Functional Coherence Of Molecular Networks In Bioinformatics

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Functional Coherence of Molecular Networks in Bioinformatics

Author : Mehmet Koyutürk
Publisher : Springer Science & Business Media
ISBN 13 : 9781461403203
Total Pages : 228 pages
Book Rating : 4.4/5 (32 download)

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Book Synopsis Functional Coherence of Molecular Networks in Bioinformatics by : Mehmet Koyutürk

Download or read book Functional Coherence of Molecular Networks in Bioinformatics written by Mehmet Koyutürk and published by Springer Science & Business Media. This book was released on 2011-09-22 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective.

Functional Coherence of Molecular Networks in Bioinformatics

Author : Mehmet Koyutürk
Publisher :
ISBN 13 : 9781283355933
Total Pages : pages
Book Rating : 4.3/5 (559 download)

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Book Synopsis Functional Coherence of Molecular Networks in Bioinformatics by : Mehmet Koyutürk

Download or read book Functional Coherence of Molecular Networks in Bioinformatics written by Mehmet Koyutürk and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular networks provide descriptions of the organization of various biological processes, including cellular signaling, metabolism, and genetic regulation. Knowledge on molecular networks is commonly used for systems level analysis of biological function; research and method development in this area has grown tremendously in the past few years. This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize

Summarizing Biological Networks

Author : Sourav S. Bhowmick
Publisher : Springer
ISBN 13 : 331954621X
Total Pages : 146 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Summarizing Biological Networks by : Sourav S. Bhowmick

Download or read book Summarizing Biological Networks written by Sourav S. Bhowmick and published by Springer. This book was released on 2017-04-17 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the data mining, systems biology, and bioinformatics computational methods that can be used to summarize biological networks. Specifically, it discusses an array of techniques related to biological network clustering, network summarization, and differential network analysis which enable readers to uncover the functional and topological organization hidden in a large biological network. The authors also examine crucial open research problems in this arena. Academics, researchers, and advanced-level students will find this book to be a comprehensive and exceptional resource for understanding computational techniques and their applications for a summary of biological networks.

Biomolecular Networks

Author : Luonan Chen
Publisher : John Wiley & Sons
ISBN 13 : 9780470488058
Total Pages : 416 pages
Book Rating : 4.4/5 (88 download)

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Book Synopsis Biomolecular Networks by : Luonan Chen

Download or read book Biomolecular Networks written by Luonan Chen and published by John Wiley & Sons. This book was released on 2009-06-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.

Recent Advances in Biological Network Analysis

Author : Byung-Jun Yoon
Publisher : Springer Nature
ISBN 13 : 3030571734
Total Pages : 220 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Recent Advances in Biological Network Analysis by : Byung-Jun Yoon

Download or read book Recent Advances in Biological Network Analysis written by Byung-Jun Yoon and published by Springer Nature. This book was released on 2021-01-13 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights.

Computational Network Analysis with R

Author : Matthias Dehmer
Publisher : John Wiley & Sons
ISBN 13 : 3527694404
Total Pages : 368 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Computational Network Analysis with R by : Matthias Dehmer

Download or read book Computational Network Analysis with R written by Matthias Dehmer and published by John Wiley & Sons. This book was released on 2016-07-22 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new title in the well-established "Quantitative Network Biology" series includes innovative and existing methods for analyzing network data in such areas as network biology and chemoinformatics. With its easy-to-follow introduction to the theoretical background and application-oriented chapters, the book demonstrates that R is a powerful language for statistically analyzing networks and for solving such large-scale phenomena as network sampling and bootstrapping. Written by editors and authors with an excellent track record in the field, this is the ultimate reference for R in Network Analysis.

Computational Intelligence for Network Structure Analytics

Author : Maoguo Gong
Publisher : Springer
ISBN 13 : 9811045585
Total Pages : 283 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Computational Intelligence for Network Structure Analytics by : Maoguo Gong

Download or read book Computational Intelligence for Network Structure Analytics written by Maoguo Gong and published by Springer. This book was released on 2017-09-19 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest research advances in complex network structure analytics based on computational intelligence (CI) approaches, particularly evolutionary optimization. Most if not all network issues are actually optimization problems, which are mostly NP-hard and challenge conventional optimization techniques. To effectively and efficiently solve these hard optimization problems, CI based network structure analytics offer significant advantages over conventional network analytics techniques. Meanwhile, using CI techniques may facilitate smart decision making by providing multiple options to choose from, while conventional methods can only offer a decision maker a single suggestion. In addition, CI based network structure analytics can greatly facilitate network modeling and analysis. And employing CI techniques to resolve network issues is likely to inspire other fields of study such as recommender systems, system biology, etc., which will in turn expand CI’s scope and applications. As a comprehensive text, the book covers a range of key topics, including network community discovery, evolutionary optimization, network structure balance analytics, network robustness analytics, community-based personalized recommendation, influence maximization, and biological network alignment. Offering a rich blend of theory and practice, the book is suitable for students, researchers and practitioners interested in network analytics and computational intelligence, both as a textbook and as a reference work.

Modeling and Analysis of Bio-molecular Networks

Author : Jinhu Lü
Publisher : Springer Nature
ISBN 13 : 981159144X
Total Pages : 464 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Modeling and Analysis of Bio-molecular Networks by : Jinhu Lü

Download or read book Modeling and Analysis of Bio-molecular Networks written by Jinhu Lü and published by Springer Nature. This book was released on 2020-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a number of questions from the perspective of complex systems: How can we quantitatively understand the life phenomena? How can we model life systems as complex bio-molecular networks? Are there any methods to clarify the relationships among the structures, dynamics and functions of bio-molecular networks? How can we statistically analyse large-scale bio-molecular networks? Focusing on the modeling and analysis of bio-molecular networks, the book presents various sophisticated mathematical and statistical approaches. The life system can be described using various levels of bio-molecular networks, including gene regulatory networks, and protein-protein interaction networks. It first provides an overview of approaches to reconstruct various bio-molecular networks, and then discusses the modeling and dynamical analysis of simple genetic circuits, coupled genetic circuits, middle-sized and large-scale biological networks, clarifying the relationships between the structures, dynamics and functions of the networks covered. In the context of large-scale bio-molecular networks, it introduces a number of statistical methods for exploring important bioinformatics applications, including the identification of significant bio-molecules for network medicine and genetic engineering. Lastly, the book describes various state-of-art statistical methods for analysing omics data generated by high-throughput sequencing. This book is a valuable resource for readers interested in applying systems biology, dynamical systems or complex networks to explore the truth of nature.

Issues in Bioengineering and Bioinformatics: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464964173
Total Pages : 1824 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Issues in Bioengineering and Bioinformatics: 2011 Edition by :

Download or read book Issues in Bioengineering and Bioinformatics: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 1824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Bioengineering and Bioinformatics: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioengineering and Bioinformatics. The editors have built Issues in Bioengineering and Bioinformatics: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioengineering and Bioinformatics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Bioengineering and Bioinformatics: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Bioinformatics and Biomedical Engineering

Author : Ignacio Rojas
Publisher : Springer
ISBN 13 : 3319561545
Total Pages : 762 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Bioinformatics and Biomedical Engineering by : Ignacio Rojas

Download or read book Bioinformatics and Biomedical Engineering written by Ignacio Rojas and published by Springer. This book was released on 2017-03-30 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two volume set LNBI 10208 and LNBI 10209 constitutes the proceedings of the 5th International Work-Conference on Bioinformatics and Biomedical Engineering, IWBBIO 2017, held in Granada, Spain, in April 2017. The 122 papers presented were carefully reviewed and selected from 309 submissions. The scope of the conference spans the following areas: advances in computational intelligence for critical care; bioinformatics for healthcare and diseases; biomedical engineering; biomedical image analysis; biomedical signal analysis; biomedicine; challenges representing large-scale biological data; computational genomics; computational proteomics; computational systems for modeling biological processes; data driven biology - new tools, techniques and resources; eHealth; high-throughput bioinformatic tools for genomics; oncological big data and new mathematical tools; smart sensor and sensor-network architectures; time lapse experiments and multivariate biostatistics.

Handbook on Biological Networks

Author :
Publisher :
ISBN 13 : 9814468681
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Handbook on Biological Networks by :

Download or read book Handbook on Biological Networks written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Biological Networks

Author : Alpan Raval
Publisher : CRC Press
ISBN 13 : 1420010360
Total Pages : 329 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Introduction to Biological Networks by : Alpan Raval

Download or read book Introduction to Biological Networks written by Alpan Raval and published by CRC Press. This book was released on 2016-04-19 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap, Introduction to Biological Networks provides a thorough introduction to genomics-inspired network bi

Selected Works in Bioinformatics

Author : Xuhua Xia
Publisher : BoD – Books on Demand
ISBN 13 : 9533072814
Total Pages : 193 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Selected Works in Bioinformatics by : Xuhua Xia

Download or read book Selected Works in Bioinformatics written by Xuhua Xia and published by BoD – Books on Demand. This book was released on 2011-10-21 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of nine chapters covering a variety of bioinformatics subjects, ranging from database resources for protein allergens, unravelling genetic determinants of complex disorders, characterization and prediction of regulatory motifs, computational methods for identifying the best classifiers and key disease genes in large-scale transcriptomic and proteomic experiments, functional characterization of inherently unfolded proteins/regions, protein interaction networks and flexible protein-protein docking. The computational algorithms are in general presented in a way that is accessible to advanced undergraduate students, graduate students and researchers in molecular biology and genetics. The book should also serve as stepping stones for mathematicians, biostatisticians, and computational scientists to cross their academic boundaries into the dynamic and ever-expanding field of bioinformatics.

Protein Function Prediction for Omics Era

Author : Daisuke Kihara
Publisher : Springer Science & Business Media
ISBN 13 : 9400708815
Total Pages : 316 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Protein Function Prediction for Omics Era by : Daisuke Kihara

Download or read book Protein Function Prediction for Omics Era written by Daisuke Kihara and published by Springer Science & Business Media. This book was released on 2011-04-19 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene function annotation has been a central question in molecular biology. The importance of computational function prediction is increasing because more and more large scale biological data, including genome sequences, protein structures, protein-protein interaction data, microarray expression data, and mass spectrometry data, are awaiting biological interpretation. Traditionally when a genome is sequenced, function annotation of genes is done by homology search methods, such as BLAST or FASTA. However, since these methods are developed before the genomics era, conventional use of them is not necessarily most suitable for analyzing a large scale data. Therefore we observe emerging development of computational gene function prediction methods, which are targeted to analyze large scale data, and also those which use such omics data as additional source of function prediction. In this book, we overview this emerging exciting field. The authors have been selected from 1) those who develop novel purely computational methods 2) those who develop function prediction methods which use omics data 3) those who maintain and update data base of function annotation of particular model organisms (E. coli), which are frequently referred

Research in Computational Molecular Biology

Author : Martin Vingron
Publisher : Springer
ISBN 13 : 3540788395
Total Pages : 480 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Research in Computational Molecular Biology by : Martin Vingron

Download or read book Research in Computational Molecular Biology written by Martin Vingron and published by Springer. This book was released on 2008-04-03 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 12th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2008. It presents current issues in algorithmic, theoretical, and experimental bioinformatics.

The Practical Bioinformatician

Author : Limsoon Wong
Publisher : World Scientific
ISBN 13 : 9814482625
Total Pages : 540 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis The Practical Bioinformatician by : Limsoon Wong

Download or read book The Practical Bioinformatician written by Limsoon Wong and published by World Scientific. This book was released on 2004-05-24 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computer scientists have increasingly been enlisted as “bioinformaticians” to assist molecular biologists in their research. This book is a practical introduction to bioinformatics for these computer scientists. The chapters are in-depth discussions by expert bioinformaticians on both general techniques and specific approaches to a range of selected bioinformatics problems. The book is organized into clusters of chapters on the following topics: • Overview of modern molecular biology and a broad spectrum of techniques from computer science — data mining, machine learning, mathematical modeling, sequence alignment, data integration, workflow development, etc. • In-depth discussion of computational recognition of functional and regulatory sites in DNA sequences. • Incisive discussion of computational prediction of secondary structure of RNA sequences. • Overview of computational prediction of protein cellular localization, and selected discussions of inference of protein function. • Overview of methods for discovering protein–protein interactions. • Detailed discussion of approaches to gene expression analysis for the diagnosis of diseases, the treatment of diseases, and the understanding of gene functions. • Case studies on analysis of phylogenies, functional annotation of proteins, construction of purpose-built integrated biological databases, and development of workflows underlying the large-scale-effort gene discovery. Contents:Molecular Biology for the Practical BioinformaticianStrategy and Planning of Bioinformatics ExperimentsData Mining Techniques for the Practical BioinformaticianTechniques for Recognition of Translation Initiation SitesHow Neural Networks Find Promoters Using Recognition of Micro-Structural Promoter ComponentsNeural-Statistical Model of TATA-Box Motifs in EukaryotesTuning the Dragon Promoter Finder System for Human Promoter RecognitionRNA Secondary Structure PredictionProtein Localization PredictionHomology Search MethodsAnalysis of Phylogeny: A Case Study on SaururaceaeFunctional Annotation and Protein Families: From Theory to PracticeDiscovering Protein–Protein InteractionsTechniques for Analysis of Gene ExpressionGenome-Wide cDNA Oligo Probe Design and Its Applications in i>Schizosaccharomyces PombeMining New Motifs from cDNA Sequence DataTechnologies for Biological Data IntegrationConstruction of Biological Databases: A Case Study on the Protein Phosphatase DataBase (PPDB)A Family Classification Approach to Functional Annotation of ProteinsInformatics for Efficient EST-Based Gene Discovery in Normalized and Subtracted cDNA Libraries Readership: Computer scientists planning to be a bioinformatician; computer science undergraduates in their sophomore and/or senior years. Keywords:Regularotory Site Recognition;Sequence Homology Search;Gene Expression Analysis;Protein Functional Annotation;RNA Secondary Structure Prediction;Computational Gene Discovery;Bioinformatics;Data MiningKey Features:Written in a practical, in-depth tutorial styleCovers a broad range of bioinformatics topics and of techniques used in bioinformaticsComprehensive overviews of the development of various approaches in a number of selected topicsIn-depth exposition of a number of important topicsContributions by prominent researchers: Vladimir Bajic, Ming Li, Kenta Nakai, Limsoon Wong, Cathy Wu, etc.Extensive, integrated references to background literature