Fundamentals Of Epigenetics

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Introduction to Epigenetics

Author : Renato Paro
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Introduction to Epigenetics by : Renato Paro

Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Fundamentals of Epigenetics

Author : Gurbachan S. Miglani
Publisher : I K International Pvt Ltd
ISBN 13 : 939062097X
Total Pages : 1048 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Fundamentals of Epigenetics by : Gurbachan S. Miglani

Download or read book Fundamentals of Epigenetics written by Gurbachan S. Miglani and published by I K International Pvt Ltd. This book was released on 2023-05-23 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Epigenetics provides concise yet complete information on the many aspects of the basic and most recent concepts in epigenetics, a branch of life science that deals with the mechanisms such as DNA modifications, histone modifications, RNA modifications, small and long non-coding RNAs, chromatin remodeling, which are involved in epigenetic control of gene expression without involving variations in DNA sequences. These regulatory mechanisms lead to phenotypic variations. These epigenetic mechanisms can be exploited for crop improvement and cure of human diseases. This book is primarily designed for undergraduate and graduate level students studying epigenetics in conventional, agricultural and medicinal universities. Teachers and researchers in any discipline of life sciences, agricultural sciences, medicine, and biotechnology, molecular epigenetics and biotechnology will also find it useful as a reference book.

Clinical Precision Medicine

Author : Judy S. Crabtree
Publisher : Academic Press
ISBN 13 : 0128204028
Total Pages : 114 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Clinical Precision Medicine by : Judy S. Crabtree

Download or read book Clinical Precision Medicine written by Judy S. Crabtree and published by Academic Press. This book was released on 2019-11-15 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics Features chapter contributions from leaders in the field Consolidates fundamental concepts and current practices of precision medicine in one convenient resource

Twin and Family Studies of Epigenetics

Author : Shuai Li
Publisher : Academic Press
ISBN 13 : 0128209526
Total Pages : 376 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Twin and Family Studies of Epigenetics by : Shuai Li

Download or read book Twin and Family Studies of Epigenetics written by Shuai Li and published by Academic Press. This book was released on 2021-08-19 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders Features chapter contributions from a wide range of international researchers in the field

Nutrition in Epigenetics

Author : Mihai D. Niculescu
Publisher : John Wiley & Sons
ISBN 13 : 081381605X
Total Pages : 382 pages
Book Rating : 4.8/5 (138 download)

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Book Synopsis Nutrition in Epigenetics by : Mihai D. Niculescu

Download or read book Nutrition in Epigenetics written by Mihai D. Niculescu and published by John Wiley & Sons. This book was released on 2011-06-28 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of epigenetics, or how heritable changes in gene expression are regulated without modifying the coding DNA sequence, has become an increasingly important field of study in recent years. Rapid developments in our understanding of the way in which gene function is modulated by the environment has revolutionized the way we think about human development and health. Nutrition in Epigenetics reviews the latest research looking at the interaction between genes and nutrients and the role they play together in maintaining human health. Nutrition in Epigenetics is divided into two primary parts. The first part provides key principles such as epigenetic mechanisms, developmental epigenetics, and the role of epigenetics in disease. The second part looks specifically at the application of epigenetics to the field of human nutrition. Chapters review the role of specific nutrients in modulating epigenetic status and the effect on health and disease. Nutrition in Epigenetics is an indispensable resource for researchers, professionals and advanced students with an interest in human nutrition, epigenetics, and biomedical research.

Toxicoepigenetics

Author : Shaun D. McCullough
Publisher : Academic Press
ISBN 13 : 0128124342
Total Pages : 430 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Toxicoepigenetics by : Shaun D. McCullough

Download or read book Toxicoepigenetics written by Shaun D. McCullough and published by Academic Press. This book was released on 2018-11-02 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects of toxicology such as the role of the environment and lifestyle influencing the individual susceptibility to these effects and the trans-generational transmission of these health effects and susceptibilities. Methods chapters are included to help improve efficacy and efficiency of protocols in both the laboratory and the classroom. Toxicoepigenetics: Core Principles and Applications is an essential book for researchers and academics using epigenetics in toxicology research and study. Introduces the fundamental principles and practices for understanding the role of the epigenome in toxicology Presents the foundation of epigenetics for toxicologists with a broad range of backgrounds Discusses the incorporation of epigenetics and epigenomics into current toxicological studies and interpretation of epigenetic data in toxicological applications

The Developing Genome

Author : David Scott Moore
Publisher : Oxford University Press, USA
ISBN 13 : 0199922349
Total Pages : 321 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Developing Genome by : David Scott Moore

Download or read book The Developing Genome written by David Scott Moore and published by Oxford University Press, USA. This book was released on 2015 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: An accessible introduction to behavioral epigenetics, The Developing Genome explores how experiences influence genetic activity. We develop as we do not because of the genes we have, but because of what our genes do. The Developing Genome explains this new discipline and its revolutionary implications, changing how we understand development and evolution.

Fundamentals of Chromatin

Author : Jerry L. Workman
Publisher : Springer Science & Business Media
ISBN 13 : 1461486246
Total Pages : 594 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Fundamentals of Chromatin by : Jerry L. Workman

Download or read book Fundamentals of Chromatin written by Jerry L. Workman and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.

Epigenetics for Beginners

Author : June Corder
Publisher :
ISBN 13 :
Total Pages : 51 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Epigenetics for Beginners by : June Corder

Download or read book Epigenetics for Beginners written by June Corder and published by . This book was released on 2021-08-21 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your genes play an important role in your health, but so do your behaviors and environment, such as what you eat and how physically active you are. Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work. Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but they can change how your body reads a DNA sequence. Gene expression refers to how often or when proteins are created from the instructions within your genes. While genetic changes can alter which protein is made, epigenetic changes affect gene expression to turn genes "on" and "off." Since your environment and behaviors, such as diet and exercise, can result in epigenetic changes, it is easy to see the connection between your genes and your behaviors and environment. Researchers studying the microscopic roundworm Caenorhabditis elegans recently discovered a set of mutations that extended the worms' normal 2-3 week lifespan by up to 30%. This was exciting, not least because discoveries in animals such as roundworms can sometimes help us understand processes like ageing in humans. This was not the end of the story though, as the researchers found that the descendants of the long-lived roundworms could also live longer than normal, even if they only inherited the non-mutated version of the genes from their parents. This doesn't seem to make sense at first; surely characteristics such as hair colour, height and even how long we or a microscopic worm could potentially live are carried in the DNA sequence of the genes that we inherit from our parents. So how can we solve the conundrum of how the roundworms inherited the long lived characteristic, without inheriting the DNA sequence that initially caused it? The answer is epigenetics. GET YOUR COPY TODAY BY SCROLLING UP AND CLICKING BUY NOW TO GET YOUR COPY TODAY

Chromatin And Epigenetics: An Introduction To Epigenetic Mechanisms

Author : Vincenzo Pirrotta
Publisher : World Scientific
ISBN 13 : 9811257647
Total Pages : 525 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Chromatin And Epigenetics: An Introduction To Epigenetic Mechanisms by : Vincenzo Pirrotta

Download or read book Chromatin And Epigenetics: An Introduction To Epigenetic Mechanisms written by Vincenzo Pirrotta and published by World Scientific. This book was released on 2023-07-05 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to epigenetics, a controversial term that denotes the mechanisms that instruct the genome on how to express the purely genetic information that encodes proteins. Starting with the discovery of repressor proteins in the 1960s, epigenetics evolved into a kind of user manual for the genetic information, telling the genome if, when, how much and in what cells to read genes. Advances in epigenetics in the past 15 years have revealed how it lies at the heart of virtually every branch of biological and medical sciences and an understanding of its basic principles is therefore essential for every student in this field.The field of chromatin and epigenetics has developed very rapidly in the past 15-20 years. The pace in the field of epigenetics has now slowed down, the basic outlines of the mechanisms and implications have solidified and a consensus has been achieved among the researchers in the field. At the same time, these mechanisms and implications are now an integral part of how we think about the genome. Genes are more than just DNA and more than just protein-coding sequences and this realization has revolutionized our understanding of the genome, gene expression and its regulation in development, health and disease. It is time, therefore, for a textbook to help train a new generation of biologists and health scientists as well as providing a basic competence among practitioners in allied fields. The present book has grown out of a course given for the past 13 years to advanced undergraduates at Rutgers University. In keeping with the experience in that course, the book is abundantly illustrated, presents a wealth of specific examples, and includes a chapter describing a number of methods and techniques that have driven the advances in the field.

Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications

Author : Raúl Alvarez-Venegas
Publisher : Springer
ISBN 13 : 3319079719
Total Pages : 158 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications by : Raúl Alvarez-Venegas

Download or read book Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications written by Raúl Alvarez-Venegas and published by Springer. This book was released on 2014-07-22 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decades, chromatin remodelling has emerged as an important regulator of gene expression and plant defense. This book provides a detailed understanding of the epigenetic mechanisms involved in plants of agronomic importance. The information presented here is significant because it is expected to provide the knowledge needed to develop in the future treatments to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases and to increase crop productivity. New approaches of this kind and the development of new technologies will certainly increase our knowledge of currently known post-translational modifications and facilitate the understanding of their roles in, for example, host-pathogen interactions and crop productivity. Furthermore, we provide important insight on how the plant epigenome changes in response to developmental or environmental stimuli, how chromatin modifications are established and maintained, to which degree they are used throughout the genome, and how chromatin modifications influence each another.

Epigenetic Mechanisms of Gene Regulation

Author : Vincenzo E. A. Russo
Publisher :
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epigenetic Mechanisms of Gene Regulation by : Vincenzo E. A. Russo

Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

Epigenetics in Human Disease

Author : Trygve Tollefsbol
Publisher : Academic Press
ISBN 13 : 0123884160
Total Pages : 617 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Epigenetics in Human Disease by : Trygve Tollefsbol

Download or read book Epigenetics in Human Disease written by Trygve Tollefsbol and published by Academic Press. This book was released on 2012-07-26 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications

Author : Raúl Alvarez-Venegas
Publisher : Springer
ISBN 13 : 3030147606
Total Pages : 415 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications by : Raúl Alvarez-Venegas

Download or read book Epigenetics in Plants of Agronomic Importance: Fundamentals and Applications written by Raúl Alvarez-Venegas and published by Springer. This book was released on 2019-04-26 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, chromatin modulation has emerged as an important regulator of gene expression. This second edition provides detailed information on the epigenetic mechanisms in plants, illustrating the value of this research in plants of agronomic importance. It examines recent advances regarding plants’ epigenetic regulation in response to abiotic and biotic types of stress; the epigenetic basis of plant immunity; evolution and functions of plant histones; epigenetic variation and plant breeding; and epigenome editing and crop improvement. The content is intended to promote the development of future biotechnologies to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases, and to increase crop productivity. The development of new fields, like epigenome editing and RNA epigenetics, will certainly improve our understanding of currently known epigenetic modifications and their roles in e.g. host-pathogen interactions, crop productivity, and in response to environmental stimuli. This volume contains twelve new/revised chapters, written by an international team of experts on plant epigenetics, and addresses the needs of researchers and professionals in the fields of agronomics, crop breeding, epigenetics, plant biochemistry, plant developmental biology, and related disciplines.

Introducing Epigenetics

Author : Cath Ennis
Publisher : Icon Books Ltd
ISBN 13 : 1848319037
Total Pages : 285 pages
Book Rating : 4.8/5 (483 download)

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Book Synopsis Introducing Epigenetics by : Cath Ennis

Download or read book Introducing Epigenetics written by Cath Ennis and published by Icon Books Ltd. This book was released on 2017-02-02 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species. This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine. We'll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

Examining a Developmental Approach to Childhood Obesity

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030937698X
Total Pages : 256 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Examining a Developmental Approach to Childhood Obesity by : Institute of Medicine

Download or read book Examining a Developmental Approach to Childhood Obesity written by Institute of Medicine and published by National Academies Press. This book was released on 2015-09-08 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific evidence points to the origins of childhood obesity as an outcome of the dynamic interplay of genetic, behavioral, and environmental factors throughout early development, with a compelling body of evidence suggesting that both maternal and paternal nutritional and other exposures affect a child's risk of later obesity. The burgeoning field of epigenetics has led researchers to speculate that many of the observed associations between early developmental exposures and later risk of childhood obesity are mediated, at least in part, through epigenetic mechanisms. To explore the body of evolving science that examines the nexus of biology, environment, and developmental stage on risk of childhood obesity, the Institute of Medicine and the National Research Council convened a workshop in February 2015. The workshop focused on the prenatal period, infancy, and early childhood and addressed evidence from both animal and human studies. Workshop objectives were to (1) identify epigenetic-mediated relationships between exposure to risk factors during sensitive periods of development (gestation through age 3) and subsequent obesity-related outcomes; (2) explore the science around periods of plasticity and potential reversibility of obesity risk in the context of early childhood development; and (3) examine the translation of epigenetic science to guide early childhood obesity prevention and intervention to reduce obesity risk. This report summarizes the information presented and discussed at the workshop.

Essentials of Epigenetics

Author : Augustus Drew
Publisher : Foster Academics
ISBN 13 : 9781646466085
Total Pages : 0 pages
Book Rating : 4.4/5 (66 download)

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Book Synopsis Essentials of Epigenetics by : Augustus Drew

Download or read book Essentials of Epigenetics written by Augustus Drew and published by Foster Academics. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics refers to a field of study concerned with the changes in DNA that do not involve modifications to the underlying sequence. It entails genetic control by factors other than a person's DNA sequence. Epigenetic modifications can activate or deactivate genes and determine which proteins are transcribed. The modifications have various effects on gene expression. The types of epigenetic changes include non-coding RNA, DNA methylation and histone modification. Epigenetic patterns may be affected by a number of lifestyle factors including tobacco smoking, food, exposure to environmental toxins, working on night shifts, obesity, alcohol consumption, psychological stress and physical activity. Epigenetics is a developing area of scientific study that demonstrates how environmental influences such as children's experiences affect the expression of their genes. This book unravels the recent studies in the field of epigenetics. It presents researches and studies performed by experts across the globe. The readers would gain knowledge that would broaden their perspective in this area of study.