Genetic Variation And Environmental Factors In Biological And Arterial Ageing

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Genetic Variation and Environmental Factors in Biological and Arterial Ageing

Author : Tim Nawrot
Publisher : Leuven University Press
ISBN 13 : 9789058674609
Total Pages : 168 pages
Book Rating : 4.6/5 (746 download)

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Book Synopsis Genetic Variation and Environmental Factors in Biological and Arterial Ageing by : Tim Nawrot

Download or read book Genetic Variation and Environmental Factors in Biological and Arterial Ageing written by Tim Nawrot and published by Leuven University Press. This book was released on 2005 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ageing, the decline in survival and bodily functions, caused by damage to macromolecules and tissues is intrinsically linked to life. Although universal and unavoidable, ageing does not occur in a uniform way. In the general population, it is actually a continuously distributed phenotype, in which genetic as well as environmental factors play an interactive role and explain the large interindividual differences between biological and chronological age. Cardiovascular disorders, which find there origins in deterioration of the structure and function of the large arteries, explain a large part of morbidity and mortality in industrialized societies. In this doctoral dissertation, the focus was on telomere length and arterial stiffness as biomarkers of biological and arterial ageing, respectively. It was investigated to what extent genetic and environmental determinants of oxidative stress and inflammation impact on the ageing process. Contents include: Introduction, Arterial ageing in cardiovascular risk prediction, Genetic and environmental factors in biological and arterial ageing, Telomere length and possible link to X chromosome, Role of smoking, oxidative stress and the -174 G/C interleukin-6 polymorphism in biological and vascular ageing, Environmental factors in arterial ageing, Blood pressure and blood selenium: a cross-sectional and a longitudinal population study, Endothelial function and outdoor temperature, General Discussion, Summary, Short Curriculum Vitae.

Early Vascular Aging (EVA)

Author : Pedro Guimarães Cunha
Publisher : Elsevier
ISBN 13 : 0443155135
Total Pages : 772 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Early Vascular Aging (EVA) by : Pedro Guimarães Cunha

Download or read book Early Vascular Aging (EVA) written by Pedro Guimarães Cunha and published by Elsevier. This book was released on 2024-02-29 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations

Genes, Behavior, and the Social Environment

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309101964
Total Pages : 385 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genes, Behavior, and the Social Environment by : Institute of Medicine

Download or read book Genes, Behavior, and the Social Environment written by Institute of Medicine and published by National Academies Press. This book was released on 2006-12-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.

Obesity and Cardiovascular Disease

Author : Malcolm K Robinson
Publisher : CRC Press
ISBN 13 : 1420018906
Total Pages : 475 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Obesity and Cardiovascular Disease by : Malcolm K Robinson

Download or read book Obesity and Cardiovascular Disease written by Malcolm K Robinson and published by CRC Press. This book was released on 2006-03-07 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although cardiovascular disease remains the leading proximate cause of death in the United States, it is now estimated that obesity may be equivalent to smoking as the leading cause of preventable death in America. In light of these statistics, this reference presents our current understanding of the epidemiology, pathology, and genetics of the obe

Cognitive Neuroscience of Aging

Author : Roberto Cabeza
Publisher : Oxford University Press
ISBN 13 : 0199372934
Total Pages : 633 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Cognitive Neuroscience of Aging by : Roberto Cabeza

Download or read book Cognitive Neuroscience of Aging written by Roberto Cabeza and published by Oxford University Press. This book was released on 2017 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rapidly growing body of research has consituted a new discipline that may be called cognitive neuroscience of aging. This book offers an introduction to the topic, useful to both professionals & students in cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology & neurology.

Genetics of Hypertension

Author : Anna F. Dominiczak
Publisher : Elsevier Health Sciences
ISBN 13 : 0444514562
Total Pages : 284 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Genetics of Hypertension by : Anna F. Dominiczak

Download or read book Genetics of Hypertension written by Anna F. Dominiczak and published by Elsevier Health Sciences. This book was released on 2007-01-01 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classic and modern tools of genetics have been applied to hypertension research for some 20 years. This volume in the Handbook of Hypertension series aims to go beyond a simple summary of discoveries and provides a critical commentary on many controversial issues. It will be particularly useful for clinician scientists at all stages of their careers, graduate students and post-doctoral scientists as well as all those interested in cardiovascular medicine and research throughout the entire spectrum from bench to bedside. As in every relatively young area of research, the initial excitement over the early positive observations has not always been confirmed by subsequent larger studies with greater statistical power. Issues related to current recommendations on design of studies and their analysis are therefore included. Pharmacogenetics and pharmacogenomics have been the subjects of many debates in recent years and are of particular importance in hypertension as life-long treatments, frequently with multiple drugs are given to millions of people world-wide. A critical appraisal of this controversial topic is provided. Several chapters on experimental genetics of hypertension with a special focus on physiological genomics are also included.

Biosocial Surveys

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309108675
Total Pages : 429 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biosocial Surveys by : National Research Council

Download or read book Biosocial Surveys written by National Research Council and published by National Academies Press. This book was released on 2008-01-06 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.

Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking

Author : Lishuang Cao
Publisher : Leuven University Press
ISBN 13 : 9789058675101
Total Pages : 140 pages
Book Rating : 4.6/5 (751 download)

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Book Synopsis Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking by : Lishuang Cao

Download or read book Modulation of CFTR and ENaC Channel Function by Interacting Proteins and Trafficking written by Lishuang Cao and published by Leuven University Press. This book was released on 2005 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models

Author : Kris Van Kuyck
Publisher : Leuven University Press
ISBN 13 : 9789058675545
Total Pages : 182 pages
Book Rating : 4.6/5 (755 download)

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Book Synopsis Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models by : Kris Van Kuyck

Download or read book Electrical Brain Stimulation in Psychiatric Disorders. Contributions from Research in Animal Models written by Kris Van Kuyck and published by Leuven University Press. This book was released on 2006 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Expression and Function of a Serotoninergic System in the Rat Anterior Pituitary

Author : Anna-Pia Papageorgiou
Publisher : Leuven University Press
ISBN 13 : 9789058675828
Total Pages : 166 pages
Book Rating : 4.6/5 (758 download)

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Book Synopsis Expression and Function of a Serotoninergic System in the Rat Anterior Pituitary by : Anna-Pia Papageorgiou

Download or read book Expression and Function of a Serotoninergic System in the Rat Anterior Pituitary written by Anna-Pia Papageorgiou and published by Leuven University Press. This book was released on 2006-12 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cells and Surveys

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309171431
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cells and Surveys by : National Research Council

Download or read book Cells and Surveys written by National Research Council and published by National Academies Press. This book was released on 2001-01-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: What can social science, and demography in particular, reasonably expect to learn from biological information? There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. Cells and Surveys addresses issues such as which biologic/genetic data should be collected in order to be most useful to a range of social scientists and whether amassing biological data has unintended side effects. The book also takes a look at the various ethical and legal concerns that such data collection entails.

12p Translocations in Acute Leukaemia

Author : Anniek Corveleyn
Publisher : Leuven University Press
ISBN 13 : 9789058674654
Total Pages : 138 pages
Book Rating : 4.6/5 (746 download)

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Book Synopsis 12p Translocations in Acute Leukaemia by : Anniek Corveleyn

Download or read book 12p Translocations in Acute Leukaemia written by Anniek Corveleyn and published by Leuven University Press. This book was released on 2005 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs

Author : Guy Eelen
Publisher : Leuven University Press
ISBN 13 : 9789058674753
Total Pages : 206 pages
Book Rating : 4.6/5 (747 download)

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Book Synopsis Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs by : Guy Eelen

Download or read book Molecular Modes of Action of 1[alpha], 25-dihydroxyvitamin D3 and Analogs written by Guy Eelen and published by Leuven University Press. This book was released on 2005 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Geriatric Gastroenterology

Author : C. S. Pitchumoni
Publisher : Springer Science & Business Media
ISBN 13 : 1441916237
Total Pages : 660 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Geriatric Gastroenterology by : C. S. Pitchumoni

Download or read book Geriatric Gastroenterology written by C. S. Pitchumoni and published by Springer Science & Business Media. This book was released on 2012-07-26 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.

Concepts of Epidemiology

Author : Raj S. Bhopal
Publisher : Oxford University Press
ISBN 13 : 0198739680
Total Pages : 481 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Concepts of Epidemiology by : Raj S. Bhopal

Download or read book Concepts of Epidemiology written by Raj S. Bhopal and published by Oxford University Press. This book was released on 2016 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: First edition published in 2002. Second edition published in 2008.

Stroke Genetics

Author : Hugh S. Markus
Publisher : Oxford Medical Publications
ISBN 13 : 0198515863
Total Pages : 362 pages
Book Rating : 4.1/5 (985 download)

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Book Synopsis Stroke Genetics by : Hugh S. Markus

Download or read book Stroke Genetics written by Hugh S. Markus and published by Oxford Medical Publications. This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

The Epidemiology of Aging

Author : Anne Newman
Publisher : Springer Science & Business Media
ISBN 13 : 9400750617
Total Pages : 611 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The Epidemiology of Aging by : Anne Newman

Download or read book The Epidemiology of Aging written by Anne Newman and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: The average age of the world’s population is increasing at an unprecedented rate and this increase is changing the world. This “Silver tsunami” emphasizes the need to provide advanced training in epidemiology and increase the cadre of experts in the study of aging. This book is designed to summarize unique methodological issues relevant to the study of aging, biomarkers of aging and the biology/physiology of aging and in-depth discussions of the etiology and epidemiology of common geriatric syndromes and diseases. Contributing authors in the book represent many disciplines, not only epidemiology and clinical geriatrics, but also demography, health services, research, cardiovascular disease, diabetes, psychiatry, neurology, social services, musculoskeletal diseases and cancer. The aim of the book is to provide a broad multidisciplinary background for any student/researcher interested in aging. The material in the book is organized and comprehensive. It represents the most up-to-date information on the scientific issues in aging research written by academics who specialize in research and training in the broad field of aging. The structure and organization of the book reflects our course series in the Epidemiology of Aging starting with the broad issues of demography and methodology, and then addressing specific health conditions and geriatric conditions common to older persons.