Genetic Manipulation of Receptor Expression and Function

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Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 278 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetic Manipulation of Receptor Expression and Function by : Domenico Accili

Download or read book Genetic Manipulation of Receptor Expression and Function written by Domenico Accili and published by Wiley-Liss. This book was released on 2000-04-13 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our ability to manipulate the genome of living organisms for the elucidation of gene function in vivo has improved dramatically over the last decade. Genetic Manipulation of Receptor Expression and Function provides a comprehensive review of the principles and applications for genetic manipulation of receptor expression and function. By providing the necessary conceptual framework of transgenic and knockout technologies, Genetic Manipulation of Receptor Expression and Function offers a concise and easily accessible analysis for researchers. The material reviews the numerous advances in the field of transgenic technology allowing researchers to alter expression and function in the mouse genome. This volume also: * Provides a roadmap to transgenic and knockout methodology * Includes a detailed explanation of the differences between embryonic stem cells and fertilized zygotes * Clarifies the use of a DNA construct to make a transgenic mouse and a targeting vector for a knockout * Reviews the considerable progress in receptor research * Covers rapidly changing aspects in transgenic mouse technology (such as the generation of transgenic mice using large DNA fragments, the role of modifier genes, the importance of behavioral testing in analyzing disease phenotypes, and the growing role of antisense techniques in studies of gene function) Receptor biochemists, neuroscientists, molecular biologists, cell biologists, and molecular geneticists will find Genetic Manipulation of Receptor Expression and Function a useful guide.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Manipulation of the Nervous System

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Author :
Publisher : Elsevier
ISBN 13 : 9780080532400
Total Pages : 276 pages
Book Rating : 4.5/5 (324 download)

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Book Synopsis Genetic Manipulation of the Nervous System by :

Download or read book Genetic Manipulation of the Nervous System written by and published by Elsevier. This book was released on 1995-11-24 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences. Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas. The recent development of Gene Therapy procedures which allow specific genes to be delivered to human patients who lack functional copies of them is of major therapeutic importance. In addition such gene delivery methods can be used in other organisms to define the function of particular genes. These studies are of particular interest in the nervous system where there are many incurable diseases like Alzheimer's and Parkinson's diseases which may benefit from therapies of this kind. Unfortunately gene delivery methods for use in the nervous system have lagged behind those in other systems due to the fact that the methods developed in other systems are often not applicable to cells like neurons which do not divide. This book discusses a wide range of methods which have now been developed to overcome these problems and allow safe and efficient delivery of particular genes to the brain. Methods discussed include virological methods, physical methods (such as liposomes) and the transplantation of genetically modified cells. In a single volume therefore this book provides a complete view of these methods and indicates how they can be applied to the development of therapies for treating previously incurable neurological disorders.

Principles of Gene Manipulation and Genomics

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Publisher : John Wiley & Sons
ISBN 13 : 1405135441
Total Pages : 675 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Principles of Gene Manipulation and Genomics by : Sandy B. Primrose

Download or read book Principles of Gene Manipulation and Genomics written by Sandy B. Primrose and published by John Wiley & Sons. This book was released on 2006-02-10 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.

New Directions for Biosciences Research in Agriculture

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Publisher : National Academies Press
ISBN 13 : 0309035422
Total Pages : 136 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis New Directions for Biosciences Research in Agriculture by : National Research Council

Download or read book New Directions for Biosciences Research in Agriculture written by National Research Council and published by National Academies Press. This book was released on 1985-01-01 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by an integrated committee of plant and animal scientists, this review of newer molecular genetic techniques and traditional research methods is presented as a compilation of high-reward opportunities for agricultural research. Directed to the Agricultural Research Service and the agricultural research community at large, the volume discusses biosciences research in genetic engineering, animal science, plant science, and plant diseases and insect pests. An optimal climate for productive research is discussed.

Safety of Genetically Engineered Foods

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Publisher : National Academies Press
ISBN 13 : 0309166152
Total Pages : 254 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Safety of Genetically Engineered Foods by : National Research Council

Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Genetic Manipulation of DNA and Protein

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Publisher : BoD – Books on Demand
ISBN 13 : 9535109944
Total Pages : 465 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Genetic Manipulation of DNA and Protein by : David Figurski

Download or read book Genetic Manipulation of DNA and Protein written by David Figurski and published by BoD – Books on Demand. This book was released on 2013-02-05 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This diverse collection of research articles is united by the enormous power of modern molecular genetics. Every author accomplished two objectives: (1) making the field and the research described accessible to a large audience and (2) explaining fully the genetic tools and approaches that were used in the research. One fact stands out - the importance of a genetic approach to addressing a problem. I encourage you to read several chapters. You will feel the excitement of the scientists, and you will learn about an area of research with which you may not be familiar. Perhaps most importantly, you will understand the genetic approaches; and you will appreciate their importance to the research.

Principles of Gene Manipulation

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Publisher : Wiley-Blackwell
ISBN 13 : 9780632059546
Total Pages : 390 pages
Book Rating : 4.0/5 (595 download)

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Book Synopsis Principles of Gene Manipulation by : Sandy B. Primrose

Download or read book Principles of Gene Manipulation written by Sandy B. Primrose and published by Wiley-Blackwell. This book was released on 2002-02-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its sixth edition, Principles of Gene Manipulation provides an excellent introduction to the area of genetic engineering of plants, animals and microbes for advanced level undergraduates, with a basic understanding of genetics. This classic textbook has been substantially updated and revised to reflect the rapid advances that have been made in the core technologies in the seven years since the last edition. Furthermore, to put these technologies into context, the final chapter has been structured into six themes: · nucleic acids as diagnostic tools · new drugs and new therapies for genetic diseases · combating infectious disease · protein engineering · metabolic engineering · modern plant breeding A website is now available to complement this text, at www.blackwellpublishing.com/primrose Sixth edition of an extremely popular textbook. A complete rewrite by a new author team. Emerging technologies replace obsolete procedures. A new chapter on genomics and proteomics.

Gene Expression and Manipulation in Aquatic Organisms

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Publisher : Cambridge University Press
ISBN 13 : 9780521570039
Total Pages : 232 pages
Book Rating : 4.5/5 (7 download)

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Book Synopsis Gene Expression and Manipulation in Aquatic Organisms by : S. J. Ennion

Download or read book Gene Expression and Manipulation in Aquatic Organisms written by S. J. Ennion and published by Cambridge University Press. This book was released on 1996-06-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The techniques of molecular biology offer a powerful means of investigating and controlling the genetic basis of mechanisms operating in living organisms. The development of these techniques in aquatic animals has now reached the stage where important questions relating to growth, development and adaptation to the environment can be addressed at the level of gene expression, and the introduction and expression of novel genes achieved. This volume presents some of the most exciting advances in this rapidly expanding area, with contributions on the evolution of adaptation to low temperature, adaptation to short-term fluctuations in temperature and salinity, gene expression during growth and development, myosin polymorphism and the generation of transgenic fish. As such, it will be of interest to all those working in the fields of marine and freshwater biology and also to those working in aquaculture.

Gene Manipulation and Expression

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401165653
Total Pages : 567 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Gene Manipulation and Expression by : Robert E. Glass

Download or read book Gene Manipulation and Expression written by Robert E. Glass and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents selected papers from the international symposium on "Gene Manipulation and Expression" held in the Bechyne Castle, in South Bohemia, Czechoslovakia, on September 3 to 7, 1984. The symposium was sponsored by Academician J. Riman, vicepresident of the Czechoslovak Academy of Sci ences and director of the Institute of Molecular Genetics of the Czechoslovak Academy of Sciences, and by corresponding member of the Czechoslovak Academy of Sciences Prof. V. Krumphanzl, president of the Czechoslovak Society for Microbiology and director of the Institute of Microbiology of the Czechoslovak Academy of Sciences, with Dr. K. Mikulik of the same Institute acting as chairman of the Organizing Committee. The book is divided into four parts entitled: (l) Rearrangement of prokaryotic genetic material and DNA cloning vectors; (2) DNA-Dependent RNA polymerase in prokaryotes: structure and function; (3) The role of cAMP in gene expression; (4) Translational control of gene expression. We wish to thank all participants who con tributed to this volume. We should also like to express our deep gratitude to Drs. I. Janda and J. Weiser, both of the Institute of Microbiology of the Czechoslovak Academy of Sciences, for their invaluable help in the editorial work and Mrs. J. Pistorova for patiently retyping all the manu scripts

Field Testing Genetically Modified Organisms

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Publisher : National Academies Press
ISBN 13 : 0309040760
Total Pages : 185 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Field Testing Genetically Modified Organisms by : National Research Council

Download or read book Field Testing Genetically Modified Organisms written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potential benefits from the use of genetically modified organismsâ€"such as bacteria that biodegrade environmental pollutantsâ€"are enormous. To minimize the risks of releasing such organisms into the environment, regulators are working to develop rational safeguards. This volume provides a comprehensive examination of the issues surrounding testing these organisms in the laboratory or the field and a practical framework for making decisions about organism release. Beginning with a discussion of classical versus molecular techniques for genetic alteration, the volume is divided into major sections for plants and microorganisms and covers the characteristics of altered organisms, past experience with releases, and such specific issues as whether plant introductions could promote weediness. The executive summary presents major conclusions and outlines the recommended decision-making framework.

Experimental Manipulation of Gene Expression

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Publisher : Academic Press
ISBN 13 : 1483273970
Total Pages : 330 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Experimental Manipulation of Gene Expression by : Masayori Inouye

Download or read book Experimental Manipulation of Gene Expression written by Masayori Inouye and published by Academic Press. This book was released on 2014-06-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.

Genetic Engineering of Plants

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Publisher : National Academies Press
ISBN 13 : 0309034345
Total Pages : 97 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Genetic Engineering of Plants by : National Research Council

Download or read book Genetic Engineering of Plants written by National Research Council and published by National Academies Press. This book was released on 1984-02-01 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book...is, in fact, a short text on the many practical problems...associated with translating the explosion in basic biotechnological research into the next Green Revolution," explains Economic Botany. The book is "a concise and accurate narrative, that also manages to be interesting and personal...a splendid little book." Biotechnology states, "Because of the clarity with which it is written, this thin volume makes a major contribution to improving public understanding of genetic engineering's potential for enlarging the world's food supply...and can be profitably read by practically anyone interested in application of molecular biology to improvement of productivity in agriculture."

Testicular Function: From Gene Expression to Genetic Manipulation

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 342 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Testicular Function: From Gene Expression to Genetic Manipulation by : Mario Stefanini

Download or read book Testicular Function: From Gene Expression to Genetic Manipulation written by Mario Stefanini and published by Springer. This book was released on 1998-03-19 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetically Engineered Crops

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Publisher : National Academies Press
ISBN 13 : 0309437385
Total Pages : 607 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Genetically Engineered Crops by : National Academies of Sciences, Engineering, and Medicine

Download or read book Genetically Engineered Crops written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-01-28 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

An Introduction to Genetic Engineering

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Publisher : Cambridge University Press
ISBN 13 : 9780521004718
Total Pages : 308 pages
Book Rating : 4.0/5 (47 download)

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Book Synopsis An Introduction to Genetic Engineering by : Desmond S. T. Nicholl

Download or read book An Introduction to Genetic Engineering written by Desmond S. T. Nicholl and published by Cambridge University Press. This book was released on 2002-02-07 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author presents a basic introduction to the world of genetic engineering. Copyright © Libri GmbH. All rights reserved.

Guide to Biochemistry

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Publisher : Butterworth-Heinemann
ISBN 13 : 148318367X
Total Pages : 268 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Guide to Biochemistry by : James C. Blackstock

Download or read book Guide to Biochemistry written by James C. Blackstock and published by Butterworth-Heinemann. This book was released on 2014-06-28 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guide to Biochemistry provides a comprehensive account of the essential aspects of biochemistry. This book discusses a variety of topics, including biological molecules, enzymes, amino acids, nucleic acids, and eukaryotic cellular organizations. Organized into 19 chapters, this book begins with an overview of the construction of macromolecules from building-block molecules. This text then discusses the strengths of some weak acids and bases and explains the interaction of acids and bases involving the transfer of a proton from an acid to a base. Other chapters consider the effectiveness of enzymes, which can be appreciated through the comparison of spontaneous chemical reactions and enzyme-catalyzed reactions. This book discusses as well structure and function of lipids. The final chapter deals with the importance and applications of gene cloning in the fundamental biological research, which lies in the preparation of DNA fragments containing a specific gene. This book is a valuable resource for biochemists and students.