Advanced Genetic Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1444313088
Total Pages : 256 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Advanced Genetic Analysis by : R. Scott Hawley

Download or read book Advanced Genetic Analysis written by R. Scott Hawley and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Genetic Analysis brings a state-of-the-art,exciting new approach to genetic analysis. Focusing on theunderlying principles of modern genetic analysis, this bookprovides the 'how' and 'why' of the essential analytical toolsneeded. The author's vibrant, accessible style provides an easyguide to difficult genetic concepts, from mutation and genefunction to gene mapping and chromosome segregation. Throughout, abalanced range of model organisms and timely examples are used toillustrate the theoretical basics. Basic principles - Focuses students attention on the 'how' and'why' of the essential analytical tools. Vibrant, accessible style provides an easy guide throughdifficult genetic concepts and techniques. Text boxes highlight key questions and timely examples. Boxes of key information in each chapter, chapter summaries andextensive references - prompt the student to synthesise andreinforce the chapter material. Special reference section addressing a range of model organismsto help provide a particularly relevant context for students'research interests.

Genetic Theory and Analysis

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Publisher : John Wiley & Sons
ISBN 13 : 1118086929
Total Pages : 309 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Genetic Theory and Analysis by : Danny E. Miller

Download or read book Genetic Theory and Analysis written by Danny E. Miller and published by John Wiley & Sons. This book was released on 2023-08-29 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: GENETIC THEORY AND ANALYSIS Understand and apply what drives change of characteristic genetic traits and heredity Genetics is the study of how traits are passed from parents to their offspring and how the variation in those traits affects the development and health of the organism. Investigating how these traits affect the organism involves a diverse set of approaches and tools, including genetic screens, DNA and RNA sequencing, mapping, and methods to understand the structure and function of proteins. Thus, there is a need for a textbook that provides a broad overview of these methods. Genetic Theory and Analysis meets this need by describing key approaches and methods in genetic analysis through a historical lens. Focusing on the five basic principles underlying the field—mutation, complementation, recombination, segregation, and regulation—it identifies the full suite of tests and methodologies available to the geneticist in an age of flourishing genetic and genomic research. This second edition of the text has been updated to reflect recent advances and increase accessibility to advanced undergraduate students. Genetic Theory and Analysis, 2nd edition readers will also find: Detailed treatment of subjects including mutagenesis, meiosis, complementation, suppression, and more Updated discussion of epistasis, mosaic analysis, RNAi, genome sequencing, and more Appendices discussing model organisms, genetic fine-structure analysis, and tetrad analysis Genetic Theory and Analysis is ideal for both graduate students and advanced undergraduates undertaking courses in genetics, genetic engineering, and computational biology.

Genetic Analysis

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Publisher : Oxford University Press
ISBN 13 : 0199681260
Total Pages : 580 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Genetic Analysis by : Philip Mark Meneely

Download or read book Genetic Analysis written by Philip Mark Meneely and published by Oxford University Press. This book was released on 2014 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight.

An Introduction to Statistical Genetic Data Analysis

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Publisher : MIT Press
ISBN 13 : 0262357445
Total Pages : 433 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis An Introduction to Statistical Genetic Data Analysis by : Melinda C. Mills

Download or read book An Introduction to Statistical Genetic Data Analysis written by Melinda C. Mills and published by MIT Press. This book was released on 2020-02-18 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

Genetic Data Analysis for Plant and Animal Breeding

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Publisher : Springer
ISBN 13 : 3319551779
Total Pages : 400 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Genetic Data Analysis for Plant and Animal Breeding by : Fikret Isik

Download or read book Genetic Data Analysis for Plant and Animal Breeding written by Fikret Isik and published by Springer. This book was released on 2017-09-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the gap between textbooks of quantitative genetic theory, and software manuals that provide details on analytical methods but little context or perspective on which methods may be most appropriate for a particular application. Accordingly this book is composed of two sections. The first section (Chapters 1 to 8) covers topics of classical phenotypic data analysis for prediction of breeding values in animal and plant breeding programs. In the second section (Chapters 9 to 13) we provide the concept and overall review of available tools for using DNA markers for predictions of genetic merits in breeding populations. With advances in DNA sequencing technologies, genomic data, especially single nucleotide polymorphism (SNP) markers, have become available for animal and plant breeding programs in recent years. Analysis of DNA markers for prediction of genetic merit is a relatively new and active research area. The algorithms and software to implement these algorithms are changing rapidly. This section represents state-of-the-art knowledge on the tools and technologies available for genetic analysis of plants and animals. However, readers should be aware that the methods or statistical packages covered here may not be available or they might be out of date in a few years. Ultimately the book is intended for professional breeders interested in utilizing these tools and approaches in their breeding programs. Lastly, we anticipate the usage of this volume for advanced level graduate courses in agricultural and breeding courses.

Genetic Analysis

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Publisher : Pearson Educacion
ISBN 13 : 9780321818461
Total Pages : 864 pages
Book Rating : 4.8/5 (184 download)

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Book Synopsis Genetic Analysis by : Mark F. Sanders

Download or read book Genetic Analysis written by Mark F. Sanders and published by Pearson Educacion. This book was released on 2011-12-14 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Informed by many years of genetics teaching and research experience, authors Mark Sanders and John Bowman use an integrative approach that helps contextualize three core challenges of learning genetics: solving problems, understanding evolution, and understanding the connection between traditional genetics models and more modern approaches. This package contains: Genetic Analysis: An Integrated Approach

Mathematical and Statistical Methods for Genetic Analysis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387217509
Total Pages : 376 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Mathematical and Statistical Methods for Genetic Analysis by : Kenneth Lange

Download or read book Mathematical and Statistical Methods for Genetic Analysis written by Kenneth Lange and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to equip students in the mathematical siences to understand and model the epidemiological and experimental data encountered in genetics research. This second edition expands the original edition by over 100 pages and includes new material. Sprinkled throughout the chapters are many new problems.

Analysis of Human Genetic Linkage

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Publisher : JHU Press
ISBN 13 : 9780801861406
Total Pages : 418 pages
Book Rating : 4.8/5 (614 download)

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Book Synopsis Analysis of Human Genetic Linkage by : Jurg Ott

Download or read book Analysis of Human Genetic Linkage written by Jurg Ott and published by JHU Press. This book was released on 1999-04-16 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and basic genetic principles; Genetic loci genetic polymorphisms; Aspects of statistical inference; Basics of linkage analysis; The informativeness of family data; Multipoint linkage analysis; Penetrance; Quantitative phenotypes; Numerical and computerized methods; Variability of the recombination fraction; Inconsistencies; Linkage analysis with mendelian disease loci; Nonparametric methods; Two-locus inheritance; Complex traits.

Genetic Techniques for Biological Research

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Publisher : John Wiley & Sons
ISBN 13 : 9780471899198
Total Pages : 264 pages
Book Rating : 4.8/5 (991 download)

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Book Synopsis Genetic Techniques for Biological Research by : Corinne A. Michels

Download or read book Genetic Techniques for Biological Research written by Corinne A. Michels and published by John Wiley & Sons. This book was released on 2002-06-10 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Analysis is an advanced textbook to teach the theory and practice of molecular genetic analysis to senior undergraduates and graduates studying genetics, molecular biology and cell biology. This book uses a case study approach, with the yeast Saccharomyces as the model genetic organism, to explain the theory and practice of molecular genetic analysis. It provides enough information so readers will be able to apply the approach to their own research project.

Genetic Programming Theory and Practice IX

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Publisher : Springer Science & Business Media
ISBN 13 : 1461417708
Total Pages : 288 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Genetic Programming Theory and Practice IX by : Rick Riolo

Download or read book Genetic Programming Theory and Practice IX written by Rick Riolo and published by Springer Science & Business Media. This book was released on 2011-11-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: These contributions, written by the foremost international researchers and practitioners of Genetic Programming (GP), explore the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. Topics include: modularity and scalability; evolvability; human-competitive results; the need for important high-impact GP-solvable problems;; the risks of search stagnation and of cutting off paths to solutions; the need for novelty; empowering GP search with expert knowledge; In addition, GP symbolic regression is thoroughly discussed, addressing such topics as guaranteed reproducibility of SR; validating SR results, measuring and controlling genotypic complexity; controlling phenotypic complexity; identifying, monitoring, and avoiding over-fitting; finding a comprehensive collection of SR benchmarks, comparing SR to machine learning. This text is for all GP explorers. Readers will discover large-scale, real-world applications of GP to a variety of problem domains via in-depth presentations of the latest and most significant results.

Weighted Network Analysis

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Publisher : Springer Science & Business Media
ISBN 13 : 144198819X
Total Pages : 433 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Weighted Network Analysis by : Steve Horvath

Download or read book Weighted Network Analysis written by Steve Horvath and published by Springer Science & Business Media. This book was released on 2011-04-30 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.

Primer of Genetic Analysis

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Publisher : Cambridge University Press
ISBN 13 : 1139465643
Total Pages : 488 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Primer of Genetic Analysis by : James N. Thompson, Jr

Download or read book Primer of Genetic Analysis written by James N. Thompson, Jr and published by Cambridge University Press. This book was released on 2007-10-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable student-tested study aid, this primer, first published in 2007, provides guided instruction for the analysis and interpretation of genetic principles and practice in problem solving. Each section is introduced with a summary of useful hints for problem solving and an overview of the topic with key terms. A series of problems, generally progressing from simple to more complex, then allows students to test their understanding of the material. Each question and answer is accompanied by detailed explanation. This third edition includes additional problems in basic areas that often challenge students, extended coverage in molecular biology and development, an expanded glossary of terms, and updated historical landmarks. Students at all levels, from beginning biologists and premedical students to graduates seeking a review of basic genetics, will find this book a valuable aid. It will complement the formal presentation in any genetics textbook or stand alone as a self-paced review manual.

Genetics and Analysis of Quantitative Traits

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Publisher : Sinauer Associates Incorporated
ISBN 13 : 9780878934812
Total Pages : 980 pages
Book Rating : 4.9/5 (348 download)

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Book Synopsis Genetics and Analysis of Quantitative Traits by : Michael Lynch

Download or read book Genetics and Analysis of Quantitative Traits written by Michael Lynch and published by Sinauer Associates Incorporated. This book was released on 1998-01 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Genetic Theory for Cubic Graphs

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Publisher : Springer
ISBN 13 : 3319196804
Total Pages : 118 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Genetic Theory for Cubic Graphs by : Pouya Baniasadi

Download or read book Genetic Theory for Cubic Graphs written by Pouya Baniasadi and published by Springer. This book was released on 2015-07-15 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was motivated by the notion that some of the underlying difficulty in challenging instances of graph-based problems (e.g., the Traveling Salesman Problem) may be “inherited” from simpler graphs which – in an appropriate sense – could be seen as “ancestors” of the given graph instance. The authors propose a partitioning of the set of unlabeled, connected cubic graphs into two disjoint subsets named genes and descendants, where the cardinality of the descendants dominates that of the genes. The key distinction between the two subsets is the presence of special edge cut sets, called cubic crackers, in the descendants. The book begins by proving that any given descendant may be constructed by starting from a finite set of genes and introducing the required cubic crackers through the use of six special operations, called breeding operations. It shows that each breeding operation is invertible, and these inverse operations are examined. It is therefore possible, for any given descendant, to identify a family of genes that could be used to generate the descendant. The authors refer to such a family of genes as a “complete family of ancestor genes” for that particular descendant. The book proves the fundamental, although quite unexpected, result that any given descendant has exactly one complete family of ancestor genes. This result indicates that the particular combination of breeding operations used strikes the right balance between ensuring that every descendant may be constructed while permitting only one generating set. The result that any descendant can be constructed from a unique set of ancestor genes indicates that most of the structure in the descendant has been, in some way, inherited from that, very special, complete family of ancestor genes, with the remaining structure induced by the breeding operations. After establishing this, the authors proceed to investigate a number of graph theoretic properties: Hamiltonicity, bipartiteness, and planarity, and prove results linking properties of the descendant to those of the ancestor genes. They develop necessary (and in some cases, sufficient) conditions for a descendant to contain a property in terms of the properties of its ancestor genes. These results motivate the development of parallelizable heuristics that first decompose a graph into ancestor genes, and then consider the genes individually. In particular, they provide such a heuristic for the Hamiltonian cycle problem. Additionally, a framework for constructing graphs with desired properties is developed, which shows how many (known) graphs that constitute counterexamples of conjectures could be easily found.

Evolution Of Life Histories

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Publisher : Springer Science & Business Media
ISBN 13 : 9780412023910
Total Pages : 554 pages
Book Rating : 4.0/5 (239 download)

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Book Synopsis Evolution Of Life Histories by : Derek Roff

Download or read book Evolution Of Life Histories written by Derek Roff and published by Springer Science & Business Media. This book was released on 1993-04-30 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many different types of organisms in the world: they differ in size, physiology, appearance, and life history. The challenge for evolutionary biology is to explain how such diversity arises. The Evolution of Life Histories does this by showing that natural selection is the principal underlying force molding life history variation. The book describes in particular the ways in which variation can be analyzed and predicted. It covers both the genetic and optimization approaches to life history analysis and gives an overview of the general framework of life history theory and the mathematical tools by which predictions can be made and tested. Factors affecting the age schedule of birth and death and the costs of reproduction are discussed. The Evolution of Life Histories concentrates on those theoretical developments that have been tested experimentally. It will interest both students and professionals in evolution, evolutionary ecology, mathematical and theoretical biology, and zoology and entomology.

Design, Analysis, and Interpretation of Genome-Wide Association Scans

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Publisher : Springer Science & Business Media
ISBN 13 : 1461494435
Total Pages : 344 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Design, Analysis, and Interpretation of Genome-Wide Association Scans by : Daniel O. Stram

Download or read book Design, Analysis, and Interpretation of Genome-Wide Association Scans written by Daniel O. Stram and published by Springer Science & Business Media. This book was released on 2013-11-23 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handling methods necessary to prepare data for statistical analysis. The goal in writing this book is to give statisticians, epidemiologists, and students in these fields the tools to design a powerful genome-wide study based on current technology. The other part of this is showing readers how to conduct analysis of the created study. Design and Analysis of Genome-Wide Association Studies provides a compendium of well-established statistical methods based upon single SNP associations. It also provides an introduction to more advanced statistical methods and issues. Knowing that technology, for instance large scale SNP arrays, is quickly changing, this text has significant lessons for future use with sequencing data. Emphasis on statistical concepts that apply to the problem of finding disease associations irrespective of the technology ensures its future applications. The author includes current bioinformatics tools while outlining the tools that will be required for use with extensive databases from future large scale sequencing projects. The author includes current bioinformatics tools while outlining additional issues and needs arising from the extensive databases from future large scale sequencing projects.

Genetic Analysis

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Publisher : Cambridge University Press
ISBN 13 : 0521884187
Total Pages : 331 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Genetic Analysis by : Raphael Falk

Download or read book Genetic Analysis written by Raphael Falk and published by Cambridge University Press. This book was released on 2009-05-14 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a paradox lying at the heart of the study of heredity. To understand the ways in which features are passed on down from one generation to the next, we have to dig deeper and deeper into the ultimate nature of things - from organisms, to genes, to molecules. And yet as we do this, increasingly we find we are out of focus with our subjects. What has any of this to do with the living, breathing organisms with which we started? Organisms are living. Molecules are not. How do we relate one to the other? In Genetic Analysis, one of the most important empirical scientists in the field in the twentieth century attempts, through a study of history and drawing on his own vast experience as a practitioner, to face this paradox head-on. His book offers a deep and innovative understanding of our ways of thinking about heredity.