Gas Chromatographic Retention Indices Of Toxicologically Relevant Substances On Packed Or Capillary Columns With Dimethylsilicone Stationary Phases

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Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed or Capillary Columns with Dimethylsilicone Stationary Phases

Author : The International Association
Publisher : Wiley-VCH
ISBN 13 : 9783527273966
Total Pages : 406 pages
Book Rating : 4.2/5 (739 download)

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Book Synopsis Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed or Capillary Columns with Dimethylsilicone Stationary Phases by : The International Association

Download or read book Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed or Capillary Columns with Dimethylsilicone Stationary Phases written by The International Association and published by Wiley-VCH. This book was released on 1992-11-04 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: International experts have compiled data on some 5000 substances (an astounding expansion compared to the 600 and 1100 substances covered in the first and second editions respectively). The enlarged data base has been made possible by combining the extended DFG-TIAFT data base with the one developed by Pfleger, Maurer and Weber. The latter has been generated mainly on capillary columns and includes many toxicologically relevant metabolites seen in actual intoxications. The more polar substances, which are difficult to chromatograph, were derivatized before retention index measurement. In addition, data on a number of important substance classes such as pesticides, beta-blockers, benzodiazepines doping agents and non-steroidal antiinflammatory drugs were considerably extended. Moreover, this new edition also covers modern capillary gas chromatography.

Fundamentals of Analytical Toxicology

Author : Robert J. Flanagan
Publisher : John Wiley & Sons
ISBN 13 : 0470319348
Total Pages : 605 pages
Book Rating : 4.4/5 (73 download)

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Book Synopsis Fundamentals of Analytical Toxicology by : Robert J. Flanagan

Download or read book Fundamentals of Analytical Toxicology written by Robert J. Flanagan and published by John Wiley & Sons. This book was released on 2008-03-03 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electrophoresis, mass spectrometry, and immunoassay – are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: “This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.” Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists “Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background “Boxes”. The many and up to date literature references in each chapter demonstrate the authors’ thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.” GTFCh Bulletin “Toxichem + Krimtech”, May 2008 (translated, original review in German) “Many toxicologists will add this important reference to their libraries because it competently fills a need ...” International Journal of Toxicology “The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.” International Journal of Environmental Analytical Chemistry

Retention and Selectivity in Liquid Chromatography

Author : R.M. Smith
Publisher : Elsevier
ISBN 13 : 0080858651
Total Pages : 479 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Retention and Selectivity in Liquid Chromatography by : R.M. Smith

Download or read book Retention and Selectivity in Liquid Chromatography written by R.M. Smith and published by Elsevier. This book was released on 1995-01-13 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together a number of studies which examine the ways in which the retention and selectivity of separations in high-performance liquid chromatography are dependent on the chemical structure of the analytes and the properties of the stationary and mobile phases. Although previous authors have described the optimisation of separations by alteration of the mobile phase, little emphasis has previously been reported of the influence of the structure and properties of the analyte.The initial chapters describe methods based on retention index group increments and log P increments for the prediction of the retention of analytes and the ways in which these factors are influenced by mobile phases and intramolecular interactions. The values of a wide range of group increments in different eluents are tabulated.Different scales of retention indices in liquid chromatography are described for the comparison of separations, the identification of analytes and the comparison of stationary phases. Applications of these methods in the pharmaceutical, toxicology, forensic, metabolism, environmental, food and other fields are reviewed. The effects of different mobile phases on the selectivity of the retention indices are reported. A compilation of sources of reported retention index values are given.Methods for the comparison of stationary phases based on the interactions of different analytes are covered, including lipophilic and polar indices, shape selectivity comparisons, their application to novel stationary phases, and chemometric methods for column comparisons.

Proceedings of the International Symposium on Forensic Toxicology

Author :
Publisher :
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis Proceedings of the International Symposium on Forensic Toxicology by :

Download or read book Proceedings of the International Symposium on Forensic Toxicology written by and published by . This book was released on 1992 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists

Author : Hans Brandenberger
Publisher : Walter de Gruyter
ISBN 13 : 3110881616
Total Pages : 765 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists by : Hans Brandenberger

Download or read book Analytical Toxicology for Clinical, Forensic and Pharmaceutical Chemists written by Hans Brandenberger and published by Walter de Gruyter. This book was released on 2011-05-02 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at toxicologists and pharmacists involved in analytical work, this text provides critical evaluations of analytical possibilities to help with the choice of methods.

National Library of Medicine Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1328 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed Or Capillary Columns with Dimethylsilicone Stationary Phases

Author : Rokus A. De Zeeuw
Publisher : VCH Publishers
ISBN 13 : 9781560811824
Total Pages : 407 pages
Book Rating : 4.8/5 (118 download)

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Book Synopsis Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed Or Capillary Columns with Dimethylsilicone Stationary Phases by : Rokus A. De Zeeuw

Download or read book Gas Chromatographic Retention Indices of Toxicologically Relevant Substances on Packed Or Capillary Columns with Dimethylsilicone Stationary Phases written by Rokus A. De Zeeuw and published by VCH Publishers. This book was released on 1992-01-01 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advanced Chromatographic and Electromigration Methods in BioSciences

Author : I. Mikšík
Publisher : Elsevier
ISBN 13 : 0080858686
Total Pages : 1149 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Advanced Chromatographic and Electromigration Methods in BioSciences by : I. Mikšík

Download or read book Advanced Chromatographic and Electromigration Methods in BioSciences written by I. Mikšík and published by Elsevier. This book was released on 1998-09-28 with total page 1149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with chromatographic and electrophoretic methods applied for the separation (quantitation and identification) of biologically relevant compounds. It is assumed that the potential reader is familiar with the basics of chromatographic and electromigration methods. Individual separation modes are dealt with to an extent which follows their applicability for biomedical purposes: liquid chromatography and electromigration methods are therefore highlighted.Each chapter is completed with a list of recent literature covering the 1987-1997 period, which can be used for further guidance of the reader in his/her own field. The chapters have been written by specialists in a particular area and with an emphasis on applications to the biomedical field. This implies that theoretical and instrumental aspects are kept to a minimum which allows the reader to understand the text. Considerable attention is paid to method selection, detection and derivatization procedures and troubleshooting. The majority of examples given represent the analyses of typical naturally-occurring mixtures. Adequate attention is paid to the role of the biological matrix and sample pretreatment, and special attention is given to forensic, toxicological and clinical applications. The book is completed with an extensive Index of Compounds Separated.

Chemical Identification and its Quality Assurance

Author : Boris L. Milman
Publisher : Springer Science & Business Media
ISBN 13 : 3642153615
Total Pages : 295 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Chemical Identification and its Quality Assurance by : Boris L. Milman

Download or read book Chemical Identification and its Quality Assurance written by Boris L. Milman and published by Springer Science & Business Media. This book was released on 2013-06-17 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to show how to apply the principles of quality assurance to the identification of analytes (qualitative chemical analysis). After presenting the principles of identification and metrological basics, the author focuses on the reliability and the errors of chemical identification. This is then applied to practical examples such as EPA methods, EU, FDA, or WADA regulations. Two whole chapters are devoted to the analysis of unknowns and identification of samples such as foodstuffs or oil pollutions. Essential reading for researchers and professionals dealing with the identification of chemical compounds and the reliability of chemical analysis.

Thin-Layer Chromatographic Rf Values of Toxicologically Relevant Substances on Standardized Systems

Author : The International Association
Publisher : Wiley-VCH
ISBN 13 : 9783527273973
Total Pages : 318 pages
Book Rating : 4.2/5 (739 download)

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Book Synopsis Thin-Layer Chromatographic Rf Values of Toxicologically Relevant Substances on Standardized Systems by : The International Association

Download or read book Thin-Layer Chromatographic Rf Values of Toxicologically Relevant Substances on Standardized Systems written by The International Association and published by Wiley-VCH. This book was released on 1996-12-16 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides indispensable, reliable and comparable Rf values on toxicologically relevant substances. In comparison to the first edition, the number of substances covered has been increased from 1100 to some 1800 for the 10 systems that can be used for general screening purposes. These systems are known to work well for a large variety of drugs. However, additional, special TLC systems may be useful to provide adequate separations within specific chemical or pharmacological groups. Therefore, two special systems for pesticides and one special system to analyze benzodiazepine hydrolysis products (benzophenones) in urine have been added.

Chromatography

Author : E. Heftmann
Publisher : Elsevier
ISBN 13 : 0080472257
Total Pages : 706 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chromatography by : E. Heftmann

Download or read book Chromatography written by E. Heftmann and published by Elsevier. This book was released on 2004-04-16 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatography has emerged as the most important and versatile analytical method. The book is not only an updated version of Heftmann's classical text, but it covers areas of future importance, such as microfluidics and computer resources. Under his experienced guidance, authorities in each field have contributed their practical experience to an integrated treatment of modern micro analysis. Part B of this two volume set brings the traditional field of application up to date. These include amino acids and proteins, nucleic acids and their constituents, lipid, and carbohydrates. Special chapters are devoted to the most important areas of application: drug and environmental analysis. Forensic and phytochemical applications are covered for the first time. Together with an overview of computer resources, the subject index allows novices as well as experts to obtain rapid and authoritative guidance to analytical problems, such as choice of methods and optimization of techniques and instrumentation.1. Each chapter written by an authority 2. Thorough treatment of the theoretical basis of separation methods 3. Practical guide for performing analyses

Hair Testing for Drugs of Abuse

Author :
Publisher :
ISBN 13 :
Total Pages : 416 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hair Testing for Drugs of Abuse by :

Download or read book Hair Testing for Drugs of Abuse written by and published by . This book was released on 1995 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Catalog

Author : National Library of Medicine (U.S.)
Publisher :
ISBN 13 :
Total Pages : 824 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Reference Materials in Analytical Chemistry

Author : A. Zschunke
Publisher : Springer Science & Business Media
ISBN 13 : 3642569862
Total Pages : 248 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Reference Materials in Analytical Chemistry by : A. Zschunke

Download or read book Reference Materials in Analytical Chemistry written by A. Zschunke and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Under the guidance of the German Federal Institute for Materials Research (BAM), the standards for fabrication and application of reference materials are presented here in comprehensive form. The areas covered are analytical chemistry, materials science, environmental analysis, clinical and forensic toxicological analysis, and gas and food analysis. A standard reference for every analytical laboratory.

Profiles of Drug Substances, Excipients and Related Methodology

Author : Harry G. Brittain
Publisher : Academic Press
ISBN 13 : 0123876672
Total Pages : 400 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Profiles of Drug Substances, Excipients and Related Methodology by : Harry G. Brittain

Download or read book Profiles of Drug Substances, Excipients and Related Methodology written by Harry G. Brittain and published by Academic Press. This book was released on 2011-06-16 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. Presents comprehensive reviews covering all aspects of drug development and formulation of drugs Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others Meets the information needs of the drug development community

Forensic Science

Author :
Publisher : Elsevier
ISBN 13 : 0080554253
Total Pages : 1047 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Forensic Science by :

Download or read book Forensic Science written by and published by Elsevier. This book was released on 2011-09-22 with total page 1047 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic Science, Second Edition presents the applications of separation methods, manly chromatography, in forensic practice. The first part, devoted to forensic toxicology, contains reviews on forensic relevant groups of compounds, like: Opiate agonists, cocaine, amphetamines, hallucinogens, cannabinoids, sedatives and hypnotics, antidepressive and antipsychotic drugs, analgesics, antidiabetics, muscle relaxants, and mushroom toxins.In these parts, the preliminary immunochemical tests were also included, together with separation methods. Screening procedures used in forensic toxicology were presented in separate chapters on forensic screening with GC, GC-MS, HPLC, LC-MS, CE, and LC-ICP-MS. In the part on actual and emerging problems of forensic toxicology, following chapters were included: Analytical markers of alcohol abuse, toxicological aspects of herbal remedies, drugs and driving, analysis in alternative matrices, doping analysis, pharmacogenomics in forensic toxicology, and quality assurance. The second part presents application of separation methods in forensic chemistry, and comprises chapters on: Explosives, chemical warfare agents, arson analysis, and writing media. Third part on forensic identification contains chapter on forensic genetics.All chapters are written up-to-date and present specific information up to 2006. The authors of each chapter are known not only from their scientific activity, but are also reputed experts, proven in everyday forensic casework. - Wide spectrum of topics presented - Up-to-date presentation of topics - Data are presented in comparative mode - Special stress put on screening procedures

Human Toxicology

Author : J. Descotes
Publisher : Elsevier
ISBN 13 : 0080534228
Total Pages : 859 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Human Toxicology by : J. Descotes

Download or read book Human Toxicology written by J. Descotes and published by Elsevier. This book was released on 1996-09-02 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: This excellent volume was designed and edited with two major ideas in mind: firstly, the field of clinical toxicology is changing and an acknowledgement of these changes is warranted; secondly, no comprehensive compilation of recently published case reports of, and clinical studies on, human poisonings is available, which is in sharp contrast to the closely related field of drug-induced side-effects.The book focusses on issues of recent concern, or issues poorly documented in the past. It is important that clinical toxicologists gain a better knowledge of all the available techniques of toxicological analysis. A better understanding of the way a sound interpretation of results should be conducted for the benefit of the patient's management, and a comprehensive set of data on the kinetics of the most common pharmaceutical drugs and many chemicals is required.Human Toxicology is a timely reference work which will be welcomed by a broad audience of toxicology professionals.