Genetic Analysis

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An Introduction to Statistical Genetic Data Analysis

Author : Melinda C. Mills
Publisher : MIT Press
ISBN 13 : 0262357445
Total Pages : 433 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis An Introduction to Statistical Genetic Data Analysis by : Melinda C. Mills

Download or read book An Introduction to Statistical Genetic Data Analysis written by Melinda C. Mills and published by MIT Press. This book was released on 2020-02-18 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics. Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required. The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.

Primer of Genetic Analysis

Author : James N. Thompson, Jr
Publisher : Cambridge University Press
ISBN 13 : 1139465643
Total Pages : 488 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Primer of Genetic Analysis by : James N. Thompson, Jr

Download or read book Primer of Genetic Analysis written by James N. Thompson, Jr and published by Cambridge University Press. This book was released on 2007-10-01 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: An invaluable student-tested study aid, this primer, first published in 2007, provides guided instruction for the analysis and interpretation of genetic principles and practice in problem solving. Each section is introduced with a summary of useful hints for problem solving and an overview of the topic with key terms. A series of problems, generally progressing from simple to more complex, then allows students to test their understanding of the material. Each question and answer is accompanied by detailed explanation. This third edition includes additional problems in basic areas that often challenge students, extended coverage in molecular biology and development, an expanded glossary of terms, and updated historical landmarks. Students at all levels, from beginning biologists and premedical students to graduates seeking a review of basic genetics, will find this book a valuable aid. It will complement the formal presentation in any genetics textbook or stand alone as a self-paced review manual.

Solutions Manual for Introduction to Genetic Analysis

Author : Anthony Griffiths
Publisher : WH Freeman
ISBN 13 : 9781464187940
Total Pages : 0 pages
Book Rating : 4.1/5 (879 download)

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Book Synopsis Solutions Manual for Introduction to Genetic Analysis by : Anthony Griffiths

Download or read book Solutions Manual for Introduction to Genetic Analysis written by Anthony Griffiths and published by WH Freeman. This book was released on 2018-03-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the Solutions manual for Introduction to Genetic Analysis.

Genetic Analysis

Author : Mark F. Sanders
Publisher : Pearson Educacion
ISBN 13 : 9780321818461
Total Pages : 864 pages
Book Rating : 4.8/5 (184 download)

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Book Synopsis Genetic Analysis by : Mark F. Sanders

Download or read book Genetic Analysis written by Mark F. Sanders and published by Pearson Educacion. This book was released on 2011-12-14 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Informed by many years of genetics teaching and research experience, authors Mark Sanders and John Bowman use an integrative approach that helps contextualize three core challenges of learning genetics: solving problems, understanding evolution, and understanding the connection between traditional genetics models and more modern approaches. This package contains: Genetic Analysis: An Integrated Approach

Advanced Genetic Analysis

Author : R. Scott Hawley
Publisher : John Wiley & Sons
ISBN 13 : 1444313088
Total Pages : 256 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Advanced Genetic Analysis by : R. Scott Hawley

Download or read book Advanced Genetic Analysis written by R. Scott Hawley and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Genetic Analysis brings a state-of-the-art,exciting new approach to genetic analysis. Focusing on theunderlying principles of modern genetic analysis, this bookprovides the 'how' and 'why' of the essential analytical toolsneeded. The author's vibrant, accessible style provides an easyguide to difficult genetic concepts, from mutation and genefunction to gene mapping and chromosome segregation. Throughout, abalanced range of model organisms and timely examples are used toillustrate the theoretical basics. Basic principles - Focuses students attention on the 'how' and'why' of the essential analytical tools. Vibrant, accessible style provides an easy guide throughdifficult genetic concepts and techniques. Text boxes highlight key questions and timely examples. Boxes of key information in each chapter, chapter summaries andextensive references - prompt the student to synthesise andreinforce the chapter material. Special reference section addressing a range of model organismsto help provide a particularly relevant context for students'research interests.

Mathematical and Statistical Methods for Genetic Analysis

Author : Kenneth Lange
Publisher : Springer Science & Business Media
ISBN 13 : 0387217509
Total Pages : 376 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Mathematical and Statistical Methods for Genetic Analysis by : Kenneth Lange

Download or read book Mathematical and Statistical Methods for Genetic Analysis written by Kenneth Lange and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to equip students in the mathematical siences to understand and model the epidemiological and experimental data encountered in genetics research. This second edition expands the original edition by over 100 pages and includes new material. Sprinkled throughout the chapters are many new problems.

Genetic Analysis

Author : Philip Mark Meneely
Publisher : Oxford University Press
ISBN 13 : 0199681260
Total Pages : 580 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Genetic Analysis by : Philip Mark Meneely

Download or read book Genetic Analysis written by Philip Mark Meneely and published by Oxford University Press. This book was released on 2014 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight.

Genetic Data Analysis for Plant and Animal Breeding

Author : Fikret Isik
Publisher : Springer
ISBN 13 : 3319551779
Total Pages : 400 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Genetic Data Analysis for Plant and Animal Breeding by : Fikret Isik

Download or read book Genetic Data Analysis for Plant and Animal Breeding written by Fikret Isik and published by Springer. This book was released on 2017-09-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills the gap between textbooks of quantitative genetic theory, and software manuals that provide details on analytical methods but little context or perspective on which methods may be most appropriate for a particular application. Accordingly this book is composed of two sections. The first section (Chapters 1 to 8) covers topics of classical phenotypic data analysis for prediction of breeding values in animal and plant breeding programs. In the second section (Chapters 9 to 13) we provide the concept and overall review of available tools for using DNA markers for predictions of genetic merits in breeding populations. With advances in DNA sequencing technologies, genomic data, especially single nucleotide polymorphism (SNP) markers, have become available for animal and plant breeding programs in recent years. Analysis of DNA markers for prediction of genetic merit is a relatively new and active research area. The algorithms and software to implement these algorithms are changing rapidly. This section represents state-of-the-art knowledge on the tools and technologies available for genetic analysis of plants and animals. However, readers should be aware that the methods or statistical packages covered here may not be available or they might be out of date in a few years. Ultimately the book is intended for professional breeders interested in utilizing these tools and approaches in their breeding programs. Lastly, we anticipate the usage of this volume for advanced level graduate courses in agricultural and breeding courses.

Understanding Gene Testing

Author :
Publisher :
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Understanding Gene Testing by :

Download or read book Understanding Gene Testing written by and published by . This book was released on 1995 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Assessing Genetic Risks

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309047986
Total Pages : 353 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Assessing Genetic Risks by : Institute of Medicine

Download or read book Assessing Genetic Risks written by Institute of Medicine and published by National Academies Press. This book was released on 1994-01-01 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.

Analysis of Human Genetic Linkage

Author : Jurg Ott
Publisher : JHU Press
ISBN 13 : 9780801861406
Total Pages : 418 pages
Book Rating : 4.8/5 (614 download)

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Book Synopsis Analysis of Human Genetic Linkage by : Jurg Ott

Download or read book Analysis of Human Genetic Linkage written by Jurg Ott and published by JHU Press. This book was released on 1999-04-16 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction and basic genetic principles; Genetic loci genetic polymorphisms; Aspects of statistical inference; Basics of linkage analysis; The informativeness of family data; Multipoint linkage analysis; Penetrance; Quantitative phenotypes; Numerical and computerized methods; Variability of the recombination fraction; Inconsistencies; Linkage analysis with mendelian disease loci; Nonparametric methods; Two-locus inheritance; Complex traits.

Genetic Analysis of Complex Disease

Author : William K. Scott
Publisher : John Wiley & Sons
ISBN 13 : 1118123913
Total Pages : 340 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Genetic Analysis of Complex Disease by : William K. Scott

Download or read book Genetic Analysis of Complex Disease written by William K. Scott and published by John Wiley & Sons. This book was released on 2021-12-06 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Analysis of Complex Diseases An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies. This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues. Genetic Analysis of Complex Diseases also provides: A thorough introduction to study design for the identification of genes in complex traits Comprehensive explorations of basic concepts in genetics, disease phenotype definition and the determination of the genetic components of disease Practical discussions of modern bioinformatics tools for analysis of genetic data Reflecting on responsible conduct of research in genetic studies, as well as linkage analysis and data management New expanded chapter on complex genetic interactions This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.

An Evidence Framework for Genetic Testing

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309453291
Total Pages : 149 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis An Evidence Framework for Genetic Testing by : National Academies of Sciences, Engineering, and Medicine

Download or read book An Evidence Framework for Genetic Testing written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-21 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.

Genetics and Analysis of Quantitative Traits

Author : Michael Lynch
Publisher : Sinauer Associates Incorporated
ISBN 13 : 9780878934812
Total Pages : 980 pages
Book Rating : 4.9/5 (348 download)

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Book Synopsis Genetics and Analysis of Quantitative Traits by : Michael Lynch

Download or read book Genetics and Analysis of Quantitative Traits written by Michael Lynch and published by Sinauer Associates Incorporated. This book was released on 1998-01 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Wildlife DNA Analysis

Author : Adrian Linacre
Publisher : John Wiley & Sons
ISBN 13 : 1118496523
Total Pages : 360 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Wildlife DNA Analysis by : Adrian Linacre

Download or read book Wildlife DNA Analysis written by Adrian Linacre and published by John Wiley & Sons. This book was released on 2013-03-27 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly structured throughout, the introduction highlights the different types of crime where these techniques are regularly used. This chapter includes a discussion as to who performs forensic wildlife examinations, the standardisation and validation of methods, and the role of the expert witness in this type of alleged crime. This is followed by a detailed section on the science behind DNA typing including the problems in isolating DNA from trace material and subsequent genetic analysis are also covered. The book then undertakes a comprehensive review of species testing using DNA, including a step-by-step guide to sequence comparisons. A comparison of the different markers used in species testing highlights the criteria for a genetic marker. A full set of case histories illustrates the use of the different markers used. The book details the use of genetic markers to link two or more hairs/feather/leaves/needles to the same individual organism and the software used in population assignment. The problems and possibilities in isolating markers, along with the construction of allele databases are discussed in this chapter. The book concludes with evaluation and reporting of genetic evidence in wildlife forensic science illustrated by examples of witness statements.

Diagnostic Genetic Testing

Author : David Bourn
Publisher : Springer Nature
ISBN 13 : 3030855104
Total Pages : 145 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Diagnostic Genetic Testing by : David Bourn

Download or read book Diagnostic Genetic Testing written by David Bourn and published by Springer Nature. This book was released on 2021-11-13 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, technical advances have allowed genomic testing which provides a great opportunity for diagnosis but also an increased chance of uncertain or unexpected findings. This book addresses many of the questions that arise in this context and summarizes the essential concepts in diagnostic genetic testing in an easy-to-read manner. It also covers some broad context for the practical and ethical implications of examining human DNA sequences. The book starts with a general introduction to the field, providing enough background to allow readers without any previous education in genetics to comprehend the material in the subsequent chapters. The main part explores differing aspects of human genetics and the wider implications of testing in these areas. The author covers not only single gene inheritance, but also genetic testing of cancers and how testing benefits the patients. Special emphasis is also given to the questions of genetics and identity. The concluding part then draws the main themes together and summarises the wider significance of genetics. It also explores the gap between promises made for the impact of advances in genetics, and the actual benefits to patients. The book is written for everyone interested to learn about the process of genetic testing and the broader implications. Moreover, it is aimed at health professionals with an interest in genetics, at students or scientific trainees looking for an introduction to diagnostic genetics, and at professionals in health policy or health journalism.

Genetic Analyses of Wheat and Molecular Marker-Assisted Breeding, Volume 1

Author : Jichun Tian
Publisher : Springer
ISBN 13 : 9401773904
Total Pages : 528 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Genetic Analyses of Wheat and Molecular Marker-Assisted Breeding, Volume 1 by : Jichun Tian

Download or read book Genetic Analyses of Wheat and Molecular Marker-Assisted Breeding, Volume 1 written by Jichun Tian and published by Springer. This book was released on 2015-10-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book mainly describes the QTL mappings and efficacy analyses that are associated with wheat productivity, quality, physiology and various stress resistances and provides summaries of results from studies conducted both at home and abroad. It presents comparable data and analyses, helping readers to arrive at a more comprehensive understanding of the latest development in this field. The book provides a wealth of novel information, broad range of applications and in-depth findings on crop genetics and molecular breeding, making it valuable not only for plant breeders but also for academic faculties, senior researchers and advanced graduate students who are involved in plant breeding and genetics. Dr. Jichun Tian is a professor at the Department of Agronomy, Shandong Agricultural University, Tai’an, China.