant) germ cell cancer cell lines; targeted methylation analyses; and circulating microRNA panel for malignant GCT diagnosis and monitoring. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Testicular Germ Cell Tumors: Methods and Protocols provides valuable information that is useful for both novice and expert GCT researchers interested in learning more about this field.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309096537
Total Pages : 224 pages
Book Rating : 4.3/5 (9 download)
Download or read book Guidelines for Human Embryonic Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2005-09-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.
Author :
Publisher :
ISBN 13 :
Total Pages : 194 pages
Book Rating : 4.:/5 (327 download)
Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jon M. Oatley
Publisher : Springer Nature
ISBN 13 : 107163139X
Total Pages : 370 pages
Book Rating : 4.0/5 (716 download)
Download or read book Spermatogonial Stem Cells written by Jon M. Oatley and published by Springer Nature. This book was released on 2023-05-30 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest techniques used in the field of mammalian germ cell biology to study key experimental approaches and perspectives for critical analysis of spermatogonial subsets including the rare spermatogonial stem cells (SSCs) pool. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding common pitfalls. Cutting-edge and comprehensive, Spermatogonial Stem Cells: Methods and Protocols is a valuable resource for both new and experiences investigators looking to expand their knowledge in this developing field.
Author : W. G. Jones
Publisher : Pergamon
ISBN 13 :
Total Pages : 490 pages
Book Rating : 4.3/5 (91 download)
Download or read book Germ Cell Tumours III written by W. G. Jones and published by Pergamon. This book was released on 1994 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the Biosciences, Volume 91: Germ Cell Tumours III documents the proceedings of the Third Germ Cell Tumor Conference held in Leeds, UK on September 8-10, 1993. This book focuses on germ cell tumors, which can be cancerous or non-cancerous tumors that normally occur inside the gonads. The topics discussed include the embryological mechanisms of maldescent and tumorigenesis; epidemiology of cryptorchidism; simultaneous bilateral testicular tumors; and mediastinal germ cell tumors. The classification of germ cell tumors; role of positron emission tomography in the assessment of germ ce ...
Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264122818
Total Pages : 16 pages
Book Rating : 4.2/5 (641 download)
Download or read book Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays written by OECD and published by OECD Publishing. This book was released on 2011-07-28 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The ...
Author : Roland Dosch
Publisher : Humana
ISBN 13 : 9781071609729
Total Pages : 383 pages
Book Rating : 4.6/5 (97 download)
Download or read book Germline Development in the Zebrafish written by Roland Dosch and published by Humana. This book was released on 2022-03-06 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt:
