Genetics of Melanoma

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Author :
Publisher : Springer
ISBN 13 : 1493935542
Total Pages : 291 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Genetics of Melanoma by : Carlos A. Torres-Cabala

Download or read book Genetics of Melanoma written by Carlos A. Torres-Cabala and published by Springer. This book was released on 2016-05-11 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.

Melanoma Development

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Author :
Publisher : Springer
ISBN 13 : 9783319823225
Total Pages : 0 pages
Book Rating : 4.8/5 (232 download)

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Book Synopsis Melanoma Development by : Anja K. Bosserhoff

Download or read book Melanoma Development written by Anja K. Bosserhoff and published by Springer. This book was released on 2018-07-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Recent Advances in the Biology, Therapy and Management of Melanoma

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535109766
Total Pages : 388 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Recent Advances in the Biology, Therapy and Management of Melanoma by : Lester Davids

Download or read book Recent Advances in the Biology, Therapy and Management of Melanoma written by Lester Davids and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.

Human Skin Cancers

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Publisher : BoD – Books on Demand
ISBN 13 : 1789230942
Total Pages : 214 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Human Skin Cancers by : Miroslav Blumenberg

Download or read book Human Skin Cancers written by Miroslav Blumenberg and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.

Cutaneous Melanoma

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Cutaneous Melanoma by :

Download or read book Cutaneous Melanoma written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Genetics and Psychotherapy

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Author :
Publisher : Springer
ISBN 13 : 3319645501
Total Pages : 1189 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Cancer Genetics and Psychotherapy by : Parvin Mehdipour

Download or read book Cancer Genetics and Psychotherapy written by Parvin Mehdipour and published by Springer. This book was released on 2017-09-20 with total page 1189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide the readers with the most comprehensive and latest accounts of research and development in this field by emphasizing on the manner of relation between doctors and cancer patients in direction of improving the patients’ style of life. This book, partly, will deal with psychotherapy by considering cancer patients, benefits, hazards and also social impacts including life style. The social supports as the key and influential paradigms will be challenged as a comparative insight by considering the global unity in order to provide a reasonable model to improve the interaction between cancer and psychological nest. In this book, the real stories of cancer patient will be also provided. The initial insight of sections includes: 1) Brief classifications and key points of clinical and histopatological aspects of each organ. 2) Brief view of genetic alterations in each organ. 3) Therapeutic aspects. 4) Brief classifications and key points of Psychology in cancer. 5) The interactions of clinical aspects with psychological field.

Sunlight, Vitamin D and Skin Cancer

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Publisher : Springer Nature
ISBN 13 : 3030462277
Total Pages : 428 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Sunlight, Vitamin D and Skin Cancer by : Jörg Reichrath

Download or read book Sunlight, Vitamin D and Skin Cancer written by Jörg Reichrath and published by Springer Nature. This book was released on 2020-09-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.

Melanoma

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Author :
Publisher : Springer
ISBN 13 : 3319783106
Total Pages : 653 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Melanoma by : Adam I. Riker

Download or read book Melanoma written by Adam I. Riker and published by Springer. This book was released on 2018-06-06 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text serves as a very useful clinical guide and realistic approach to the clinical management of melanoma. Primary care physicians, specialists from varying areas of medical practice and numerous other healthcare providers will find this text to be quite useful as a standard daily reference and use in the office setting. It provides a clear and concise source of information in order to make real-life, evidence-based decisions for all aspects of management for cutaneous melanoma. This book also provides the latest breakthroughs in melanoma research, ranging from recent discoveries in genomics and epigenetics, to newly identified genes that have been selectively targeted for the development of a personalized approach to treatment. All chapters are written by specialists and true experts within their respective fields, incorporating the latest scientific, clinical and evidence-based medicine for melanoma (and non-melanoma skin cancers). This up-to-date information can be easily applied and translated to the clinical setting for the melanoma patient.

Cancer Cytogenetics

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118795512
Total Pages : 645 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis Cancer Cytogenetics by : Sverre Heim

Download or read book Cancer Cytogenetics written by Sverre Heim and published by John Wiley & Sons. This book was released on 2015-06-29 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible

Molecular Diagnostics for Melanoma

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Publisher : Humana Press
ISBN 13 : 9781627037266
Total Pages : 0 pages
Book Rating : 4.0/5 (372 download)

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Book Synopsis Molecular Diagnostics for Melanoma by : Magdalena Thurin

Download or read book Molecular Diagnostics for Melanoma written by Magdalena Thurin and published by Humana Press. This book was released on 2013-11-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Molecular Diagnostics for Melanoma: Methods and Protocols, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage. With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients. Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Protocols seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.

Medical Genetics of Melanoma

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Publisher :
ISBN 13 : 9781545053478
Total Pages : 250 pages
Book Rating : 4.0/5 (534 download)

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Book Synopsis Medical Genetics of Melanoma by : Garden Grove Garden Grove Press

Download or read book Medical Genetics of Melanoma written by Garden Grove Garden Grove Press and published by . This book was released on 2017-03-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This article collection reviews the medical genetics of melanoma and includes 25 papers by various authors. Topics include: Matrix Metalloproteinase-9 (MMP-9) polymorphisms in patients with cutaneous malignant melanoma; The stable traits of melanoma genetics: an alternate approach to target discovery; Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma; Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naive patient melanomas; Discrepant alterations in main candidate genes among multiple primary melanomas; MiR-21: an environmental driver of malignant melanoma?; Immunotherapy Bridge 2016 and Melanoma Bridge 2016: meeting abstracts; Serum 25-hydroxyvitamin D3 levels and vitamin D receptor variants in melanoma patients from the Mediterranean area of Barcelona; A case report of a patient with metastatic ocular melanoma who experienced a response to treatment with the BRAF inhibitor vemurafenib; Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies; Melanoma genome evolution across species; Clinical application of genetic testing for posterior uveal melanoma; AurkA inhibitors enhance the effects of B-RAF and MEK inhibitors in melanoma treatment; Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case-control study; Future perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010"; The association between Parkinson's disease and melanoma: a systematic review and meta-analysis; Gene expression profiling of melanoma cells - searching the haystack; The immune-related role of BRAF in melanoma; Vemurafenib resistance reprograms melanoma cells towards glutamine dependence; Melanoma cells influence the differentiation pattern of human epidermal keratinocytes; Exome sequencing in primary melanoma identifies novel drivers of melanoma progression; Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face; Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy; Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study; Melanoma risk loci as determinants of melanoma recurrence and survival. Proceeds from the sale of this book go to the support of an elderly disabled person.

Melanoma Development

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Publisher : Springer
ISBN 13 : 3319413198
Total Pages : 443 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Melanoma Development by : Anja K. Bosserhoff

Download or read book Melanoma Development written by Anja K. Bosserhoff and published by Springer. This book was released on 2017-01-20 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

WHO Classification of Skin Tumours

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Author :
Publisher : International Agency for Research on Cancer
ISBN 13 : 9789283224402
Total Pages : 0 pages
Book Rating : 4.2/5 (244 download)

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Book Synopsis WHO Classification of Skin Tumours by : Centre international de recherche sur le cancer

Download or read book WHO Classification of Skin Tumours written by Centre international de recherche sur le cancer and published by International Agency for Research on Cancer. This book was released on 2018-09-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Classification of Skin Tumours is the 11th volume in the 4th edition of the WHO series on the classification of human tumours. The series (also known as the Blue Books) has long been regarded by pathologists as the gold standard for the diagnosis of tumours, and it is an indispensable guide for the design of evaluations, clinical trials, and studies involving cancer. These authoritative and concise reference books provide an international standard for anyone involved in cancer research or the care of cancer patients. Diagnostic criteria, pathological features, and genetic and other associated molecular alterations are described in a disease-oriented manner. This volume updates the existing ICD-O codes and provides new codes for use in epidemiology and cancer registration. It also provides information on clinical features, pathology, genetics, prognosis, and protective factors for each of the tumour types covered. The editors expect that this volume will be of particular interest to pathologists, oncologists, and dermatologists who manage or research skin tumours. Sections are included on all recognized neoplasms (and their variants) of the skin and its adnexae. Since the previous edition, there have been particularly substantial changes to the classification of melanoma, based on the latest information from genetic and molecular studies.

Practical Medical Oncology Textbook

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Publisher : Springer Nature
ISBN 13 : 3030560511
Total Pages : 1104 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Practical Medical Oncology Textbook by : Antonio Russo

Download or read book Practical Medical Oncology Textbook written by Antonio Russo and published by Springer Nature. This book was released on 2021-10-06 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.

From Melanocytes to Melanoma

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 159259994X
Total Pages : 673 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis From Melanocytes to Melanoma by : Vincent J. Hearing

Download or read book From Melanocytes to Melanoma written by Vincent J. Hearing and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Dermato-Oncology Study Guide

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Author :
Publisher : Springer Nature
ISBN 13 : 3030534375
Total Pages : 389 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Dermato-Oncology Study Guide by : Vincent Liu

Download or read book Dermato-Oncology Study Guide written by Vincent Liu and published by Springer Nature. This book was released on 2021-03-23 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides clinicians, clinicians-in-training and researchers with a unique rapid-access educational resource on the spectrum of issues at the intersection of skin and malignancy. In it, there is clinical detail provided on how the skin reveals systemic malignancy via cutaneous metastases, genodermatoses or paraneoplastic dermatoses. At the same time, it reviews pharmacologic treatment of internal malignancy and how this can result in cutaneous adverse reactions; conversely, therapeutics for skin conditions can increase risk for internal malignancy. As arguably the most significant cutaneous malignancy, melanoma receives specific attention for its metastatic potential, current diagnostic advances, and recent therapeutic breakthroughs. Dermato-Oncology Study Guide: Essential Text and Review serves a critical educational need for clinicians caring for patients with systemic malignancy by creating an easy-to-use resource that provides practical tools to recognize skin signs of internal malignancy. Furthermore it helps in anticipating and managing adverse reactions of therapeutics for systemic malignancy, and gives the reader the opportunity to weigh the risks of malignancy of pharmacologic agents for skin disease.

Cancer Survival and Prevalence in Australia

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Author :
Publisher : AIHW
ISBN 13 : 1742493386
Total Pages : 200 pages
Book Rating : 4.7/5 (424 download)

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Book Synopsis Cancer Survival and Prevalence in Australia by : Australian Institute of Health and Welfare

Download or read book Cancer Survival and Prevalence in Australia written by Australian Institute of Health and Welfare and published by AIHW. This book was released on 2012 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report presents the latest national survival and prevalence statistics for cancers in Australia from 1982 to 2010. Survival from cancer is a key indicator of cancer prognosis, control and treatment. It refers to the probability of being alive for a given amount of time after diagnosis and reflects the severity of a cancer diagnosis.