Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

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Publisher : Bentham Science Publishers
ISBN 13 : 9811447500
Total Pages : 166 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7 by : Zareen Amtul

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7 written by Zareen Amtul and published by Bentham Science Publishers. This book was released on 2020-08-07 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The seventh volume of this series features reviews that cover the following topics related to the treatment of neurodegenerative diseases, epilepsy and stroke: -Fatty Acid Amides as a New Potential Therapeutic Agent in Multiple Sclerosis -Epileptic Seizures Detection Based on Non-Linear Characteristics Coupled with Machine Learning Techniques -Hampering Essential Tremor Neurodegeneration in Essential Tremor: Present and Future Directions -The Potential Therapeutic Role of the Melatoninergic System in Treatment of Epilepsy and Comorbid Depression -Modeling Neurodegenerative Diseases Using Transgenic Model of Drosophila -Genetic Basis in Stroke Treatment: Targets of Potent Inhibitors

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 10

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Publisher : Bentham Science Publishers
ISBN 13 : 9815040685
Total Pages : 362 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 10 by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 10 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2022-04-07 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. Volume 10 of the series continues to present novel information about new and interesting approaches to treat common neurological disorders, with a focus on neurodegeneration and pain medicine. The volume presents 7 detailed reviews in total. - Neurodegenerative disease: prevention and treatment through plant extracts therapy - Emerging novel approaches and recent advances in Parkinson’s disease treatment and diagnosis - Neurotrophic factors to combat neurodegeneration - Neural bases of executive function in ADHD children as assessed using FNIRS - Modulation of mesenchymal stem cells, glial cells and the immune system by oligodeoxynucleotides as a novel multi-target therapeutic approach against chronic pain - Chronic pain: focus on anticonvulsants - A review of the impact of testosterone on brain and aging-related decline in brain behavioural function

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

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Publisher :
ISBN 13 : 9781608059270
Total Pages : pages
Book Rating : 4.0/5 (592 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders written by Atta-ur-Rahman and published by . This book was released on 2015-07-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an ebook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the ebook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.

Frontiers in Clinical Drug Research- Central Nervous System

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Publisher : Bentham Science Publishers
ISBN 13 : 168108189X
Total Pages : 247 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Frontiers in Clinical Drug Research- Central Nervous System by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research- Central Nervous System written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-12-16 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Central Nervous System presents the latest researches and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals. The second volume of the series features chapters on the following topics: - Nucleic acids as drugs for neurodegenerative diseases - Cellular Cysteine Network (CYSTEINET): - Non-motor Symptoms in Parkinson’s Disease and drug therapies - Multi-modal pharmacological treatments for major depressive disorder

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

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Publisher : Frontiers in Clinical Drug Res
ISBN 13 : 9781681085869
Total Pages : 288 pages
Book Rating : 4.0/5 (858 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders by : Atta Ur Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders written by Atta Ur Rahman and published by Frontiers in Clinical Drug Res. This book was released on 2018-01-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The fifth volume of this series features reviews that cover the following topics: -drug treatment for spinal cord injury -action tremors -natural products for Alzheimer's disease treatment -non pharmacological approaches towards pain management -biosensors for detecting neurodegenerative diseases -NMDA receptor targeting -alkaloid antidepressants

Frontiers in Clinical Drug Research- Central Nervous System

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Publisher : Bentham Science Publishers
ISBN 13 : 1608057798
Total Pages : 252 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Frontiers in Clinical Drug Research- Central Nervous System by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research- Central Nervous System written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2013-10-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Central Nervous System presents the latest research and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals. The first volume of the series features chapters on the following topics: -Nerve targets in pain medicine -Spinal cord injury -Research on neurotoxins targeting voltage gated ion channels -G protein coupled receptor agonists and modulators -Drug research on mediating hypoxia in developing white matter

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 12

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Publisher : Bentham Science Publishers
ISBN 13 : 9815179853
Total Pages : 275 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 12 by : Zareen Amtul

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 12 written by Zareen Amtul and published by Bentham Science Publishers. This book was released on 2024-03-11 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in neurology and allied disciplines. The twelfth volume of this series features these reviews: Chapter 1: Recent Drugs Tested in Clinical Trials for Alzheimer's and Parkinson's Diseases Treatment: Current Approaches in Tracking New Drugs Chapter 2: Neurobiology of Placebo: Interpreting Its Evolutionary Origin, Meaning, Mechanisms, Monitoring, and Implications in Therapeutics Chapter 3: Role of Gut Microbiota in Neuroinflammation and Neurological Disorders Chapter 4: The Role of Age in Pediatric Tumors of the Central Nervous System Chapter 5: Drug Repurposing in CNS and Clinical Trials: Recent Achievements and Perspectives Focusing on Epilepsy and Related Comorbidities Chapter 6: Progress on the Development of Oxime Derivatives as a Potential Antidote for Organophosphorus Poisoning Readership Pharmaceutical scientists, clinical researchers, medical consultants and allied healthcare professionals interested in neuropharmacology and neurology

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9

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Publisher : Bentham Science Publishers
ISBN 13 : 168108905X
Total Pages : 279 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9 by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2021-10-15 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The ninth volume of this series features reviews that cover the following topics related to the treatment of a different CNS disorders, related diseases and basic neuropharmacology research: - Integrating imaging and microdialysis into systems neuropharmacology - Depression heterogeneity and the potential of a transdiagnostic and dimensional approach to identify biologically relevant phenotypes - CAR-T cells in brain tumors and autoimmune diseases – from basics to the clinic - Revaluation of thyrotropin-releasing hormone and its mimetics as candidates for treating a wide range of neurological and psychiatric disorders - Natural BACE1 inhibitors: promising drugs for the management of Alzheimer’s disease - The possibilities of safe lithium therapy in the treatment of neurological and psychoemotional disorders - Pharmacotherapy of multiple sclerosis and treatment strategies

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 11

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Publisher : Bentham Science Publishers
ISBN 13 : 9815123327
Total Pages : 339 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 11 by : Zareen Amtul

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 11 written by Zareen Amtul and published by Bentham Science Publishers. This book was released on 2023-05-02 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The eleventh volume of this series features reviews that cover the following topics related to the treatment of a variety of CNS disorders, related diseases, and basic research: - The Multi-target Directed Ligands candidate (MTDLs) prototypes for neurodegenerative diseases - Drugs for relapse prevention in addiction - Neuroprotective activities of cinnamic acids and their derivatives in neurodegenerative disorders - Phytosome for targeted delivery of natural compounds in treating alzheimer's disease - Physical activity as a non-pharmacologic method for treatment of alzheimer’s disease

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 8

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Publisher : Bentham Science Publishers
ISBN 13 : 9811470065
Total Pages : 174 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 8 by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 8 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-11-03 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The eighth volume of this series features reviews that cover the following topics related to the treatment of a variety of CNS disorders, related diseases and basic research: - Emerging Innovative Therapies of Spinal Muscular Atrophy: Current Knowledge and Perspectives - Obesity Induced by The Neurological Drugs - Molecular Mechanism of Nervous System Disorders and Implications for New Therapeutic Targets - Glioma Imaging and Novel Agents - Screening Models for Neuroleptic Drug-Induced Hyperprolactinemia: A Mini-Review.

Frontiers in Clinical Drug Research-Diabetes and Obesity: Volume 7

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Publisher : Bentham Science Publishers
ISBN 13 : 9815123599
Total Pages : 228 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Frontiers in Clinical Drug Research-Diabetes and Obesity: Volume 7 by : Shazia Anjum

Download or read book Frontiers in Clinical Drug Research-Diabetes and Obesity: Volume 7 written by Shazia Anjum and published by Bentham Science Publishers. This book was released on 2023-03-21 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affective computing is an emerging field situated at the intersection of artificial intelligence and behavioral science. Affective computing refers to studying and developing systems that recognize, interpret, process, and simulate human emotions. It has recently seen significant advances from exploratory studies to realworld applications. Multimodal Affective Computing offers readers a concise overview of the stateoftheart and emerging themes in affective computing, including a comprehensive review of the existing approaches in applied affective computing systems and social signal processing. It covers affective facial expression and recognition, affective body expression and recognition, affective speech processing, affective text, and dialogue processing, recognizing affect using physiological measures, computational models of emotion and theoretical foundations, and affective sound and music processing. This book identifies future directions for the field and summarizes a set of guidelines for developing nextgeneration affective computing systems that are effective, safe, and humancentered.The book is an informative resource for academicians, professionals, researchers, and students at engineering and medical institutions working in the areas of applied affective computing, sentiment analysis, and emotion recognition.

A Blueprint for the Hard Problem of Consciousness

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Publisher : Bentham Science Publishers
ISBN 13 : 1681087677
Total Pages : 251 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis A Blueprint for the Hard Problem of Consciousness by : Paulo J. Negro

Download or read book A Blueprint for the Hard Problem of Consciousness written by Paulo J. Negro and published by Bentham Science Publishers. This book was released on 2019-02-11 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Blueprint for the Hard Problem of Consciousness addresses the fundamental mechanism that allows physical events to transcend into subjective experiences, termed the Hard Problem of Consciousness. Consciousness is made available as the abstract product of self-referent realization of information by strange loops through the levels of processing of the brain. Readers are introduced to the concept of the Hard Problem of Consciousness and related concepts followed by a critical discourse of different theories of consciousness. Next, the author identifies the fundamental flaw of the Integrated Information Theory (IIT) and proposes an alternative that avoids the cryptic intelligent design and panpsychism of the IIT. This author also demonstrates how something can be created out of nothing without resorting to quantum theory, while pointing out neurobiological alternatives to the bottom-up approach of quantum theories of consciousness. The book then delves into the philosophy of qualia in different physiological knowledge networks (spatial, temporal and olfactory, cortical signals, for example) to explain an action-based model consistent with the generational principles of Predictive Coding, which maps prediction and predictive-error signals for perceptual representations supporting integrated goal-directed behaviors. Conscious experiences are considered the outcome of abstractions realized out of map overlays and provided by sustained oscillatory activity. The key feature of this blueprint is that it offers a perspective of the Hard Problem of Consciousness from the point of view of the subject; the experience of ‘being the subject’ is predicted to be the realization of inference inversely mapped out of hidden causes of global integrated actions. The author explains the consistencies of his blueprint with ideas of the Global Neuronal Workspace and the Adaptive Resonance Theory of consciousness as well as with the empirical evidence supporting the Integrated Information Theory. A Blueprint for the Hard Problem of Consciousness offers a unique perspective to readers interested in the scientific philosophy and cognitive neuroscience theory in relation to models of the theory of consciousness.

Mechanisms of Neuronal Recovery in the Central Nervous System

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Publisher : Frontiers Media SA
ISBN 13 : 2889714705
Total Pages : 255 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Mechanisms of Neuronal Recovery in the Central Nervous System by : Luis B. Tovar-y-Romo

Download or read book Mechanisms of Neuronal Recovery in the Central Nervous System written by Luis B. Tovar-y-Romo and published by Frontiers Media SA. This book was released on 2021-10-13 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Frontiers in Clinical Drug Research - Hematology

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Publisher : Bentham Science Publishers
ISBN 13 : 1681083671
Total Pages : 272 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Frontiers in Clinical Drug Research - Hematology by : Atta-ur-Rahman

Download or read book Frontiers in Clinical Drug Research - Hematology written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2018-04-05 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology. The third volume of this series features 6 reviews: -Advances in the understanding and treatment of immune thrombocytopenia -Recent developments in chronic myeloid leukemia biology and treatment -Role of immunomodulatory drugs in the treatment of lymphoid and myeloid malignancies -Pediatric hematological malignancies – clinical manifestation, treatment and follow-up -Novel therapies and immunotherapeutic approaches to treat childhood leukemia -Erythrocyte turnover and erythropoietic patterns in two different experimental mouse models of anemia.

Sleep Disorders and Sleep Deprivation

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Publisher : National Academies Press
ISBN 13 : 0309101115
Total Pages : 425 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine

Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Pain Management and the Opioid Epidemic

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Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies

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Publisher : Frontiers Media SA
ISBN 13 : 2889631141
Total Pages : 138 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies by : Qasem Ramadan

Download or read book Medical and Industrial Applications of Microfluidic-based Cell/Tissue Culture and Organs-on-a-Chip: Advances in Organs-on-a-Chip and Organoids Technologies written by Qasem Ramadan and published by Frontiers Media SA. This book was released on 2019-10-16 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific disciplines with industrial and clinical applications. In particular, organotypic cell culture and its integration in microfluidic devices would enable the realization of “in vivo-like” cell microenvironment within systems that are more amenable to automation and integration. Such remarkable advancement forms the foundation and motivation to transfer research from the laboratory to the field. Although the microfluidics and cell culture technologies have influenced many areas of science, significant research efforts are currently focus on finding methods to transform drug screening and toxicity testing from a system reliant on high-dose animal studies to one based primarily on human-relevant in vitro models. In line with regulatory developments precluding the use of animal testing, as well as fundamental differences in animal versus human, human in vitro methodologies are required to replace the animal-based testes while permitting physiologically relevant model equivalents for superior prediction. Organs-on-a-chip is an ambitious and rapidly growing technology that promise to bridge the gap between in vivo and in vitro studies and open wide possibilities in medical and industrial applications. However, many challenges are still ahead. This eBook present recent state-of-the-art works and critical reviews in organs-on-a-chip technology which highlight the new advances in this growing field with an emphasis on the interface between technological advancements and high impact applications.