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Author : Geoffrey Chern-Yee Tan
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (116 download)
Download or read book Genetic Dissection of Sex Differences in Human Brain and Behaviour written by Geoffrey Chern-Yee Tan and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G. C.-Y. Tan
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (829 download)
Download or read book Genetic Dissection of Sex Differences in Human Brain and Behaviour written by G. C.-Y. Tan and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of sex differences in the brain and behaviour is indisputable. It forms the basis for differences in risk across a range of neurological and psychiatric disorders, as well as gender roles within society. The classical approach to investigating sex differences primarily involves comparisons between males and females. While informative for characterizing the wide array of sexually dimorphic traits, straight comparisons are insufficient to elucidate specific molecular contributions due to the multiplicity of confounding factors. Discrete genetic polymorphisms can be used to investigate variance in these traits due to sex-related molecular factors independent of confounds of sex. This thesis applies candidate genetics to understand the specific contributions of molecular components of the sex hormone pathways to sexual dimorphism in brain structure, personality and cognition. A cohort of 384 individuals were recruited to undergo MRI brain scans, cognitive and personality testing. They also provided blood samples for candidate genotyping in polymorphisms in genes for the androgen receptor, oestrogen receptors, progesterone receptor and aromatase enzyme that converts testosterone to oestrogen. Voxel-based morphometry was used to characterise regional differences in brain volume accounted for by these polymorphisms and the relationship to sex differences in brain volume. Diffusion tensor imaging was then used to determine variation in white matter integrity and structural connectivity due to these polymorphisms. Sex differences in personality and cognition are further investigated in terms of correlations with the polymorphisms and brain structure. Finally an endophenotype approach was used to investigate differential risk for conditions such as Alzheimer's disease and depression between sexes through related brain and personality-based traits. The neural and molecular genetic mechanisms underlying this risk are inferred from correlations with brain-based measures and genotype. The strengths and weaknesses of this approach and the scientific implications of this work to gender research are discussed.
Author : Jill B. Becker
Publisher : Oxford University Press
ISBN 13 : 0198042558
Total Pages : 506 pages
Book Rating : 4.1/5 (98 download)
Download or read book Sex Differences in the Brain written by Jill B. Becker and published by Oxford University Press. This book was released on 2007-12-04 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the basic and clinical biomedical research community, there is increasing recognition that differences between males and females across the lifespan affect an individual's health, his/her development of disease, signs and symptoms of pathophysiology, and response to therapy. This book is intended as a resource for scientists, clinicians, and students of the nervous system and behavior- a trove of practical information about how to study sex differences in the brain as well as a discussion of what is already known on the topic.
Author : Lesley J. Rogers
Publisher : Columbia University Press
ISBN 13 : 9780231120111
Total Pages : 156 pages
Book Rating : 4.1/5 (21 download)
Download or read book Sexing the Brain written by Lesley J. Rogers and published by Columbia University Press. This book was released on 2001 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: How much of sexual diversity is the result of nature versus nurture? Prevailing theories today lean heavily toward nature. Now a leading researcher in neuroscience and animal behavior shows how, in recent history, scientific claims about sex and gender differences have reflected the culture of the time. Although the conviction that genetics can explain everything is now widespread, the author demonstrates the interaction of culture and environment in the formation of behavioral traits and so provides an important corrective to popular notions of reductionism. Starting with a summary of sex and gender studies, Rogers explains the error of sex biasing, especially the once-assumed inferiority of women. She then addresses several modern studies and investigations, some of which assert that sex and gender differences are the product of genetic inheritance and hormones. Rogers uses laboratory evidence from studies of animals that help illustrate the biologically fluid properties of sex and gender. Sexing the Brain addresses a variety of topical questions: Are there sex differences in how we think and feel? Is language processed in different parts of the brain in men and women? Do social influences have a stronger influence on sexual behavior than sex hormone levels? Rogers concludes that "our biology does not bind us to remain the same.... We have the ability to change, and the future of sex differences belongs to us."
Author : Barry Keverne
Publisher : Cambridge University Press
ISBN 13 : 1108416853
Total Pages : 233 pages
Book Rating : 4.1/5 (84 download)
Download or read book Beyond Sex Differences written by Barry Keverne and published by Cambridge University Press. This book was released on 2017-09-07 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the evolutionary lead taken by the matriline in providing the intergenerational co-adaptations required for successful pregnancy.
Author : Maria Teresa Ferretti
Publisher : Academic Press
ISBN 13 : 012819345X
Total Pages : 514 pages
Book Rating : 4.1/5 (281 download)
Download or read book Sex and Gender Differences in Alzheimer's Disease written by Maria Teresa Ferretti and published by Academic Press. This book was released on 2021-07-23 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews: "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspired Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309132975
Total Pages : 287 pages
Book Rating : 4.3/5 (91 download)
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Author : D.C. Rao
Publisher : Academic Press
ISBN 13 : 0080569110
Total Pages : 788 pages
Book Rating : 4.0/5 (85 download)
Download or read book Genetic Dissection of Complex Traits written by D.C. Rao and published by Academic Press. This book was released on 2008-04-23 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more
Author : Kevin J. Mitchell
Publisher : Princeton University Press
ISBN 13 : 0691204152
Total Pages : 305 pages
Book Rating : 4.6/5 (912 download)
Download or read book Innate written by Kevin J. Mitchell and published by Princeton University Press. This book was released on 2020-03-31 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What makes you the way you are--and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains. Deftly guiding us through important new research, including his own groundbreaking work, he explains how variations in the way our brains develop before birth strongly influence our psychology and behavior throughout our lives, shaping our personality, intelligence, sexuality, and even the way we perceive the world. We all share a genetic program for making a human brain, and the program for making a brain like yours is specifically encoded in your DNA. But, as Mitchell explains, the way that program plays out is affected by random processes of development that manifest uniquely in each person, even identical twins. The key insight of Innate is that the combination of these developmental and genetic variations creates innate differences in how our brains are wired--differences that impact all aspects of our psychology--and this insight promises to transform the way we see the interplay of nature and nurture. Innate also explores the genetic and neural underpinnings of disorders such as autism, schizophrenia, and epilepsy, and how our understanding of these conditions is being revolutionized. In addition, the book examines the social and ethical implications of these ideas and of new technologies that may soon offer the means to predict or manipulate human traits. Compelling and original, Innate will change the way you think about why and how we are who we are."--Provided by the publisher.
Author : Rebecca M. Jordan-Young
Publisher : Harvard University Press
ISBN 13 : 0674058798
Total Pages : 409 pages
Book Rating : 4.6/5 (74 download)
Download or read book Brain Storm written by Rebecca M. Jordan-Young and published by Harvard University Press. This book was released on 2011-01-07 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Female and male brains are different, thanks to hormones coursing through the brain before birth. That’s taught as fact in psychology textbooks, academic journals, and bestselling books. And these hardwired differences explain everything from sexual orientation to gender identity, to why there aren’t more women physicists or more stay-at-home dads. In this compelling book, Rebecca Jordan-Young takes on the evidence that sex differences are hardwired into the brain. Analyzing virtually all published research that supports the claims of “human brain organization theory,” Jordan-Young reveals how often these studies fail the standards of science. Even if careful researchers point out the limits of their own studies, other researchers and journalists can easily ignore them because brain organization theory just sounds so right. But if a series of methodological weaknesses, questionable assumptions, inconsistent definitions, and enormous gaps between ambiguous findings and grand conclusions have accumulated through the years, then science isn’t scientific at all. Elegantly written, this book argues passionately that the analysis of gender differences deserves far more rigorous, biologically sophisticated science. “The evidence for hormonal sex differentiation of the human brain better resembles a hodge-podge pile than a solid structure...Once we have cleared the rubble, we can begin to build newer, more scientific stories about human development.”
Author : Gina Rippon
Publisher : Vintage Books
ISBN 13 : 9781784706814
Total Pages : 0 pages
Book Rating : 4.7/5 (68 download)
Download or read book The Gendered Brain written by Gina Rippon and published by Vintage Books. This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Barbie or Lego? Reading maps or reading emotions? Do you have a female brain or a male brain? Or is that the wrong question? On a daily basis we face deeply ingrained beliefs that our sex determines our skills and preferences, from toys and colours to career choice and salaries. But what does this mean for our thoughts, decisions and behaviour? Using the latest cutting-edge neuroscience, Gina Rippon unpacks the stereotypes that bombard us from our earliest moments and shows how these messages mould our ideas of ourselves and even shape our brains. Rigorous, timely and liberating, The Gendered Brainhas huge repercussions for women and men, for parents and children, and for how we identify ourselves. 'Highly accessible... Revolutionary to a glorious degree' Observer
Author : Julia Simner
Publisher : Oxford University Press, USA
ISBN 13 : 0199603324
Total Pages : 1104 pages
Book Rating : 4.1/5 (996 download)
Download or read book Oxford Handbook of Synesthesia written by Julia Simner and published by Oxford University Press, USA. This book was released on 2013-12 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synesthesia is a fascinating phenomenon which has captured the imagination of scientists and artists alike. This title brings together a broad body of knowledge about this condition into one definitive state-of-the-art handbook.
Author : Wim E. Crusio
Publisher : Elsevier
ISBN 13 : 0080536867
Total Pages : 994 pages
Book Rating : 4.0/5 (85 download)
Download or read book Handbook of Molecular-Genetic Techniques for Brain and Behavior Research written by Wim E. Crusio and published by Elsevier. This book was released on 1999-10-18 with total page 994 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.
Author : Zachary Elliott
Publisher : Lulu.com
ISBN 13 : 1387380915
Total Pages : 72 pages
Book Rating : 4.3/5 (873 download)
Download or read book Sex Differences: A Land of Confusion written by Zachary Elliott and published by Lulu.com. This book was released on 2017-11-19 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's the 21st century, and we are still being told that there are no differences between men and women, and that any differences we think exist are simply the result of social constructs--to claim otherwise is considered sexist and misogynistic. Sociologists point to disparities in the workforce, claiming these inequalities are the result of a patriarchal society. Yet what if these disparities could be explained through men and women's own choices and inclinations? What if, instead of simply resulting from the patriarchy, sexism, or societal-imposed gender roles, these differences can be explained through a multitude of factors--a mix of complex and interconnected variables? A look at the current scientific literature on sex differences and their origins, this paper reviews data from the fields of biology, psychology, evolutionary behavioral science, neuroendocrinology, and neurology, showing the complicated and nuanced nature of average sex differences between males and females.
Author : Simon LeVay
Publisher : MIT Press
ISBN 13 : 9780262620932
Total Pages : 196 pages
Book Rating : 4.6/5 (29 download)
Download or read book The Sexual Brain written by Simon LeVay and published by MIT Press. This book was released on 1994-07-25 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with the same clarity, directness, and humor that have made Simon LeVay one of the most popular lecturers at Harvard Medical School and at the University of California, San Diego, The Sexual Brain examines the biological roots of human sexual behavior. It puts forward the compelling case that the diversity of human sexual feelings and behavior can best be understood in terms of the development, structure, and function of the brain circuits that produce them. Discarding all preconceptions about the motivation and purpose of sexuality, LeVay discusses the scientific evidence bearing on such questions as why we are sexual animals, what the brain mechanisms are that produce sexual behavior, how these mechanisms differ between men and women and how these differences develop, and finally, what determines a person's sexual orientation: genes, prenatal events, family environment, or early sexual experiences? The Sexual Brain is broad in scope, covering evolutionary theory, molecular genetics, endocrinology, brain structure and function, cognitive psychology, and development. It is unified by LeVay's thesis that human sexual behavior, in all its diversity, is rooted in biological mechanisms that can be explored by laboratory science. The book does not shy away from the complexities of the field, but it can be readily appreciated and enjoyed by anyone with an intelligent interest in sex.
Author : B.F Skinner
Publisher : Simon and Schuster
ISBN 13 : 1476716153
Total Pages : 484 pages
Book Rating : 4.4/5 (767 download)
Download or read book Science And Human Behavior written by B.F Skinner and published by Simon and Schuster. This book was released on 2012-12-18 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The psychology classic—a detailed study of scientific theories of human nature and the possible ways in which human behavior can be predicted and controlled—from one of the most influential behaviorists of the twentieth century and the author of Walden Two. “This is an important book, exceptionally well written, and logically consistent with the basic premise of the unitary nature of science. Many students of society and culture would take violent issue with most of the things that Skinner has to say, but even those who disagree most will find this a stimulating book.” —Samuel M. Strong, The American Journal of Sociology “This is a remarkable book—remarkable in that it presents a strong, consistent, and all but exhaustive case for a natural science of human behavior…It ought to be…valuable for those whose preferences lie with, as well as those whose preferences stand against, a behavioristic approach to human activity.” —Harry Prosch, Ethics
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309171431
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cells and Surveys written by National Research Council and published by National Academies Press. This book was released on 2001-01-19 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: What can social science, and demography in particular, reasonably expect to learn from biological information? There is increasing pressure for multipurpose household surveys to collect biological data along with the more familiar interviewer-respondent information. Given that recent technical developments have made it more feasible to collect biological information in non-clinical settings, those who fund, design, and analyze survey data need to think through the rationale and potential consequences. This is a concern that transcends national boundaries. Cells and Surveys addresses issues such as which biologic/genetic data should be collected in order to be most useful to a range of social scientists and whether amassing biological data has unintended side effects. The book also takes a look at the various ethical and legal concerns that such data collection entails.
