Handbook of Molecular-Genetic Techniques for Brain and Behavior Research

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Author :
Publisher : Elsevier
ISBN 13 : 9780080536866
Total Pages : 962 pages
Book Rating : 4.5/5 (368 download)

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Book Synopsis Handbook of Molecular-Genetic Techniques for Brain and Behavior Research by : Wim E. Crusio

Download or read book Handbook of Molecular-Genetic Techniques for Brain and Behavior Research written by Wim E. Crusio and published by Elsevier. This book was released on 1999-10-18 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

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Author :
Publisher : Academic Press
ISBN 13 : 0128041161
Total Pages : 710 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai

Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Methods in Genomic Neuroscience

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Publisher : CRC Press
ISBN 13 : 9780367455132
Total Pages : 360 pages
Book Rating : 4.4/5 (551 download)

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Book Synopsis Methods in Genomic Neuroscience by : Hemin R Chin

Download or read book Methods in Genomic Neuroscience written by Hemin R Chin and published by CRC Press. This book was released on 2019-12-18 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by researchers in the forefront of the field, this book provides a guide for applying powerful molecular genetic techniques to the study of neural and behavioral systems. It supplies a foundation by which data on gene expression and function may be used to develop new therapeutic strategies for brain diseases. The book covers tools and tec

Guide to Research Techniques in Neuroscience

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Publisher : Academic Press
ISBN 13 : 0323915612
Total Pages : 416 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Guide to Research Techniques in Neuroscience by : Matt Carter

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Handbook of Behavior Genetics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387767274
Total Pages : 557 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Handbook of Behavior Genetics by : Yong-Kyu Kim

Download or read book Handbook of Behavior Genetics written by Yong-Kyu Kim and published by Springer Science & Business Media. This book was released on 2009-03-25 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

Handbook of Psychology, Biological Psychology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 047126444X
Total Pages : 748 pages
Book Rating : 4.4/5 (712 download)

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Book Synopsis Handbook of Psychology, Biological Psychology by : Michela Gallagher

Download or read book Handbook of Psychology, Biological Psychology written by Michela Gallagher and published by John Wiley & Sons. This book was released on 2003-03-11 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes established theories and cutting-edge developments. Presents the work of an international group of experts. Presents the nature, origin, implications, an future course of major unresolved issues in the area.

Handbook of Stress and the Brain Part 1: The Neurobiology of Stress

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Publisher : Elsevier
ISBN 13 : 9780444511737
Total Pages : 864 pages
Book Rating : 4.5/5 (117 download)

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Book Synopsis Handbook of Stress and the Brain Part 1: The Neurobiology of Stress by : Thomas Steckler

Download or read book Handbook of Stress and the Brain Part 1: The Neurobiology of Stress written by Thomas Steckler and published by Elsevier. This book was released on 2005-03-24 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms

Handbook of Stress and the Brain Part 2: Stress: Integrative and Clinical Aspects

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Author :
Publisher : Elsevier
ISBN 13 : 0444518231
Total Pages : 485 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Handbook of Stress and the Brain Part 2: Stress: Integrative and Clinical Aspects by : Thomas Steckler

Download or read book Handbook of Stress and the Brain Part 2: Stress: Integrative and Clinical Aspects written by Thomas Steckler and published by Elsevier. This book was released on 2005-03-24 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 2 treats the complexity of short-term and long-term regulation of stress responsivity, the role of stress in psychiatric disorders as based on both preclinical and clinical evidence, and the current status with regard to new therapeutic strategies targetting stress-related disorders.

What's Wrong With My Mouse?

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Publisher : John Wiley & Sons
ISBN 13 : 0471471925
Total Pages : 540 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis What's Wrong With My Mouse? by : Jacqueline N. Crawley

Download or read book What's Wrong With My Mouse? written by Jacqueline N. Crawley and published by John Wiley & Sons. This book was released on 2007-03-23 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

Handbook of Microdialysis

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Author :
Publisher : Elsevier
ISBN 13 : 0080469663
Total Pages : 713 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Microdialysis by :

Download or read book Handbook of Microdialysis written by and published by Elsevier. This book was released on 2007-02-02 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience. * Presents microdialysis methods and interpretation including the technical aspects of microdialysis as a sampling technique followed by the analytical chemical methods* Discusses the role of microdialysis in pharmacology, drug development and models of CNS pathology* Includes clinical applications of microdialysis

Handbook of Anxiety and Fear

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Publisher : Elsevier
ISBN 13 : 0080559522
Total Pages : 535 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Anxiety and Fear by : D. Caroline Blanchard

Download or read book Handbook of Anxiety and Fear written by D. Caroline Blanchard and published by Elsevier. This book was released on 2011-09-02 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning in response to threat. These patterns are stringently selected, providing a close fit with environmental situations and events; they are highly conservative across mammalian species, producing important similarities, along with some systematic differences, in their human expression in comparison to that of nonhuman mammals. These patterns are described, with attention to both adaptive and maladaptive components, and related to new understanding of neuroanatomic, neurotransmitter, and genetic mechanisms. Although chapters in the volume acknowledge important differences in views of fear and anxiety stemming from animal vs. human research, the emphasis of the volume is on a search for an integrated view that will facilitate the use of animal models of anxiety to predict drug response in people; on new technologies that will enable direct evaluation of biological mechanisms in anxiety disorders; and on strengthening the analysis of anxiety disorders as biological phenomena. Integrates animal and human research on fear and anxiety Presents emerging and developing fields of human anxiety research including imaging of anxiety disorders, the genetics of anxiety, the pharmacology of anxiolysis, recent developments in classification of anxiety disorders, linking these to animal work Covers basic research on innate and conditioned responses to threat Presents work from the major laboratories, on fear learning and extinction Reviews research on an array of neurotransmitter and neuromodulator systems related to fear and anxiety Compares models, and neural systems for learned versus unlearned responses to threat Relates the findings to the study, diagnostics, and treatment of anxiety disorders, the major source of mental illness in modern society (26 % of Americans are affected by anxiety disorders!)

Handbook of Episodic Memory

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Publisher : Elsevier
ISBN 13 : 0080932363
Total Pages : 647 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Episodic Memory by : Ekrem Dere

Download or read book Handbook of Episodic Memory written by Ekrem Dere and published by Elsevier. This book was released on 2008-09-04 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: Episodic memory is the name of the kind of memory that records personal experiences instead of the mere remembering of impersonal facts and rules. This type of memory is extremely sensitive to ageing and disease so an understanding of the mechanisms of episodic memory might lead to the development of therapies suited to improve memory in some patient populations. Episodic memory is unique in that it includes an aspect of self-awareness and helps us to remember who we are in terms of what we did and what we have been passed through and what we should do in the future. This book brings together a renowned team of contributors from the fields of cognitive psychology, neuropsychology and behavioural and molecular neuroscience. It provides a detailed and comprehensive overview of recent developments in understanding human episodic memory and animal episodic-like memory in terms of concepts, methods, mechanisms, neurobiology and pathology. The work presented within this book will have a profound effect on the direction that future research in this topic will take. The first and most current comprehensive handbook on what we know about episodic memory, the memory of events, time, place, and emotion, and a key feature of awareness and consciousness Articles summarize our understanding of the mechanisms of episodic memory as well as surveying the neurobiology of epsidodic memory in patients, animal studies and functional imaging work Includes 34 heavily illustrated chapters in two sections by the leading scientists in the field

Handbook of Developmental Psychology

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Author :
Publisher : SAGE
ISBN 13 : 9780761962311
Total Pages : 718 pages
Book Rating : 4.9/5 (623 download)

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Book Synopsis Handbook of Developmental Psychology by : Jaan Valsiner

Download or read book Handbook of Developmental Psychology written by Jaan Valsiner and published by SAGE. This book was released on 2003-02-28 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive and authoritative this handbook pushes back the frontiers of the study of human development in one single volume. It makes an ideal reference for experienced individuals who wish to update their understanding and remain at the cutting edge of developmental psychology.

Valsiner: Handbook of Developmental (c) Psychology

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Publisher : SAGE
ISBN 13 : 9781446239902
Total Pages : 724 pages
Book Rating : 4.2/5 (399 download)

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Book Synopsis Valsiner: Handbook of Developmental (c) Psychology by : Jaan Valsiner Kevin J. Connolly

Download or read book Valsiner: Handbook of Developmental (c) Psychology written by Jaan Valsiner Kevin J. Connolly and published by SAGE. This book was released on with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: `This is an impressive work... and will provide the advanced reader with a rich source of theory and evidence. There is a huge amount to be got from the book and I suspect it will become a key work' - J Gavin Bremner, Department of Psychology, Lancaster University The Handbook of Developmental Psychology is a comprehensive, authoritative yet frontier-pushing overview of the study of human development presented in a single-volume format. It is ideal for experienced individuals wishing for an up-to-date survey of the central themes prevalent to developmental psychology, both past and present, and for those seeking a reference work to help appreciate the subject for the first time. The insightful contributions from world-leading developmental psychologists successfully and usefully integrate different perspectives to studying the subject, following a systematic life-span structure, from pre-natal development through to old age in human beings. The Handbook then concludes with a substantive section on the methodological approaches to the study of development, focusing on both qualitative and quantitative techniques. This unique reference work will be hugely influential for anyone needing or wishing for a broad, yet enriched understanding of this fascinating subject. It will be a particularly invaluable resource for academics and researchers in the fields of developmental psychology, education, parenting, cultural and biological psychology and anthropology.

Hormones, Brain and Behavior Online

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Publisher : Academic Press
ISBN 13 : 008088783X
Total Pages : 5944 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Hormones, Brain and Behavior Online by :

Download or read book Hormones, Brain and Behavior Online written by and published by Academic Press. This book was released on 2002-06-18 with total page 5944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. Comprehensive coverage of a growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research

Handbook of Psychology, Behavioral Neuroscience

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470890592
Total Pages : 786 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Handbook of Psychology, Behavioral Neuroscience by : Irving B. Weiner

Download or read book Handbook of Psychology, Behavioral Neuroscience written by Irving B. Weiner and published by John Wiley & Sons. This book was released on 2012-10-16 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychology is of interest to academics from many fields, as well as to the thousands of academic and clinical psychologists and general public who can't help but be interested in learning more about why humans think and behave as they do. This award-winning twelve-volume reference covers every aspect of the ever-fascinating discipline of psychology and represents the most current knowledge in the field. This ten-year revision now covers discoveries based in neuroscience, clinical psychology's new interest in evidence-based practice and mindfulness, and new findings in social, developmental, and forensic psychology.

Methods in Genomic Neuroscience

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Author :
Publisher : CRC Press
ISBN 13 : 1420038478
Total Pages : 344 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Methods in Genomic Neuroscience by : Hemin R. Chin

Download or read book Methods in Genomic Neuroscience written by Hemin R. Chin and published by CRC Press. This book was released on 2001-09-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed extraordinary advances in molecular genetic techniques and the accumulation of structural genomics information and resources in both human and model organisms. With the development of new technologies and the availability of resources like the sequence of eukaryotic genomes, problems of a previously unthinkable sco