Genome Wide View On The Physiology Of Vitamin D

Download Genome Wide View On The Physiology Of Vitamin D full books in PDF, epub, and Kindle. Read online Genome Wide View On The Physiology Of Vitamin D ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Genome-wide view on the physiology of vitamin D

Author : Carsten Carlberg
Publisher : Frontiers E-books
ISBN 13 : 2889193497
Total Pages : 195 pages
Book Rating : 4.8/5 (891 download)

DOWNLOAD NOW!

Book Synopsis Genome-wide view on the physiology of vitamin D by : Carsten Carlberg

Download or read book Genome-wide view on the physiology of vitamin D written by Carsten Carlberg and published by Frontiers E-books. This book was released on 2014-12-05 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.

Genome-wide View on the Physiology of Vitamin D.

Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

DOWNLOAD NOW!

Book Synopsis Genome-wide View on the Physiology of Vitamin D. by :

Download or read book Genome-wide View on the Physiology of Vitamin D. written by and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980's. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.

Vitamin D

Author : Michael F. Holick
Publisher : Springer Science & Business Media
ISBN 13 : 1475728611
Total Pages : 456 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D by : Michael F. Holick

Download or read book Vitamin D written by Michael F. Holick and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.

Vitamin D

Author : Martin Hewison
Publisher : Academic Press
ISBN 13 : 0128099666
Total Pages : 1182 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D by : Martin Hewison

Download or read book Vitamin D written by Martin Hewison and published by Academic Press. This book was released on 2017-12-14 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease. Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis, human physiology, diagnosis and management, nutrition, sunlight, genetics and vitamin D deficiency Volume II of this collection presents a clinical focus on disorders, analogs, cancer; immunity, inflammation and disease and therapeutic applications

Vitamin D Hormone

Author :
Publisher : Academic Press
ISBN 13 : 0128052406
Total Pages : 548 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D Hormone by :

Download or read book Vitamin D Hormone written by and published by Academic Press. This book was released on 2016-01-30 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on vitamin D hormone. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels

Vitamin D

Author : Anthony W. Norman
Publisher : de Gruyter
ISBN 13 :
Total Pages : 1044 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D by : Anthony W. Norman

Download or read book Vitamin D written by Anthony W. Norman and published by de Gruyter. This book was released on 1991 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Vitamin D".

Nutrigenomics

Author : Carsten Carlberg
Publisher : Springer
ISBN 13 : 3319304151
Total Pages : 237 pages
Book Rating : 4.3/5 (193 download)

DOWNLOAD NOW!

Book Synopsis Nutrigenomics by : Carsten Carlberg

Download or read book Nutrigenomics written by Carsten Carlberg and published by Springer. This book was released on 2016-06-11 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating area of Nutrigenomics describes this daily communication between diet, food and nutrients, their metabolites and our genome. This book describes how nutrition shapes human evolution and demonstrates its consequences for our susceptibility to diseases, such as diabetes and atherosclerosis. Inappropriate diet can yield stress for our cells, tissues and organs and then it is often associated with low-grade chronic inflammation. Overnutrition paired with physical inactivity leads to overweight and obesity and results in increased burden for a body that originally was adapted for a life in the savannas of East Africa. Therefore, this textbook does not discuss a theoretical topic in science, but it talks about real life, and our life-long “chat” with diet. We are all food consumers, thus each of us is concerned by the topic of this book and should be aware of its mechanisms. The purpose of this book is to provide an overview on the principles of nutrigenomics and their relation to health or disease. We are not aiming to compete with more comprehensive textbooks on molecular nutrition, evolutionary biology, genomics, gene regulation or metabolic diseases, but rather will focus on the essentials and will combine, in a compact form, elements from different disciplines. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule “a picture tells more than thousand words”. The content of this book is based on the lecture course “Nutrigenomics”, which is held since 2003 once per year by Prof. Carlberg at the University of Eastern Finland in Kuopio. The book is subdivided into three sections and twelve chapters. Following the "Introduction" there are sections on the "Molecular genetic basis" and the "Links to disease", which take a view on nutrigenomics from the perspective of molecular mechanisms or from the causes of metabolic diseases, respectively. Besides its value as a textbook, Nutrigenomics will be a usefull reference for individuals working in biomedicine.

Immune Regulation

Author : Marc Feldmann
Publisher : Springer Science & Business Media
ISBN 13 : 1461249961
Total Pages : 384 pages
Book Rating : 4.4/5 (612 download)

DOWNLOAD NOW!

Book Synopsis Immune Regulation by : Marc Feldmann

Download or read book Immune Regulation written by Marc Feldmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukocyte culture conferences have a long pedigree. This volume records some of the scientific highlights of the 16th such annual con ference, and is a witness to the continuing evolution and popularity of leukocyte culture and of immunology. There is strong evidence of the widening horizons of immunology, both technically, with the obviously major impact of molecular biology into our understanding of cellular processes, and also conceptually. Traditionally, the 'proceedings' of these conferences have been published. But have the books produced really recorded the major part of the conference, the informal, friendly, but intense and some times heated exchanges that take place between workers in tackling very similar problems and systems and which are at the heart of every successful conference? Unfortunately this essence cannot be incorpo rated by soliciting manuscripts. For this reason, we have changed the format of publication, retaining published versions of the symposium papers, but requesting the workshop chairmen to produce a summary of the major new observations and areas of controversy highlighted in their sessions, as a vehicle for defining current areas of interest and debate. Not an easy task, as the workshop topics were culled from the abstracts submitted by the participants, rather than being on predefined topics. The unseasonal warmth in Cambridge was reflected in the atmos phere of the conference, the organization of which benefited from the administrative skills of Jean Bacon, Philippa Wells, Mr. Peter Irving, and Mrs.

Stroke Genetics

Author : Hugh S. Markus
Publisher : Oxford Medical Publications
ISBN 13 : 0198515863
Total Pages : 362 pages
Book Rating : 4.1/5 (985 download)

DOWNLOAD NOW!

Book Synopsis Stroke Genetics by : Hugh S. Markus

Download or read book Stroke Genetics written by Hugh S. Markus and published by Oxford Medical Publications. This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Principles of Bone Biology

Author : John P. Bilezikian
Publisher : Academic Press
ISBN 13 : 0080568750
Total Pages : 2074 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis Principles of Bone Biology by : John P. Bilezikian

Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Extraskeletal Effects of Vitamin D

Author : Emilia Pauline Liao
Publisher : Humana Press
ISBN 13 : 3319737422
Total Pages : 258 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Extraskeletal Effects of Vitamin D by : Emilia Pauline Liao

Download or read book Extraskeletal Effects of Vitamin D written by Emilia Pauline Liao and published by Humana Press. This book was released on 2018-04-23 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the skeletal effects of vitamin D are well-documented, the role and importance of vitamin D outside of bone health has not been well-established. Vitamin D receptors are located in nearly every tissue of the body, and low levels of vitamin D are associated with a range of various diseases. This book provides an in-depth examination of these extraskeletal effects of vitamin D and the associations between vitamin D deficiency and various disease states. Beginning with a review of the biochemistry and physiology of vitamin D, subsequent chapters investigate its relationship to autoimmune and infectious diseases, various forms of cancer, endocrine issues such as diabetes, obesity and reproductive function, cardiovascular disease and muscle weakness. Concluding chapters discuss the role of vitamin D in neurological disorders, including Alzheimer's Disease, and cognitive function. Focusing on extraskeletal effects only across a range of conditions, Extraskeletal Effects of Vitamin D will be an important resource for clinical endocrinologists and primary care physicians.

Feldman and Pike’s Vitamin D

Author : Martin Hewison
Publisher : Elsevier
ISBN 13 : 0323913903
Total Pages : 1232 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!

Book Synopsis Feldman and Pike’s Vitamin D by : Martin Hewison

Download or read book Feldman and Pike’s Vitamin D written by Martin Hewison and published by Elsevier. This book was released on 2023-10-28 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D deficiency is a worldwide problem linked to numerous diseases affecting men, women, and children of all ages. Enormous progress in the study of vitamin D has been made since the first edition of this highly-acclaimed book was published nearly 20 years ago, and current research continues to draw headlines. Feldman and Pike’s Vitamin D, Fifth Edition continues to build on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. The two comprehensive volumes provide investigators, clinicians, and students with a comprehensive, definitive, and up-to-date compendium of the diverse scientific and clinical aspects of vitamin D, where each area is covered by both basic and clinical experts in the field. In Volume I: Biochemistry, Physiology and Diagnostics, international experts in endocrinology, bone biology, and human physiology take readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multi-faceted actions of vitamin D relating both to skeletal and extra-skeletal action. Researchers from all areas of vitamin D will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic, proteomic and metabolomic insights into the mechanisms of disease. Volume II: Health, Disease and Therapy authoritatively covers the evidence for new roles of vitamin D, ranging from organ transplantation to cancer, diabetes, inflammatory bowel disease, multiple sclerosis, and renal disease. The coverage is appropriately broad, drawing on aspects of internal medicine, pediatrics, nutrition, orthopedics, oncology, neurology, obstetrics and gynecology, and immunology, as well as, new areas for vitamin D including liver metabolism, veterinary medicine and ICU care – including COVID-19. Clinical researchers will gain a strong understanding of the molecular basis for a particular disease and better understand future directions for research in this still-growing field. • A comprehensive reference ranging from basic biochemistry, cell biology, and physiology principles to the clinical diagnostic and management implications of vitamin D • Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of vitamin D, as opposed to searching through thousands of journal articles • Chapters written by the most prominent and well-published names in the field

Comprehensive Toxicology

Author :
Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!

Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Sunlight, Vitamin D and Skin Cancer

Author : Jörg Reichrath
Publisher : Springer Nature
ISBN 13 : 3030462277
Total Pages : 428 pages
Book Rating : 4.0/5 (34 download)

DOWNLOAD NOW!

Book Synopsis Sunlight, Vitamin D and Skin Cancer by : Jörg Reichrath

Download or read book Sunlight, Vitamin D and Skin Cancer written by Jörg Reichrath and published by Springer Nature. This book was released on 2020-09-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.

Vitamin D and Human Health

Author : Simon Spedding
Publisher : MDPI
ISBN 13 : 3038975869
Total Pages : 307 pages
Book Rating : 4.0/5 (389 download)

DOWNLOAD NOW!

Book Synopsis Vitamin D and Human Health by : Simon Spedding

Download or read book Vitamin D and Human Health written by Simon Spedding and published by MDPI. This book was released on 2019-02-21 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Vitamin D and Human Health" that was published in Nutrients

Immune-Modulatory Effects of Vitamin D

Author : Susu M. Zughaier
Publisher : Frontiers Media SA
ISBN 13 : 2889661741
Total Pages : 177 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Immune-Modulatory Effects of Vitamin D by : Susu M. Zughaier

Download or read book Immune-Modulatory Effects of Vitamin D written by Susu M. Zughaier and published by Frontiers Media SA. This book was released on 2020-12-16 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Classic and Pleiotropic Actions of Vitamin D

Author : Pawel Pludowski
Publisher : Frontiers Media SA
ISBN 13 : 2889630080
Total Pages : 169 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Classic and Pleiotropic Actions of Vitamin D by : Pawel Pludowski

Download or read book Classic and Pleiotropic Actions of Vitamin D written by Pawel Pludowski and published by Frontiers Media SA. This book was released on 2019-09-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vitamin D is widely advertised as a solution for a large spectrum of diseases and health issues. Growing number of pharmaceuticals and supplements containing vitamin D, increasing availability of them in pharmacies, stores, online distribution and, sometimes, an intrusive commercial publicity campaigns have raised great interest, and have triggered reasonable controversies and fears. The self-administration of high doses of vitamin D has also appeared major concern in society. There is an increasing number of dilemmas regarding side effects including nephrocalcinosis, urinary stone disease, drug interactions and other adversity. On the other hand, it is recognized that vitamin D deficiency is a global health problem with potential negative consequences on health, welfare and morbidity during growth and adulthood, and therefore influencing health care services worldwide. According to current published reports, the vitamin D deficiency is regarded a significant risk factor for several civilization diseases including cancer, cardiovascular diseases, hypertension, autoimmune and metabolic disorders, infectious diseases and many other chronic conditions. Thus, it is essential to discuss vividly, and share scientific reports and evidence demonstrating both the safety issues and the significance of vitamin D for health of children, adolescents, middle-aged men and women, professionally active individuals, and seniors. This eBook is a collection of articles presented at the 3rd International Conference “Vitamin D - Minimum, Maximum, Optimum” (EVIDAS 2017) held in Warsaw (Poland) on September 22–23, 2017. EVIDAS (European Vitamin D Association) is a scientific society focused on vitamin D and its meaning for human health.