Gangliosides

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GM3 Signaling

Author : Cheorl-Ho Kim
Publisher : Springer Nature
ISBN 13 : 9811556520
Total Pages : 135 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis GM3 Signaling by : Cheorl-Ho Kim

Download or read book GM3 Signaling written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2020-07-10 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field.

Structure and Function of Gangliosides

Author : Lars Svennerholm
Publisher : Springer Science & Business Media
ISBN 13 : 1468478443
Total Pages : 556 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Structure and Function of Gangliosides by : Lars Svennerholm

Download or read book Structure and Function of Gangliosides written by Lars Svennerholm and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume records the proceedings of an International Symposium on The Structure and Function of Gangliosides, held at Le Bischenberg, Alsace, France, in April 23-27, 1979. The meeting was convened to get a comprehensive view of the immense activity that had occurred in the field since the previous conference on gangliosides held at Mont Sainte-Odile, ~lsace, France, in April 1973. At a conference on Enzymes of Lipid Metabolism held at the same place in April, 1977, several of the participants from the first ganglioside conference in 1973 met again. All previous participants agreed that the first meeting with its many frank and stimulating lectures, round tables and informal discussions had been of tremendous importance for the activity in the field and led to many personal contacts and a warm friendship among the ganglioside researchers. The success of the first meeting must be ascribed largely to one single man, PAUL MANDEL. Therefore, we decided to dedicate the next ganglioside conference to hirn and I was given the privilege to arrange the meeting together with him and staff members at Centre de Neurochirnie, Strasbourg. The Symposium on The Structure and Function of Gangliosides was arranged to honour PAUL MANDEL for his unique and never failing efforts to promote and strengthen international col laboration in all fields of neurochemistry.

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Biological Function of Gangliosides

Author : L. Svennerholm
Publisher : Elsevier
ISBN 13 : 0444816585
Total Pages : 429 pages
Book Rating : 4.4/5 (448 download)

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Book Synopsis Biological Function of Gangliosides by : L. Svennerholm

Download or read book Biological Function of Gangliosides written by L. Svennerholm and published by Elsevier. This book was released on 1994-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral neuropathies, and the controversial role of gangliosides, also in therapeutic administration. There is a section on the role of gangliosides in neuronal differentiation and development and their receptor functions and cell surface activities. This excellent addition to the renowned Progress in Brain Research series also contains an invaluable plenary lecture on molecular basis of cell adhesion by Nobel prizewinner Gerald Edelman.

Medical Applications of Mass Spectrometry

Author : Karoly Vekey
Publisher : Elsevier
ISBN 13 : 0080554652
Total Pages : 607 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Medical Applications of Mass Spectrometry by : Karoly Vekey

Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.

Sialic Acids, Part II: Biological and Biomedical Aspects

Author : David C. Baker
Publisher : Academic Press
ISBN 13 : 0128171480
Total Pages : 196 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sialic Acids, Part II: Biological and Biomedical Aspects by : David C. Baker

Download or read book Sialic Acids, Part II: Biological and Biomedical Aspects written by David C. Baker and published by Academic Press. This book was released on 2019-03-07 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sialic Acids, Volume 76, the most recent release in the Advances in Carbohydrate Chemistry and Biochemistry series, is the second volume of a two-volume set devoted to the sialic acids. Vol. 76, devoted to the biological and biomedical aspects of sialic acids, includes chapters on "Sialic Acids in Neurology," "Sialic Acids in Nonenveloped Virus Infections," and "The Biology of Gangliosides," all written by leading experts in their fields. - Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research - Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates - Informs and updates on all the latest developments in the field

Ganglioside Structure, Function, and Biomedical Potential

Author : Robert W. Ledeen
Publisher : Springer Science & Business Media
ISBN 13 : 1468412000
Total Pages : 626 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Ganglioside Structure, Function, and Biomedical Potential by : Robert W. Ledeen

Download or read book Ganglioside Structure, Function, and Biomedical Potential written by Robert W. Ledeen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the symposium on "Ganglioside Structure, Function and Biomedical Potential" which was held at Parksville, Vancouver Island, B. C. , Canada on July 6-10, 1983. The symposium was organized ao a satellite to the ninth meeting of the International Society for Neurochemistry, held immediately afterward in Vancouver City, B. C. Close to 50 speakers from 9 countries presented papers on a wide range of topics on the ganglioside theme. These encompassed the many aspects of basic research that have evolved over the past half-century, as well as some newer topics relating to the biomedical potential of gangliosides as therapeutic agents. One of the purposes of the meeting was to encourage dialogue between investigators in these seemingly diverse areas in the hope that each would come away with fresh perspective toward his own work. Judging from the many spirited, informed discussions that took place throughout the four day meeting, this goal was achieved. The charm and beauty of Vancouver Island undoubtedly contributed to the congenial atmosphere which quickly developed among the 120 or so participants. Drawn from 13 countries of Europe (East and West), America (North and South), Asia and the Middle East, this gathering reflected the broad geographical scale on which ganglioside research is now conducted. That this field is still in its "logarithmic" stage of growth is indicated by the increasing number of citations appearing each year in the various abstracts (e. g. fig. next page).

Gangliosides

Author : Sandro Sonnino
Publisher : Humana Press
ISBN 13 : 9781493985517
Total Pages : 456 pages
Book Rating : 4.9/5 (855 download)

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Book Synopsis Gangliosides by : Sandro Sonnino

Download or read book Gangliosides written by Sandro Sonnino and published by Humana Press. This book was released on 2018-06-21 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores methods of examining gangliosides, membrane amphiphilic lipids that are deeply involved in the modulation of the overall properties of cellular membranes, as well as of the functions of membrane-associated proteins. The contents take into account the vital availability of new enzymatic approaches, the knowledge of an incredibly extensive number of glyco-enzymes, and the improvement of multi-genetic analyses. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Gangliosides: Methods and Protocols serves as a valuable guidebook for entering in the vast research world of gangliosides.

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neuroimmune Pharmacology

Author : Tsuneya Ikezu
Publisher : Springer Science & Business Media
ISBN 13 : 0387725733
Total Pages : 850 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Neuroimmune Pharmacology by : Tsuneya Ikezu

Download or read book Neuroimmune Pharmacology written by Tsuneya Ikezu and published by Springer Science & Business Media. This book was released on 2008-03-21 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer’s and Parkinson’s as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.

Ganglioside Function

Author : Giuseppe Porcellati
Publisher : Springer
ISBN 13 : 1461446147
Total Pages : 301 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Ganglioside Function by : Giuseppe Porcellati

Download or read book Ganglioside Function written by Giuseppe Porcellati and published by Springer. This book was released on 2013-11-21 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume which is here presented reports all the lectures given at the International Satellite Meeting on Biochemical and Pharmacological Implications of Ganglioside Function held at Cor tona, Tuscany, Italy from 28 to 31 August, 1975. The Meeting was run just before the 5th International Congress of the International Society for Neurochemistry (Barcelona, 2-7 september, 1975) and was in fact organized on its frame. The general subject matter of gangliosides structure, biosyn thesis and degradation, of their functional role in neurochemistry, their pharmacological action and future potentialities, was deeply and throughly taken into consideration during the three-day Sympo sium, which was brilliantly directed and guided by Dr. L. Svenner holm. The meeting gave certainly, in our opinion, a valuable stimu lus to research workers interested in the biophysics, chemistry, biochemistry, physiology and pharmacology of gangliosides. The e ditors wish to express their thanhd to the speakers, the discussants, the Meeting Chairman, the section chairmen and to all the attendants who have taken part at the Symposium and who actively and deeply discussed the delivered lectures. Our final thank is also for Dr. Francesco della Valle, official representative of FIDIA Research Laboratories, Abano Terme, Padua, Italy, to whom we are grateful for his continuous and efficient support. The contribution of the Secretarial Staffs of both the v PREFACE Department of Biochemistry of Perugia University and FIDIA Labora tories to the editorial work is also gratefully acknowledged.

Ganglioside Biochemistry

Author : Cheorl-Ho Kim
Publisher : Springer Nature
ISBN 13 : 9811558159
Total Pages : 223 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Ganglioside Biochemistry by : Cheorl-Ho Kim

Download or read book Ganglioside Biochemistry written by Cheorl-Ho Kim and published by Springer Nature. This book was released on 2020-07-03 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry. The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc), which cannot be synthesized by humans, and on general aspects of ganglioside research. Ganglioside adsorption, disorders of ganglioside degradation, and the regulation of gangliosides are thoroughly discussed. A major focus of the book is the role of gangliosides in cancer. Here, the discussion encompasses, for example, the biological importance, antigenicity, and immunological actions of tumor-associated gangliosides (TAGs), the significance of different glycolipids and gangliosides as TAGs, and emerging anti-cancer vaccine strategies. The ability of sialic acids and TAGs of tumor cells to escape immunosurveillance and immunoediting also receives detailed attention. The significance of sialic acids in regulation of the complement system is explained, and the closing chapter focuses especially on the role of sialyl T antigen in cancer. The book will be of value for all who are interested in functional glycobiology and glycomic studies.

Biology of the Sialic Acids

Author : A. Rosenberg
Publisher : Springer Science & Business Media
ISBN 13 : 9780306449741
Total Pages : 398 pages
Book Rating : 4.4/5 (497 download)

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Book Synopsis Biology of the Sialic Acids by : A. Rosenberg

Download or read book Biology of the Sialic Acids written by A. Rosenberg and published by Springer Science & Business Media. This book was released on 1995-07-31 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables.

Glycolipids

Author :
Publisher : Elsevier
ISBN 13 : 0080860680
Total Pages : 327 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Glycolipids by :

Download or read book Glycolipids written by and published by Elsevier. This book was released on 2011-09-22 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycolipids

Hemostasis and Thrombosis

Author : Robert W. Colman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781749964
Total Pages : 1903 pages
Book Rating : 4.7/5 (817 download)

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Book Synopsis Hemostasis and Thrombosis by : Robert W. Colman

Download or read book Hemostasis and Thrombosis written by Robert W. Colman and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 1903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pre-eminent reference on coagulation disorders is now in its thoroughly updated Fifth Edition. Written by more than 160 of the world's foremost authorities, this encyclopedic volume integrates basic science and clinical practice and details all that is currently known about blood clotting disorders and how to manage patients with these and related problems. This edition has been reorganized into smaller, more tightly focused chapters to help readers find information easily. A new co-editor, Samuel Z. Goldhaber, MD, has expanded the cardiology portion of the book. Other new features include a two-color page design and more than 100 full-color illustrations.

Lipids in Infant Nutrition

Author : Andrew J. Sinclair
Publisher : The American Oil Chemists Society
ISBN 13 : 9780935315929
Total Pages : 312 pages
Book Rating : 4.3/5 (159 download)

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Book Synopsis Lipids in Infant Nutrition by : Andrew J. Sinclair

Download or read book Lipids in Infant Nutrition written by Andrew J. Sinclair and published by The American Oil Chemists Society. This book was released on 1998-05-30 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eighteen articles present the latest research, covering topics connected with infant nutrition and antioxidants, cholesterol, triglycerides, and the effect of diet. A sampling of article topics: possible roles of maternal and perinatal long-chain fatty acids in preterm birth; enzymes in human milk; role of gangliosides in infant nutrition; and early diet influences on hepatic lipogenesis. Annotation copyrighted by Book News, Inc., Portland, OR

Synthesis and Characterization of Glycosides

Author : Marco Brito-Arias
Publisher : Springer Science & Business Media
ISBN 13 : 0387707921
Total Pages : 362 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Synthesis and Characterization of Glycosides by : Marco Brito-Arias

Download or read book Synthesis and Characterization of Glycosides written by Marco Brito-Arias and published by Springer Science & Business Media. This book was released on 2007-03-12 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.