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Gastroduodenal Disease And Helicobacter Pylori
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Book Synopsis Gastroduodenal Disease and Helicobacter pylori by : T. Ulf Westblom
Download or read book Gastroduodenal Disease and Helicobacter pylori written by T. Ulf Westblom and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: I am delighted to be able to write the foreword for this new book on Helicobacter pylori by three pioneers in the field, Vlf West blom, Steven Czinn and John Nedrud. Because of their long experience in both basic and clinical aspects of H. pylori, the editors have been able to produce a volume which is authoritative and up to date in the science of H. pylori, while still being concise and interesting for the practicing physician or H. pylori novice. To achieve this, they have collected a very distinguished group of authors from within the Vnited States and around the world. The chapters are sequenced in approximately the same order as developments in H. pylori science over the past 15 years. The first chapter on the discovery of H. pylori is by Cliodna McNulty, who was the first person to culture the organism in Europe. The epidemiology is then described followed by the main clinical as sociations, which are gastritis and dyspepsia, peptic ulcers, can cers and lymphoma. This naturally leads to discussion of the laboratory aspects of H. pylori, especially the microbiology, in cluding essential information on antibiotic resistance patterns. Next, virulence and pathogenicity of H. pylori are explained as defined in studies using animal models, then by discussion of the metabolism of the organism. Finally, the interaction of the bac terium with the host immune systems is dealt with, including the implications of these findings as they relate to the development of future vaccines.
Book Synopsis Helicobacter pylori and Gastroduodenal Pathology by : Jose M. Pajares
Download or read book Helicobacter pylori and Gastroduodenal Pathology written by Jose M. Pajares and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the rapidly evolving field of Helicobacter infection new data on pathogenetic and pathophysiological mechanism have appeared. New methods which will be more sensitive and specific in the diagnosis of the infection are being developed and in this proceedings the first attempt using PCR technology is published. From the clinical point of view, a challenging aspect that needs clarification, is the observation which suggests an appearance of a correlation between the presence of the bacteria and abdominal pain and other symptoms in children whereas in old age no such correlation is evident. The relationship of H. pylori and gastric cancer is studied with histopathological data and epidemiological approaches. On the treatment side schemes using short courses and new antibiotic combinations are being investigated and preliminary data are reported.
Book Synopsis Basic and Clinical Aspects of Helicobacter pylori Infection by : Giovanni Gasbarrini
Download or read book Basic and Clinical Aspects of Helicobacter pylori Infection written by Giovanni Gasbarrini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: A century ago the Italian pathologist Bizzozero described the relationships between spiral bacteria and the mammalian gastro intestinal tract. Since 1982, when Helicobacter pylori was discovered, gastroduodenal disease have been completely revised as a con sequence of the results of basic and clinical research in this field. Progress in understanding the pathogenesis of this bacterium has been made by studying H. pylori infection in animal models. More specific diagnostic tools have been developed using new molecular biology techniques. Future trends are directed towards preparing a specific H. pylori vaccine. A new classification for gastritis, the Sydney System, including H. pylori gastritis, was proposed in 1990. As concerns the clinical approach to peptic ulcer disease in the 1990's, the majority of authors agree on the importance of H. pylori eradication. Moreover, recent clinical studies suggest that H. pylori infection can be associated with other gastroduodenal diseases, such as non ulcer dyspepsia and gastric cancer. Multicenter trials to standardize serological methods and evaluate the efficacy of new antimicrobial therapy schedules are planned throughout different European countries. The fourth Workshop of the European Helicobacter Pylori Study Group was held in Bologna, Italy, in November 1991. Two years before Bologna University celebrated its ninth centennial, giving evidence of being the oldest University in the modern world. Thus the H. pylori story that has continued for more than a century has been discussed once again at the University with the oldest tradition in the world.
Book Synopsis Helicobacter pylori by : Nayoung Kim
Download or read book Helicobacter pylori written by Nayoung Kim and published by Springer. This book was released on 2016-06-16 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.
Book Synopsis Helicobacter pylori Research by : Steffen Backert
Download or read book Helicobacter pylori Research written by Steffen Backert and published by Springer. This book was released on 2016-05-09 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of this pathogen. Both basic science and clinical research with actual practical consequences are taken into account. The chapters target microbiology, epidemiology, genetics, biochemistry, interactions with the immune system, signal transduction, pathogenic mechanisms in the gastroduodenal mucosa, gastric disease development, and therapy including antibiotics or probiotics treatment as well as vaccination strategies. This book is an important reference not only for clinicians but also microbiologists. It provides in a single volume an up-to-date summary of our current knowledge of this microbe and the multiple ways in which it impacts upon public health in all parts of the world.
Book Synopsis Helicobacter Pylori Infection and Gastroduodenal Ulcer Disease by :
Download or read book Helicobacter Pylori Infection and Gastroduodenal Ulcer Disease written by and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: (Uncorrected OCR) ABSTRACT of thesis entitled: "Helicobacter pylori infection and gastroduodenal ulcer disease" submitted by Dr. Kent-Man CHU for the degree of Master of Surgery at The University of Hong Kong in September 2001 In the past, reduction of acid has been the primary goal in the medical or surgical treatment of ulcer disease. The discovery of Helicobacter pylori has revolutionised its management. Nowadays, it is important to define clearly the roles of eradication therapy and surgery for ulcer disease. A series of prospective studies were started in 1995. Rapid urease test We tested a locally made rapid urease test for the diagnosis of H. pylori infection in 2316 patients. The sensitivity (91.6%), specificity (98.3%), positive predictive value (97.4%), and negative predictive value (94.4%) were comparable to those of commercial kits. We concluded that the local preparation is a simple, rapid, cheap, and accurate test for H. pylori infection. Eradication of H. pylori infection We performed a single-centre prospective randomised trial on 1000 patients evaluating the use of omeprazole-based dual and triple therapy in the eradication of H. pylori. The trial confirmed a superior rate of eradication of H. pylori by a one week course of omeprazole, c1arithromycin, and metronidazole (intent-to-treat 92%; per protocol 95.2%) in comparison to a two weeks course of omeprazole and amoxicillin (intent-to-treat 73.6%; per protocol 74.8%) (p
Download or read book Helicobacter pylori written by R.H. Hunt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture. The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy. The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.
Book Synopsis Helicobacter Pylori in Peptic Ulcer Disease by : Marian E. Beratan
Download or read book Helicobacter Pylori in Peptic Ulcer Disease written by Marian E. Beratan and published by . This book was released on 1993 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Helicobacter pylori in Human Diseases by : Shigeru Kamiya
Download or read book Helicobacter pylori in Human Diseases written by Shigeru Kamiya and published by Springer Nature. This book was released on 2019-10-22 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.
Book Synopsis Helicobacter pylori Biology and Clinical Practice by : C. Stewart Goodwin
Download or read book Helicobacter pylori Biology and Clinical Practice written by C. Stewart Goodwin and published by CRC Press. This book was released on 2018-01-18 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helicobacter pylori: Biology and Clinical Practice is the first book to fully describe H. pylori and the pathogenesis of H. pylori infections. It delineates the genome of H. pylori, discusses the molecular biology of the unique urease enzyme, and examines the clinical application of these discoveries. The book describes the epidemiology of H. pylori and its relevance to gastric cancer, and it offers clear guidance to clinicians for the diagnosis and treatment of peptic ulcer and non-ulcer dyspepsia in adults and children. Vaccine principles and possibilities are presented for the first time. Edited by the leader of the microbiology team that achieved the first culture of H. pylori, and named the Helicobacter genus, this book is essential for bacteriologists, gastroenterologists, microbiologists, infectious disease specialists, and other researchers interested in H. pylori.
Book Synopsis Gastroduodenal disease and Helicobacter pylori by : T. U. Westblom
Download or read book Gastroduodenal disease and Helicobacter pylori written by T. U. Westblom and published by . This book was released on 1999 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Helicobacter pylori Infection by : T.C. Northfield
Download or read book Helicobacter pylori Infection written by T.C. Northfield and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now that Helicobacter pylori is generally accepted as a key aetiological agent in gastric cancer as well as the main agent in peptic ulcer, it can claim to be the most important new discovery in clinical gastroenterology of the last decade, and yet there is no up-to-date book available on the subject that is designed primarily for the clinical gastroenterologist. This book aims to fill that niche. It should also be of interest to the basic scientist, to those providing a clinical laboratory service (microbiologists and histopathologists), and to epidemiologists and others involved in clinical research.
Book Synopsis Helicobacter Pylori by : John Holton
Download or read book Helicobacter Pylori written by John Holton and published by Clinical Publishing. This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most common infections in the world, and while most of those colonised by H. pylori will remain symptom free, about 20% of them may develop serious gastroduodenal disease including peptic ulcers or gastric cancer. H. pylori is the only bacterium linked to the development of cancer and consequently it is an important focus of research. Moreover, H. pylori may be related to a wide range of extra-gastrointestinal disease such as coronary heart disease, stroke, migraine, rosaceae and gall bladder disease. And, although the incidence of H. pylori infection is falling in industrialized countries it remains an important pathogen globally and as the prevalence of antibiotic resistance increases, the eradication rate of the organism is falling with a consequent failure to cure the ulcer disease. Against this background, this new work sets out the pathology, clinical presentation and options for treatment of H. pylori infection. A reference not only for clinicians but also microbiologists, it provides in a single volume an uptodate summary of our current knowledge of this organism and the many ways in which it impacts upon public health in all parts of the world.
Book Synopsis Vascular Responses to Pathogens by : Felicity N.E. Gavins
Download or read book Vascular Responses to Pathogens written by Felicity N.E. Gavins and published by Academic Press. This book was released on 2015-10-31 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs
Book Synopsis Gastritis and Gastric Cancer by : Paola Tonino
Download or read book Gastritis and Gastric Cancer written by Paola Tonino and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.
Book Synopsis Contemporary Diagnosis and Management of H Pylori-associated Gastrointestinal Diseases by : Kathleen S. Graham
Download or read book Contemporary Diagnosis and Management of H Pylori-associated Gastrointestinal Diseases written by Kathleen S. Graham and published by Handbooks in Health Care. This book was released on 2002 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This pocket-size (4.25x7") handbook summarizes what is known about diagnosis and management of H pylori-associated gastrointestinal diseases, with chapters on epidemiology, the effect of H pylori infection on gastroduodenal physiology, associated diseases, diagnostic tests, therapy, pediatrics, and vaccines. Color photos and micro images are included. Kathleen Graham is affiliated with the Department of Pediatrics at Columbia University College of Physicians and Surgeons. David Graham is chief of the Gastroenterology Section at the VA Medical Center, and teaches medicine at Baylor College. Annotation copyrighted by Book News, Inc., Portland, OR.
Book Synopsis Helicobacter pylori, Gastritis and Peptic Ulcer by : Peter Malfertheiner
Download or read book Helicobacter pylori, Gastritis and Peptic Ulcer written by Peter Malfertheiner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Helieobaeter pylori has recently been recognized as a new genus according to specific taxonomic criteria; the "popular" name Campylobaeter pylori has been corrected by scientific progress. Following the discovery of the spiral microorgan ism in gastric mucosa by Marshall and Warren in 1982, it took only a few years for H. pylori to become established as a factor in the pathogenesis of gastritis and peptic ulcer disease. Interest in different aspects of H. pylori has grown continuously and has attracted scientists from various medical and biological disciplines such as gastroenterology, microbiology, pathology, immunology, and pharmacology. Indeed H. pylori provides an excellent model for interdisciplinary interaction and cooperation. To promote this concept of interdisciplinary research and exchange of knowledge, a European Campylobacter (Helicobacter) Pylori Study Group was founded in 1987 in Copenhagen. The second meeting of this expanding group was held from October 12-14,1989 in Ulm, FRG. The fact that more than 500 participants attended the conference and that 187 original contributions from all five continents were presented clearly confirmed that H. pylori has "scientifically infected" the whole world. Our understanding of the microbiological and pathogenetic aspects of H. pylori is continuously being challenged as new results follow swifthy from different research areas. This book includes an update and progress report on the various aspects of H. pylori presented and discussed in special workshops held during the meeting in Ulm.
