Gating In Cerebral Networks

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Gating in Cerebral Networks

Author : Mircea Steriade
Publisher : Cambridge University Press
ISBN 13 : 1139462164
Total Pages : 79 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Gating in Cerebral Networks by : Mircea Steriade

Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by Cambridge University Press. This book was released on 2007-09-13 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The correct functioning of the mammalian brain depends on the integrated activity of myriad neuronal and non-neuronal cells. Discrete areas serve discrete functions, and dispersed or distributed communities of cells serve others. Throughout, these networks of activity are under the control of neuromodulatory systems. One goal of current neuroscientific research is to elucidate the precise methods by which these systems operate, especially during normal conscious behaviours and processes. Mircea Steriade and Denis Paré describe the neuronal properties and networks that exist within and between the cortex and two important sub-cortical structures: the thalamus and amygdala. The authors explore the changes in these properties, covering topics including morphology, electrophysiology, architecture and gating; and comparing regions and systems in both normal and diseased states. Aimed at graduates and postdoctoral researchers in neuroscience.

Gating in Cerebral Networks

Author : Mircea Steriade
Publisher : Cambridge University Press
ISBN 13 : 9780521851220
Total Pages : 342 pages
Book Rating : 4.8/5 (512 download)

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Book Synopsis Gating in Cerebral Networks by : Mircea Steriade

Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by Cambridge University Press. This book was released on 2007-09-13 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The correct functioning of the mammalian brain depends on the integrated activity of myriad neuronal and non-neuronal cells. Discrete areas serve discrete functions, and dispersed or distributed communities of cells serve others. Throughout, these networks of activity are under the control of neuromodulatory systems. One goal of current neuroscientific research is to elucidate the precise methods by which these systems operate, especially during normal conscious behaviours and processes. Mircea Steriade and Denis Paré describe the neuronal properties and networks that exist within and between the cortex and two important sub-cortical structures: the thalamus and amygdala. The authors explore the changes in these properties, covering topics including morphology, electrophysiology, architecture and gating; and comparing regions and systems in both normal and diseased states. Aimed at graduates and postdoctoral researchers in neuroscience.

Gating in Cerebral Networks

Author : Mircea Steriade
Publisher :
ISBN 13 : 9780511342349
Total Pages : 331 pages
Book Rating : 4.3/5 (423 download)

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Book Synopsis Gating in Cerebral Networks by : Mircea Steriade

Download or read book Gating in Cerebral Networks written by Mircea Steriade and published by . This book was released on 2007 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes how the many components of the mammalian brain interact under normal conditions and in diseased states.

Neurobiology of Sensation and Reward

Author : Jay A. Gottfried
Publisher : CRC Press
ISBN 13 : 142006729X
Total Pages : 458 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neurobiology of Sensation and Reward by : Jay A. Gottfried

Download or read book Neurobiology of Sensation and Reward written by Jay A. Gottfried and published by CRC Press. This book was released on 2011-03-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a

Cognitive Neuroscience of Attention

Author : Michael I. Posner
Publisher : Guilford Press
ISBN 13 : 9781593850487
Total Pages : 466 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Cognitive Neuroscience of Attention by : Michael I. Posner

Download or read book Cognitive Neuroscience of Attention written by Michael I. Posner and published by Guilford Press. This book was released on 2004-07-16 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the latest advances in understanding attention: its anatomy, circuitry, functions, and deficits. Outstanding investigators have written brief yet substantive chapters in which they not only summarize key findings but also illuminate their goals and the directions their research is taking. Coverage includes different cognitive models of attention; knowledge emerging from functional imaging and genetic studies; and neurophysiological, developmental, and neuropsychological approaches. Emerging knowledge is presented on processes that impair or alter attention, and clinical implications are discussed. Linking many levels of analysis, and featuring over 100 illustrations, the book moves us closer to a coherent view of the attentional system and the key role it plays in everyday life.

The Neurobiology of Schizophrenia

Author : Ted Abel
Publisher : Academic Press
ISBN 13 : 0128018771
Total Pages : 468 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Neurobiology of Schizophrenia by : Ted Abel

Download or read book The Neurobiology of Schizophrenia written by Ted Abel and published by Academic Press. This book was released on 2016-07-08 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Schizophrenia begins with an overview of the various facets and levels of schizophrenia pathophysiology, ranging systematically from its genetic basis over changes in neurochemistry and electrophysiology to a systemic neural circuits level. When possible, the editors point out connections between the various systems. The editors also depict methods and research strategies used in the respective field. The individual backgrounds of the two editors promote a synthesis between basic neuroscience and clinical relevance. Provides a comprehensive overview of neurobiological aspects of schizophrenia Discusses schizophrenia at behavioral, cognitive, clinical, electrophysiological, molecular, and genetic levels Edited by a translational researcher and a psychiatrist to promote synthesis between basic neuroscience and clinical relevance Elucidates connections between the various systems depicted, when possible

Animal and Translational Models for CNS Drug Discovery

Author : Robert A. McArthur
Publisher : Academic Press
ISBN 13 : 0080920411
Total Pages : 1367 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Animal and Translational Models for CNS Drug Discovery by : Robert A. McArthur

Download or read book Animal and Translational Models for CNS Drug Discovery written by Robert A. McArthur and published by Academic Press. This book was released on 2008-11-27 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.

Fundamentals of Brain Network Analysis

Author : Alex Fornito
Publisher : Academic Press
ISBN 13 : 0124081185
Total Pages : 494 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Fundamentals of Brain Network Analysis by : Alex Fornito

Download or read book Fundamentals of Brain Network Analysis written by Alex Fornito and published by Academic Press. This book was released on 2016-03-04 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse areas of neuroscience, ranging from the analysis of synaptic networks in the nematode worm to the characterization of large-scale human brain networks constructed with magnetic resonance imaging. This text is ideally suited to neuroscientists wanting to develop expertise in the rapidly developing field of neural connectomics, and to physical and computational scientists wanting to understand how these quantitative methods can be used to understand brain organization. Extensively illustrated throughout by graphical representations of key mathematical concepts and their practical applications to analyses of nervous systems Comprehensively covers graph theoretical analyses of structural and functional brain networks, from microscopic to macroscopic scales, using examples based on a wide variety of experimental methods in neuroscience Designed to inform and empower scientists at all levels of experience, and from any specialist background, wanting to use modern methods of network science to understand the organization of the brain

Connectivity and Functional Specialization in the Brain

Author : Thomas Heinbockel
Publisher : BoD – Books on Demand
ISBN 13 : 1839627964
Total Pages : 176 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Connectivity and Functional Specialization in the Brain by : Thomas Heinbockel

Download or read book Connectivity and Functional Specialization in the Brain written by Thomas Heinbockel and published by BoD – Books on Demand. This book was released on 2021-06-02 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘Connectivity and Functional Specialization in the Brain’ is a topic that describes nerve cells in terms of their anatomical and functional connections. The term connectome refers to a comprehensive map of neural connections, like a wiring diagram of an organism’s nervous system. Connectomics, the study of connectomes, can be applied to individual neurons and their synaptic connections, as well as to connections between neuronal populations or to functional and structural connectivity of different brain regions. This book addresses neural connectivity at these various scales in health and disease. The chapters review novel findings related to neuroanatomy and cell biology, neurophysiology, neural plasticity, changes of connectivity in neurological disorders, and sensory system connectivity. The book provides the reader with an overview of the current state-of-the-art of research of neural connectivity and focuses on the most important evidence-based developments in this area. Individual chapters focus on recent advances in specific areas of neural connectivity and in different brain regions. All chapters represent recent contributions to the rapidly developing field of neural connectivity.

Corticonics

Author : M. Abeles
Publisher : Cambridge University Press
ISBN 13 : 9780521376174
Total Pages : 298 pages
Book Rating : 4.3/5 (761 download)

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Book Synopsis Corticonics by : M. Abeles

Download or read book Corticonics written by M. Abeles and published by Cambridge University Press. This book was released on 1991-02-22 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how the brain works is probably the greatest scientific and intellectual challenge of our generation. The cerebral cortex is the instrument by which we carry the most complex mental functions. Fortunately, there exists an immense body of knowledge concerning both cortical structure and the properties of single neurons in the cortex. With the advent of the supercomputer, there has been increased interest in neural network modeling. What is needed is a new approach to an understanding of the mammalian cerebral cortex that will provide a link between the physiological description and the computer model. This book meets that need by combining anatomy, physiology, and modeling to achieve a quantitative description of cortical function. The material is presented didactically, starting with descriptive anatomy and comprehensively examining all aspects of modeling. The book gradually leads the reader from the macroscopic cortical anatomy and standard electrophysiological properties of single neurons to neural network models and synfire chains. The most modern trends in neural network modeling are explored.

An Internet in Your Head

Author : Daniel Graham
Publisher : Columbia University Press
ISBN 13 : 0231551614
Total Pages : 428 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis An Internet in Your Head by : Daniel Graham

Download or read book An Internet in Your Head written by Daniel Graham and published by Columbia University Press. This book was released on 2021-05-04 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whether we realize it or not, we think of our brains as computers. In neuroscience, the metaphor of the brain as a computer has defined the field for much of the modern era. But as neuroscientists increasingly reevaluate their assumptions about how brains work, we need a new metaphor to help us ask better questions. The computational neuroscientist Daniel Graham offers an innovative paradigm for understanding the brain. He argues that the brain is not like a single computer—it is a communication system, like the internet. Both are networks whose power comes from their flexibility and reliability. The brain and the internet both must route signals throughout their systems, requiring protocols to direct messages from just about any point to any other. But we do not yet understand how the brain manages the dynamic flow of information across its entire network. The internet metaphor can help neuroscience unravel the brain’s routing mechanisms by focusing attention on shared design principles and communication strategies that emerge from parallel challenges. Highlighting similarities between brain connectivity and the architecture of the internet can open new avenues of research and help unlock the brain’s deepest secrets. An Internet in Your Head presents a clear-eyed and engaging tour of brain science as it stands today and where the new paradigm might take it next. It offers anyone with an interest in brains a transformative new way to conceptualize what goes on inside our heads.

Network Neuroscience

Author : Flavio Fröhlich
Publisher : Academic Press
ISBN 13 : 0128015861
Total Pages : 482 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Network Neuroscience by : Flavio Fröhlich

Download or read book Network Neuroscience written by Flavio Fröhlich and published by Academic Press. This book was released on 2016-09-20 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich (www.networkneuroscientist.org) wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab (www.frohlichlab.org) pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. Easy-to-read, comprehensive introduction to the emerging field of network neuroscience Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics

Neuropathology of Drug Addictions and Substance Misuse Volume 1

Author : Victor R. Preedy
Publisher : Academic Press
ISBN 13 : 0128003766
Total Pages : 1132 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuropathology of Drug Addictions and Substance Misuse Volume 1 by : Victor R. Preedy

Download or read book Neuropathology of Drug Addictions and Substance Misuse Volume 1 written by Victor R. Preedy and published by Academic Press. This book was released on 2016-03-07 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader’s knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body

The Brain and Behavior

Author : David L. Clark
Publisher : Cambridge University Press
ISBN 13 : 9780521840507
Total Pages : 290 pages
Book Rating : 4.8/5 (45 download)

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Book Synopsis The Brain and Behavior by : David L. Clark

Download or read book The Brain and Behavior written by David L. Clark and published by Cambridge University Press. This book was released on 2005-09-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.

The Hippocampus Book

Author : Per Andersen
Publisher : Oxford University Press
ISBN 13 : 9780195100273
Total Pages : 892 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

In Vivo Optical Imaging of Brain Function, Second Edition

Author : Ron D. Frostig
Publisher : CRC Press
ISBN 13 : 142007685X
Total Pages : 428 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis In Vivo Optical Imaging of Brain Function, Second Edition by : Ron D. Frostig

Download or read book In Vivo Optical Imaging of Brain Function, Second Edition written by Ron D. Frostig and published by CRC Press. This book was released on 2009-05-06 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.

Jasper's Basic Mechanisms of the Epilepsies

Author : Jeffrey L. Noebels
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey L. Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey L. Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.