Genomes 5

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Genomes 5

Author : Terry A. Brown
Publisher : CRC Press
ISBN 13 : 1000832287
Total Pages : 549 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Genomes 5 by : Terry A. Brown

Download or read book Genomes 5 written by Terry A. Brown and published by CRC Press. This book was released on 2023-04-28 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with previous Genomes editions, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals, including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised to include new developments in long-read DNA sequencing. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are examples of the applications of metabolomics and systems biology. The final chapter is on genome evolutionn, including the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Genomes 5 is the ideal text for upper-level courses focused on genomes and genomics. Key Features A highly accessible and well-structured book with chapters organized into four parts to aid navigation Superb artwork illustrates the key concepts and mechanisms Each chapter has a set of short-answer questions and in-depth problems to test the reader’s understanding of the material Thoroughly up to date with references to the latest research from the 2020s

Genomes

Author : Terence A. Brown
Publisher :
ISBN 13 :
Total Pages : 608 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genomes by : Terence A. Brown

Download or read book Genomes written by Terence A. Brown and published by . This book was released on 2002 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomes 2 covers modern molecular genetics from the genomics perspective, incorporating major advances made in the past three years, including the sequencing of the human genome, characterization of genome expression and replication processes, and transcriptomics and proteomics. The text is richly illustrated with clear, easy-to-follow, full-color diagrams, which are downloadable from the book's website.

Genomes 4

Author : T. A. Brown
Publisher : Garland Science
ISBN 13 : 1351851292
Total Pages : 520 pages
Book Rating : 4.3/5 (518 download)

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Book Synopsis Genomes 4 by : T. A. Brown

Download or read book Genomes 4 written by T. A. Brown and published by Garland Science. This book was released on 2018-12-07 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids. Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important. Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.

Genome

Author : Matt Ridley
Publisher : Harper Collins
ISBN 13 : 0062253468
Total Pages : 370 pages
Book Rating : 4.0/5 (622 download)

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Book Synopsis Genome by : Matt Ridley

Download or read book Genome written by Matt Ridley and published by Harper Collins. This book was released on 2013-03-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

Combinatorics of Genome Rearrangements

Author : Guillaume Fertin
Publisher : MIT Press
ISBN 13 : 0262062828
Total Pages : 305 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Combinatorics of Genome Rearrangements by : Guillaume Fertin

Download or read book Combinatorics of Genome Rearrangements written by Guillaume Fertin and published by MIT Press. This book was released on 2009 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.

Genomes 5

Author : Terry A. Brown
Publisher :
ISBN 13 : 9780367674076
Total Pages : 0 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis Genomes 5 by : Terry A. Brown

Download or read book Genomes 5 written by Terry A. Brown and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated and rewritten, with 150 new figures Genomes from a wide variety of organisms included, from viruses to humans Techniques fully integrated into the text, including those investigating the genome, transcriptome, and proteome Coverage of expression, regulation, and evolution is on a genomic scale Short answer questions and in-depth problems at the end of each chapter Same structure as Genomes 3 but streamlined

Human Genes and Genomes

Author : Leon E. Rosenberg
Publisher : Academic Press
ISBN 13 : 0123852137
Total Pages : 447 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Human Genes and Genomes by : Leon E. Rosenberg

Download or read book Human Genes and Genomes written by Leon E. Rosenberg and published by Academic Press. This book was released on 2012-05-21 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor's office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and its relevance across disciplines. - Bridges the gap between basic human genetic understanding and one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease - Includes the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more - Explores ethical, legal, regulatory and economic aspects of genomics in medicine - Integrates historical (classical) genetics approach with the latest discoveries in structural and functional genomics

Genes And Genomes

Author : Maxine Singer
Publisher : University Science Books
ISBN 13 : 9780935702170
Total Pages : 964 pages
Book Rating : 4.7/5 (21 download)

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Book Synopsis Genes And Genomes by : Maxine Singer

Download or read book Genes And Genomes written by Maxine Singer and published by University Science Books. This book was released on 1991 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: The celebrated authors present an in-depth overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms. They emphasize the experimental aspects of molecular genetics, offering a complete introduction to both principles and methods. "Excellent, suitably detailed and superbly written." Philip Leder, Harvard Medical School

Adaptive Evolution of Genes and Genomes

Author : Austin L. Hughes
Publisher :
ISBN 13 : 9780195116267
Total Pages : 286 pages
Book Rating : 4.1/5 (162 download)

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Book Synopsis Adaptive Evolution of Genes and Genomes by : Austin L. Hughes

Download or read book Adaptive Evolution of Genes and Genomes written by Austin L. Hughes and published by . This book was released on 1999 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable book thoroughly examines adaptive evolution at the DNA level while taking a comprehensive look at the research being done in the area. It presents useful cases where signals of adaptive evolution are detected through neutral molecular evolution, providing a powerful strategy for testing the Darwinian hypothesis of natural selection. By bridging the gap between research on molecular and phenotype evolution and contributing to the unification of the biological sciences, this book will especially appeal to researchers and graduate students in the field of evolutionary biology. Also, with its focus on particular protein molecules and on specific domains of these proteins, it will benefit a wider audience of both evolutionary and functional biologists.

Molecular and Genome Evolution

Author : Dan Graur
Publisher : Sinauer
ISBN 13 : 9781605354699
Total Pages : 0 pages
Book Rating : 4.3/5 (546 download)

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Book Synopsis Molecular and Genome Evolution by : Dan Graur

Download or read book Molecular and Genome Evolution written by Dan Graur and published by Sinauer. This book was released on 2015-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the driving forces behind the evolutionary process at the molecular and genome levels, the effects of the various molecular mechanisms on the structure of genes, proteins, and genomes, the methodology and the analytical tools involved in dealing with molecular data from an evolutionary perspective, and the logic of evolutionary hypothesis testing. Evolutionary phenomena at the molecular level are detailed in a way that can be understood without much prerequisite knowledge of molecular biology, evolution, or mathematics. Numerous examples that support and clarify the theoretical arguments and methodological discussions are included.

From Genes to Genomes

Author : Jeremy W. Dale
Publisher : John Wiley & Sons
ISBN 13 : 1119954274
Total Pages : 401 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis From Genes to Genomes by : Jeremy W. Dale

Download or read book From Genes to Genomes written by Jeremy W. Dale and published by John Wiley & Sons. This book was released on 2011-11-28 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.

Genetics

Author : Daniel L. Hartl
Publisher : Jones & Bartlett Publishers
ISBN 13 : 1449626114
Total Pages : 830 pages
Book Rating : 4.4/5 (496 download)

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Book Synopsis Genetics by : Daniel L. Hartl

Download or read book Genetics written by Daniel L. Hartl and published by Jones & Bartlett Publishers. This book was released on 2012 with total page 830 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioinformatics and Computational Biology

Author : Sanguthevar Rajasekaran
Publisher : Springer
ISBN 13 : 3642007279
Total Pages : 463 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Bioinformatics and Computational Biology by : Sanguthevar Rajasekaran

Download or read book Bioinformatics and Computational Biology written by Sanguthevar Rajasekaran and published by Springer. This book was released on 2009-04-22 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the First International on Bioinformatics and Computational Biology, BICoB 2007, held in New Orleans, LA, USA, in April 2007. The 30 revised full papers presented together with 10 invited lectures were carefully reviewed and selected from 72 initial submissions. The papers address current research in the area of bioinformatics and computational biology fostering the advancement of computing techniques and their application to life sciences in topics such as genome analysis sequence analysis, phylogenetics, structural bioinformatics, analysis of high-throughput biological data, genetics and population analysis, as well as systems biology.

Mapping and Sequencing the Human Genome

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309038405
Total Pages : 128 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping and Sequencing the Human Genome by : National Research Council

Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

The Postgenomic Condition

Author : Jenny Reardon
Publisher : University of Chicago Press
ISBN 13 : 022651045X
Total Pages : 320 pages
Book Rating : 4.2/5 (265 download)

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Book Synopsis The Postgenomic Condition by : Jenny Reardon

Download or read book The Postgenomic Condition written by Jenny Reardon and published by University of Chicago Press. This book was released on 2017-12-29 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue

Heritable Human Genome Editing

Author : The Royal Society
Publisher : National Academies Press
ISBN 13 : 0309671132
Total Pages : 239 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Heritable Human Genome Editing by : The Royal Society

Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Computational Methods For Understanding Bacterial And Archaeal Genomes

Author : Ying Xu
Publisher : World Scientific
ISBN 13 : 1908979011
Total Pages : 494 pages
Book Rating : 4.9/5 (89 download)

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Book Synopsis Computational Methods For Understanding Bacterial And Archaeal Genomes by : Ying Xu

Download or read book Computational Methods For Understanding Bacterial And Archaeal Genomes written by Ying Xu and published by World Scientific. This book was released on 2008-08-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses./a