Genetics and Genomics of Cotton

Download Genetics and Genomics of Cotton PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387708103
Total Pages : 515 pages
Book Rating : 4.3/5 (877 download)

DOWNLOAD NOW!


Book Synopsis Genetics and Genomics of Cotton by : Andrew H. Paterson

Download or read book Genetics and Genomics of Cotton written by Andrew H. Paterson and published by Springer Science & Business Media. This book was released on 2009-03-11 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Gossypium (cotton) genus presents novel opportunities to advance our understanding of the natural world and its organic evolution. In this book, advances of the past decade are summarized and synthesized to elucidate the current state of knowledge of the structure, function, and evolution of the Gossypium genome, and progress in the application of this knowledge to cotton improvement. This book provides the first comprehensive reference on cotton genomics.

Cotton Precision Breeding

Download Cotton Precision Breeding PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030645045
Total Pages : 459 pages
Book Rating : 4.0/5 (36 download)

DOWNLOAD NOW!


Book Synopsis Cotton Precision Breeding by : Mehboob-ur- Rahman

Download or read book Cotton Precision Breeding written by Mehboob-ur- Rahman and published by Springer Nature. This book was released on 2021-06-08 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton, the most important natural fiber crop, has been improved by conventional breeding—largely through planned hybridization of different cotton genotypes, since the discovery of Mendelian genetics. All these efforts resulted in the development of resilient high yielding cotton varieties. However, the progress through conventional breeding procedures is slow because of long lag periods for developing a variety, little control over the new genetic combinations, unwanted traits and lack of foolproof performance testing system. Genomic assays discovered over the last two decades have made it possible to understand the “language” of the genome by associating the genes with specific traits. Together with the more recently established gene-editing tools like CRISPR-Cas9, the cotton genome can be tailored much more precisely than ever before. In this regard, genetic information has been harnessed, through (i) sequencing of the progenitor and cultivated cotton species, (ii) ongoing mega pan-genome sequencing projects, (iii) genetic and physical mapping, and (iv) introgression of genes from alien sources, that resulted in the development of resilient cotton cultivars. These technologies have been deployed or are attempting to overcome the challenges of water shortage, excessive heat in most cotton growing regions, infectious diseases and infestation of insect pests, as well as rising production cost, for sustainable cotton production beyond 2030. In this book, new knowledge generated by the cotton research community and its application for developing resilient cotton are comprehensively summarized. This book contributed by well-known cotton researchers is a timely collection of the challenges and successes of precision cotton breeding in a changing environment.

Polyploidy and Genome Evolution

Download Polyploidy and Genome Evolution PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642314414
Total Pages : 416 pages
Book Rating : 4.6/5 (423 download)

DOWNLOAD NOW!


Book Synopsis Polyploidy and Genome Evolution by : Pamela Soltis

Download or read book Polyploidy and Genome Evolution written by Pamela Soltis and published by Springer Science & Business Media. This book was released on 2012-10-03 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyploidy – whole-genome duplication (WGD) – is a fundamental driver of biodiversity with significant consequences for genome structure, organization, and evolution. Once considered a speciation process common only in plants, polyploidy is now recognized to have played a major role in the structure, gene content, and evolution of most eukaryotic genomes. In fact, the diversity of eukaryotes seems closely tied to multiple WGDs. Polyploidy generates new genomic interactions – initially resulting in “genomic and transcriptomic shock” – that must be resolved in a new polyploid lineage. This process essentially acts as a “reset” button, resulting in genomic changes that may ultimately promote adaptive speciation. This book brings together for the first time the conceptual and theoretical underpinnings of polyploid genome evolution with syntheses of the patterns and processes of genome evolution in diverse polyploid groups. Because polyploidy is most common and best studied in plants, the book emphasizes plant models, but recent studies of vertebrates and fungi are providing fresh perspectives on factors that allow polyploid speciation and shape polyploid genomes. The emerging paradigm is that polyploidy – through alterations in genome structure and gene regulation – generates genetic and phenotypic novelty that manifests itself at the chromosomal, physiological, and organismal levels, with long-term ecological and evolutionary consequences.

Cotton Breeding and Biotechnology

Download Cotton Breeding and Biotechnology PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1000535622
Total Pages : 533 pages
Book Rating : 4.0/5 (5 download)

DOWNLOAD NOW!


Book Synopsis Cotton Breeding and Biotechnology by : Zulqurnain Khan

Download or read book Cotton Breeding and Biotechnology written by Zulqurnain Khan and published by CRC Press. This book was released on 2022-03-14 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton Breeding and Biotechnology presents information on one of the most economically important crops of the world, cotton. This book contains chapters on the history of cotton; breeding approaches; technologies for increasing germination, crop growth and yield; and fiber quality issues. It emphasizes sustainable development in the cotton industry analysing the progress of breeding technologies under environmental adversity. The book explores the national and global status of cotton crop, including cotton production, possible impacts of climate change, and the vulnerability of cotton to pest infestations and disease attacks. Features Focuses on cotton breeding and biotechnology Proposes ideas, data, and strategies to mount breeding programs for enhancing cotton production Details strategies for cotton quality improvement against abiotic and biotic stresses Emphasizes the revival of cotton in Pakistan and South Asian region This book is useful to researchers, cotton breeders and growers, farmers, and the agriculture industry.

Past, Present and Future Trends in Cotton Breeding

Download Past, Present and Future Trends in Cotton Breeding PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789230764
Total Pages : 186 pages
Book Rating : 4.7/5 (892 download)

DOWNLOAD NOW!


Book Synopsis Past, Present and Future Trends in Cotton Breeding by : Mehboob-Ur- Rahman

Download or read book Past, Present and Future Trends in Cotton Breeding written by Mehboob-Ur- Rahman and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton, a source of natural fiber for textile industry, has a long breeding history aiming at increasing cotton fiber yield and its quality. Newly developed cotton varieties poorly respond in low-input environments. Secondly, the impact of changing climate may threaten the cotton production in the future. To address these challenges, efforts toward the development of resilient cotton varieties have been initiated using genetic and modern genomic approaches. In this book, research updates on cotton fiber types and properties, DNA markers for selecting desirable cotton plants, and cotton fiber genomics were compiled. Also, the modern breeding trends including development of transgenic cotton and the biosafety studies and possibilities of improving cotton genome using modern genome editing tools were also compressively discussed.

Physiology of Cotton

Download Physiology of Cotton PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9048131952
Total Pages : 563 pages
Book Rating : 4.0/5 (481 download)

DOWNLOAD NOW!


Book Synopsis Physiology of Cotton by : James McD. Stewart

Download or read book Physiology of Cotton written by James McD. Stewart and published by Springer Science & Business Media. This book was released on 2009-11-04 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton production today is not to be undertaken frivolously if one expects to profit by its production. If cotton production is to be sustainable and produced profitably, it is essential to be knowledgeable about the growth and development of the cotton plant and in the adaptation of cultivars to the region as well as the technology available. In addition, those individuals involved in growing cotton should be familiar with the use of management aids to know the most profitable time to irrigate, apply plant growth regulators, herbicides, foliar fertilizers, insecticides, defoliants, etc. The chapters in this book were assembled to provide those dealing with the production of cotton with the basic knowledge of the physiology of the plant required to manage the cotton crop in a profitable manner.

Applied Plant Genomics and Biotechnology

Download Applied Plant Genomics and Biotechnology PDF Online Free

Author :
Publisher : Woodhead Publishing
ISBN 13 : 0081000715
Total Pages : 356 pages
Book Rating : 4.0/5 (81 download)

DOWNLOAD NOW!


Book Synopsis Applied Plant Genomics and Biotechnology by : Palmiro Poltronieri

Download or read book Applied Plant Genomics and Biotechnology written by Palmiro Poltronieri and published by Woodhead Publishing. This book was released on 2015-01-27 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied plant genomics and biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics, and plants modified to produce high-value pharmaceutical proteins. The book provides an overview of research advances in application of RNA silencing and RNA interference, through Virus-based transient gene expression systems, Virus induced gene complementation (VIGC), Virus induced gene silencing (Sir VIGS, Mr VIGS) Virus-based microRNA silencing (VbMS) and Virus-based RNA mobility assays (VRMA); RNA based vaccines and expression of virus proteins or RNA, and virus-like particles in plants, the potential of virus vaccines and therapeutics, and exploring plants as factories for useful products and pharmaceuticals are topics wholly deepened. The book reviews and discuss Plant Functional Genomic studies discussing the technologies supporting the genetic improvement of plants and the production of plant varieties more resistant to biotic and abiotic stresses. Several important crops are analysed providing a glimpse on the most up-to-date methods and topics of investigation. The book presents a review on current state of GMO, the cisgenesis-derived plants and novel plant products devoid of transgene elements, discuss their regulation and the production of desired traits such as resistance to viruses and disease also in fruit trees and wood trees with long vegetative periods. Several chapters cover aspects of plant physiology related to plant improvement: cytokinin metabolism and hormone signaling pathways are discussed in barley; PARP-domain proteins involved in Stress-Induced Morphogenetic Response, regulation of NAD signaling and ROS dependent synthesis of anthocyanins. Apple allergen isoforms and the various content in different varieties are discussed and approaches to reduce their presence. Euphorbiaceae, castor bean, cassava and Jathropa are discussed at genomic structure, their diseases and viruses, and methods of transformation. Rice genomics and agricultural traits are discussed, and biotechnology for engineering and improve rice varieties. Mango topics are presented with an overview of molecular methods for variety differentiation, and aspects of fruit improvement by traditional and biotechnology methods. Oilseed rape is presented, discussing the genetic diversity, quality traits, genetic maps, genomic selection and comparative genomics for improvement of varieties. Tomato studies are presented, with an overview on the knowledge of the regulatory networks involved in flowering, methods applied to study the tomato genome-wide DNA methylation, its regulation by small RNAs, microRNA-dependent control of transcription factors expression, the development and ripening processes in tomato, genomic studies and fruit modelling to establish fleshy fruit traits of interest; the gene reprogramming during fruit ripening, and the ethylene dependent and independent DNA methylation changes. provides an overview on the ongoing projects and activities in the field of applied biotechnology includes examples of different crops and applications to be exploited reviews and discusses Plant Functional Genomic studies and the future developments in the field explores the new technologies supporting the genetic improvement of plants

World Cotton Germplasm Resources

Download World Cotton Germplasm Resources PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535116223
Total Pages : 324 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!


Book Synopsis World Cotton Germplasm Resources by : Ibrokhim Y. Abdurakhmonov

Download or read book World Cotton Germplasm Resources written by Ibrokhim Y. Abdurakhmonov and published by BoD – Books on Demand. This book was released on 2014-07-02 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preservation of plant germplasm resources is vitally important for mankind to supply food and product security in the globalization and technological advances of the 21st century. Mankind preserved a wealth of available genetic resources of many plant species worldwide. One of the such worldwide plant germplasm resources is available for cotton, a unique natural fiber producing cash crop for mankind. Worldwide cotton germplasm collections exist in Australia, Brazil, China, India, France, Pakistan, Turkey, Russia, United States of America, and Uzbekistan. The objective of World Cotton Germplasm Resources book is to present readers with updated information on existing cotton germplasm resources, highlighting detailed inventory, description, storage conditions, characterization and utilization as well as challenges and perspectives. This book should be a comprehensive encyclopedic reading source for plant research community and students to gather important information on worldwide cotton germplasm resources.

Polyploid and Hybrid Genomics

Download Polyploid and Hybrid Genomics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118552849
Total Pages : 646 pages
Book Rating : 4.1/5 (185 download)

DOWNLOAD NOW!


Book Synopsis Polyploid and Hybrid Genomics by : Z. Jeffrey Chen

Download or read book Polyploid and Hybrid Genomics written by Z. Jeffrey Chen and published by John Wiley & Sons. This book was released on 2013-04-05 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyploidy plays an important role in biological diversity, trait improvement, and plant species survival. Understanding the evolutionary phenomenon of polyploidy is a key challenge for plant and crop scientists. This book is made up of contributions from leading researchers in the field from around the world, providing a truly global review of the subject. Providing broad-ranging coverage, and up-to-date information from some of the world’s leading researchers, this book is an invaluable resource for geneticists, plant and crop scientists, and evolutionary biologists.

Cotton Research

Download Cotton Research PDF Online Free

Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535127365
Total Pages : 312 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!


Book Synopsis Cotton Research by : Ibrokhim Y. Abdurakhmonov

Download or read book Cotton Research written by Ibrokhim Y. Abdurakhmonov and published by BoD – Books on Demand. This book was released on 2016-11-09 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton is the most important natural fiber crop of our planet, which provides humanity with cloth and vegetable oil, medicinal compounds, meal and hull for livestock feed, energy sources, organic matter to enrich soil, and industrial lubricants. Therefore, cotton research to improve sustainable cotton production worldwide is the vital task of scientific community to address the increasing demands and needs for cotton products. This Cotton Research book presents readers updated information and advances in current cotton science investigations. Chapters of this book provide the latest developments on cotton research and cover topics on cotton research infrastructure, physiology and agronomy, breeding and genetics, modern biotechnology, genomics and molecular breeding, crop management, and cotton-based product and textile researches.

Plant Genomes: Methods for Genetic and Physical Mapping

Download Plant Genomes: Methods for Genetic and Physical Mapping PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401124426
Total Pages : 233 pages
Book Rating : 4.4/5 (11 download)

DOWNLOAD NOW!


Book Synopsis Plant Genomes: Methods for Genetic and Physical Mapping by : J.S. Beckmann

Download or read book Plant Genomes: Methods for Genetic and Physical Mapping written by J.S. Beckmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: JACQUES S. BECKMANN & THOMAS C. OSBORN Extraordinary progress has been made in the analyses of the genetic structures of higher eukaryotic genomes. Only ten years elapsed between the initial proposals to use molecular DNA markers for the generation of a complete linkage map of the human genome [5, 17] and the first description of a 10 centimorgan map of one of its chromosomes [22], soon to be followed by others. The availability of molecular DNA markers, henceforth called genomic markers [for a review of their properties see 1, 2, 20], represents a milestone in genetics by providing the capacity for complete genetic coverage of all genomes. It is important to remember that the nature of the DNA polymorphism or of the specific method used to uncover it can be quite different for different marker loci. The genetic variation detected can be a result of a simple point mutation, a DNA insertion/deletion event, or a change in repeat copy number at some hypervariable DNA [11] or micro satellite [21] motif. Currently, the methods of detection can involve use of restriction endonucleases, nucleic acid hybridization, or DNA sequence amplification. Each of these sources of var iation and methods of detection can have utility for different applications. Furthermore, new approaches for the detection of DNA polymorphism are constantly emerging. The primary concern here is that the monitored poly morphism defines a genetic marker 'useful' for the desired application.

Plant Genomes

Download Plant Genomes PDF Online Free

Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805584911
Total Pages : 155 pages
Book Rating : 4.8/5 (55 download)

DOWNLOAD NOW!


Book Synopsis Plant Genomes by : Jean-Nicolas Volff

Download or read book Plant Genomes written by Jean-Nicolas Volff and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on the evolutionary impact of polyploidization and transposable elements. Knowledge on the structure and evolution of plant sex chromosomes, centromeres and microRNAs is reviewed and updated. Taken together, the contributions by internationally recognized experts present a panoramic overview of the structural features and evolutionary dynamics of plant genomes.This volume of Genome Dynamics will provide researchers, teachers and students in the fields of biology and agronomy with a valuable source of current knowledge on plant genomes.

Cotton

Download Cotton PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471180456
Total Pages : 882 pages
Book Rating : 4.1/5 (84 download)

DOWNLOAD NOW!


Book Synopsis Cotton by : C. Wayne Smith

Download or read book Cotton written by C. Wayne Smith and published by John Wiley & Sons. This book was released on 1999-08-30 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a vital new source of "need-to-know" information for cotton industry professionals. Unlike other references that focus solely on growing the crop, this book also emphasizes the cotton industry as a whole, and includes material on the nature of cotton fibers and their processing; cotton standards and classification; and marketing strategies.

Genome Mapping in Plants

Download Genome Mapping in Plants PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Genome Mapping in Plants by : Andrew H. Paterson

Download or read book Genome Mapping in Plants written by Andrew H. Paterson and published by . This book was released on 1996 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Plant Genetics and Breeding

Download Principles of Plant Genetics and Breeding PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119626323
Total Pages : 855 pages
Book Rating : 4.1/5 (196 download)

DOWNLOAD NOW!


Book Synopsis Principles of Plant Genetics and Breeding by : George Acquaah

Download or read book Principles of Plant Genetics and Breeding written by George Acquaah and published by John Wiley & Sons. This book was released on 2020-12-14 with total page 855 pages. Available in PDF, EPUB and Kindle. Book excerpt: The revised edition of the bestselling textbook, covering both classical and molecular plant breeding Principles of Plant Genetics and Breeding integrates theory and practice to provide an insightful examination of the fundamental principles and advanced techniques of modern plant breeding. Combining both classical and molecular tools, this comprehensive textbook describes the multidisciplinary strategies used to produce new varieties of crops and plants, particularly in response to the increasing demands to of growing populations. Illustrated chapters cover a wide range of topics, including plant reproductive systems, germplasm for breeding, molecular breeding, the common objectives of plant breeders, marketing and societal issues, and more. Now in its third edition, this essential textbook contains extensively revised content that reflects recent advances and current practices. Substantial updates have been made to its molecular genetics and breeding sections, including discussions of new breeding techniques such as zinc finger nuclease, oligonucleotide directed mutagenesis, RNA-dependent DNA methylation, reverse breeding, genome editing, and others. A new table enables efficient comparison of an expanded list of molecular markers, including Allozyme, RFLPs, RAPD, SSR, ISSR, DAMD, AFLP, SNPs and ESTs. Also, new and updated “Industry Highlights” sections provide examples of the practical application of plant breeding methods to real-world problems. This new edition: Organizes topics to reflect the stages of an actual breeding project Incorporates the most recent technologies in the field, such as CRSPR genome edition and grafting on GM stock Includes numerous illustrations and end-of-chapter self-assessment questions, key references, suggested readings, and links to relevant websites Features a companion website containing additional artwork and instructor resources Principles of Plant Genetics and Breeding offers researchers and professionals an invaluable resource and remains the ideal textbook for advanced undergraduates and graduates in plant science, particularly those studying plant breeding, biotechnology, and genetics.

Transgenic Cotton

Download Transgenic Cotton PDF Online Free

Author :
Publisher : Humana Press
ISBN 13 : 9781627032117
Total Pages : 0 pages
Book Rating : 4.0/5 (321 download)

DOWNLOAD NOW!


Book Synopsis Transgenic Cotton by : Baohong Zhang

Download or read book Transgenic Cotton written by Baohong Zhang and published by Humana Press. This book was released on 2012-11-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cotton is the most important textile and cash crop and is widely cultivated in more than 70 countries, including the United States, China, and India. Because its long life cycle and complicated genetic background, it is hard to improve cotton using traditional breeding techniques although it has made much progress in the last several decades. Currently, transgenic techniques have become a powerful tool to improve cotton and transgenic cotton is among the first commercially genetically modified crops. Transgenic Cotton: Methods and Protocols provides a comprehensive collection of methods for creating and monitoring transgenic cotton and its application on agricultural and basic research. Divided into five convenient sections, topics covered include the current status and perspectives of transgenic cotton, the principle and methods for making transgenic cotton, the methods for detecting foreign gene copy and expression in transgenic plants, the improvement of cotton using transgenic technology, and finally the methods for monitoring the potential impact of transgenic cotton on environment, including gene flow. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Transgenic Cotton: Methods and Protocols will serve as an excellent resource for scientists as well as graduate students who work on transgenic plants, plant genetics, molecular biology and agricultural sciences.

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Download Scientific Frontiers in Developmental Toxicology and Risk Assessment PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Scientific Frontiers in Developmental Toxicology and Risk Assessment by : National Research Council

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.