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Author : FRANCISCO J. MORÓN RODRÍGUEZ
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)
Download or read book Gastric Cytoprotection : Experimental and Clinical Studies written by FRANCISCO J. MORÓN RODRÍGUEZ and published by . This book was released on 1983 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel Hollander
Publisher : Springer Science & Business Media
ISBN 13 : 1468456970
Total Pages : 228 pages
Book Rating : 4.4/5 (684 download)
Download or read book Gastric Cytoprotection written by Daniel Hollander and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric secretions contain hydrogen ions at a concentration that is more than one million times higher than their intracellular concentration. This phenomenal gradient as well as the demonstrated ability of gastric juice to digest tissues has motivated clinicians and investigators alike to emphasize acid secretion and acid ablation in studying the pathogenesis and therapy of peptic ulcer disease. Conse quently, over the past 150 years, we have made considerable progress in under standing the mechanisms and regulation of acid secretion by the stomach. Not surprisingly, therapy for both peptic disease and mucosal injury has also been predominantly directed at either neutralizing acid or suppressing its production. During the past 10 years, attention has been focused on factors other than acid in the genesis and therapy of ulcer disease. Work done worldwide demon strated that acid hypersecretion is not a common event in peptic ulcer disease. Therefore, we began realizing that factors other than acid secretion may be important in the genesis of ulcer disease or in gastroduodenal mucosal damage. In addition, new physiological information has established that the gas troduodenal mucosa is normally protected by a complex series of events includ ing mucus and bicarbonate secretion, cell renewal, surface mucosal restitution, and preservation of the microvasculature and mucosal proliferative zone.
Author : L.P. Filaretova
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021849
Total Pages : 259 pages
Book Rating : 4.3/5 (18 download)
Download or read book Cell/Tissue Injury and Cytoprotection/Organoprotection in the Gastrointestinal Tract written by L.P. Filaretova and published by Karger Medical and Scientific Publishers. This book was released on 2012-06-22 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there have been significant advances both in understanding the mechanisms involved in gastrointestinal mucosal injury and protection, as well as in the development of successful strategies for prevention and treatment of gastrointestinal injury. Nevertheless, many people worldwide still suffer from gastrointestinal damage.This book contains contributions by an international panel of researchers in the form of up-to-date reviews on the mechanisms of gastrointestinal injury and protection. These are complemented by papers discussing how these new findings about cell/tissue injury and cytoprotection/organoprotection can be applied to the prevention and treatment of tissue damage in the gastrointestinal tract. Moreover, the publication includes a special chapter on Andre Robert, who has discovered the phenomenon of gastric cytoprotection.This publication will be of great interest for both basic and clinical researchers in gastroenterology and pharmacology, reviewing the advances made so far and pointing towards future developments.
Author :
Publisher :
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.:/5 ( download)
Download or read book DUECR written by and published by . This book was released on 1990 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gyula Mozsik
Publisher : BoD – Books on Demand
ISBN 13 : 9535122517
Total Pages : 368 pages
Book Rating : 4.5/5 (351 download)
Download or read book Membrane-bound Atp-dependent Energy Systems and the Gastrointestinal Mucosal Damage and Protection written by Gyula Mozsik and published by BoD – Books on Demand. This book was released on 2016-03-09 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book on Membrane-bound Atp-dependent Energy Systems and the Gastrointestinal Mucosal Damage and Protection deals with various aspects of peptic ulcer disease, like clinical pharmacology, nutrition, molecular biochemical pharmacology as well as clinical aspects, and especially with the evaluation of certain biochemical mechanisms in human gastric mucosa and in animal gastric tissues obtained from different ulcer models. This book can be useful to physiologists; biochemists; pharmacologists, particularly molecular and biochemical pharmacologists; internists; gastroenterologists; biologists; surgeons and pharmacists.
Author : Rodolfo Cheli
Publisher :
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.3/5 (91 download)
Download or read book Gastric Protection written by Rodolfo Cheli and published by . This book was released on 1988 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gyula Mózsik
Publisher : Springer Science & Business Media
ISBN 13 : 9401153922
Total Pages : 366 pages
Book Rating : 4.4/5 (11 download)
Download or read book Cell Injury and Protection in the Gastrointestinal Tract written by Gyula Mózsik and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific main programmes of these series of symposia changed from time to time following the international scientific trends. The main programmes of the First Symposium were: 1. Gastric and intestinal cytoprotection; 2. Hepatoprotection; 3. Pancreatic protection. For the second one: 1. Gastrointestinal mucosal 'cytoprotection'; 2. Liver 'cytoprotection'; 3. Pancreatic 'cytoprotection'; 4. Free radicals and scavangers; 5. Computer approach to cytoprotec tion. For the third one: 1. Basic, central, peripheral and cellular mechanisms of gastrointestinaol cytoprotection; 2. Esophagal protection; 3. Gastric protection; 4. Small intestinal injury and protection; 5. Large bowel injury and protection; 6. Liver injury and protection; 7. Pancreas injury and protection. The main scientific programmes of the Fourth International Symposium on 'Cell Injury and Protection in the Gastrointestinal Tract' are: 1. General mechanisms of gastrointestinal injury and protection; 2. Cell injury and protection in the stomach; 3. Cell injury and protection in the small intestine and in the large bowel; 4. Cell injury and protection in the liver and pancreas; 5. Cell injury and protection of the premalignant status and malignant diseases in the gastrointestinal tract. The presented papers are published in this book. The abstracts of this meeting were published in Digestive Diseases and Sciences, and we record appreciation of the Editor ofthatjoumal for their publication. Some of the papers published here have appeared in Inflammopharmacology 1996;4:331-398.
Author : Sandor Szabo
Publisher : CRC Press
ISBN 13 : 9780849362163
Total Pages : 494 pages
Book Rating : 4.3/5 (621 download)
Download or read book Ulcer Disease written by Sandor Szabo and published by CRC Press. This book was released on 1989-07-31 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest data on the pathogenesis of ulcer disease is presented in this text, with the emphasis that an understanding of the pathogenesis and etiology of ulcer diseases represents the most rational approach to pharmacology - the prevention and treatment of ulcer disease. Early and late biochemical and functional changes, morphologic stages of the injury and healing phases, as well as vascular factors in ulceration are highlighted. In addition, new pathogenetic elements on neuroendocrine and other endogenous modulators and circadian rhythms in ulcerogenesis are covered. The section on new pharmacology consists of several chapters presenting new animal models of gastric, small intestinal and colonic ulcers because in vivo models represent the basis to test and accurately detect new antiulcer drugs. A large series of chapters cover new drugs for ulcer prevention and treatment. This book is indispensible to investigators in basic and applied research, academic and industrial pharmacologists and clinicians in gastroenterology.
Author :
Publisher :
ISBN 13 :
Total Pages : 1764 pages
Book Rating : 4.3/5 (243 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1764 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paola Tonino
Publisher : BoD – Books on Demand
ISBN 13 : 9533073756
Total Pages : 312 pages
Book Rating : 4.5/5 (33 download)
Download or read book Gastritis and Gastric Cancer written by Paola Tonino and published by BoD – Books on Demand. This book was released on 2011-09-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.
Author : Sandor Szabo
Publisher : Springer Science & Business Media
ISBN 13 : 1461518679
Total Pages : 251 pages
Book Rating : 4.4/5 (615 download)
Download or read book Neuroendocrinology of Gastrointestinal Ulceration written by Sandor Szabo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a meeting held in Esterel, Quebec, Canada, September 13-15, 1989.
Author : K. D. Rainsford
Publisher : Springer Science & Business Media
ISBN 13 : 9401097755
Total Pages : 465 pages
Book Rating : 4.4/5 (1 download)
Download or read book Side-Effects of Anti-Inflammatory Drugs written by K. D. Rainsford and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John B. Lombardini
Publisher : Springer Science & Business Media
ISBN 13 : 146150077X
Total Pages : 574 pages
Book Rating : 4.4/5 (615 download)
Download or read book Taurine 5 written by John B. Lombardini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Taurine Symposium- "Taurine: Beginning the 21'' Century"- was held September 20-23, 2002, on the beautiful island of Kauai in Hawaii. The headquarters of the meeting was the Radisson Kauai Beach Resort. This international meeting was attending by approximately 80 individuals from 23 nations and 4 continents. Seventy-five papers were presented either as platform presentations or poster presentations. Taurine, first isolated from ox bile in 1827 by Tiedemann and Gmelin and named in 1838 by Demarcay, became of significant scientific interest in 1968 when the first extensive review article was published by Jacobsen and Smith. Interest in taurine grew exponentially after 1975 when the first taurine symposium was organized by Ryan Huxtable in Tucson, Arizona. Since that date, taurine symposia have been held approximately every two years held in various cities and resort areas around the world. Taurine investigators have had the privilege of attending these scientific meetings on three continents - Asia, Europe, and North America. Since the initial meeting in 1975, a central question addressed during many of the symposia has been: "What is physiological, pharmacological, nutritional, and pathological role of taurine?". Although taurine has been established as an important osmolyte, it appears to affect many other biological processes. However, the exact mechanism(s) by "which taurine acts" has not yet been definitively answered. In Kauai, the patticipants discussed many topics and asked many questions regarding the role and actions of taurine.
Author :
Publisher :
ISBN 13 :
Total Pages : 666 pages
Book Rating : 4.:/5 (45 download)
Download or read book Journal of Physiology and Pharmacology written by and published by . This book was released on 1992 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Daniel Hollander
Publisher : Springer Science & Business Media
ISBN 13 : 058532154X
Total Pages : 373 pages
Book Rating : 4.5/5 (853 download)
Download or read book Sucralfate written by Daniel Hollander and published by Springer Science & Business Media. This book was released on 2007-07-07 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discuss the history of sucralfate's development, mechanisms of action, clinical efficacy, and future directions for research. This volume will be of interest to scientists and clinicians working in gastroenterology and gastrointestinal physiology.
Author : Robert F. Maronde
Publisher : Springer Science & Business Media
ISBN 13 : 1461248647
Total Pages : 528 pages
Book Rating : 4.4/5 (612 download)
Download or read book Topics in Clinical Pharmacology and Therapeutics written by Robert F. Maronde and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions.
Author : Franz J. Hock
Publisher : Springer
ISBN 13 : 9783319053912
Total Pages : 0 pages
Book Rating : 4.0/5 (539 download)
Download or read book Drug Discovery and Evaluation: Pharmacological Assays written by Franz J. Hock and published by Springer. This book was released on 2015-11-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc.
